-
1
-
-
34249697099
-
Forecasting the global burden of alzheimer's disease
-
Brookmeyer, R.; Johnson, E.; Ziegler-Graham, K.; Arrighi, H. M. Forecasting the global burden of Alzheimer's disease. Alzheimer's Dementia, 2007, 3, 186.
-
(2007)
Alzheimer's Dementia
, vol.3
, pp. 186
-
-
Brookmeyer, R.1
Johnson, E.2
Ziegler-Graham, K.3
Arrighi, H.M.4
-
2
-
-
20744447947
-
Stroke epidemiology in the developing world
-
Feigin, V. L. Stroke epidemiology in the developing world. Lancet, 2005, 365, 2160.
-
(2005)
Lancet
, vol.365
, pp. 2160
-
-
Feigin, V.L.1
-
3
-
-
0036263210
-
Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part ii: Suppression of astrocytic activation by a novel agent (r)-()-2-propyloctanoic acid (ono-2506) leads to mitigation of delayed infarct expansion and early improvement of neurologic deficits
-
Tateishi, N.; Mori, T.; Kagamiishi, Y.; Satoh, S.; Katsube, N.; Morikawa, E.; Morimoto, T.; Matsui, T.; Asano, T. Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part ii: Suppression of astrocytic activation by a novel agent (R)-()-2-propyloctanoic acid (ONO-2506) leads to mitigation of delayed infarct expansion and early improvement of neurologic deficits. J. Cereb. Blood Flow Metab., 2002, 22, 723.
-
(2002)
J. Cereb. Blood Flow Metab
, vol.22
, pp. 723
-
-
Tateishi, N.1
Mori, T.2
Kagamiishi, Y.3
Satoh, S.4
Katsube, N.5
Morikawa, E.6
Morimoto, T.7
Matsui, T.8
Asano, T.9
-
4
-
-
3242892633
-
Arundic acid: Astrocyte-modulating agent, treatment of stroke, treatment of neurodegeneration
-
Sorbera, L. A.; Castaner, J.; Castaner, J. M. Arundic acid: Astrocyte-modulating agent, treatment of stroke, treatment of neurodegeneration. Drugs Future, 2004, 29, 441.
-
(2004)
Drugs Future
, vol.29
, pp. 441
-
-
Sorbera, L.A.1
Castaner, J.2
Castaner, J.M.3
-
5
-
-
18044369530
-
Modulating effects of ono-2506 on astrocytic activation in cultured astrocytes from rat cerebrum
-
Shinagawa, R.; Tateishi, N.; Shimoda, T.; Maekawa, H.; Yada, N.; Akiyama, T.; Matsuda, S.; Katsube, N. Modulating effects of ONO-2506 on astrocytic activation in cultured astrocytes from rat cerebrum. Soc. Neurosci. Abs., 1999, 25, 843.10.
-
(1999)
Soc. Neurosci. Abs
, vol.25
, pp. 84310
-
-
Shinagawa, R.1
Tateishi, N.2
Shimoda, T.3
Maekawa, H.4
Yada, N.5
Akiyama, T.6
Matsuda, S.7
Katsube, N.8
-
6
-
-
0142062313
-
Inhibitory effect of ono-2506 on gaba receptor disappearance in cultured astrocytes and ischemic brain
-
Katsumata, S.; Tateishi, N.; Kagamiishi, Y.; Shintaku, K.; Hayakawa, T.; Shimoda, T.; Shinagawa, R.; Akiyama, T.; Katsube, N. Inhibitory effect of ONO-2506 on GABA receptor disappearance in cultured astrocytes and ischemic brain. Soc. Neurosci. Abs., 1999, 25, 843.11.
-
(1999)
Soc. Neurosci. Abs
, vol.25
, pp. 84311
-
-
Katsumata, S.1
Tateishi, N.2
Kagamiishi, Y.3
Shintaku, K.4
Hayakawa, T.5
Shimoda, T.6
Shinagawa, R.7
Akiyama, T.8
Katsube, N.9
-
7
-
-
0009142748
-
Ono-2506, a novel astrocyte modulating agent, suppresses the increase of cox-2 and inos mrna expression in cultured astrocytes and ischemic brain
-
Shimoda, T.; Tateishi, K.; Shintaku, K.; Yada, N.; Katagi, J.; Akiyama, T.; Maekawa, H.; Shinagawa, R.; Kondo, K. ONO-2506, a novel astrocyte modulating agent, suppresses the increase of COX-2 and iNOS mRNA expression in cultured astrocytes and ischemic brain. Soc. Neurosci. Abs., 1998, 24, 384.13.
