메뉴 건너뛰기




Volumn 304, Issue 6, 2013, Pages

Pirfenidone inhibits macrophage infiltration in 5/6 nephrectomized rats

Author keywords

Inflammation; Macrophage; Pirfenidone; Renal fibrosis

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ARGINASE 1; BETA N ACETYLHEXOSAMINIDASE; C REACTIVE PROTEIN; CALVASCULIN; CD163 ANTIGEN; CD86 ANTIGEN; CHEMOKINE RECEPTOR CCR7; CHLORDANE; CONNECTIVE TISSUE GROWTH FACTOR; DECTIN 1; FIBRONECTIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; PIRFENIDONE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; ACETYLGLUCOSAMINIDASE; BIOLOGICAL MARKER; CCL2 PROTEIN, RAT; NONSTEROID ANTIINFLAMMATORY AGENT; PYRIDONE DERIVATIVE;

EID: 84877929064     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00507.2012     Document Type: Article
Times cited : (56)

References (42)
  • 1
    • 80054728443 scopus 로고    scopus 로고
    • Renal microenvironments and macrophage pheno-types determine progression or resolution of renal inflammation and fibrosis
    • Anders HJ, Ryu M. Renal microenvironments and macrophage pheno-types determine progression or resolution of renal inflammation and fibrosis. Kidney Int 80: 915-925, 2011.
    • (2011) Kidney Int , vol.80 , pp. 915-925
    • Anders, H.J.1    Ryu, M.2
  • 4
    • 34548834734 scopus 로고    scopus 로고
    • Pirfenidone slows renal function decline in patients with focal segmental glomerulo-sclerosis
    • Cho ME, Smith DC, Branton MH, Penzak SR, Kopp JB. Pirfenidone slows renal function decline in patients with focal segmental glomerulo-sclerosis. Clin J Am Soc Nephrol 2: 906-913, 2007.
    • (2007) Clin J Am Soc Nephrol , vol.2 , pp. 906-913
    • Cho, M.E.1    Smith, D.C.2    Branton, M.H.3    Penzak, S.R.4    Kopp, J.B.5
  • 6
    • 79959379095 scopus 로고    scopus 로고
    • Repertoire of microglial and macrophage responses after spinal cord injury
    • David S, Kroner A. Repertoire of microglial and macrophage responses after spinal cord injury. Nat Rev Neurosci 12: 388-399, 2011.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 388-399
    • David, S.1    Kroner, A.2
  • 8
    • 79959758089 scopus 로고    scopus 로고
    • C-fms blockade reverses glomerular macro-phage infiltration and halts development of crescentic anti-GBM glomer-ulonephritis in the rat
    • Han Y, Ma FY, Tesch GH. C-fms blockade reverses glomerular macro-phage infiltration and halts development of crescentic anti-GBM glomer-ulonephritis in the rat. Lab Invest 91: 978-991, 2011.
    • (2011) Lab Invest , vol.91 , pp. 978-991
    • Han, Y.1    Ma, F.Y.2    Tesch, G.H.3
  • 10
    • 0035576207 scopus 로고    scopus 로고
    • Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: Granulomatous pathology is shaped by the pattern of L-arginine metabolism
    • Hesse M, Modolell M, La Flamme AC, Schito M, Fuentes JM, Cheever AW, Pearce EJ, Wynn TA. Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism. J Immunol 167: 6533-6544, 2001.
    • (2001) J Immunol , vol.167 , pp. 6533-6544
    • Hesse, M.1    Modolell, M.2    la Flamme, A.C.3    Schito, M.4    Fuentes, J.M.5    Cheever, A.W.6    Pearce, E.J.7    Wynn, T.A.8
  • 11
    • 10944240449 scopus 로고    scopus 로고
    • Quantitative mor-phometry of lupus nephritis: The significance of collagen, tubular space, and inflammatory infiltrate
    • Hunter MG, Hurwitz S, Bellamy CO, Duffield JS. Quantitative mor-phometry of lupus nephritis: the significance of collagen, tubular space, and inflammatory infiltrate. Kidney Int 67: 94-102, 2005.
    • (2005) Kidney Int , vol.67 , pp. 94-102
    • Hunter, M.G.1    Hurwitz, S.2    Bellamy, C.O.3    Duffield, J.S.4
  • 12
    • 0033923129 scopus 로고    scopus 로고
    • Anti-inflammatory effect of pirfenidone in the bleomycin-hamster model of lung inflammation
    • Iyer SN, Hyde DM, Girl SN. Anti-inflammatory effect of pirfenidone in the bleomycin-hamster model of lung inflammation. Inflammation 24: 477-491, 2000.
