-
1
-
-
17044386953
-
Type 2 diabetes: Principles of pathogenesis and therapy
-
Stunvoll M, Goldstein BJ, van Haeften TW. Type 2 diabetes: principles of pathogenesis and therapy. Lancet 2005;365:333-46
-
(2005)
Lancet
, vol.365
, pp. 333-346
-
-
Stunvoll, M.1
Goldstein, B.J.2
Van Haeften, T.W.3
-
2
-
-
84866479258
-
-
Geneva: world Health Organization [Last accessed 10 October 2012]
-
The World health statistics 2012 reports. Geneva: world Health Organization. 2012. Available from: http://www.who. int/mediacentre/news/ releases/2012/ world-health-statistics-20120516/en/ [Last accessed 10 October 2012]
-
(2012)
The World Health Statistics 2012 Reports
-
-
-
3
-
-
57749177096
-
Endothelial dysfunction and diabetes: Roles of hyperglycaemia, impaired insulin signalling and obesity
-
Bakker W, Eringa EC, Sipkema P, van Hinsbergh VWM. Endothelial dysfunction and diabetes: roles of hyperglycaemia, impaired insulin signalling and obesity. Cell Tissue Res 2009;335:165-89
-
(2009)
Cell Tissue Res
, vol.335
, pp. 165-189
-
-
Bakker, W.1
Eringa, E.C.2
Sipkema, P.3
Van Hinsbergh, V.W.M.4
-
4
-
-
38149117097
-
Chronic hyperglycemia and nitric oxide bioavailability play a pivotal role in pro-atherogenic vascular modifications
-
Pandolfi A, De Filips EA. Chronic hyperglycemia and nitric oxide bioavailability play a pivotal role in pro-atherogenic vascular modifications. Genes Nutr 2007;2:195-208
-
(2007)
Genes Nutr
, vol.2
, pp. 195-208
-
-
Pandolfi, A.1
De Filips, E.A.2
-
5
-
-
0344791695
-
Determinants of atherosclerosis in the young: Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group
-
McGill HD, McMahan CA. Determinants of atherosclerosis in the young: pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group. Am J Cardiol 1998;82:30-6
-
(1998)
Am J Cardiol
, vol.82
, pp. 30-36
-
-
McGill, H.D.1
McMahan, C.A.2
-
6
-
-
0009547624
-
Consensus statement role of cardiovascular risk factors in prevention and treatment of macrovascular disease in diabetes
-
American Diabetes Association
-
American Diabetes Association. Consensus statement role of cardiovascular risk factors in prevention and treatment of macrovascular disease in diabetes. Diabetes Care 1989;12:573-9
-
(1989)
Diabetes Care
, vol.12
, pp. 573-579
-
-
-
7
-
-
0025824726
-
The fibrinolytic system in diabetes mellitus
-
Gough SCL, Grant PJ. The fibrinolytic system in diabetes mellitus. Diabetic Med 1991;8:898-905
-
(1991)
Diabetic Med
, vol.8
, pp. 898-905
-
-
Scl, G.1
Grant, P.J.2
-
8
-
-
16844378797
-
PPARgamma and atherosclerosis
-
Staels B. PPARgamma and atherosclerosis. Curr Med Res Opin 2005;21(Suppl 1):13-20
-
(2005)
Curr Med Res Opin
, vol.21
, Issue.SUPPL. 1
, pp. 13-20
-
-
Staels, B.1
-
10
-
-
81855222104
-
Long-Term Dipeptidyl-Peptidase 4 Inhibition Reduces Atherosclerosis and Inflammation via Effects on Monocyte Recruitment and Chemotaxis
-
Shah Z, Kampfrath T, Deiuliis JA, et al. Long-Term Dipeptidyl-Peptidase 4 Inhibition Reduces Atherosclerosis and Inflammation via Effects on Monocyte Recruitment and Chemotaxis. Circulation 2011;124(21):2338-49
-
(2011)
Circulation
, vol.124
, Issue.21
, pp. 2338-2349
-
-
Shah, Z.1
Kampfrath, T.2
Deiuliis, J.A.3
-
11
-
-
79951884751
-
Glucagon-like peptide-1-based therapies and cardiovascular disease: Looking beyond glycaemic control
-
Anagnostis P, Athyros VG, Adamidou F, et al. Glucagon-like peptide-1-based therapies and cardiovascular disease: looking beyond glycaemic control. Diabetes Obes Metab 2011;13:302-12 .