-
(1998)
Soc. Neurosci. Abs
, vol.24
, pp. 38413
-
-
Shimoda, T.1
Tateishi, K.2
Shintaku, K.3
Yada, N.4
Katagi, J.5
Akiyama, T.6
Maekawa, H.7
Shinagawa, R.8
Kondo, K.9
-
8
-
-
0009274003
-
Ono-2506 ameliorates neurodegeneration through inhibition of reduction of glt-1 expression
-
Shinagawa, R.; Tateishi, N.; Shimoda, T.; Shintaku, K.; Yada, N.; Honjo, K. Kagamiishi, Y.; Kondo, K. ONO-2506 ameliorates neurodegeneration through inhibition of reduction of GLT-1 expression. Soc Neurosci Abs., 1998, 24, 384.14.
-
(1998)
Soc Neurosci Abs
, vol.24
, pp. 38414
-
-
Shinagawa, R.1
Tateishi, N.2
Shimoda, T.3
Shintaku, K.4
Yada, N.5
Honjo, K.6
Kagamiishi, Y.7
Kondo, K.8
-
9
-
-
0032879765
-
Longitudinal magnetic resonance imaging study of perfusion and diffusion in stroke: Evolution of lesion volume and correlation with clinical outcome
-
Beaulieu, C.; de Crespigny, A.; Tong, D. C.; Moseley, M. E.; Albers, G. W.; Marks, M. P. Longitudinal magnetic resonance imaging study of perfusion and diffusion in stroke: Evolution of lesion volume and correlation with clinical outcome. Ann. Neurol., 1999, 46, 568.
-
(1999)
Ann. Neurol
, vol.46
, pp. 568
-
-
Beaulieu, C.1
De Crespigny, A.2
Tong, D.C.3
Moseley, M.E.4
Albers, G.W.5
Marks, M.P.6
-
10
-
-
0030108525
-
Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism
-
Chao, C. C.; Hu, S.; Sheng, W. S.; Bu, D.; Bukrinsky, M. L.; Peterson, P. K. Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism. Glia, 1996, 16, 276.
-
(1996)
Glia
, vol.16
, pp. 276
-
-
Chao, C.C.1
Hu, S.2
Sheng, W.S.3
Bu, D.4
Bukrinsky, M.L.5
Peterson, P.K.6
-
11
-
-
0029671449
-
S-100 Stimulates inducible nitric oxide synthase activity and mrna levels in rat cortical astrocytes
-
Hu, J.; Castets, F.; Guevara, J. L.; Van Eldik, L. J. S-100 stimulates inducible nitric oxide synthase activity and mRNA levels in rat cortical astrocytes. J. Biol. Chem., 1996, 271, 2543.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 2543
-
-
Hu, J.1
Castets, F.2
Guevara, J.L.3
Van Eldik, L.J.4
-
12
-
-
0030613810
-
S-100 Induces neuronal cell death through nitric oxide release from astrocytes
-
Hu, J.; Ferreira, A.; Van Eldik, L. J. S-100 induces neuronal cell death through nitric oxide release from astrocytes. J. Neurochem., 1997, 69, 2294.
-
(1997)
J. Neurochem
, vol.69
, pp. 2294
-
-
Hu, J.1
Ferreira, A.2
Van Eldik, L.J.3
-
13
-
-
0033986453
-
Production of nitric oxide by glial cells: Regulation and potential roles in the cns
-
Murphy, S. Production of nitric oxide by glial cells: Regulation and potential roles in the CNS. Glia, 2000, 29, 1.
-
(2000)
Glia
, vol.29
, pp. 1
-
-
Murphy, S.1
-
14
-
-
84888138690
-
Functional modulation of astrocytes by a novel agent ono-2506 mitigates delayed infarct expansion with a wide therapeutic time window, inducing prompt neurological recovery through reduction of the extracellular level of glutamate
-
Asano, T.; Tateishib, N. N.; Matsuia, T.; Moria, T.; Kagamiishib, Y.; Satob, S.; Katsubeb, N. Functional modulation of astrocytes by a novel agent ONO-2506 mitigates delayed infarct expansion with a wide therapeutic time window, inducing prompt neurological recovery through reduction of the extracellular level of glutamate. Int. Congr. Ser., 2003, 1252, 147.
