Monocytes induce proximal tubular epithelial-mesenchymal transition through NF-kappa B dependent upregulation of ICAM-1

Journal of Cellular Biochemistry

Volumn 112, Issue 6, 2011, Pages 1585-1592

  Li, Qing ^a   Liu, Bi Cheng ^a   Lv, Lin Li ^a   Ma, Kun Ling ^a   Zhang, Xiao Liang ^a   Phillips, Aled O ^b  

^a SOUTHEAST UNIVERSITY   (China)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

EMT; ICAM 1; monocyte; NF B; proximal tubular cells

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; FIBRONECTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; UVOMORULIN;

ARTICLE; CELL STRUCTURE; COCULTURE; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; KIDNEY PROXIMAL TUBULE; MONOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

BLOTTING, WESTERN; CELL LINE; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; KIDNEY TUBULES, PROXIMAL; MONOCYTES; NF-KAPPA B; U937 CELLS;

EID: 79954550543     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23074     Document Type: Article

References (24)

1. Acloque H, Adams MS, Fishwick K, Bronner-Fraser M, Nieto MA,. 2009. Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease. J Clin Invest 119: 1438-1449.
2. Blaber R, Stylianou E, Clayton A, Steadman R,. 2003. Selective regulation of ICAM-1 and RANTES gene expression after ICAM-1 ligation on human renal fibroblasts. J Am Soc Nephrol 14: 116-127. (Pubitemid 36026303)
3. Blackwell T, Christman JW,. 1997. The role of nuclear factor-kB in cytokine gene regulation. Am J Respir Cell Mol Biol 17: 3-9. (Pubitemid 127500814)
4. Daniel L, Sichez H, Giorgi R, Dussol B, Figarella-Branger D, Pellissier JF, Berland Y,. 2001. Tubular lesions and tubular cell adhesion molecules for the prognosis of lupus nephritis. Kidney Int 60: 2215-2221. (Pubitemid 33070464)
5. IM A,. 1997. Transcription factors as activators of gene transcription: AP-1 and NF-kB. Monaldi Arch Chest Dis 52: 178-186.
6. Iwano M, Plieth D, Danoff TM, Xue C, Okada H, Neilson EG,. 2002. Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 110: 341-350. (Pubitemid 34847966)
7. Kalluri R, Weinberg RA,. 2009. The basics of epithelial-mesenchymal transition. J Clin Invest 119: 1420-1428.
8. Ko GJ, Boo CS, Jo SK, Cho WY, Kim HK,. 2008. Macrophages contribute to the development of renal fibrosis following ischaemia/reperfusion-induced acute kidney injury. Nephrol Dial Transplant 23: 842-852. (Pubitemid 351767562)
9. Lavaud S, Michel O, Sassy-Prigent C, Heudes D, Bazin R, Bariety J, Chevalier J,. 1996. Early influx of glomerular macrophages precedes glomerulosclerosis in the obese Zucker rat model. J Am Soc Nephrol 7: 2604-2615. (Pubitemid 27469567)
10. Le Hir M, Besse-Eschmann V,. 2003. A novel mechanism of nephron loss in a murine model of crescentic glomerulonephritis. Kidney Int 63: 591-599. (Pubitemid 36126804)
11. Li MXLB,. 2007. Epithelial to mesenchymal transition in the progression of tubulointerstitial fibrosis. Chin Med J (Engl) 120: 1925-1930. (Pubitemid 350111068)
12. Liu SFMA,. 2006. NF-kB activation as a pathological mechanism of septic shock and inflammation. Am J Physiol Lung Cell Mol Physiol 290: 622-645.
13. Liu Y,. 2004. Epithelial to mesenchymal transition in renal fibrogenesis: Pathologic significance, molecular mechanism, and therapeutic intervention. J Am Soc Nephrol 15: 1-12. (Pubitemid 38020692)
14. Ma FYLJ, Kitching AR, Manthey CL, Nikolic-Paterson DJ,. 2009. Targeting renal macrophage accumulation via c-fms kinase reduces tubular apoptosis but fails to modify progressive fibrosis in the obstructed rat kidney. Am J Physiol Renal Physiol 296: F177-F185.
15. Rastaldi MP, Ferrario F, Giardino L, Dell'Antonio G, Grillo C, Grillo P, Strutz F, Muller GA, Colasanti G, D'Amico G,. 2002. Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies. Kidney Int 62: 137-146. (Pubitemid 34754056)
16. Rothlein RDM, Marlin SD, Springer TA,. 1986. A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. J Immunol 137: 1270-1274. (Pubitemid 16041114)
17. Strutz F, Zeisberg M,. 2006. Renal fibroblasts and myofibroblasts in chronic kidney disease. J Am Soc Nephrol 17: 2992-2998. (Pubitemid 44707759)
18. Vielhauer VKO, Reichel CA, Anders HJ,. 2010. Targeting the recruitment of monocytes and macrophages in renal disease. Semin Nephrol 30: 831-833.
19. Vitalone MJ, O'Connell PJ, Jimenez-Vera E, Yuksel A, Wavamunno M, Fung CL, Chapman JR, Nankivell BJ,. 2008. Epithelial-to-mesenchymal transition in early transplant tubulointerstitial damage. J Am Soc Nephrol 19: 1571-1583.
20. Wang Y, Cao Q, Zheng G, Lee VW, Zheng D, Li X, Tan TK, Harris DC,. 2008. By homing to the kidney, activated macrophages potently exacerbate renal injury. Am J Pathol 172: 1491-1499. (Pubitemid 351793343)
21. Zeisberg EM, Tarnavski O, Zeisberg M, Dorfman AL, McMullen JR, Gustafsson E, Chandraker A, Yuan X, Pu WT, Roberts AB, Neilson EG, Sayegh MH, Izumo S, Kalluri R,. 2007. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat Med 13: 952-961. (Pubitemid 47222040)
22. Zeisberg M, Strutz F, Muller GA,. 2001. Renal fibrosis: An update. Curr Opin Nephrol Hypertens 10: 315-320. (Pubitemid 32424018)
23. Zhang XL, Selbi W, de la Motte C, Hascall V, Phillips AO,. 2005. Bone morphogenic protein-7 inhibits monocyte-stimulated TGF-beta1 generation in renal proximal tubular epithelial cells. J Am Soc Nephrol 16: 79-89. (Pubitemid 43073159)
24. Zhang XLSW, De La Motte C, Hascall V, Phillips A,. 2004. Renal proximal tubular epithelial cell transforming growth factor-beta1 generation and monocyte binding. Am J Pathol 165: 763-773. (Pubitemid 39129284)