메뉴 건너뛰기




Volumn 52, Issue 7, 2013, Pages 683-693

NUP98-NSD1 gene fusion and its related gene expression signature are strongly associated with a poor prognosis in pediatric acute myeloid leukemia

(17)  Shiba, Norio a,b   Ichikawa, Hitoshi c   Taki, Tomohiko d   Park, Myoung Ja a   Jo, Aoi c   Mitani, Sachiyo c   Kobayashi, Tohru b   Shimada, Akira e   Sotomatsu, Manabu a   Arakawa, Hirokazu b   Adachi, Souichi f   Tawa, Akio g   Horibe, Keizo h   Tsuchida, Masahiro i   Hanada, Ryoji j   Tsukimoto, Ichiro k   Hayashi, Yasuhide a  


Author keywords

[No Author keywords available]

Indexed keywords

CD135 ANTIGEN; HYBRID PROTEIN; K RAS PROTEIN; NUCLEAR RECEPTOR BINDING SET DOMAIN PROTEIN 1; NUCLEOPORIN 98; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HOXA1; TRANSCRIPTION FACTOR HOXA10; UNCLASSIFIED DRUG; WT1 PROTEIN;

EID: 84877923461     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.22064     Document Type: Article
Times cited : (86)

References (42)
  • 2
    • 0030916736 scopus 로고    scopus 로고
    • The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase case, DDX10
    • Arai Y, Hosoda F, Kobayashi H, Kawakami K, Takahara J. 1997. The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase case, DDX10. Blood 89:3936-3944.
    • (1997) Blood , vol.89 , pp. 3936-3944
    • Arai, Y.1    Hosoda, F.2    Kobayashi, H.3    Kawakami, K.4    Takahara, J.5
  • 3
    • 0036530203 scopus 로고    scopus 로고
    • A cryptic t(5;11)(q35;p15.5) in 2 children with acute myeloid leukemaia with apparently normal karyotypes, identified by a multiplex fluorescence in situ hybridization telomere assay
    • Brown J, Jawad M, Twigg SR, Saracoglu K, Sauerbrey A, Thomas AE, Eils R, Harbott J, Kearney L. 2002. A cryptic t(5;11)(q35;p15.5) in 2 children with acute myeloid leukemaia with apparently normal karyotypes, identified by a multiplex fluorescence in situ hybridization telomere assay. Blood 99:2526-2531.
    • (2002) Blood , vol.99 , pp. 2526-2531
    • Brown, J.1    Jawad, M.2    Twigg, S.R.3    Saracoglu, K.4    Sauerbrey, A.5    Thomas, A.E.6    Eils, R.7    Harbott, J.8    Kearney, L.9
  • 4
    • 0041662187 scopus 로고    scopus 로고
    • Cryptic t(5;11)(q35;p15.5) in adult de novo acute myelocytic leukemia with normal karyotype
    • Casas S, Aventín A, Nomdedéu J, Sierra J. 2003. Cryptic t(5;11)(q35;p15.5) in adult de novo acute myelocytic leukemia with normal karyotype. Cancer Genet Cytogenet 145:183.
    • (2003) Cancer Genet Cytogenet , vol.145 , pp. 183
    • Casas, S.1    Aventín, A.2    Nomdedéu, J.3    Sierra, J.4
  • 8
    • 28444473100 scopus 로고    scopus 로고
    • Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations
    • Döhner K, Schlenk RF, Habdank M, Scholl C, Rücker FG, Corbacioglu A, Bullinger L, Fröhling S, Döhner H. 2005. Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations. Blood 106:3740-3746.
    • (2005) Blood , vol.106 , pp. 3740-3746
    • Döhner, K.1    Schlenk, R.F.2    Habdank, M.3    Scholl, C.4    Rücker, F.G.5    Corbacioglu, A.6    Bullinger, L.7    Fröhling, S.8    Döhner, H.9
  • 10
    • 27244452986 scopus 로고    scopus 로고
    • Genetics of myeloid malignancies: Pathogenetic and clinical implications
    • Frohling S, Scholl C, Gilliland DG, Levine RL. 2005. Genetics of myeloid malignancies: Pathogenetic and clinical implications. J Clin Oncol 23:6285-6295.
    • (2005) J Clin Oncol , vol.23 , pp. 6285-6295
    • Frohling, S.1    Scholl, C.2    Gilliland, D.G.3    Levine, R.L.4
  • 11
    • 83455220210 scopus 로고    scopus 로고
    • NUP98 gene fusions and hematopoietic malignancies: Common themes and new biological insights
    • Gough SM, Slape CI, Aplan PD. 2011. NUP98 gene fusions and hematopoietic malignancies: Common themes and new biological insights. Blood 118:6247-6257.
    • (2011) Blood , vol.118 , pp. 6247-6257
