TNF-α and IFN-γ regulate expression and function of the Fas system in the seminiferous epithelium

Journal of Immunology

Volumn 165, Issue 2, 2000, Pages 743-749

  Riccioli, Anna ^a   Starace, Donatella ^a   D'Alessio, Alessio ^a   Starace, Giuseppe ^b   Padula, Fabrizio ^a   De Cesaris, Paola ^c   Filippini, Antonio ^a   Ziparo, Elio ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; RECOMBINANT GAMMA INTERFERON; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL ONCOGENE; CONTROLLED STUDY; DOSE RESPONSE; IMMUNOREGULATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SEMINIFEROUS TUBULE; SERTOLI CELL;

EID: 0034662023     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.2.743     Document Type: Article

References (50)

1. Head, J. R., W. B. Neaves, and R. E. Billingham. 1983. Immune privilege in the testis. I. Basic parameters of allograft survival. Transplantation 36:423.
2. Dym, M., and D. W. Fawcett. 1970. The blood-testis barrier of the rat and the physiological compartimentation of the seminiferous epithelium. Biol. Reprod. 3:308.
3. De Cesaris, P., A. Filippini, C. Cervelli, A Riccioli, S. Muci, G. Starace, M. Stefanini, and E. Ziparo. 1992. Immunosuppressive molecules produced by Sertoli cells cultured in vitro: biological effects on lymphocytes. Biochem. Biophys. Res. Commun. 186:1639.
4. Riccioli, A., A. Filippini, P. De Cesaris, E. Barbacci, M. Stefanini, G. Starace, and E. Ziparo, 1995. Inflammatory mediators increase surface expression of inlegrin ligands, adhesion to lymphocytes, and secretion of interleukin 6 in mouse Sertoli cells. Proc. Natl. Acad. Sci. USA 92:5808.
5. Beligrau, D., D. Gold, H. Selawry, J. Moore, A. Franzusoff, and R. C. Duke. 1995. A role for CD95 ligand in preventing graft rejection. Nature 377:630.
6. Itoh, N., S. Yonehara, A. Ishii, M. Yonehara, S. Mizushima, M. Sameshima, A. Hase, Y. Seto, and S. Nagata. 1991. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66:233.
7. Lynch, D. H., F. Ramsdell, and M. R. Alderson. 1995. Fas and FasL in the homeostatic regulation of immune responses. Immunol. Today 16:569.
8. Watanabe-Fukunaga, R., C. I. Brannan, N. Itoh, S. Yonehara, N. G. Copeland, N. A. Jenkins, and S. Nagata. 1992. The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. J. Immunol. 148:1274.
9. Hanabuti, S., M. Koyanagi, A. Kawasaki, N. Shinohara, A. Matsuzawa, Y. Kobayashi, S. Yonehara, and H. Yagita. 1994. Fas and its ligand in a general mechanism of T cell-mediated cytotoxicity. Proc. Natl. Acad. Sci. USA 91:4930.
10. Hahne, M., T. Renno, M. Schroeter, M. Irmler, L. French, T. Bornard, H. R. MacDonald, and J. Tschopp. 1996. Activated B cells express functional Fas ligand. Eur. J. Immunol. 26:721.
11. Dhein, J., H. Walczak, C. Baumier, K. M. Debatin, and P. H. Krammer. 1995. Autocrine T-cell suicide mediated by Apo-1/Fas/CD95. Nature 373:438.
12. Graves, J. D., K. E. Graves, A. Craxton, E. G. Krebs, and E. A. Clark. 1998. A comparison of signaling requirements for apoptosis of human B lymphocytes induced by the B cell receptor and CD95/Fas. J. Immunol. 161:168.
13. Lynch, D. H., M. L. Watson, M. R. Alderson, P. R. Baum, R. E. Miller, T. Tough, M. Gibson, T. Davis-Smith, C. A. Smith, K. Hunter, et al. 1994. The mouse Fas ligand gene is mutated in gld mice and is part of a TNF family gene cluster. Immunity 1:131.