-
(2003)
Int. Congr. Ser
, vol.1252
, pp. 147
-
-
Asano, T.1
Tateishib, N.N.2
Matsuia, T.3
Moria, T.4
Kagamiishib, Y.5
Satob, S.6
Katsubeb, N.7
-
15
-
-
0345118197
-
Protection of dopaminergic neurons with a novel astrocyte modulating agent (r)-(-)-2-propyloctanoic acid (ono-2506) in an mptp-mouse model of parkinson's disease
-
Kato, H.; Araki, T.; Imai, Y.; Takahashi, Y.; Itoyama, Y. Protection of dopaminergic neurons with a novel astrocyte modulating agent (R)-(-)-2-propyloctanoic acid (ONO-2506) in an MPTP-mouse model of Parkinson's disease. J. Neurol. Sci., 2003, 208, 9.
-
(2003)
J. Neurol. Sci
, vol.208
, pp. 9
-
-
Kato, H.1
Araki, T.2
Imai, Y.3
Takahashi, Y.4
Itoyama, Y.5
-
16
-
-
9444290802
-
Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against mptp neurotoxicity in mice
-
Kato, H.; Kurosaki, R.; Oki, C.; Araki, T. Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTP neurotoxicity in mice. Brain Res., 2004, 1030, 66.
-
(2004)
Brain Res
, vol.1030
, pp. 66
-
-
Kato, H.1
Kurosaki, R.2
Oki, C.3
Araki, T.4
-
17
-
-
31844442743
-
Neuroprotective effect of arundic acid, an astrocytemodulating agent, in mouse brain against mptp (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity
-
Himeda, T.; Kadoguchi, N.; Kamiyama, Y.; Kato, H.; Maegawa, H.; Araki, T. Neuroprotective effect of arundic acid, an astrocytemodulating agent, in mouse brain against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity. Neuropharmacol., 2006, 50, 329.
-
(2006)
Neuropharmacol
, vol.50
, pp. 329
-
-
Himeda, T.1
Kadoguchi, N.2
Kamiyama, Y.3
Kato, H.4
Maegawa, H.5
Araki, T.6
-
18
-
-
0001496694
-
A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by n-methyl-4-phenyl-1, 2, 3,6-tetrahydropyridine
-
Burns, R. S.; Chiueh, C. C.; Markey, S. P.; Ebert, M. H.; Jacobowitz, D. M.; Kopin, I. J. A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc. Natl. Acad. Sci. USA., 1983, 80, 4546.
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 4546
-
-
Burns, R.S.1
Chiueh, C.C.2
Markey, S.P.3
Ebert, M.H.4
Jacobowitz, D.M.5
Kopin, I.J.6
-
19
-
-
0021280826
-
Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1, 2, 5,6-tetrahydropyridine in mice
-
Heikkila, R. E.; Hess, A.; Duvoisin, R. C. Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice. Science, 1984, 224, 1451.
-
(1984)
Science
, vol.224
, pp. 1451
-
-
Heikkila, R.E.1
Hess, A.2
Duvoisin, R.C.3
-
20
-
-
0020680904
-
Chronic parkinsonism in humans due to a product of meperidine-Analog synthesis
-
Langston, J. W.; Ballard, P.; Tetrud, J. W.; Irwin, I. Chronic parkinsonism in humans due to a product of meperidine-Analog synthesis. Science, 1983, 219, 979.
-
(1983)
Science
, vol.219
, pp. 979
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
21
-
-
40349116494
-
Delayed treatment with arundic acid reduces the mptpinduced neurotoxicity in mice
-
Oki, C.; Watanabe, Y.; Yokoyama, H.; Shimoda, T.; Kato, H, Araki, T. Delayed treatment with arundic acid reduces the MPTPinduced neurotoxicity in mice. Cell Mol. Neurobiol., 2008, 28, 417.
-
(2008)
Cell Mol. Neurobiol
, vol.28
, pp. 417
-
-
Oki, C.1
Watanabe, Y.2
Yokoyama, H.3
Shimoda, T.4
Kato, H.5
Araki, T.6
-
22
-
-
18944386772
-
Modulation of astrocytic activation by arundic acid (ono-2506) mitigates detrimental effects of the apolipoprotein e4 isoform after permanent focal ischemia in apolipoprotein e knock-in mice
-
Mori, T.; Town, T.; Tan, J.; Tateishi, N.; Asano, T. Modulation of astrocytic activation by arundic acid (ONO-2506) mitigates detrimental effects of the apolipoprotein E4 isoform after permanent focal ischemia in apolipoprotein E knock-in mice. Cereb. Blood Flow Metab., 2005, 25, 748.
