Interval tuning in the primate medial premotor cortex as a general timing mechanism

Journal of Neuroscience

Volumn 33, Issue 21, 2013, Pages 9082-9096

  Merchant, Hugo ^a   Pérez, Oswaldo ^a   Zarco, Wilbert ^a   Gámez, Jorge ^a  

^a INSTITUTO DE NEUROBIOLOGÍA   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUDITORY STIMULATION; CORTICAL SYNCHRONIZATION; INTERVAL TUNING; MALE; MOTOR PERFORMANCE; NERVE CELL; NEURAL RECORDING; NONHUMAN; PREMOTOR CORTEX; PRIORITY JOURNAL; RHESUS MONKEY; RHYTHM; STATISTICAL ANALYSIS; TASK PERFORMANCE; TIME PERCEPTION; VISUAL STIMULATION;

ACTION POTENTIALS; ANALYSIS OF VARIANCE; ANIMALS; BRAIN MAPPING; CELL COUNT; ELECTROENCEPHALOGRAPHY PHASE SYNCHRONIZATION; FUNCTIONAL LATERALITY; MACACA MULATTA; MALE; MOTOR CORTEX; NEURONS; PSYCHOMOTOR PERFORMANCE; REACTION TIME; REGRESSION ANALYSIS; TIME PERCEPTION;

EID: 84877999506     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5513-12.2013     Document Type: Article

References (66)

