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Volumn 62, Issue 3, 2003, Pages 280-291

Increased vulnerability to focal ischemic brain injury in human apolipoprotein E4 knock-in mice

Author keywords

Apolipoprotein E; Focal cerebral ischemia; Knock in mouse

Indexed keywords

APOLIPOPROTEIN E4;

EID: 0037339577     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnen/62.3.280     Document Type: Article
Times cited : (18)

References (45)
  • 1
    • 0024299370 scopus 로고
    • Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
    • Mahley RW. Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology. Science 1988;240:622-30
    • (1988) Science , vol.240 , pp. 622-630
    • Mahley, R.W.1
  • 2
    • 0028172930 scopus 로고
    • Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease
    • Poirier J. Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease. Trends Neurosci 1994;17:525-30
    • (1994) Trends Neurosci , vol.17 , pp. 525-530
    • Poirier, J.1
  • 3
    • 0004982358 scopus 로고
    • Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets
    • Elshourbagy NA, Liao WS, Mahley RW, Taylor JM. Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets. Proc Natl Acad Sci U S A 1985;82:203-7
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 203-207
    • Elshourbagy, N.A.1    Liao, W.S.2    Mahley, R.W.3    Taylor, J.M.4
  • 4
    • 0022350033 scopus 로고
    • Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system
    • Boyles JK, Pitas RE, Wilson E, Mahley RW, Taylor JM. Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. J Clin Invest 1985;76:1501-13
    • (1985) J Clin Invest , vol.76 , pp. 1501-1513
    • Boyles, J.K.1    Pitas, R.E.2    Wilson, E.3    Mahley, R.W.4    Taylor, J.M.5
  • 5
    • 0023080585 scopus 로고
    • Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins
    • Pitas RE, Boyles JK, Lee SH, Foss D, Mahley RW. Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins. Biochim Biophys Acta 1987;917:148-61
    • (1987) Biochim Biophys Acta , vol.917 , pp. 148-161
    • Pitas, R.E.1    Boyles, J.K.2    Lee, S.H.3    Foss, D.4    Mahley, R.W.5
  • 6
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
    • Corder EH, Saunders AM, Strittmatter WJ, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993;261:921-23
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 7
    • 0027407565 scopus 로고
    • Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
    • Strittmatter WJ, Saunders AM. Schmechel D, et al. Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A 1993;90:1977-81
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 1977-1981
    • Strittmatter, W.J.1    Saunders, A.M.2    Schmechel, D.3
  • 8
    • 0029161810 scopus 로고
    • ApoE genotype and survival from intracerebral haemorrhage
    • Alberts MJ, Graffagnino C, McClenny C, et al. ApoE genotype and survival from intracerebral haemorrhage. Lancet 1995;346:575
    • (1995) Lancet , vol.346 , pp. 575
    • Alberts, M.J.1    Graffagnino, C.2    McClenny, C.3
  • 9
    • 0028986690 scopus 로고
    • Apolipoprolein E ε4 allele is associated with deposition of amyloid β-protein following head injury
    • Nicoll JA, Roberts GW, Graham DI. Apolipoprolein E ε4 allele is associated with deposition of amyloid β-protein following head injury. Nat Med 1995;1:135-37
    • (1995) Nat Med , vol.1 , pp. 135-137
    • Nicoll, J.A.1    Roberts, G.W.2    Graham, D.I.3
  • 10
    • 0029077730 scopus 로고
    • Head injury, amyloid β and Alzheimer's disease
    • Roses AD, Saunders A. Head injury, amyloid β and Alzheimer's disease. Nat Med 1995;1:603-4
    • (1995) Nat Med , vol.1 , pp. 603-604