-
(2005)
Cereb. Blood Flow Metab
, vol.25
, pp. 748
-
-
Mori, T.1
Town, T.2
Tan, J.3
Tateishi, N.4
Asano, T.5
-
23
-
-
0034639675
-
Altered cholesterol metabolism in human apolipoprotein e4 knock-in mice
-
Hamanaka, H.; Katoh-Fukui, Y.; Suzuki, K.; Kobayashi, M.; Suzuki, R.; Motegi, Y.; Nakahara, Y.; Takeshita, A.; Kawai, M.; Ishiguro, K.; Yokoyama, M.; Fujita S. C. Altered cholesterol metabolism in human apolipoprotein E4 knock-in mice. Hum. Mol. Genet., 2000, 9, 353.
-
(2000)
Hum. Mol. Genet
, vol.9
, pp. 353
-
-
Hamanaka, H.1
Katoh-Fukui, Y.2
Suzuki, K.3
Kobayashi, M.4
Suzuki, R.5
Motegi, Y.6
Nakahara, Y.7
Takeshita, A.8
Kawai, M.9
Ishiguro, K.10
Yokoyama, M.11
Fujita, S.C.12
-
24
-
-
0037339577
-
Increased vulnerability to focal ischemic brain injury in human apolipoprotein e4 knock-in mice
-
Mori, T.; Kobayashi, M.; Town, T.; Fujita, S. C.; Asano, T. Increased vulnerability to focal ischemic brain injury in human apolipoprotein E4 knock-in mice. J. Neuropathol. Exp. Neurol., 2003, 62, 280.
-
(2003)
J. Neuropathol. Exp. Neurol
, vol.62
, pp. 280
-
-
Mori, T.1
Kobayashi, M.2
Town, T.3
Fujita, S.C.4
Asano, T.5
-
25
-
-
2442629711
-
Attenuation of a delayed increase in the extracellular glutamate level in the peri-infarct area following focal cerebral ischemia by a novel agent ono-2506
-
Mori, T.; Tateishi, N.; Kagamiishi, Y.; Shimoda, T; Satoh, S.; Ono, S.; Katsube, N.; Asano, T. Attenuation of a delayed increase in the extracellular glutamate level in the peri-infarct area following focal cerebral ischemia by a novel agent ONO-2506. Neurochem. Int., 2004, 45, 381.
-
(2004)
Neurochem. Int
, vol.45
, pp. 381
-
-
Mori, T.1
Tateishi, N.2
Kagamiishi, Y.3
Shimoda, T.4
Satoh, S.5
Ono, S.6
Katsube, N.7
Asano, T.8
-
26
-
-
33745932262
-
Arundic acid ameliorates cerebral amyloidosis and gliosis in alzheimer transgenic mice
-
Mori, T.; Town, T.; Tan, J.; Yada, N.; Horikoshi, Y.; Yamamoto, J. Shimoda, T, Kamanaka, Y.; Tateishi, N.; Asano T. Arundic acid ameliorates cerebral amyloidosis and gliosis in Alzheimer transgenic mice. J. Pharmacol. Exp. Ther., 2006, 318, 571.
-
(2006)
J. Pharmacol. Exp. Ther
, vol.318
, pp. 571
-
-
Mori, T.1
Town, T.2
Tan, J.3
Yada, N.4
Horikoshi, Y.5
Yamamoto, J.6
Shimoda, T.7
Kamanaka, Y.8
Tateishi, N.9
Asano, T.10
-
27
-
-
33846641320
-
Expression of s-100 protein and protective effect of arundic acid on the rat brain in chronic cerebral hypoperfusion
-
Ohtani, R.; Tomimoto, H.; Wakita, H.; Kitaguchi,H.; Nakaji, K.; Takahashi, R. Expression of S-100 protein and protective effect of arundic acid on the rat brain in chronic cerebral hypoperfusion. Brain Res., 2007, 1135, 195.
-
(2007)
Brain Res
, vol.1135
, pp. 195
-
-
Ohtani, R.1
Tomimoto, H.2
Wakita, H.3
Kitaguchi, H.4
Nakaji, K.5
Takahashi, R.6
-
28
-
-
70349229193
-
Immunohistochemical analysis of brain lesions using s-100 and glial fibrillary acidic protein antibodies in arundic acid-(ono-2506) treated stroke-prone spontaneously hypertensive rats
-
Higashino, H.; Niwa, A.; Satou, T.; Ohta, Y.; Hashimoto, S.; Tabuchi, M.; Ooshima, K. Immunohistochemical analysis of brain lesions using S-100 and glial fibrillary acidic protein antibodies in arundic acid-(ONO-2506) treated stroke-prone spontaneously hypertensive rats. J. Neural. Transm., 2009, 116, 1209.