1. Andersen RA, Essick GK, Siegel RM (1985) Encoding of spatial location by posterior parietal neurons. Science 230:456-458.
2. Bartolo R, Merchant H (2009) Learning and generalization of time produc- tion in humans: rules of transfer across modalities and interval durations. Exp Brain Res 197:91-100.
3. Bartolo R, Prado L, Merchant H (2012) The oscillatory activity of the pri- mate putamen is associated with the temporal and sequential structure of a synchronization-continuation tapping task. Paper presented at 42nd Congress of the Society for Neuroscience, New Orleans, LA, October.
4. Brody CD, Hernández A, Zainos A, Romo R (2003) Timing and neural encodingofsomatosensoryparametricworkingmemoryinmacaquepre- frontal cortex. Cereb Cortex 13:1196-1207.
5. Bueti D, Walsh V, Frith C, Rees G (2008) Different brain circuits underlie motor and perceptual representations of temporal intervals. J Cogn Neu- rosci 20:204-214.
6. Buhusi CV, Meck WH (2005) What makes us tick? Functional and neural mechanisms of interval timing. Nat Rev Neurosci 6:755-765.
7. Buonomano DV, Laje R (2010) Population clocks: motor timing with neu- ral dynamics. Trends Cogn Sci 14:520-527.
8. Coull JT, Cheng RK, Meck WH (2011) Neuroanatomical and neurochemi- cal substrates of timing. Neuropsychopharmacology 36:3-25.
9. Dayan P, Abbott LF (2001) Theoretical neuroscience, computational and mathematical modeling of neural systems. London: MIT.
10. deCharms RC, Zador A (2000) Neural representation and the cortical code. Annu Rev Neurosci 23:613-647.
11. Dickey AS, Suminski A, Amit Y, Hatsopoulos NG (2009) Single-unit stabil- ity using chronically implanted multielectrode arrays. J Neurophysiol 102:1331-1339.
12. Diehl RL, Lotto AJ, Holt LL (2004) Speech perception. Annu Rev Psychol 55:149-179.
13. Draper NR, Smith H (1981) Applied regression analysis. New York: Wiley.
14. Genovesio A, Tsujimoto S, Wise SP (2009) Feature-and order-based timing representations in the frontal cortex. Neuron 63:254-266.
15. Georgopoulos AP, Schwartz AB, Kettner RE (1986) Neuronal population coding of movement direction. Science 233:1416-1419.
16. Gibbon J, Malapani C, Dale CL, Gallistel C (1997) Toward a neurobiology of temporal cognition: advances and challenges. Curr Opin Neurobiol 7:170-184.
17. Hanes DP, Thompson KG, Schall JD (1995) Relationship of presaccadic activity in frontal eye field and supplementary eye field to saccade initia- tion in macaque: Poisson spike train analysis. Exp Brain Res 103:85-96.
18. Harrington DL, Zimbelman JL, Hinton SC, Rao SM (2010) Neural modu- lation of temporal encoding, maintenance, and decision processes. Cereb Cortex 20:1274-1285.
19. Hastie T, Tibshirani R, Friedman J (2001) The elements of statistical learn- ing: data mining, inference, and prediction. New York: Springer.
20. Heron J, Aaen-Stockdale C, Hotchkiss J, Roach NW, McGraw PV, Whitaker D (2012) Duration channels mediate human time perception. Proc Biol Sci 279:690-698.
21. Ivry RB (1996) The representation of temporal information in perception and motor control. Curr Opin Neurobiol 6:851-857.
22. Ivry RB, Hazeltine RE (1995) Perception and production of temporal inter- vals across a range of durations: evidence of a common timing mecha- nism. J Exp Psychol Hum Perform 21:3-18.
23. Janata P, Grafton ST (2003) Swinging in the brain: shared neural substrates for behaviors related to sequencing and music. Nat Neurosci 6:682-687.
24. Jin DZ, Fujii N, Graybiel AM (2009) Neural representation of time in cortico-basalgangliacircuits. ProcNatlAcadSciU S A106:19156-19161.
25. Johnson RA, Wichern DW (1998) Applied multivariate statistical analysis. Upper Saddle River, NJ: Prentice Hall.
26. Karmarkar UR, Buonomano DV (2007) Timing in the absence of clocks: encoding time in neural network states. Neuron 53:427-438.
27. Keele S, Nicoletti R, Ivry R, Pokorny R (1989) Mechanisms of perceptual timing: beat-based or interval-based judgments? Psychol Res 50:251-256.
28. Kermadi I, Joseph JP (1995) Activity in the caudate nucleus of monkey dur-ing spatial sequencing. J Neurophysiol 74:911-933.
29. Lebedev MA, O'Doherty JE, Nicolelis MA (2008) Decoding of temporal in-tervals from cortical ensemble activity. J Neurophysiol 99:166-186.
30. Leon MI, Shadlen MN (2003) Representation of time by neurons in the posterior parietal cortex of the macaque. Neuron 38:317-327.
31. Logothetis NK, Sheinberg DL (1996) Visual object recognition. Annu Rev Neurosci 19:577-621.
32. Macar F, Coull J, Vidal F (2006) The supplementary motor area in motor and perceptual time processing: fMRI studies. Cogn Process 7:89-94.
33. Maimon G, Assad JA (2006) A cognitive signal for the proactive timing of action in macaque LIP. Nat Neurosci 9:948-955.
34. Matell MS, Meck WH (2004) Cortico-striatal circuits and interval timing: coincidence detection of oscillatory processes. Brain Res Cogn Brain Res 21:139-170.
35. Matell MS, Meck WH, Nicolelis MA (2003a) Interval timing and the encod-ing of signal duration by ensembles of cortical and striatal neurons. Behav Neurosci 117:760-773.
