-
1
-
-
80054728443
-
Renal microenvironments and macrophage pheno-types determine progression or resolution of renal inflammation and fibrosis
-
Anders HJ, Ryu M. Renal microenvironments and macrophage pheno-types determine progression or resolution of renal inflammation and fibrosis. Kidney Int 80: 915-925, 2011.
-
(2011)
Kidney Int
, vol.80
, pp. 915-925
-
-
Anders, H.J.1
Ryu, M.2
-
2
-
-
33750288398
-
A pilot study in patients with established advanced liver fibrosis using pirfenidone
-
Armendáriz-Borunda J, Islas-Carbajal MC, Meza-García E, Rincón AR, Lucano S, Sandoval AS, Salazar A, Berumen J, Alvarez A, Covarrubias A, Aréchiga G, García L. A pilot study in patients with established advanced liver fibrosis using pirfenidone. Gut 55: 1663-1665, 2006.
-
(2006)
Gut
, vol.55
, pp. 1663-1665
-
-
Armendáriz-Borunda, J.1
Islas-Carbajal, M.C.2
Meza-García, E.3
Rincón, A.R.4
Lucano, S.5
Sandoval, A.S.6
Salazar, A.7
Berumen, J.8
Alvarez, A.9
Covarrubias, A.10
Aréchiga, G.11
García, L.12
-
3
-
-
54949155201
-
Macrophage phenotype as a determinant of biologic scaffold remodeling
-
Badylak SF, Valentin JE, Ravindra AK, McCabe GP, Stewart-Akers AM. Macrophage phenotype as a determinant of biologic scaffold remodeling. Tissue Eng 14: 1835-1842, 2008.
-
(2008)
Tissue Eng
, vol.14
, pp. 1835-1842
-
-
Badylak, S.F.1
Valentin, J.E.2
Ravindra, A.K.3
McCabe, G.P.4
Stewart-Akers, A.M.5
-
4
-
-
34548834734
-
Pirfenidone slows renal function decline in patients with focal segmental glomerulo-sclerosis
-
Cho ME, Smith DC, Branton MH, Penzak SR, Kopp JB. Pirfenidone slows renal function decline in patients with focal segmental glomerulo-sclerosis. Clin J Am Soc Nephrol 2: 906-913, 2007.
-
(2007)
Clin J Am Soc Nephrol
, vol.2
, pp. 906-913
-
-
Cho, M.E.1
Smith, D.C.2
Branton, M.H.3
Penzak, S.R.4
Kopp, J.B.5
-
5
-
-
74949115952
-
The phenotype of murine wound macrophages
-
Daley JM, Brancato SK, Thomay AA, Reichner JS, Albina JE. The phenotype of murine wound macrophages. J Leukoc Biol 87: 59-67, 2010.
-
(2010)
J Leukoc Biol
, vol.87
, pp. 59-67
-
-
Daley, J.M.1
Brancato, S.K.2
Thomay, A.A.3
Reichner, J.S.4
Albina, J.E.5
-
6
-
-
79959379095
-
Repertoire of microglial and macrophage responses after spinal cord injury
-
David S, Kroner A. Repertoire of microglial and macrophage responses after spinal cord injury. Nat Rev Neurosci 12: 388-399, 2011.
-
(2011)
Nat Rev Neurosci
, vol.12
, pp. 388-399
-
-
David, S.1
Kroner, A.2
-
7
-
-
77955729725
-
Effect of allopurinol in chronic kidney disease progression and cardiovascular risk
-
Goicoechea M, de Vinuesa SG, Verdalles U, Ruiz-Caro C, Ampuero J, Rincón A, Arroyo D, Luño J. Effect of allopurinol in chronic kidney disease progression and cardiovascular risk. Clin J Am Soc Nephrol 5: 1388-1393, 2010.