    • Roses, A.D.1    Saunders, A.2
  • 11
    • 0030770308 scopus 로고    scopus 로고
    • Association of apolipoprotein E polymorphism with outcome after head injury
    • Teasdale GM, Nicoll JA, Murray G, Fiddes M. Association of apolipoprotein E polymorphism with outcome after head injury. Lancet 1997;350:1069-71
    • (1997) Lancet , vol.350 , pp. 1069-1071
    • Teasdale, G.M.1    Nicoll, J.A.2    Murray, G.3    Fiddes, M.4
  • 12
    • 0030612497 scopus 로고    scopus 로고
    • Apolipoprotein E ε4 associated with chronic traumatic brain injury in boxing
    • Jordan BD, Relkin NR, Ravdin LD, Jacobs AR, Bennett A, Gandy S. Apolipoprotein E ε4 associated with chronic traumatic brain injury in boxing. JAMA 1997;278:136-40
    • (1997) JAMA , vol.278 , pp. 136-140
    • Jordan, B.D.1    Relkin, N.R.2    Ravdin, L.D.3    Jacobs, A.R.4    Bennett, A.5    Gandy, S.6
  • 13
    • 0034075368 scopus 로고    scopus 로고
    • Age-dependent association of apolipoprotein E genotypes with stroke subtypes in a Japanese rural population
    • Kokubo Y, Chowdhury AH, Date C, Yokoyama T. Sobue H, Tanaka H. Age-dependent association of apolipoprotein E genotypes with stroke subtypes in a Japanese rural population. Stroke 2000;31:1299-306
    • (2000) Stroke , vol.31 , pp. 1299-1306
    • Kokubo, Y.1    Chowdhury, A.H.2    Date, C.3    Yokoyama, T.4    Sobue, H.5    Tanaka, H.6
  • 14
    • 0036163194 scopus 로고    scopus 로고
    • Apolipoprotein E genotype and outcome in aneurysmal subarachnoid hemorrhage
    • Leung CH, Poon WS, Yu LM, Wong GK, Ng HK. Apolipoprotein E genotype and outcome in aneurysmal subarachnoid hemorrhage. Stroke 2002;33:548-52
    • (2002) Stroke , vol.33 , pp. 548-552
    • Leung, C.H.1    Poon, W.S.2    Yu, L.M.3    Wong, G.K.4    Ng, H.K.5
  • 15
    • 0032874367 scopus 로고    scopus 로고
    • APOE genotype as a risk factor for ischemic cerebrovascular disease: A meta-analysis
    • McCarron MO, Delong D, Alberts MJ. APOE genotype as a risk factor for ischemic cerebrovascular disease: A meta-analysis. Neurology 1999;53:1308-11
    • (1999) Neurology , vol.53 , pp. 1308-1311
    • McCarron, M.O.1    Delong, D.2    Alberts, M.J.3
  • 16
    • 0001043445 scopus 로고    scopus 로고
    • Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice
    • Sheng H, Laskowitz DT, Bennett E, et al. Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice. J Cereb Blood Flow Metab 1998;18:361-66
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 361-366
    • Sheng, H.1    Laskowitz, D.T.2    Bennett, E.3
  • 17
    • 0033564771 scopus 로고    scopus 로고
    • Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: Isoform-specific effects on neurodegeneration
    • Buttini M, Orth M, Bellosta S. et al. Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: Isoform-specific effects on neurodegeneration. J Neurosci 1999;19:4867-80
    • (1999) J Neurosci , vol.19 , pp. 4867-4880
    • Buttini, M.1    Orth, M.2    Bellosta, S.3
  • 18
    • 0034055035 scopus 로고    scopus 로고
    • Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease
    • Buttini M, Akeefe H, Lin C, et al. Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease. Neuroscience 2000;97:207-10
    • (2000) Neuroscience , vol.97 , pp. 207-210
    • Buttini, M.1    Akeefe, H.2    Lin, C.3
  • 19
    • 0032708306 scopus 로고    scopus 로고
    • Human apolipoprotein E isoform-specific differences in neuronal sprouting in organotypic hippocampal culture
    • Teter B, Xu PT, Gilbert JR, Roses AD, Galasko D, Cole GM. Human apolipoprotein E isoform-specific differences in neuronal sprouting in organotypic hippocampal culture. J Neurochem 1999;73:2613-16