-
(2009)
J. Neural. Transm
, vol.116
, pp. 1209
-
-
Higashino, H.1
Niwa, A.2
Satou, T.3
Ohta, Y.4
Hashimoto, S.5
Tabuchi, M.6
Ooshima, K.7
-
29
-
-
0028300555
-
Increased basic fibroblast growth factor immunoreactivity in the brain of stroke-prone spontaneously hypertensive rats
-
Kataoka, H.; Yamada, E.; Hazama, F. Increased basic fibroblast growth factor immunoreactivity in the brain of stroke-prone spontaneously hypertensive rats. Acta Neuropathol. (Berlin), 1994, 88, 7.
-
(1994)
Acta Neuropathol. (Berlin
, vol.88
, pp. 7
-
-
Kataoka, H.1
Yamada, E.2
Hazama, F.3
-
30
-
-
33846606064
-
Evidence for a wide extraastrocytic distribution of s-100 in human brain
-
Steiner, J.; Bernstein, H. G.; Bielau, H.; Berndt, A.; Brisch, R.; Mawrin, C.; Keilhoff, G.; Bogerts, B. Evidence for a wide extraastrocytic distribution of S-100 in human brain. BMC Neurosci., 2007, 8, 2.
-
(2007)
BMC Neurosci
, vol.8
, pp. 2
-
-
Steiner, J.1
Bernstein, H.G.2
Bielau, H.3
Berndt, A.4
Brisch, R.5
Mawrin, C.6
Keilhoff, G.7
Bogerts, B.8
-
31
-
-
33751252221
-
Safety and tolerability of arundic acid in acute ischemic stroke
-
Pettigrew, L. C.; Kasner, S. E.; Albers, G. W.; Gorman, M.; Grotta, J. C.; Sherman, D. G.; Funakoshi, Y.; Funakoshi, H. Safety and tolerability of arundic acid in acute ischemic stroke. J. Neurol. Sci. 2006, 251, 50.
-
(2006)
J. Neurol. Sci
, vol.251
, pp. 50
-
-
Pettigrew, L.C.1
Kasner, S.E.2
Albers, G.W.3
Gorman, M.4
Grotta, J.C.5
Sherman, D.G.6
Funakoshi, Y.7
Funakoshi, H.8
-
32
-
-
33947538172
-
Pharmacokinetics of arundic acid, an astrocyte modulating agent, in acute ischemic stroke
-
Ishibashi, H.; Pettigrew, L. C.; Funakoshi, Y.; Hiramatsu, M. Pharmacokinetics of arundic acid, an astrocyte modulating agent, in acute ischemic stroke. J. Clin. Pharmacol., 2007, 47, 445.
-
(2007)
J. Clin. Pharmacol
, vol.47
, pp. 445
-
-
Ishibashi, H.1
Pettigrew, L.C.2
Funakoshi, Y.3
Hiramatsu, M.4
-
33
-
-
84877937092
-
-
Data presented in Table 1 is taken from
-
Data presented in Table 1 is taken from http://www.clinicaltrials.gov/.
-
-
-
-
34
-
-
84865539649
-
Inhibition of the activation of hepatic stellate cells by arundic acid via the induction of cytoglobin
-
Cui, W.; Wang, M.; Maegawa, H.; Teranishi, Y.; Kawada, N. Inhibition of the activation of hepatic stellate cells by arundic acid via the induction of cytoglobin. Biochem. Biophy. Res. Commun., 2012, 425, 642.
-
(2012)
Biochem. Biophy. Res. Commun
, vol.425
, pp. 642
-
-
Cui, W.1
Wang, M.2
Maegawa, H.3
Teranishi, Y.4
Kawada, N.5
-
35
-
-
84856749602
-
Preparation of optically active 2-propyloctanoic acid as nerve degenerative disease inhibitors
-
Japan Patent 7-98328, 1995
-
Kishimoto, K.; Nakai, H. Preparation of optically active 2-propyloctanoic acid as nerve degenerative disease inhibitors. Japan Patent 7-98328, 1995; Chem. Abstr., 1997, 126, 74487.