-
(2010)
Clin J Am Soc Nephrol
, vol.5
, pp. 1388-1393
-
-
Goicoechea, M.1
de Vinuesa, S.G.2
Verdalles, U.3
Ruiz-Caro, C.4
Ampuero, J.5
Rincón, A.6
Arroyo, D.7
Luño, J.8
-
8
-
-
79959758089
-
C-fms blockade reverses glomerular macro-phage infiltration and halts development of crescentic anti-GBM glomer-ulonephritis in the rat
-
Han Y, Ma FY, Tesch GH. C-fms blockade reverses glomerular macro-phage infiltration and halts development of crescentic anti-GBM glomer-ulonephritis in the rat. Lab Invest 91: 978-991, 2011.
-
(2011)
Lab Invest
, vol.91
, pp. 978-991
-
-
Han, Y.1
Ma, F.Y.2
Tesch, G.H.3
-
9
-
-
39549100788
-
Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis
-
Henderson NC, Mackinnon AC, Farnworth SL, Atkinson KM, Wilkinson T, Dhaliwal K, Hayashi K, Simpson AJ, Rossi AG, Haslett C, Sethi T. Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis. Am J Pathol 172: 288-298, 2008.
-
(2008)
Am J Pathol
, vol.172
, pp. 288-298
-
-
Henderson, N.C.1
Mackinnon, A.C.2
Farnworth, S.L.3
Atkinson, K.M.4
Wilkinson, T.5
Dhaliwal, K.6
Hayashi, K.7
Simpson, A.J.8
Rossi, A.G.9
Haslett, C.10
Sethi, T.11
-
10
-
-
0035576207
-
Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: Granulomatous pathology is shaped by the pattern of L-arginine metabolism
-
Hesse M, Modolell M, La Flamme AC, Schito M, Fuentes JM, Cheever AW, Pearce EJ, Wynn TA. Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism. J Immunol 167: 6533-6544, 2001.
-
(2001)
J Immunol
, vol.167
, pp. 6533-6544
-
-
Hesse, M.1
Modolell, M.2
la Flamme, A.C.3
Schito, M.4
Fuentes, J.M.5
Cheever, A.W.6
Pearce, E.J.7
Wynn, T.A.8
-
11
-
-
10944240449
-
Quantitative mor-phometry of lupus nephritis: The significance of collagen, tubular space, and inflammatory infiltrate
-
Hunter MG, Hurwitz S, Bellamy CO, Duffield JS. Quantitative mor-phometry of lupus nephritis: the significance of collagen, tubular space, and inflammatory infiltrate. Kidney Int 67: 94-102, 2005.
-
(2005)
Kidney Int
, vol.67
, pp. 94-102
-
-
Hunter, M.G.1
Hurwitz, S.2
Bellamy, C.O.3
Duffield, J.S.4
-
12
-
-
0033923129
-
Anti-inflammatory effect of pirfenidone in the bleomycin-hamster model of lung inflammation
-
Iyer SN, Hyde DM, Girl SN. Anti-inflammatory effect of pirfenidone in the bleomycin-hamster model of lung inflammation. Inflammation 24: 477-491, 2000.
-
(2000)
Inflammation
, vol.24
, pp. 477-491
-
-
Iyer, S.N.1
Hyde, D.M.2
Girl, S.N.3
-
13
-
-
0029318974
-
Dietary intake of pirfenidone ameliorates bleomycin-induced lung fibrosis in hamsters
-
Iyer SN, Wild JS, Schiedt MJ, Hyde DM, Margolin SB, Giri SN. Dietary intake of pirfenidone ameliorates bleomycin-induced lung fibrosis in hamsters. J Lab Clin Med 125: 779-785, 1995.