    • (1999) J Neurochem , vol.73 , pp. 2613-2616
    • Teter, B.1    Xu, P.T.2    Gilbert, J.R.3    Roses, A.D.4    Galasko, D.5    Cole, G.M.6
  • 20
    • 0034510158 scopus 로고    scopus 로고
    • Increased neuronal damage and apoE immunoreactivity in human apolipoprotein E, E4 isoform-specific, transgenic mice after global cerebral ischaemia
    • Horsburgh K, McCulloch J, Nilsen M, Roses AD, Nicoll JA. Increased neuronal damage and apoE immunoreactivity in human apolipoprotein E, E4 isoform-specific, transgenic mice after global cerebral ischaemia. Eur J Neurosci 2000;12:4309-17
    • (2000) Eur J Neurosci , vol.12 , pp. 4309-4317
    • Horsburgh, K.1    McCulloch, J.2    Nilsen, M.3    Roses, A.D.4    Nicoll, J.A.5
  • 21
    • 0034864642 scopus 로고    scopus 로고
    • Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of en?orhinal cortex lesion
    • White F, Nicoll JA, Roses AD, Horsburgh K. Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of en?orhinal cortex lesion. Neurobiol Dis 2001;8:611-25
    • (2001) Neurobiol Dis , vol.8 , pp. 611-625
    • White, F.1    Nicoll, J.A.2    Roses, A.D.3    Horsburgh, K.4
  • 22
    • 0033968648 scopus 로고    scopus 로고
    • Apolipoprotein E4 exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture
    • Michikawa M, Fan QW, Isobe I, Yanagisawa K. Apolipoprotein E4 exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture. J Neurochem 2000;74:1008-16
    • (2000) J Neurochem , vol.74 , pp. 1008-1016
    • Michikawa, M.1    Fan, Q.W.2    Isobe, I.3    Yanagisawa, K.4
  • 25
    • 0028822219 scopus 로고
    • Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line
    • Holtzman DM, Pitas RE, Kilbridge J, et al. Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line. Proc Natl Acad Sci U S A 1995;92:9480-84
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 9480-9484
    • Holtzman, D.M.1    Pitas, R.E.2    Kilbridge, J.3
  • 26
    • 0034639675 scopus 로고    scopus 로고
    • Altered cholesterol metabolism in human apolipoprotein E4 knock-in mice
    • Hamanaka H, Katoh-Fukui Y, Suzuki K, et al. Altered cholesterol metabolism in human apolipoprotein E4 knock-in mice. Hum Mol Genet 2000;9:353-61
    • (2000) Hum Mol Genet , vol.9 , pp. 353-361
    • Hamanaka, H.1    Katoh-Fukui, Y.2    Suzuki, K.3
  • 27
    • 0026052370 scopus 로고
    • Detection of human apolipoprotein E3, E2, and E4 genotypes by an allele-specific oligonucleotide-primed polymerase chain reaction assay: Development and validation
    • Green EK, Bain SC, Day PJ, et al. Detection of human apolipoprotein E3, E2, and E4 genotypes by an allele-specific oligonucleotide-primed polymerase chain reaction assay: Development and validation. Clin Chem 1991;37:1263-68
    • (1991) Clin Chem , vol.37 , pp. 1263-1268
    • Green, E.K.1    Bain, S.C.2    Day, P.J.3
  • 28
    • 0035823496 scopus 로고    scopus 로고
    • Inhibition of protein phosphatase 2A overrides tau protein kinase 1/glycogen synthase kinase 3β and cyctin-dependent kinase 5 inhibition and results in tau hyperphosphorylation in the hippocampus of starved mouse
    • Planel E, Yasutake K, Fujita SC, Ishiguro K. Inhibition of protein phosphatase 2A overrides tau protein kinase 1/glycogen synthase kinase 3β and cyctin-dependent kinase 5 inhibition and results in tau hyperphosphorylation in the hippocampus of starved mouse. J Biol Chem 2001;276:34298-306
    • (2001) J Biol Chem , vol.276 , pp. 34298-34306
    • Planel, E.1    Yasutake, K.2    Fujita, S.C.3    Ishiguro, K.4
  • 29
    • 0032705473 scopus 로고    scopus 로고
    • Apolipoprotein E is found in astrocytes but not microglia in the normal mouse brain