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 302-312
-
-
Anagnostis, P.1
Athyros, V.G.2
Adamidou, F.3
-
12
-
-
77958540127
-
Vildagliptin: A review of its use in type 2 diabetes mellitus
-
Keating GM. Vildagliptin: a review of its use in type 2 diabetes mellitus. Drugs 2010;70:2089-112
-
(2010)
Drugs
, vol.70
, pp. 2089-2112
-
-
Keating, G.M.1
-
15
-
-
33646513010
-
Coagulation and atherothrombotic disease
-
Ajjan R, Grant PJ. Coagulation and atherothrombotic disease. Atherosclerosis 2006;186:240-59
-
(2006)
Atherosclerosis
, vol.186
, pp. 240-259
-
-
Ajjan, R.1
Grant, P.J.2
-
16
-
-
61349157950
-
Cardiovascular disease and heritability of the prothrombotic state
-
Ajjan RA, Ariens RA. Cardiovascular disease and heritability of the prothrombotic state. Blood Rev 2009;23:67-78
-
(2009)
Blood Rev
, vol.23
, pp. 67-78
-
-
Ajjan, R.A.1
Ariens, R.A.2
-
18
-
-
0034915177
-
Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect?
-
Dandona P, Aljada A, Mohanty P, et al. Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect? J Clin Endocinol Metab 2001;86:3257-65
-
(2001)
J Clin Endocinol Metab
, vol.86
, pp. 3257-3265
-
-
Dandona, P.1
Aljada, A.2
Mohanty, P.3
-
19
-
-
0033968126
-
Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle
-
Cusi K, Maezono K, Osman A, et al. Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle. J Clin Invest 2000;105:311-20
-
(2000)
J Clin Invest
, vol.105
, pp. 311-320
-
-
Cusi, K.1
Maezono, K.2
Osman, A.3
-
20
-
-
0034639491
-
Hyperinsulinemia, hyperglycemia, and impaired hemostasis: The Framingham Offspring Study
-
Meigs JB, Mittleman MA, Nathan DM, et al. Hyperinsulinemia, hyperglycemia, and impaired hemostasis: the Framingham Offspring Study. JAMA 2000;283:221-8
-
(2000)
JAMA
, vol.283
, pp. 221-228
-
-
Meigs, J.B.1
Mikati, M.A..2
Nathan, D.M.3
-
21
-
-
2642535951
-
Inflammation as a cardiovascular risk factor
-
Willerson JT, Ridker PM. Inflammation as a cardiovascular risk factor. Circulation 2004;109(Suppl 2):2-10
-
(2004)
Circulation
, vol.109
, Issue.SUPPL. 2
, pp. 2-10
-
-
Willerson, J.T.1
Ridker, P.M.2
-
22
-
-
0023940640
-
Cachectin/TNF and IL-1 induced by glucose-modified proteins; Role in normal tissue remodeling
-
Vlassara H, Brownlee M, Manogue KR, et al. Cachectin/TNF and IL-1 induced by glucose-modified proteins; role in normal tissue remodeling. Science 1988;240:1546-8
-
(1988)
Science
, vol.240
, pp. 1546-1548
-
-
Vlassara, H.1
Brownlee, M.2
Manogue, K.R.3
-
23
-
-
0033366583
-
Body mass index, diabetes, and C-reactive protein among U.S. adults
-
Ford ES. Body mass index, diabetes, and C-reactive protein among U.S. adults. Diabetes Care 1999;22:1971-7
-
(1999)
Diabetes Care
, vol.22
, pp. 1971-1977
-
-
Ford, E.S.1
-
24
-
-
0036900418
-
Insulin-regulated increase of soluble vascular adhesion protein-1 in diabetes
-
Salmi M, Stolen C, Jousilahti P, et al. Insulin-regulated increase of soluble vascular adhesion protein-1 in diabetes. Am J Pathol 2002;161:2255-62
-
(2002)
Am J Pathol
, vol.161
, pp. 2255-2262
-
-
Salmi, M.1
Stolen, C.2
Jousilahti, P.3
-
25
-
-
4043110643
-
Evolving concepts in the triad of atherosclerosis, inflammation and thrombosis
-
Corti R, Hutter R, Badimon JJ, Fuster V. Evolving concepts in the triad of atherosclerosis, inflammation and thrombosis. J Thromb Thrombolysis 2004;17:35-44
-
(2004)
J Thromb Thrombolysis
, vol.17
, pp. 35-44
-
-
Corti, R.1
Hutter, R.2
Badimon, J.J.3
Fuster, V.4
-
26
-
-
57649188618
-
Hypoglycaemic treatment of type 2 diabetes: Targeting the endothelium
-