-
(1995)
J Lab Clin Med
, vol.125
, pp. 779-785
-
-
Iyer, S.N.1
Wild, J.S.2
Schiedt, M.J.3
Hyde, D.M.4
Margolin, S.B.5
Giri, S.N.6
-
14
-
-
13444271063
-
Pirfenidone and candesartan ameliorate morphological damage in mild chronic anti-GBM nephritis in rats
-
Leh S, Vaagnes Ø, Margolin SB, Iversen BM, Forslund T. Pirfenidone and candesartan ameliorate morphological damage in mild chronic anti-GBM nephritis in rats. Nephrol Dial Transplant 20: 71-82, 2005.
-
(2005)
Nephrol Dial Transplant
, vol.20
, pp. 71-82
-
-
Leh, S.1
Vaagnes, Ø.2
Margolin, S.B.3
Iversen, B.M.4
Forslund, T.5
-
15
-
-
79954550543
-
Monocytes induce proximal tubular epithelial-mesenchymal transition through NF-kappa B dependent upregulation of ICAM-1
-
Li Q, Liu BC, Lv LL, Ma KL, Zhang XL, Phillips AO. Monocytes induce proximal tubular epithelial-mesenchymal transition through NF-kappa B dependent upregulation of ICAM-1. J Cell Biochem 112: 1585- 1592, 2011.
-
(2011)
J Cell Biochem
, vol.112
, pp. 1585-1592
-
-
Li, Q.1
Liu, B.C.2
Lv, L.L.3
Ma, K.L.4
Zhang, X.L.5
Phillips, A.O.6
-
16
-
-
24644510860
-
Pirfenidone inhibits inflammatory responses and ameliorates allograft injury in a rat lung transplant model
-
Liu H, Drew P, Cheng Y, Visner GA. Pirfenidone inhibits inflammatory responses and ameliorates allograft injury in a rat lung transplant model. J Thorac Cardiovasc Surg 130: 852-858, 2005.
-
(2005)
J Thorac Cardiovasc Surg
, vol.130
, pp. 852-858
-
-
Liu, H.1
Drew, P.2
Cheng, Y.3
Visner, G.A.4
-
17
-
-
0041427760
-
Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion
-
Lucas M, Stuart LM, Savill J, Lacy-Hulbert A. Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion. J Immunol 171: 2610-2615, 2003.
-
(2003)
J Immunol
, vol.171
, pp. 2610-2615
-
-
Lucas, M.1
Stuart, L.M.2
Savill, J.3
Lacy-Hulbert, A.4
-
18
-
-
80052591439
-
The multifaceted role of pirfenidone and its novel targets
-
Macías-Barragán J, Sandoval-Rodríguez A, Navarro-Partida J, Ar-mendáriz-Borunda J. The multifaceted role of pirfenidone and its novel targets. Fibrogenesis Tissue Repair 3: 1-11, 2010.
-
(2010)
Fibrogenesis Tissue Repair
, vol.3
, pp. 1-11
-
-
Macías-Barragán, J.1
Sandoval-Rodríguez, A.2
Navarro-Partida, J.3
Ar-mendáriz-Borunda, J.4
-
19
-
-
79957598147
-
Macrophages in skin injury and repair
-
Mahdavian Delavary B, van der Veer WM, van Egmond M, Niessen FB, Beelen RH. Macrophages in skin injury and repair. Immunobiology 216: 753-762, 2011.
-
(2011)
Immunobiology
, vol.216
, pp. 753-762
-
-
Mahdavian Delavary, B.1
van der Veer, W.M.2
van Egmond, M.3
Niessen, F.B.4
Beelen, R.H.5
-
20
-
-
7644231561
-
The chemokine system in diverse forms of macrophage activation and polarization
-
Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25: 677-686, 2004.
-
(2004)
Trends Immunol
, vol.25
, pp. 677-686
-
-
Mantovani, A.1
Sica, A.2
Sozzani, S.3
Allavena, P.4
Vecchi, A.5
Locati, M.6
-
21
-
-
0036839143
-
Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
-
Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23: 549-555, 2002.
