Rationale and design of the 'MITOCARE' study: A phase II, multicenter, randomized, double-blind, placebo-controlled study to assess the safety and efficacy of TRO40303 for the reduction of reperfusion injury in patients undergoing percutaneous coronary intervention for acute myocardial infarction

Cardiology (Switzerland)

Volumn 123, Issue 4, 2012, Pages 201-207

  Atar, Dan ^a   Abitbol, Jean Louis ^b   Arheden, Hakan ^c   Berdeaux, Alain ^d   Bonnet, Jean Louis ^e   Carlsson, Marcus ^c   Clemmensen, Peter ^f   Cuvier, Valérie ^b   Danchin, Nicolas ^g   Dubois Randé, Jean Luc ^h   Engblom, Henrik ^c   Erlinge, David ⁱ   Firat, Hü Seyin ^j   Jensen, Svend Eggert ^k   Halvorsen, Sigrun ^l   Hansen, Henrik Steen ^m   Heiberg, Einar ^c   Larsen, Alf Inge ⁿ   Le Corvoisier, Philippe ^h   Longlade, Pascal ^b   Nordrehaug, Jan Erik ^o   Perez, Carole ^b   Pruss, Rebecca ^b   Sonou, Gilles ^p   Schaller, Sophie ^b   Tuseth, Vegard ^o   Vicaut, Eric ^q   more..

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^b Trophos SA   (France)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

^d UNIVERSITÉ PARIS EST CRÉTEIL   (France)

^e TIMONE HOSPITAL   (France)

^f International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

^g HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^h HENRI MONDOR HOSPITAL   (France)

ⁱ LUND UNIVERSITY   (Sweden)

^j Firalis SAS   (France)

^k Aalborg Regional Laboratory   (Denmark)

^l OSLO UNIVERSITY HOSPITAL   (Norway)

^m ODENSE UNIVERSITY HOSPITAL   (Denmark)

ⁿ STAVANGER UNIVERSITY HOSPITAL   (Norway)

^o UNIVERSITY OF BERGEN   (Norway)

^p Mobile Health   (France)

^q Lariboisiae Hospital   (France)

more..

Author keywords

Acute myocardial infarction; EU FP7 grant; Percutaneous coronary intervention; Reperfusion injury; TRO40303

Indexed keywords

CARRIER PROTEIN; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; TRO40303; UNCLASSIFIED DRUG;

ACUTE HEART INFARCTION; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR MAGNETIC RESONANCE; DRUG EFFICACY; DRUG SAFETY; HEART MUSCLE ISCHEMIA; HUMAN; INTENTION TO TREAT ANALYSIS; MORTALITY; MULTICENTER STUDY (TOPIC); MUSCLE ISCHEMIA; PERCUTANEOUS CORONARY INTERVENTION; PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REPERFUSION INJURY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STUDY DESIGN;

EID: 84872077959     PISSN: 00086312     EISSN: 14219751     Source Type: Journal    
DOI: 10.1159/000342981     Document Type: Article

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