Synthesis, characterization and antitumor evaluation of CMCS-DTX conjugates as novel delivery platform for docetaxel

International Journal of Pharmaceutics

Volumn 451, Issue 1-2, 2013, Pages 41-49

  Liu, Fengxi ^a   Feng, Lixia ^a   Zhang, Li ^a   Zhang, Xu ^a   Zhang, Na ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Antitumor effect; Carboxymethyl chitosan; Docetaxel; Polymer drug conjugates

Indexed keywords

CARBOXYMETHYL CHITOSAN DOCETAXEL CONJUGATE; CHITOSAN; DOCETAXEL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MELANOMA; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SURVIVAL TIME; ZETA POTENTIAL;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; CHITOSAN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; FEMALE; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MAXIMUM TOLERATED DOSE; MELANOMA, EXPERIMENTAL; MICE; NANOPARTICLES; PARTICLE SIZE; SURVIVAL RATE; TAXOIDS; TIME FACTORS;

EID: 84877872775     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.04.020     Document Type: Article

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