Stimulating Myocardial Regeneration with Periostin Peptide in Large Mammals Improves Function Post-Myocardial Infarction but Increases Myocardial Fibrosis

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Ladage, Dennis ^a,b   Yaniz Galende, Elisa ^a   Rapti, Kleopatra ^a   Ishikawa, Kiyotake ^a   Tilemann, Lisa ^a   Shapiro, Scott ^a   Takewa, Yoshiaki ^a   Muller Ehmsen, Jochen ^b   Schwarz, Martin ^a   Garcia, Mario J ^a   Sanz, Javier ^a   Hajjar, Roger J ^a   Kawase, Yoshiaki ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR AGENT; GELFOAM; RECOMBINANT PERIOSTIN PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE REGULATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EXPERIMENTAL PIG; FEMALE; HEART INDEX; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBROSIS; HEART VENTRICLE EJECTION TIME; MALE; MUSCLE REGENERATION; MYOFIBROBLAST; NONHUMAN; RAT; TISSUE REPAIR; TREATMENT DURATION;

ANGIOGENESIS INDUCING AGENTS; ANIMALS; CELL ADHESION MOLECULES; CELL PROLIFERATION; CELLS, CULTURED; CORONARY VESSELS; DRUG DELIVERY SYSTEMS; FEMALE; FIBROSIS; GELATIN SPONGE, ABSORBABLE; HEART; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; MYOFIBROBLASTS; REGENERATION; SUS SCROFA; VENTRICULAR FUNCTION, LEFT;

EID: 84877890765     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059656     Document Type: Article

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