Nathanson D, Nystrom T. Hypoglycaemic treatment of type 2 diabetes: targeting the endothelium. Mol Cell Endocrinol 2009;297:112-26
-
(2009)
Mol Cell Endocrinol
, vol.297
, pp. 112-126
-
-
Nathanson, D.1
Nystrom, T.2
-
27
-
-
0028804679
-
Hepsin a putative membrane-associated serine protease, activates human factor VII and initiates a pathway of blood coagulation on the cell surface leading to thrombin formation
-
Kazama Y, Hamamoto T, Foster DC, Kisiel W. Hepsin a putative membrane-associated serine protease, activates human factor VII and initiates a pathway of blood coagulation on the cell surface leading to thrombin formation. J Biol Chem 1995;270:66-72
-
(1995)
J Biol Chem
, vol.270
, pp. 66-72
-
-
Kazama, Y.1
Hamamoto, T.2
Foster, D.C.3
Kisiel, W.4
-
28
-
-
0034161567
-
Surface expression and functional characterization of alpha-granule factor v in human platelets: Effects of ionophore A23187, thrombin, collagen, and convulxin
-
Alberio L, Safa O, Clemetson KJ, et al. Surface expression and functional characterization of alpha-granule factor V in human platelets: effects of ionophore A23187, thrombin, collagen, and convulxin. Blood 2000;95:1694-702
-
(2000)
Blood
, vol.95
, pp. 1694-1702
-
-
Alberio, L.1
Safa, O.2
Clemetson, K.J.3
-
29
-
-
0030818804
-
Fibrinogen and diabetes mellitus: Is it time for intervention trials?
-
Ceriello A. Fibrinogen and diabetes mellitus: is it time for intervention trials? Diabetologia 1997;40:731-4
-
(1997)
Diabetologia
, vol.40
, pp. 731-734
-
-
Ceriello, A.1
-
30
-
-
0035093810
-
Diabetes mellitus: A hypercoagulable state
-
Carr ME. Diabetes mellitus: a hypercoagulable state. J Diabetes Complications 2001;15:44-54 .
-
(2001)
J Diabetes Complications
, vol.15
, pp. 44-54
-
-
Carr, M.E.1
-
31
-
-
77955978934
-
Coagulation profile in diabetes and its association with diabetic microvascular complications
-
Madan R, Gupta B, Saluja S, et al. Coagulation profile in diabetes and its association with diabetic microvascular complications. JAPI 2010;58:481-4
-
(2010)
JAPI
, vol.58
, pp. 481-484
-
-
Madan, R.1
Gupta, B.2
Saluja, S.3
-
32
-
-
18644371782
-
Type 2 diabetes: An atherothrombotic syndrome
-
Dunn EJ, Grant PJ. Type 2 diabetes: an atherothrombotic syndrome. Curr Mol Med 2005;5:323-32
-
(2005)
Curr Mol Med
, vol.5
, pp. 323-332
-
-
Dunn, E.J.1
Grant, P.J.2
-
33
-
-
0015383025
-
Increased platelet aggregation in diabetes mellitus
-
Kwaan HC, Colwell JA, Cruz S, et al. Increased platelet aggregation in diabetes mellitus. J Lab Clin Med 1972;80:236-46
-
(1972)
J Lab Clin Med
, vol.80
, pp. 236-246
-
-
Kwaan, H.C.1
Colwell, J.A.2
Cruz, S.3
-
34
-
-
0035178346
-
Increased synthesis of thromboxane A (2) and expression of procoagulant activity by monocytes in response to arachidonic acid in diabetes mellitus
-
Konieczkowski M, Skrinska VA. Increased synthesis of thromboxane A (2) and expression of procoagulant activity by monocytes in response to arachidonic acid in diabetes mellitus. Prostaglandins Leukot Essent Fatty Acids 2001;65:133-8
-
(2001)
Prostaglandins Leukot Essent Fatty Acids
, vol.65
, pp. 133-138
-
-
Konieczkowski, M.1
Skrinska, V.A.2
-
35
-
-
0026752666
-
Atherosclerosis Risk in Communities (ARIC) Study Investigators. Relations between hemostasis variables and cardiovascular risk factors in middle-aged adults
-
Folsom AR, Conlan MG, Davis CE, et al. Atherosclerosis Risk in Communities (ARIC) Study Investigators. Relations between hemostasis variables and cardiovascular risk factors in middle-aged adults. Ann Epidemiol 1992;2:481-94
-
(1992)
Ann Epidemiol
, vol.2
, pp. 481-494
-
-
Folsom, A.R.1
Conlan, M.G.2