    • Fujita SC, Sakuta K, Tsuchiya R, Hamanaka H. Apolipoprotein E is found in astrocytes but not microglia in the normal mouse brain. Neurosci Res 1999;35:123-33
    • (1999) Neurosci Res , vol.35 , pp. 123-133
    • Fujita, S.C.1    Sakuta, K.2    Tsuchiya, R.3    Hamanaka, H.4
  • 30
    • 0032400783 scopus 로고    scopus 로고
    • Attenuation of focal ischemic brain injury in mice deficient in the ε1 (NR2A) subunit of NMDA receptor
    • Morikawa E, Mori H, Kiyama Y, Mishina M, Asano T, Kirino T. Attenuation of focal ischemic brain injury in mice deficient in the ε1 (NR2A) subunit of NMDA receptor. J Neurosci 1998;18:9727-32
    • (1998) J Neurosci , vol.18 , pp. 9727-9732
    • Morikawa, E.1    Mori, H.2    Kiyama, Y.3    Mishina, M.4    Asano, T.5    Kirino, T.6
  • 31
    • 0033596566 scopus 로고    scopus 로고
    • Intraluminal increase of superoxide anion following transient focal cerebral ischemia in rats
    • Mori T, Asano T, Matsui T, et al. Intraluminal increase of superoxide anion following transient focal cerebral ischemia in rats. Brain Res 1999;816:350-57
    • (1999) Brain Res , vol.816 , pp. 350-357
    • Mori, T.1    Asano, T.2    Matsui, T.3
  • 32
    • 0034013868 scopus 로고    scopus 로고
    • Possible role of the superoxide anion in the development of neuronal tolerance following ischemic preconditioning in rats
    • Mori T, Muramatsu H, Matsui T, McKee A, Asano T. Possible role of the superoxide anion in the development of neuronal tolerance following ischemic preconditioning in rats. Neuropathol Appl Neurobiol 2000;26:31-40
    • (2000) Neuropathol Appl Neurobiol , vol.26 , pp. 31-40
    • Mori, T.1    Muramatsu, H.2    Matsui, T.3    McKee, A.4    Asano, T.5
  • 33
    • 0031002145 scopus 로고    scopus 로고
    • C57BL/6 strain is most susceptible to cerebral ischemia following bilateral common carotid occlusion among seven mouse strains: Selective neuronal death in the murine transient forebrain ischemia
    • Yang G, Kitagawa K. Matsushita K, et al. C57BL/6 strain is most susceptible to cerebral ischemia following bilateral common carotid occlusion among seven mouse strains: Selective neuronal death in the murine transient forebrain ischemia. Brain Res 1997;752:209-18
    • (1997) Brain Res , vol.752 , pp. 209-218
    • Yang, G.1    Kitagawa, K.2    Matsushita, K.3
  • 34
    • 0032491512 scopus 로고    scopus 로고
    • Isoform-specific vasoconstriction induced by apolipoprotein E and modulation of this effect by Alzheimer's β-amyloid peptide
    • Paris D, Town T, Parker TA, Humphrey J, Mullan M. Isoform-specific vasoconstriction induced by apolipoprotein E and modulation of this effect by Alzheimer's β-amyloid peptide. Neurosci Lett 1998;256:73-76
    • (1998) Neurosci Lett , vol.256 , pp. 73-76
    • Paris, D.1    Town, T.2    Parker, T.A.3    Humphrey, J.4    Mullan, M.5
  • 35
    • 0034018025 scopus 로고    scopus 로고
    • Intraventricular infusion of apolipoprotein E ameliorates acute neuronal damage after global cerebral ischemia in mice
    • Horsburgh K, McCulloch J, Nilsen M, et al. Intraventricular infusion of apolipoprotein E ameliorates acute neuronal damage after global cerebral ischemia in mice. J Cereb Blood Flow Metab 2000;20:458-62
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 458-462
    • Horsburgh, K.1    McCulloch, J.2    Nilsen, M.3
  • 36
    • 0036259904 scopus 로고    scopus 로고
    • Astrocytic activation and delayed infarct expansion following permanent focal ischemia in rats. Part I: Enhanced astrocytic synthesis of S-100β in the periinfarct area precedes the occurrence of delayed infarct expansion