    • (2000) Inflammation , vol.24 , pp. 477-491
    • Iyer, S.N.1    Hyde, D.M.2    Girl, S.N.3
  • 14
    • 13444271063 scopus 로고    scopus 로고
    • Pirfenidone and candesartan ameliorate morphological damage in mild chronic anti-GBM nephritis in rats
    • Leh S, Vaagnes Ø, Margolin SB, Iversen BM, Forslund T. Pirfenidone and candesartan ameliorate morphological damage in mild chronic anti-GBM nephritis in rats. Nephrol Dial Transplant 20: 71-82, 2005.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 71-82
    • Leh, S.1    Vaagnes, Ø.2    Margolin, S.B.3    Iversen, B.M.4    Forslund, T.5
  • 15
    • 79954550543 scopus 로고    scopus 로고
    • Monocytes induce proximal tubular epithelial-mesenchymal transition through NF-kappa B dependent upregulation of ICAM-1
    • Li Q, Liu BC, Lv LL, Ma KL, Zhang XL, Phillips AO. Monocytes induce proximal tubular epithelial-mesenchymal transition through NF-kappa B dependent upregulation of ICAM-1. J Cell Biochem 112: 1585- 1592, 2011.
    • (2011) J Cell Biochem , vol.112 , pp. 1585-1592
    • Li, Q.1    Liu, B.C.2    Lv, L.L.3    Ma, K.L.4    Zhang, X.L.5    Phillips, A.O.6
  • 16
    • 24644510860 scopus 로고    scopus 로고
    • Pirfenidone inhibits inflammatory responses and ameliorates allograft injury in a rat lung transplant model
    • Liu H, Drew P, Cheng Y, Visner GA. Pirfenidone inhibits inflammatory responses and ameliorates allograft injury in a rat lung transplant model. J Thorac Cardiovasc Surg 130: 852-858, 2005.
    • (2005) J Thorac Cardiovasc Surg , vol.130 , pp. 852-858
    • Liu, H.1    Drew, P.2    Cheng, Y.3    Visner, G.A.4
  • 17
    • 0041427760 scopus 로고    scopus 로고
    • Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion
    • Lucas M, Stuart LM, Savill J, Lacy-Hulbert A. Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion. J Immunol 171: 2610-2615, 2003.
    • (2003) J Immunol , vol.171 , pp. 2610-2615
    • Lucas, M.1    Stuart, L.M.2    Savill, J.3    Lacy-Hulbert, A.4
  • 21
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23: 549-555, 2002.
    • (2002) Trends Immunol , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 24
    • 79952120601 scopus 로고    scopus 로고
    • Monitoring of inflammation in patients on dialysis: Forewarned is forearmed
    • Meuwese CL, Stenvinkel P, Dekker FW, Carrero JJ. Monitoring of inflammation in patients on dialysis: forewarned is forearmed. Nat Rev Nephrol 7: 166-176, 2011.
    • (2011) Nat Rev Nephrol , vol.7 , pp. 166-176
    • Meuwese, C.L.1    Stenvinkel, P.2    Dekker, F.W.3    Carrero, J.J.4
  • 25
    • 0037310024 scopus 로고    scopus 로고
    • The many faces of macrophage activation
    • Mosser DM. The many faces of macrophage activation. J Leukoc Biol 73: 209-212, 2003.
    • (2003) J Leukoc Biol , vol.73 , pp. 209-212
    • Mosser, D.M.1
  • 26
    • 84862268833 scopus 로고    scopus 로고
    • Influence of irbesartan on the urinary excretion of cytokines in patients with chronic kidney disease
    • Ni J, Huang HQ, Lü LL, Zheng M, Liu BC. Influence of irbesartan on the urinary excretion of cytokines in patients with chronic kidney disease. Chin Med J (Engl) 125: 1147-1152, 2012.
    • (2012) Chin Med J (Engl) , vol.125 , pp. 1147-1152
    • Ni, J.1    Huang, H.Q.2    Lü, L.L.3    Zheng, M.4    Liu, B.C.5
  • 28
    • 48149113955 scopus 로고    scopus 로고
    • Antifibrotic action of pirfenidone and prednisolone: Different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis
    • Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A. Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis. Eur J Pharmacol 590: 400-408, 2008.
    • (2008) Eur J Pharmacol , vol.590 , pp. 400-408
    • Oku, H.1    Shimizu, T.2    Kawabata, T.3    Nagira, M.4    Hikita, I.5    Ueyama, A.6    Matsushima, S.7    Torii, M.8    Arimura, A.9
  • 29
    • 84862241956 scopus 로고    scopus 로고