14. Watanabe-Fukunaga, R., C. I. Brannan, N. G. Copeland, N. A. Jenkins, and S. Nagata. 1992. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:314.
15. Katsikis, P. D., E. S. Wunderlich. C. A. Smith, and L. A. Herzenberg. 1995. Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. J. Exp. Med. 181:2029.
16. Griffith, T. S., T. Brunner, S. M. Fletcher, D. R. Green, and T. A. Ferguson. 1995. Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 270: 1189.
17. Suda, T., T. Takahashi, P. Goldstein, and S. Nagata. 1993. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75:1169.
18. French, L. E., M. Hahne, I. Viard, G. Radlgruber, R. Zanone, K. Becker, C. Muller, and J. Tschopp. 1996. Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover. J. Cell Biol. 133:335.
19. Lee. J., J. H. Richburg, S. C. Younkin, and K. Boekelheide. 1997. The Fas system is a key regulator of germ cell apoptosis in the testis. Endocrinology 138:2081.
20. Pentikainen, V., K. Erkkila, and L. Dunkel. 1999. Fas regulates germ cell apoptosis in the human testis in vitro. Am. J. Physiol. 276:E310.
21. De, S. K., H. L. Chen, J. L. Pace, J. S. Hunt, P. F. Terranova, and G. C. Enders. 1993. Expression of tumor necrosis factor-α in mouse spermatogenic cells. Endocrinology 133:389.
22. Boockfor, F. R., and L. K. Schwarz. 1991. Effects of interleukin-6, interleukin-2, and tumor necrosis factor α on transferrin release from Sertoli cells in culture. Endocrinology 129:256.
23. De Cesaris, P., D. Starace, A, Riccioli, F. Padula, A. Filippini, and E. Ziparo. 1998. Tumor necrosis factor-α induces interleukin-6 production and integrin ligand expression by distinct transduction pathways. J. Biol. Chem. 273:7566.
24. De Cesaris, P., D. Starace, G. Starace, A. Filippini, M. Stefanini, and E. Ziparo. 1999. Activation of Jun N-terminal Kinase/Stress-activated protein kinase pathway by tumor necrosis factor α leads to intercellular adhesion molecule-1 expression. J. Biol. Chem. 274:28978.
25. Spanaus, K. S., R. Schlapbach, and A. Fontana. 1998. TNF-α and IFN-γ render microglia sensitive to Fas ligand-induced apoptosis by induction of Fas expression and down-regulation of Bcl-2 and Bcl-xL. Eur. J. Immunol. 28:4398.
26. Arnold, R.. M. Seifert, K. Asadullah, and H. D. Volk. 1999. Crosstalk between keratinocytes and T lymphocytes via Fas/Fas ligand interaction: modulation by cytokines. J. Immunol. 162:7140.
27. Van Zee, K. J., T. Kohno, E. Fischer, C. S. Rock, L. L. Moldawer, and S. F. Lowry. 1992. Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo. Proc. Natl. Acad. Sci. USA 89:4845.
28. Alcami, A., and G. L. Smith. 1992. A soluble receptor for interleukin-1β encoded by vaccinia virus: a novel mechanism of virus modulation of the host response to infection. Cell 71:153.
29. Papoff, G., I. Cascino, A. Eramo, G. Starace, DH. Lynch, and G. Ruberti. 1996. An N-terminal domain shared by Fas/Apo-1 (CD95) soluble variants prevents cell death in vitro. J. Immunol. 156:4622.
30. Hughes, D. P., and I. N. Crispe, 1995. A naturally occurring soluble isoform of murine Fas generated by alternative splicing. J. Exp. Med. 182:1395.
31. Tanaka, M., T. Suda, T. Takahashi, and S. Nagata. 1995. Expression of the functional soluble form of human Fas ligand in activated lynphocytes. EMBO J. 14:1129.
32. Cheng, J., T. Zhou, C. Liu, J. P. Shapiro, M. J. Brauer, M. C. Kiefer, P. J. Barr, and J. D. Mountz. 1994. Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. Science 263:1759.