-
(1997)
Chem. Abstr
, vol.126
, pp. 74487
-
-
Kishimoto, K.1
Nakai, H.2
-
36
-
-
84856763263
-
Preparation of optically active 2-propyloctanoic acid
-
Japan Patent 7-102693, 1995
-
Kishimoto, K.; Nakai, H. Preparation of optically active 2-propyloctanoic acid. Japan Patent 7-102693, 1995; Chem. Abstr., 1997, 126, 74488.
-
(1997)
Chem. Abstr
, vol.126
, pp. 74488
-
-
Kishimoto, K.1
Nakai, H.2
-
37
-
-
0034100244
-
A practical synthesis of optically active (r)-2-propyloctanoic acid: Therapeutic agent for alzheimer's disease
-
Hasegawa, T.; Yamamoto, H. A practical synthesis of optically active (R)-2-propyloctanoic acid: Therapeutic agent for Alzheimer's disease. Bull. Chem. Soc. Jpn., 2000, 73, 423.
-
(2000)
Bull. Chem. Soc. Jpn
, vol.73
, pp. 423
-
-
Hasegawa, T.1
Yamamoto, H.2
-
38
-
-
0037359554
-
Process development of ono-2506: A therapeutic agent for stroke and alzheimer's disease
-
Hasegawa, T.; Kawanaka, Y.; Kasamatsu, E.; Iguchi, Y.; Yonekawa, Y.; Okamoto, M.; Ohta, C.; Hashimoto, S.; Ohuchida. S. Process development of ono-2506: A therapeutic agent for stroke and Alzheimer's disease. Org. Process. Res. Dev., 2003, 7, 168.
-
(2003)
Org. Process. Res. Dev
, vol.7
, pp. 168
-
-
Hasegawa, T.1
Kawanaka, Y.2
Kasamatsu, E.3
Iguchi, Y.4
Yonekawa, Y.5
Okamoto, M.6
Ohta, C.7
Hashimoto, S.8
Ohuchida, S.9
-
39
-
-
0038726096
-
Development of new chiral auxiliary derived from (s)-(-)-phenylethylamine for a synthesis of enantiopure (r)-2-propyloctanoic acid
-
Hasegawa, T.; Yamamoto, H. Development of new chiral auxiliary derived from (S)-(-)-phenylethylamine for a synthesis of enantiopure (R)-2-propyloctanoic acid. Synthesis, 2003, 1181.
-
Synthesis
, vol.2003
, pp. 1181
-
-
Hasegawa, T.1
Yamamoto, H.2
-
40
-
-
0029743317
-
An improved catalyst system for aromatic carbon-nitrogen bond formation: The possible involvement of bis (phosphine) palladium complexes as key intermediates
-
Wolfe, J. P.; Wagaw, S.; Buchwald, S. L. An improved catalyst system for aromatic carbon-nitrogen bond formation: the possible involvement of bis (phosphine) palladium complexes as key intermediates. J. Am. Chem. Soc., 1996, 118, 7215.
-
(1996)
J. Am. Chem. Soc
, vol.118
, pp. 7215
-
-
Wolfe, J.P.1
Wagaw, S.2
Buchwald, S.L.3
-
41
-
-
0030760535
-
Palladium-catalyzed coupling of optically active amines with aryl bromides
-
Wagaw, S.; Rennels, R. A.; Buchwald, S. L. Palladium-catalyzed coupling of optically active amines with aryl bromides. J. Am. Chem. Soc., 1997, 119, 8451.
-
(1997)
J. Am. Chem. Soc
, vol.119
, pp. 8451
-
-
Wagaw, S.1
Rennels, R.A.2
Buchwald, S.L.3
-
42
-
-
17044424526
-
Synthesis of anti-Alzheimer (r)-arundic acid
-
Pelotier, B.; Holmes, T.; Piva, O. Synthesis of anti-Alzheimer (R)-arundic acid. Tetrahedron: Asymmetry, 2005, 16, 1513.
-
(2005)
Tetrahedron: Asymmetry
, vol.16
, pp. 1513
-
-
Pelotier, B.1
Holmes, T.2
Piva, O.3
-
43
-
-
0026692875
-
Diacetone d-glucose: Efficient chiral building block for asymmetric photodeconjugation
-
Piva, O.; Pete, J.-P. Diacetone D-glucose: Efficient chiral building block for asymmetric photodeconjugation. Tetrahedron: Asymmetry, 1992, 3, 759.