    • Gough, S.M.1    Slape, C.I.2    Aplan, P.D.3
  • 17
    • 60649104272 scopus 로고    scopus 로고
    • Age-associated difference in gene expression of paediatric acute myelomonocytic lineage leukaemia (FAB M4 and M5 subtypes) and its correlation with prognosis
    • Jo A, Tsukimoto I, Ishii E, Asou N, Mitani S, Shimada A, Igarashi T, Hayashi Y, Ichikawa H. 2009. Age-associated difference in gene expression of paediatric acute myelomonocytic lineage leukaemia (FAB M4 and M5 subtypes) and its correlation with prognosis. Br J Haematol 144:917-929.
    • (2009) Br J Haematol , vol.144 , pp. 917-929
    • Jo, A.1    Tsukimoto, I.2    Ishii, E.3    Asou, N.4    Mitani, S.5    Shimada, A.6    Igarashi, T.7    Hayashi, Y.8    Ichikawa, H.9
  • 20
    • 79952092487 scopus 로고    scopus 로고
    • Molecular genetics of adult acute myeloid leukemia: Prognostic and therapeutic implications
    • Marcucci G, Haferlach T, Döhner H. 2011. Molecular genetics of adult acute myeloid leukemia: Prognostic and therapeutic implications. J Clin Oncol 29:475-486.
    • (2011) J Clin Oncol , vol.29 , pp. 475-486
    • Marcucci, G.1    Haferlach, T.2    Döhner, H.3
  • 21
    • 0034332196 scopus 로고    scopus 로고
    • A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells
    • Mochizuki N, Shimizu S, Nagasawa T, Tanaka H, Taniwaki M, Yokota J, Morishita K. 2000. A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells. Blood 96:3209-3214.
    • (2000) Blood , vol.96 , pp. 3209-3214
    • Mochizuki, N.1    Shimizu, S.2    Nagasawa, T.3    Tanaka, H.4    Taniwaki, M.5    Yokota, J.6    Morishita, K.7
  • 23
    • 0141482125 scopus 로고    scopus 로고
    • The cardiac homeobox gene NKX2-5 is deregulated by juxtaposition with BCL11B in pediatric T-ALL cell lines via a novel t(5;14)(q35.1;q32.2)
    • Nagel S, Kaufmann M, Drexler HG, MacLeod RA. 2003. The cardiac homeobox gene NKX2-5 is deregulated by juxtaposition with BCL11B in pediatric T-ALL cell lines via a novel t(5;14)(q35.1;q32.2). Cancer Res 63:5329-5334.
    • (2003) Cancer Res , vol.63 , pp. 5329-5334
    • Nagel, S.1    Kaufmann, M.2    Drexler, H.G.3    MacLeod, R.A.4
  • 24
    • 27244452418 scopus 로고    scopus 로고
    • NUP98 fusion in human leukemia: Dysregulation of the nuclear pore and homeodomain proteins
    • Nakamura T. 2005. NUP98 fusion in human leukemia: Dysregulation of the nuclear pore and homeodomain proteins. Int J Hematol 82:21-27.
    • (2005) Int J Hematol , vol.82 , pp. 21-27
    • Nakamura, T.1
  • 27
    • 0032974961 scopus 로고    scopus 로고
    • Targeted disruption of the homeobox transcription factor Nkx2-3 in mice results in postnatal lethality and abnormal development of small intestine and spleen
    • Pabst O, Zweigerdt R, Arnold HH. 1999. Targeted disruption of the homeobox transcription factor Nkx2-3 in mice results in postnatal lethality and abnormal development of small intestine and spleen. Development 126:2215-2225.
    • (1999) Development , vol.126 , pp. 2215-2225
    • Pabst, O.1    Zweigerdt, R.2    Arnold, H.H.3
  • 28
    • 0036836507 scopus 로고    scopus 로고
    • Cryptic translocation t(5;11)(q35;p15.5) with involvement of the NSD1 and NUP98 genes without 5q deletion in childhood acute myeloid leukemia
    • Panarello C, Rosanda C, Morerio C. 2002. Cryptic translocation t(5;11)(q35;p15.5) with involvement of the NSD1 and NUP98 genes without 5q deletion in childhood acute myeloid leukemia. Genes Chromosomes Cancer 35:277-281.
    • (2002) Genes Chromosomes Cancer , vol.35 , pp. 277-281
    • Panarello, C.1    Rosanda, C.2    Morerio, C.3
  • 30
    • 79952078495 scopus 로고    scopus 로고
    • Biology, risk stratification, and therapy of pediatric acute leukemias: An update
    • Pui CH, Carroll WL, Meshinchi S, Arceci RJ. 2011. Biology, risk stratification, and therapy of pediatric acute leukemias: An update. J Clin Oncol 29:551-565.