-
(2002)
Trends Immunol
, vol.23
, pp. 549-555
-
-
Mantovani, A.1
Sozzani, S.2
Locati, M.3
Allavena, P.4
Sica, A.5
-
22
-
-
38449102676
-
Macrophage activation and polarization
-
Martinez FO, Sica A, Mantovani A, Locati M. Macrophage activation and polarization. Front Biosci 13: 453-461, 2008.
-
(2008)
Front Biosci
, vol.13
, pp. 453-461
-
-
Martinez, F.O.1
Sica, A.2
Mantovani, A.3
Locati, M.4
-
23
-
-
1642296564
-
Pirfenidone inhibits obliterative airway disease in a murine heterotopic tracheal transplant model
-
Mckane BW, Fernandez F, Narayanan K, Marshbank S, Margolin SB, Jendrisak M, Mohanakumar T. Pirfenidone inhibits obliterative airway disease in a murine heterotopic tracheal transplant model. Trans-platation 77: 664-669, 2004.
-
(2004)
Trans-platation
, vol.77
, pp. 664-669
-
-
McKane, B.W.1
Fernandez, F.2
Narayanan, K.3
Marshbank, S.4
Margolin, S.B.5
Jendrisak, M.6
Mohanakumar, T.7
-
24
-
-
79952120601
-
Monitoring of inflammation in patients on dialysis: Forewarned is forearmed
-
Meuwese CL, Stenvinkel P, Dekker FW, Carrero JJ. Monitoring of inflammation in patients on dialysis: forewarned is forearmed. Nat Rev Nephrol 7: 166-176, 2011.
-
(2011)
Nat Rev Nephrol
, vol.7
, pp. 166-176
-
-
Meuwese, C.L.1
Stenvinkel, P.2
Dekker, F.W.3
Carrero, J.J.4
-
25
-
-
0037310024
-
The many faces of macrophage activation
-
Mosser DM. The many faces of macrophage activation. J Leukoc Biol 73: 209-212, 2003.
-
(2003)
J Leukoc Biol
, vol.73
, pp. 209-212
-
-
Mosser, D.M.1
-
26
-
-
84862268833
-
Influence of irbesartan on the urinary excretion of cytokines in patients with chronic kidney disease
-
Ni J, Huang HQ, Lü LL, Zheng M, Liu BC. Influence of irbesartan on the urinary excretion of cytokines in patients with chronic kidney disease. Chin Med J (Engl) 125: 1147-1152, 2012.
-
(2012)
Chin Med J (Engl)
, vol.125
, pp. 1147-1152
-
-
Ni, J.1
Huang, H.Q.2
Lü, L.L.3
Zheng, M.4
Liu, B.C.5
-
27
-
-
79956341531
-
Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): Two randomised trials
-
CAPACITY Study Group
-
Noble PW, Albera C, Bradford WZ, Bradford WZ, Costabel U, Glassberg MK, Kardatzke D, King TE Jr, Lancaster L, Sahn SA, Szwarcberg J, Valeyre D, du Bois RM; CAPACITY Study Group. Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials. Lancet 377: 1760-1769, 2011.
-
(2011)
Lancet
, vol.377
, pp. 1760-1769
-
-
Noble, P.W.1
Albera, C.2
Bradford, W.Z.3
Bradford, W.Z.4
Costabel, U.5
Glassberg, M.K.6
Kardatzke, D.7
King Jr., T.E.8
Lancaster, L.9
Sahn, S.A.10
Szwarcberg, J.11
Valeyre, D.12
du Bois, R.M.13
-
28
-
-
48149113955
-
Antifibrotic action of pirfenidone and prednisolone: Different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis
-
Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A. Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis. Eur J Pharmacol 590: 400-408, 2008.
-
(2008)
Eur J Pharmacol
, vol.590
, pp. 400-408
-
-
Oku, H.1
Shimizu, T.2
Kawabata, T.3
Nagira, M.4
Hikita, I.5
Ueyama, A.6
Matsushima, S.7
Torii, M.8
Arimura, A.9
-
29
-
-
84862241956
-
Macrophage subpopulations in systemic lupus ery-thematosus
-
Orme J, Mohan C. Macrophage subpopulations in systemic lupus ery-thematosus. Discov Med 13: 151-158, 2012.