33. Suda, T., H. Hashimoto, M. Tanaka, T. Ochi, and S. Nagata. 1997. Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing. J. Exp. Med 186:2045.
34. Takahashi, T., M. Tanaka, C. I. Brannan, N. A. Jenkins, N. G. Copeland, T. Suda, and S. Nagata. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76:969.
35. Kohno, S., E. Ziparo, L. F. Marek, and K. S. Tung. 1983. Murine Sertoli cells: major histocompatibility antigens and glycoconjugates. J. Keprod. Immunol. 5:339.
36. Galdieri, M., E. Ziparo, F. Palombi, M. A. Russe, and M. Stefanini. 1981. Pure Sertoli cell cultures: new model for the study of somatic-germ cell interaction. J. Androl. 5:249.
37. Palombi, F., and C. Di Carlo. 1988. Alkaline phosphatase is a marker for myoid cells in cultures of rat peritubular and tubular tissue. Biol. Reprod. 39:1101.
38. Albanese, J., S. Meterissian, M. Kontogiannea, C. Dubreuil, A. Hand, S. Sorba, and N. Dainiak. 1998. Biologically active Fas antigen and its cognate ligand are expressed on plasma membrane-derived extracellular vesicles. Blood 91:3862.
39. Luttmann, W., A. Opfer, E. Dauer, M. Foerster, H. Matthys, H. Eibel, K. Schulze-Osthoff, C. Kroegel, and J. C. Virchow. 1998. Differential regulation of CD95 (Fas/APO-1) expression in human blood eosinophils. Eur. J. Immunol. 28:2057.
40. Richardson, B. C., N. D. Lalwani, K. J. Johnson, and R. M. Marks. 1994. Fas ligation triggers apoptosis in macrophages but not endothelial cells. Eur. J. Immunol. 24:2640.
41. Hakuno, N., T. Koji, T. Yano, N. Kobayashi, O. Tsutsumi, Y. Taketani, and P. K. Nakane. 1996. Fas/APO-1/CD95 system as a mediator of granulosa cell apoptosis in ovarian follicle atresia. Endocrinology 137:1938.
42. Hughes, S. J., Y. Nambu, O. S. Soldes, D. Hamstra, A. Rehemtulla, M. D. Iannettoni, M. B. Orringer, and D. G. Beer. 1997. Fas/APO-1 (CD95) is not translocated to the cell membrane in esophageal adenocarcinoma. Cancer Res. 57:5571.
43. Sorrentino, V., M. Giorgi, R. Geremia, P. Besmer, and P. Rossi. 1991. Expression of the c-kit proto-oncogene in the murine male germ cells. Oncogene 6:149.
44. Giordano, C., G. Stassi, R. De Maria, M. Todaro, P. Richiusa, G. Papoff, G. Ruberti, M. Bagnasco, R. Testi, and A. Galluzzo. 1997. Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis. Science 275:960.
45. Nozawa, K., N. Kayagaki, Y. Tokano, H. Yagita, K. Okumura, and H. Hasimoto. 1997. Soluble Fas (APO-1, CD95) and soluble Fas ligand in rheumatic diseases. Arthritis Rheum. 40:1126.
46. Dowling, P., G. Shang, S. Raval, J. Menonna, S. Cook, and W. Husar. 1996. Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain. J. Exp. Med, 184:1513.
47. Miwa, K., M. Asano, R. Horai, Y. Iwakura, S. Nagata, and T. Suda. 1998. Caspase I-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand. Nat. Med. 4:1287.
48. Gerard, N., V. Syed, W. Bardin, N. Genetet, and B. Jegou. 1991. Sertoli cells are the site of interleukin-1α synthesis in rat testis. Mol. Cell Endocrinol. 82:R13.
49. Woolveridge, I., M. de Boer-Brouwer, M. F. Taylor, K. J. Teerds, F. C. Wu, and I. D. Morris. 1999. Apoptosis in the rat spermatogenic epithelium following androgen withdrawal: changes in apoptosis-related genes. Biol. Reprod. 60:461.
50. Dejucq, N., I. Dugast, A. Ruffault, P. H. van der Meide, and B. Jegou. 1995. Interferon-α and -γ expression in the rat testis. Endocrinology 136:4925.