-
(1992)
Tetrahedron: Asymmetry
, vol.3
, pp. 759
-
-
Piva, O.1
Pete, J.-P.2
-
44
-
-
0036178486
-
Asymmetric photodeconjugation: Highly stereoselective synthesis of-fluorocarboxylic derivatives
-
Bargiggia, F.; Dos Santos, S.; Piva, O. Asymmetric photodeconjugation: Highly stereoselective synthesis of-fluorocarboxylic derivatives. Synthesis, 2002, 427.
-
(2002)
Synthesis
, pp. 427
-
-
Bargiggia, F.1
Dos Santos, S.2
Piva, O.3
-
45
-
-
0037756807
-
Anionic versus photochemical diastereoselective deconjugation of diacetone d-glucose ,-unsaturated esters
-
Bargiggia, F.; Piva, O. Anionic versus photochemical diastereoselective deconjugation of diacetone D-glucose ,-unsaturated esters. Tetrahedron: Asymmetry, 2003, 14, 1819.
-
(2003)
Tetrahedron: Asymmetry
, vol.14
, pp. 1819
-
-
Bargiggia, F.1
Piva, O.2
-
46
-
-
28944451806
-
A new process for synthesis of the astrocyte activation suppressor, ono-2506
-
Hasegawa, T.; Kawanaka, Y.; Kasamatsu, E.; Ohta, C.; Nakabayashi, K.; Okamoto, M.; Hamano, M.; Takahashi, T.; Ohuchida, S.; Hamada, Y. A new process for synthesis of the astrocyte activation suppressor, ONO-2506. Org. Process. Res. Dev., 2005, 9, 774.
-
(2005)
Org. Process. Res. Dev
, vol.9
, pp. 774
-
-
Hasegawa, T.1
Kawanaka, Y.2
Kasamatsu, E.3
Ohta, C.4
Nakabayashi, K.5
Okamoto, M.6
Hamano, M.7
Takahashi, T.8
Ohuchida, S.9
Hamada, Y.10
-
47
-
-
0024801485
-
Efficient conversion of nitriles to amides with basic hydrogen peroxide in dimethyl sulfoxide
-
Katritzky, A. R.; Pilarski, B.; Urogdi, L. Efficient conversion of nitriles to amides with basic hydrogen peroxide in dimethyl sulfoxide. Synthesis, 1989, 949.
-
(1989)
Synthesis
, vol.949
-
-
Katritzky, A.R.1
Pilarski, B.2
Urogdi, L.3
-
48
-
-
33846696745
-
Crotylation of (r)-2, 3-cyclohexylideneglyceraldehyde: A simple strategy for the synthesis of enantiopure anti-Alzheimer (r)-Arundic acid
-
Goswami, D.; Chattopadhyay, A. Crotylation of (R)-2,3- cyclohexylideneglyceraldehyde: A simple strategy for the synthesis of enantiopure anti-Alzheimer (R)-Arundic acid. Lett. Org. Chem., 2006, 12, 922.
-
(2006)
Lett. Org. Chem
, vol.12
, pp. 922
-
-
Goswami, D.1
Chattopadhyay, A.2
-
49
-
-
53149108541
-
A concise and efficient route to the alzheimer's therapeutic agent (r)-Arundic acid
-
Garcia, J. M.; Odriozola, J. M.; Lecumberri, A.; Razkin, J.; Gonzalez, A. A concise and efficient route to the Alzheimer's therapeutic agent (R)-Arundic acid. Tetrahedron, 2008, 64, 10664.
-
(2008)
Tetrahedron
, vol.64
, pp. 10664
-
-
Garcia, J.M.1
Odriozola, J.M.2
Lecumberri, A.3
Razkin, J.4
Gonzalez, A.5
-
50
-
-
69749084183
-
A diethyltartrate-based synthesis of both ()-and (+)-Arundic acid
-
Fernandes, R. A.; Dhall, A.; Ingle, A. B. A diethyltartrate-based synthesis of both ()-and (+)-Arundic acid. Tetrahedron Lett., 2009, 50, 5903.
-
(2009)
Tetrahedron Lett
, vol.50
, pp. 5903
-
-
Fernandes, R.A.1
Dhall, A.2
Ingle, A.B.3
-
51
-
-
0001685085
-
Simple stereoselective version of the claisen rearrangement leading to trans-trisubstituted olefinic bonds: Synthesis of squalene
-
Johnson, W. S.; Werthemann, L.; Bartlett, W. R.; Brocksom. T. J.; Li, T.-T.; Faulkner, D. J.; Peterson, M. R. Simple stereoselective version of the Claisen rearrangement leading to trans-trisubstituted olefinic bonds: Synthesis of squalene. J. Am. Chem. Soc., 1970, 92, 741.