36. Matell MS, Meck WH, Nicolelis MAL (2003b) Integration of behavior and timing: anatomically separate systems or distributed processing? In: Functional and neural mechanisms of interval timing (Meck WH, ed), pp 371-392. Boca Raton, FL: CRC.
37. Meck WH, Penney TB, Pouthas V (2008) Cortico-striatal representation of time in animals and humans. Curr Opin Neurobiol 18:145-152.
38. Meegan DV, Aslin RN, Jacobs RA (2000) Motor timing learned without motor training. Nat Neurosci 3:860-862.
39. Merchant H, Georgopoulos AP (2006) Neurophysiology of perceptual and motor aspects of interception. J Neurophysiol 95:1-13.
40. Merchant H, Perez O (2009) Neurophysiology of interceptive behavior in the primate: encoding and decoding target parameters in the parietofron- tal system. In: Coherent behavior in neural networks (Josic K, Matias M, Romo R, Rubin J, eds), Springer Series in Computational Neuroscience, Vol 3, pp 191-206. New York: Springer.
41. Merchant H, Battaglia-Mayer A, Georgopoulos AP (2004) Neuralresponses during interception of real and apparent circularly moving stimuli in motor cortex and Area 7a. Cereb Cortex 14:314-331.
42. Merchant H, Zarco W, Prado L (2008a) Do we have a common mechanism for measuring time in the hundreds of millisecond range? Evidence from multiple-interval timing tasks. J Neurophysiol 99:939-949.
43. Merchant H, Zarco W, Bartolo R, Prado L (2008b) The context of temporal processing is represented in the multidimensional relationships between timing tasks. PloS One 3:e3169:1-9.
44. Merchant H, Naselaris T, Georgopoulos AP (2008c) Dynamic sculpting of directional tuning in the primate motor cortex during 3D reaching. J Neurosci 28:9164-9172.
45. Merchant H, Zarco W, Pérez O, Prado L, Bartolo R (2011) Measuringtimewith different neural chronometers during a synchronization-continuation task. Proc Natl Acad Sci U S A 108:19784-19789.
46. Merchant H, de Lafuente V, Peña-Ortega F, Larriva-Sahd J (2012) Functional impactofinterneuronalinhibitioninthecerebralcortexofbehavinganimals. Prog Neurobiol 99:163-178.
47. Merchant H, Harrington D, Meck WH (2013) Neural basis of the percep- tion and estimation of time. Annu Rev Neurosci, in press.
48. Mita A, Mushiake H, Shima K, Matsuzaka Y, Tanji J (2009) Interval time coding by neurons in the presupplementary and supplementary motor areas. Nat Neurosci 12:502-507.
49. di Z, Rand MK (1997) Differen-tial roles of monkey striatum in learning of sequential hand movement. Exp Brain Res 115:1-5.
50. Nagarajan SS, Blake DT, Wright BA, Byl N, Merzenich MM (1998) Practice-related improvements in somatosensory interval discrimination are tem-porally specific but generalize across skin location, hemisphere, and modality. J Neurosci 18:1559-1570.
51. Nieder A, Diester I, Tudusciuc O (2006) Temporal and spatial enumeration processes in the primate parietal cortex. Science 313:1431-1435.
52. Perez O, Kass RE, Merchant H (2013) Trial time warping to discriminate stimulus-related from movement-related neural activity. J Neurosci Methods 212:203-210.
53. Phillips-Silver J, Trainor LJ (2005) Feeling the beat: movement influences infant rhythm perception. Science 308:1430.
54. Rakitin BC, Gibbon J, Penney TB, Malapani C, Hinton SC, Meck WH (1998) Scalar expectancy theory and peak-interval timing in humans. J Exp Psy- chol Anim Behav Process 24:15-33.
55. Renoult L, Roux S, Riehle A (2006) Time is a rubberband: neuronal activity in monkey motor cortex in relation to time estimation. Eur J Neurosci 23:3098-3108.
56. Sadagopan S, Wang X (2008) Level invariant representation of sounds by populations of neurons in primary auditory cortex. J Neurosci 28:3415-3426.
57. Salinas E, Thier P (2000) Gain modulation: a major computational princi- ple of the central nervous system. Neuron 27:15-21.
58. Shima K, Tanji J (1998) Both supplementary and presupplementary motor areas are crucial for the temporal organization of multiple movements. J Neurophysiol 80:3247-3260.
59. Sohn JW, Lee D (2007) Order-dependent modulation of directional signals in the supplementary and presupplementary motor areas. J Neurosci 27: 13655-13666.
60. Tanaka M (2007) Cognitive signals in the primate motor thalamus predict saccade timing. J Neurosci 27:12109-12118.
61. Tanji J (2001) Sequential organization of multiple movements: involve- ment of cortical motor areas. Annu Rev Neurosci 24:631-651.
62. Tanji J, Shima K (1994) Role for supplementary motor area cells in plan ning several movements ahead. Nature 371:413-416.
63. Treue S, Martínez Trujillo JC (1999) Feature-based attention influences motion processing gain in macaque visual cortex. Nature 399:575-579.
64. Walsh V (2003) A theory of magnitude: common cortical metrics of time, space and quantity. Trends Cogn Sci 7:483-488.
65. Wiener M, Turkeltaub P, Coslett HB (2010) The image of time: a voxel-wise meta-analysis. Neuroimage 49:1728-1740.
66. Zarco W, Merchant H, Prado L, Mendez JC (2009) Subsecond timing in primates: comparison of interval production between human subjects and rhesus monkeys. J Neurophysiol 102:3191-3202.