    • (2011) J Clin Oncol , vol.29 , pp. 551-565
    • Pui, C.H.1    Carroll, W.L.2    Meshinchi, S.3    Arceci, R.J.4
  • 35
    • 33344471932 scopus 로고    scopus 로고
    • KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): a study of the Japanese Childhood AML Cooperative Study Group
    • Shimada A, Taki T, Tabuchi K, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Hayashi Y. 2006. KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): a study of the Japanese Childhood AML Cooperative Study Group. Blood 107:1806-1809.
    • (2006) Blood , vol.107 , pp. 1806-1809
    • Shimada, A.1    Taki, T.2    Tabuchi, K.3    Tawa, A.4    Horibe, K.5    Tsuchida, M.6    Hanada, R.7    Tsukimoto, I.8    Hayashi, Y.9
  • 36
    • 37549071079 scopus 로고    scopus 로고
    • Tandem duplications of MLL and FLT3 are correlated with poor prognoses in pediatric acute myeloid leukemia: a study of the Japanese childhood AML Cooperative Study Group
    • Shimada A, Taki T, Tabuchi K, Taketani T, Hanada R, Tawa A, Tsuchida M, Horibe K, Tsukimoto I, Hayashi Y. 2008. Tandem duplications of MLL and FLT3 are correlated with poor prognoses in pediatric acute myeloid leukemia: a study of the Japanese childhood AML Cooperative Study Group. Pediatr Blood Cancer 50:264-269.
    • (2008) Pediatr Blood Cancer , vol.50 , pp. 264-269
    • Shimada, A.1    Taki, T.2    Tabuchi, K.3    Taketani, T.4    Hanada, R.5    Tawa, A.6    Tsuchida, M.7    Horibe, K.8    Tsukimoto, I.9    Hayashi, Y.10
  • 37
    • 0036143026 scopus 로고    scopus 로고
    • The HOXD11 gene is fused to the NUP98 gene in acute myeloid leukemia with t(2;11)(q31;p15)
    • Taketani T, Taki T, Shibuya N, Ito E, Kitazawa J, Terui K, Hayashi Y. 2002a The HOXD11 gene is fused to the NUP98 gene in acute myeloid leukemia with t(2;11)(q31;p15). Cancer Res 62:33-37.
    • (2002) Cancer Res , vol.62 , pp. 33-37
    • Taketani, T.1    Taki, T.2    Shibuya, N.3    Ito, E.4    Kitazawa, J.5    Terui, K.6    Hayashi, Y.7
  • 38
    • 0036077515 scopus 로고    scopus 로고
    • The chromosome translocation t(7;11)(p15;p15) in acute myeloid leukemia results in fusion of the NUP98 gene with a HOXA cluster gene, HOXA13, but not HOXA9
    • Taketani T, Taki T, Ono R, Kobayashi Y, Ida K, Hayashi Y. 2002b. The chromosome translocation t(7;11)(p15;p15) in acute myeloid leukemia results in fusion of the NUP98 gene with a HOXA cluster gene, HOXA13, but not HOXA9. Genes Chromosomes Cancer 34:437-443.
    • (2002) Genes Chromosomes Cancer , vol.34 , pp. 437-443
    • Taketani, T.1    Taki, T.2    Ono, R.3    Kobayashi, Y.4    Ida, K.5    Hayashi, Y.6
  • 39
    • 0037102313 scopus 로고    scopus 로고
    • Novel NUP98-HOXC11 fusion gene resulted from a chromosomal break within exon 1 of HOXC11 in acute myeloid leukemia with t(11;12)(p15;q13)
    • Taketani T, Taki T, Shibuya N, Kikuchi A, Hanada R, Hayashi Y. 2002c Novel NUP98-HOXC11 fusion gene resulted from a chromosomal break within exon 1 of HOXC11 in acute myeloid leukemia with t(11;12)(p15;q13). Cancer Res 62:4571-4574.
    • (2002) Cancer Res , vol.62 , pp. 4571-4574
    • Taketani, T.1    Taki, T.2    Shibuya, N.3    Kikuchi, A.4    Hanada, R.5    Hayashi, Y.6
  • 40
    • 78149467263 scopus 로고    scopus 로고
    • High frequencies of simultaneous FLT3-ITD, WT1 and KIT mutations in hematological malignancies with NUP98-fusion genes
    • Taketani T, Taki T, Nakamura T, Kobayashi Y, Ito E, Fukuda S, Yamaguchi S, Hayashi Y. 2010. High frequencies of simultaneous FLT3-ITD, WT1 and KIT mutations in hematological malignancies with NUP98-fusion genes. Leukemia 24:1975-1977.
    • (2010) Leukemia , vol.24 , pp. 1975-1977
    • Taketani, T.1    Taki, T.2    Nakamura, T.3    Kobayashi, Y.4    Ito, E.5    Fukuda, S.6    Yamaguchi, S.7    Hayashi, Y.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.