Polymorphism of A133S and promoter hypermethylation in Ras association domain family 1A gene (RASSF1A) is associated with risk of esophageal and gastric cardia cancers in Chinese population from high incidence area in northern China

BMC Cancer

Volumn 13, Issue , 2013, Pages

  Zhou, Sheng Li ^a   Cui, Juan ^b   Fan, Zong Min ^a   Li, Xue Min ^c   Li, Ji Li ^d   Liu, Bao Chi ^e   Zhang, Dong Yun ^a   Liu, Hong Yan ^f   Zhao, Xue Ke ^a   Song, Xin ^a   Wang, Ran ^a   Yan, Ze Chen ^a   Yi, Hui Xing ^a   Wang, Li Dong ^a  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^b XINXIANG MEDICAL UNIVERSITY   (China)

^c Department of Pathology   (China)

^d Linzhou Cancer Hospital   (China)

^e SHANGHAI PUBLIC HEALTH CLINICAL CENTER   (China)

^f ZHENGZHOU UNIVERSITY   (China)

Author keywords

A133S in RASSF1A; Esophageal squamous cell carcinoma; Gastric cardia adenocarcinoma; Methylation; Polymorphism; Protein expression

Indexed keywords

RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; RASSF1 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ADULT; AGE; ARTICLE; CANCER INCIDENCE; CARDIA CARCINOMA; CHINA; CONTROLLED STUDY; DNA METHYLATION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PREVALENCE; PROMOTER REGION; PROTEIN EXPRESSION; RAS ASSOCIATION DOMAIN FAMILY 1A GENE; TUMOR SUPPRESSOR GENE; ADENOCARCINOMA; CARCINOMA, SQUAMOUS CELL; CARDIA; ESOPHAGEAL NEOPLASMS; GENETIC PREDISPOSITION; GENETICS; INCIDENCE; MIDDLE AGED; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; STOMACH NEOPLASMS;

ADENOCARCINOMA; CARCINOMA, SQUAMOUS CELL; CARDIA; CHINA; DNA METHYLATION; ESOPHAGEAL NEOPLASMS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IMMUNOHISTOCHEMISTRY; INCIDENCE; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK FACTORS; STOMACH NEOPLASMS; TUMOR SUPPRESSOR PROTEINS;

EID: 84878009282     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-259     Document Type: Article

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