-
(1970)
J. Am. Chem. Soc
, vol.92
, pp. 741
-
-
Johnson, W.S.1
Werthemann, L.2
Bartlett, W.R.3
Brocksom, T.J.4
Li, T.-T.5
Faulkner, D.J.6
Peterson, M.R.7
-
52
-
-
33845279007
-
The thermal, aliphatic claisen rearrangement
-
Ziegler, F. The thermal, aliphatic Claisen rearrangement. Chem. Rev., 1988, 88, 1423.
-
(1988)
Chem. Rev
, vol.88
, pp. 1423
-
-
Ziegler, F.1
-
53
-
-
70449632674
-
Total syntheses of all stereoisomers of phenatic acid b
-
Fernandes, R. A.; Chowdhury, A. K. Total syntheses of all stereoisomers of phenatic acid B. J. Org. Chem., 2009, 74, 8826.
-
(2009)
J. Org. Chem
, vol.74
, pp. 8826
-
-
Fernandes, R.A.1
Chowdhury, A.K.2
-
54
-
-
58349086519
-
Chiral vicinal diols as platforms for separable diastereomers in johnson-claisen rearrangement: A new short route to ()-nor-canadensolide ()-canadensolide and ()-sporothriolide
-
Fernandes, R. A.; Ingle, A. B. Chiral vicinal diols as platforms for separable diastereomers in Johnson-Claisen rearrangement: A new short route to ()-nor-canadensolide, ()-canadensolide and ()-sporothriolide. Tetrahedron Lett., 2009, 50, 1122.
-
(2009)
Tetrahedron Lett
, vol.50
, pp. 1122
-
-
Fernandes, R.A.1
Ingle, A.B.2
-
55
-
-
35548984925
-
An efficient synthesis of (-)-posticlure: The sex pheromone of orygia postica
-
Fernandes, R. A. An efficient synthesis of (-)-posticlure: the sex pheromone of Orygia postica. Eur. J. Org. Chem., 2007, 5064.
-
(2007)
Eur. J. Org. Chem
, pp. 5064
-
-
Fernandes, R.A.1
-
56
-
-
84856754621
-
Control of diastereoselectivity in orthoester johnson-claisen rearrangement of tartrate-based allyl alcohol: An efficient synthesis of arundic acid, a potential therapeutic agent for alzheimer's disease
-
Fernandes, R. A.; Ingle, A. B.; Chaudhari, D. Control of diastereoselectivity in orthoester Johnson-Claisen rearrangement of tartrate-based allyl alcohol: An efficient synthesis of arundic acid, a potential therapeutic agent for Alzheimer's disease. Eur. J. Org. Chem., 2012, 1047.
-
(2012)
Eur. J. Org. Chem
, pp. 1047
-
-
Fernandes, R.A.1
Ingle, A.B.2
Chaudhari, D.3
-
57
-
-
80051747006
-
Highly enantioselective-Alkylation of aldehydes with 1, 3-benzodithiolylium tetrafluoroborate: A formal organocatalytic-Alkylation of aldehydes by the carbenium ion. Angew
-
Gualandi, A.; Emer, E.; Capdevila, M. G.; Cozzi, P. G. Highly enantioselective-Alkylation of aldehydes with 1,3-benzodithiolylium tetrafluoroborate: A formal organocatalytic-alkylation of aldehydes by the carbenium ion. Angew. Chem. Int. Ed., 2011, 50, 7842.
-
(2011)
Chem. Int. Ed
, vol.50
, pp. 7842
-
-
Gualandi, A.1
Emer, E.2
Capdevila, M.G.3
Cozzi, P.G.4
-
58
-
-
84857544234
-
Direct regiospecific and highly enantioselective intermolecular- Allylicalkylation of aldehydes by a combination of transition-metal and chiral amine catalysts
-
Afewerki, S.; Ibrahem, I.; Rydfjord, J.; Breistein, P.; Córdova, A. Direct regiospecific and highly enantioselective intermolecular- allylicalkylation of aldehydes by a combination of transition-metal and chiral amine catalysts. Chem. Eur. J., 2012, 18, 2972.
-
(2012)
Chem. Eur. J
, vol.18
, pp. 2972
-
-
Afewerki, S.1
Ibrahem, I.2
Rydfjord, J.3
Breistein, P.4
Córdova, A.5
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