    • Matsui T, Mori T, Tateishi N, et al. Astrocytic activation and delayed infarct expansion following permanent focal ischemia in rats. Part I: Enhanced astrocytic synthesis of S-100β in the periinfarct area precedes the occurrence of delayed infarct expansion. J Cereb Blood Flow Metab 2002;22:711-22
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 711-722
    • Matsui, T.1    Mori, T.2    Tateishi, N.3
  • 37
    • 0027982679 scopus 로고
    • Viability thresholds and the penumbra of focal ischemia
    • Hossmann KA. Viability thresholds and the penumbra of focal ischemia. Ann Neurol 1994;36:557-65
    • (1994) Ann Neurol , vol.36 , pp. 557-565
    • Hossmann, K.A.1
  • 38
    • 0028000627 scopus 로고
    • Brain microvessels: Factors altering their patency after the occlusion of a middle cerebral artery (Wistar rat)
    • Garcia JH, Liu K-F, Yoshida Y, Chen S, Lian J. Brain microvessels: Factors altering their patency after the occlusion of a middle cerebral artery (Wistar rat). Am J Pathol 1994;145:728-40
    • (1994) Am J Pathol , vol.145 , pp. 728-740
    • Garcia, J.H.1    Liu, K.-F.2    Yoshida, Y.3    Chen, S.4    Lian, J.5
  • 39
    • 0033027714 scopus 로고    scopus 로고
    • Is the cell death pathway triggered by the mitochondrion or the endoplasmic reticulum?
    • Siesjö BK, Hu B, Kristiàn T. Is the cell death pathway triggered by the mitochondrion or the endoplasmic reticulum? J Cereb Blood Flow Metab 1999;19:19-26
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 19-26
    • Siesjö, B.K.1    Hu, B.2    Kristiàn, T.3
  • 40
    • 0028802605 scopus 로고
    • Increased amyloid protein precursor and apolipoprotein E immunoreactivity in the selectively vulnerable hippocampus following transient forebrain ischemia in gerbils
    • Hall ED, Oostveen JA, Dunn E, Carter DB. Increased amyloid protein precursor and apolipoprotein E immunoreactivity in the selectively vulnerable hippocampus following transient forebrain ischemia in gerbils. Exp Neurol 1995;135:17-27
    • (1995) Exp Neurol , vol.135 , pp. 17-27
    • Hall, E.D.1    Oostveen, J.A.2    Dunn, E.3    Carter, D.B.4
  • 41
    • 0023280054 scopus 로고
    • Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B. E (LDL) receptors in the brain
    • Pitas RE, Boyles JK, Lee SH, Hui D, Weisgraber KH. Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B. E (LDL) receptors in the brain. J Biol Chem 1987;262:14352-60
    • (1987) J Biol Chem , vol.262 , pp. 14352-14360
    • Pitas, R.E.1    Boyles, J.K.2    Lee, S.H.3    Hui, D.4    Weisgraber, K.H.5
  • 43
    • 0037119427 scopus 로고    scopus 로고
    • Apolipoprotein E (apoE) isoform-dependent lipid release from astrocytes prepared from human-apoE3- and apoE4-knock-in mice
    • Gong JS, Kobayashi M, Hayashi H, et al. Apolipoprotein E (apoE) isoform-dependent lipid release from astrocytes prepared from human-apoE3- and apoE4-knock-in mice. J Biol Chem 2002;277:29919-26
    • (2002) J Biol Chem , vol.277 , pp. 29919-29926
    • Gong, J.S.1    Kobayashi, M.2    Hayashi, H.3
  • 44
    • 0027397693 scopus 로고
    • Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat
    • Garcia JH, Yoshida Y, Chen H, et al. Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat. Am J Pathol 1993;142:623-35
    • (1993) Am J Pathol , vol.142 , pp. 623-635
    • Garcia, J.H.1    Yoshida, Y.2    Chen, H.3
  • 45
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • Lipton P. Ischemic cell death in brain neurons. Physiol Rev 1999;79:1431-1568
    • (1999) Physiol Rev , vol.79 , pp. 1431-1568
    • Lipton, P.1


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