Innate immunity in the Grid2Lc/+ mouse model of cerebellar neurodegeneration: Glial CD95/CD95L plays a non-apoptotic role in persistent neuron loss-associated inflammatory reactions in the cerebellum

Journal of Neuroinflammation

Volumn 10, Issue , 2013, Pages

  Vernet der Garabedian, Béatrice ^a,b   Derer, Paul ^a,b   Bailly, Yannick ^d   Mariani, Jean ^a,b,c  

^a SORBONNE UNIVERSITÉ   (France)

^b CNRS   (France)

^c HÔPITAL CHARLES FOIX   (France)

^d Max Planck/CNRS Group   (France)

Author keywords

Astrocyte; Cytokines; GFAP; Glial reaction; Grid2 gene; IL 6; Lurcher; Microglia; Soluble CD95L

Indexed keywords

FAS ANTIGEN; FAS LIGAND; INTERLEUKIN 6; CYTOKINE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR DELTA 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; CELL ACTIVATION; CELL COUNT; CELL LOSS; CEREBELLAR NEURODEGENERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEGENERATIVE DISEASE; ELECTRON MICROSCOPY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLIA CELL; INNATE IMMUNITY; MALE; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPATHOLOGY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WILD TYPE; ANIMAL; ASTROCYTE; C57BL MOUSE; CELL CULTURE; CELL DEATH; CEREBELLUM; GENETICS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; NERVE CELL; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SPINOCEREBELLAR DEGENERATION; ULTRASTRUCTURE;

ANIMALS; ANTIGENS, CD95; ASTROCYTES; BLOTTING, WESTERN; CELL DEATH; CELLS, CULTURED; CEREBELLUM; CYTOKINES; FAS LIGAND PROTEIN; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNITY, INNATE; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICE, NEUROLOGIC MUTANTS; MICROSCOPY, ELECTRON; NEURONS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, GLUTAMATE; SPINOCEREBELLAR DEGENERATIONS;

EID: 84877910246     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-10-65     Document Type: Article

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