    • Macrophage subpopulations in systemic lupus ery-thematosus
    • Orme J, Mohan C. Macrophage subpopulations in systemic lupus ery-thematosus. Discov Med 13: 151-158, 2012.
    • (2012) Discov Med , vol.13 , pp. 151-158
    • Orme, J.1    Mohan, C.2
  • 31
    • 2342453164 scopus 로고    scopus 로고
    • Increased oxidative stress and apoptosis in acute puromycin aminonucleoside ne-phrosis
    • Rincon J, Romero M, Viera N, Pedreañez A, Mosquera J. Increased oxidative stress and apoptosis in acute puromycin aminonucleoside ne-phrosis. Int J Exp Pathol 85: 25-33, 2004.
    • (2004) Int J Exp Pathol , vol.85 , pp. 25-33
    • Rincon, J.1    Romero, M.2    Viera, N.3    Pedreañez, A.4    Mosquera, J.5
  • 32
    • 67349131293 scopus 로고    scopus 로고
    • Effect of food and antacids on the pharmacokinetics of pirfenidone in older healthy adults
    • Rubino CM, Bhavnani SM, Ambrose PG, Forrest A, Loutit JS. Effect of food and antacids on the pharmacokinetics of pirfenidone in older healthy adults. Pulm Pharmacol Ther 22: 279-285, 2009.
    • (2009) Pulm Pharmacol Ther , vol.22 , pp. 279-285
    • Rubino, C.M.1    Bhavnani, S.M.2    Ambrose, P.G.3    Forrest, A.4    Loutit, J.S.5
  • 33
    • 78650880591 scopus 로고    scopus 로고
    • Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-a-mediated podo-cyte loss
    • Ryu M, Kulkarni OP, Radomska E, Miosge N, Gross O, Anders HJ. Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-a-mediated podo-cyte loss. Kidney Int 79: 189-198, 2011.
    • (2011) Kidney Int , vol.79 , pp. 189-198
    • Ryu, M.1    Kulkarni, O.P.2    Radomska, E.3    Miosge, N.4    Gross, O.5    Anders, H.J.6
  • 38
    • 77953885701 scopus 로고    scopus 로고
    • Targeting the recruitment of monocytes and macrophages in renal disease
    • Vielhauer V, Kulkarni O, Reichel CA, Anders HJ. Targeting the recruitment of monocytes and macrophages in renal disease. Semin Neph-rol 30: 318-333, 2010.
    • (2010) Semin Neph-rol , vol.30 , pp. 318-333
    • Vielhauer, V.1    Kulkarni, O.2    Reichel, C.A.3    Anders, H.J.4
  • 39
    • 69449098808 scopus 로고    scopus 로고
    • Pirfenidone inhibits T-cell activation, proliferation, cyto-kine and chemokine production, and host alloresponses
    • Visner GA, Liu F, Bizargity P, Liu H, Liu K, Yang J, Wang L, Hancock WW. Pirfenidone inhibits T-cell activation, proliferation, cyto-kine and chemokine production, and host alloresponses. Transplantation 88: 330-338, 2009.
    • (2009) Transplantation , vol.88 , pp. 330-338
    • Visner, G.A.1    Liu, F.2    Bizargity, P.3    Liu, H.4    Liu, K.5    Yang, J.6    Wang, L.7    Hancock, W.W.8
  • 40
    • 15544387329 scopus 로고    scopus 로고
    • A double-blind, randomized, controlled study of oral pirfenidone for treatment of secondary progressive multiple sclerosis
    • Walker JE, Giri SN, Margolin SB. A double-blind, randomized, controlled study of oral pirfenidone for treatment of secondary progressive multiple sclerosis. Mult Scler 11: 149-158, 2005.
    • (2005) Mult Scler , vol.11 , pp. 149-158
    • Walker, J.E.1    Giri, S.N.2    Margolin, S.B.3
  • 41
    • 0142210398 scopus 로고    scopus 로고
    • DNA vaccination against specific pathogenic TCRs reduces proteinuria in active Hey-mann nephritis by inducing specific autoantibodies
    • Wu H, Walters G, Knight JF, Alexander SI. DNA vaccination against specific pathogenic TCRs reduces proteinuria in active Hey-mann nephritis by inducing specific autoantibodies. J Immunol 171: 4824-4829, 2003.
    • (2003) J Immunol , vol.171 , pp. 4824-4829
    • Wu, H.1    Walters, G.2    Knight, J.F.3    Alexander, S.I.4
  • 42
    • 79960381007 scopus 로고    scopus 로고
    • Integrating mechanisms of pulmonary fibrosis
    • Wynn TA. Integrating mechanisms of pulmonary fibrosis. J Exp Med 208: 1339-1350, 2011.
    • (2011) J Exp Med , vol.208 , pp. 1339-1350
    • Wynn, T.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.