-
(2012)
Discov Med
, vol.13
, pp. 151-158
-
-
Orme, J.1
Mohan, C.2
-
30
-
-
68149178848
-
Pirfenidone is renoprotective in diabetic kidney disease
-
RamachandraRao SP, Zhu Y, Ravasi T, McGowan TA, Toh I, Dunn SR, Okada S, Shaw MA, Sharma K. Pirfenidone is renoprotective in diabetic kidney disease. J Am Soc Nephrol 20: 1765-1775, 2009.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1765-1775
-
-
Ramachandrarao, S.P.1
Zhu, Y.2
Ravasi, T.3
McGowan, T.A.4
Toh, I.5
Dunn, S.R.6
Okada, S.7
Shaw, M.A.8
Sharma, K.9
-
31
-
-
2342453164
-
Increased oxidative stress and apoptosis in acute puromycin aminonucleoside ne-phrosis
-
Rincon J, Romero M, Viera N, Pedreañez A, Mosquera J. Increased oxidative stress and apoptosis in acute puromycin aminonucleoside ne-phrosis. Int J Exp Pathol 85: 25-33, 2004.
-
(2004)
Int J Exp Pathol
, vol.85
, pp. 25-33
-
-
Rincon, J.1
Romero, M.2
Viera, N.3
Pedreañez, A.4
Mosquera, J.5
-
32
-
-
67349131293
-
Effect of food and antacids on the pharmacokinetics of pirfenidone in older healthy adults
-
Rubino CM, Bhavnani SM, Ambrose PG, Forrest A, Loutit JS. Effect of food and antacids on the pharmacokinetics of pirfenidone in older healthy adults. Pulm Pharmacol Ther 22: 279-285, 2009.
-
(2009)
Pulm Pharmacol Ther
, vol.22
, pp. 279-285
-
-
Rubino, C.M.1
Bhavnani, S.M.2
Ambrose, P.G.3
Forrest, A.4
Loutit, J.S.5
-
33
-
-
78650880591
-
Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-a-mediated podo-cyte loss
-
Ryu M, Kulkarni OP, Radomska E, Miosge N, Gross O, Anders HJ. Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-a-mediated podo-cyte loss. Kidney Int 79: 189-198, 2011.
-
(2011)
Kidney Int
, vol.79
, pp. 189-198
-
-
Ryu, M.1
Kulkarni, O.P.2
Radomska, E.3
Miosge, N.4
Gross, O.5
Anders, H.J.6
-
34
-
-
79957670746
-
Pirfenidone for diabetic nephropathy
-
Sharma K, Ix JH, Mathew AV, Cho M, Pflueger A, Dunn SR, Francos B, Sharma S, Falkner B, McGowan TA, Donohue M, Ramachandra-rao S, Xu R, Fervenza FC, Kopp JB. Pirfenidone for diabetic nephropathy. J Am Soc Nephrol 22: 1144-1151, 2011.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1144-1151
-
-
Sharma, K.1
Ix, J.H.2
Mathew, A.V.3
Cho, M.4
Pflueger, A.5
Dunn, S.R.6
Francos, B.7
Sharma, S.8
Falkner, B.9
McGowan, T.A.10
Donohue, M.11
Ramachandra-Rao, S.12
Xu, R.13
Fervenza, F.C.14
Kopp, J.B.15
-
35
-
-
0031474029
-
Pirfenidone prevents collagen accumulation in the remnant kidney in rats with partial nephrectomy
-
Shimizu T, Fukagawa M, Kuroda T, Hata S, Iwasaki Y, Nemoto M, Shirai K, Yamauchi S, Margolin SB, Shimizu F, Kurokawa K. Pirfenidone prevents collagen accumulation in the remnant kidney in rats with partial nephrectomy. Kidney Int Suppl 63: S239-243, 1997.
-
(1997)
Kidney Int Suppl
, vol.63
-
-
Shimizu, T.1
Fukagawa, M.2
Kuroda, T.3
Hata, S.4
Iwasaki, Y.5
Nemoto, M.6
Shirai, K.7
Yamauchi, S.8
Margolin, S.B.9
Shimizu, F.10
Kurokawa, K.11
-
36
-
-
74149086684
-
Renoprotective properties of pirfenidone in subtotally nephrectomized rats
-
Takakuta K, Fujimori A, Chikanishi T, Tanokura A, Iwatsuki Y, Yamamoto M, Nakajima H, Okada M, Itoh H. Renoprotective properties of pirfenidone in subtotally nephrectomized rats. Eur J Pharmacol 629: 118-124, 2010.
-
(2010)
Eur J Pharmacol
, vol.629
, pp. 118-124
-
-
Takakuta, K.1
Fujimori, A.2
Chikanishi, T.3
Tanokura, A.4
Iwatsuki, Y.5
Yamamoto, M.6
Nakajima, H.7
Okada, M.8
Itoh, H.9
-
38
-
-
77953885701
-
Targeting the recruitment of monocytes and macrophages in renal disease
-
Vielhauer V, Kulkarni O, Reichel CA, Anders HJ. Targeting the recruitment of monocytes and macrophages in renal disease. Semin Neph-rol 30: 318-333, 2010.
-
(2010)
Semin Neph-rol
, vol.30
, pp. 318-333
-
-
Vielhauer, V.1
Kulkarni, O.2
Reichel, C.A.3
Anders, H.J.4
-
39
-
-
69449098808
-
Pirfenidone inhibits T-cell activation, proliferation, cyto-kine and chemokine production, and host alloresponses
-
Visner GA, Liu F, Bizargity P, Liu H, Liu K, Yang J, Wang L, Hancock WW. Pirfenidone inhibits T-cell activation, proliferation, cyto-kine and chemokine production, and host alloresponses. Transplantation 88: 330-338, 2009.
-
(2009)
Transplantation
, vol.88
, pp. 330-338
-
-
Visner, G.A.1
Liu, F.2
Bizargity, P.3
Liu, H.4
Liu, K.5
Yang, J.6
Wang, L.7
Hancock, W.W.8
-
40
-
-
15544387329
-
A double-blind, randomized, controlled study of oral pirfenidone for treatment of secondary progressive multiple sclerosis
-
Walker JE, Giri SN, Margolin SB. A double-blind, randomized, controlled study of oral pirfenidone for treatment of secondary progressive multiple sclerosis. Mult Scler 11: 149-158, 2005.
-
(2005)
Mult Scler
, vol.11
, pp. 149-158
-
-
Walker, J.E.1
Giri, S.N.2
Margolin, S.B.3
-
41
-
-
0142210398
-
DNA vaccination against specific pathogenic TCRs reduces proteinuria in active Hey-mann nephritis by inducing specific autoantibodies
-
Wu H, Walters G, Knight JF, Alexander SI. DNA vaccination against specific pathogenic TCRs reduces proteinuria in active Hey-mann nephritis by inducing specific autoantibodies. J Immunol 171: 4824-4829, 2003.
-
(2003)
J Immunol
, vol.171
, pp. 4824-4829
-
-
Wu, H.1
Walters, G.2
Knight, J.F.3
Alexander, S.I.4
-
42
-
-
79960381007
-
Integrating mechanisms of pulmonary fibrosis
-
Wynn TA. Integrating mechanisms of pulmonary fibrosis. J Exp Med 208: 1339-1350, 2011.
-
(2011)
J Exp Med
, vol.208
, pp. 1339-1350
-
-
Wynn, T.A.1
|