Davis, C.E.3
-
36
-
-
0032954652
-
The Atherosclerosis Risk in Communities (ARIC) Study, Factor VIII and other hemostasis variables are related to incident diabetes in adults
-
Duncan BB, Schmidt MI, Offenbacher S, et al. The Atherosclerosis Risk in Communities (ARIC) Study, Factor VIII and other hemostasis variables are related to incident diabetes in adults. Diabetes Care 1999;22:767-72
-
(1999)
Diabetes Care
, vol.22
, pp. 767-772
-
-
Duncan, B.B.1
Schmidt, M.I.2
Offenbacher, S.3
-
37
-
-
0033832185
-
Elevation of fibrinogen and thrombin-antithrombin III complex levels of type 2 diabetes mellitus patients with retinopathy and nephropathy
-
Asakawa H, Tokunaga K, Kawakami F. Elevation of fibrinogen and thrombin-antithrombin III complex levels of type 2 diabetes mellitus patients with retinopathy and nephropathy. J Diabetes Complications 2000;14:121-6
-
(2000)
J Diabetes Complications
, vol.14
, pp. 121-126
-
-
Asakawa, H.1
Tokunaga, K.2
Kawakami, F.3
-
38
-
-
0032910598
-
Activation of the tissue factor pathway of blood coagulation during prolonged hyperglycemia in young healthy men
-
Rao AK, Chouhan V, Chen X, et al. Activation of the tissue factor pathway of blood coagulation during prolonged hyperglycemia in young healthy men. Diabetes 1999;48:1156-61
-
(1999)
Diabetes
, vol.48
, pp. 1156-1161
-
-
Rao, A.K.1
Chouhan, V.2
Chen, X.3
-
39
-
-
0037044431
-
Plasma von Willebrand factor and soluble p-selectin as indices of endothelial damage and platelet activation in 1321 patients with nonvalvular atrial fibrillation: Relationship to stroke risk factors
-
Conway DS, Pearce LA, Chin BS, et al. Plasma von Willebrand factor and soluble p-selectin as indices of endothelial damage and platelet activation in 1321 patients with nonvalvular atrial fibrillation: relationship to stroke risk factors. Circulation 2002;106:1962-7
-
(2002)
Circulation
, vol.106
, pp. 1962-1967
-
-
Conway, D.S.1
Pearce, L.A.2
Chin, B.S.3
-
41
-
-
0034900836
-
Atherosclerosis Risk in Communities. Cross-sectional association of soluble thrombomodulin with mild peripheral artery disease; The ARIC study
-
Salomaa V, Matei C, Aleksic N, et al. Atherosclerosis Risk in Communities. Cross-sectional association of soluble thrombomodulin with mild peripheral artery disease; the ARIC study. Atherosclerosis 2001;157:309-14
-
(2001)
Atherosclerosis
, vol.157
, pp. 309-314
-
-
Salomaa, V.1
Matei, C.2
Aleksic, N.3
-
42
-
-
0033050497
-
The Insulin Resistance Atherosclerosis Study (IRAS) Relative contribution of insulin and its precursors to fibrinogen and PAI-1 in a large population with different states of glucose tolerance
-
Festa A, Agostino R, Mykkanen L, et al. The Insulin Resistance Atherosclerosis Study (IRAS). Relative contribution of insulin and its precursors to fibrinogen and PAI-1 in a large population with different states of glucose tolerance. Arterioscler Thromb Vasc Biol 1999;19:562-8
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 562-568
-
-
Festa, A.1
Agostino, R.2
Mykkanen, L.3
-
43
-
-
0035574670
-
Plasminogen activator inhibitor type 1 is increased in the arterial wall of type II diabetic subjects
-
Pandolfi A, Cetrullo D, Polishuck R, et al. Plasminogen activator inhibitor type 1 is increased in the arterial wall of type II diabetic subjects. Arterioscler Thromb Vasc Biol 2001;21:1378-82
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1378-1382
-
-
Pandolfi, A.1
Cetrullo, D.2
Polishuck, R.3
-
44
-
-
0030761061
-
Thrombomodulin and induced tissue factor expression on monocytes as markers of diabetic microangiopathy: A prospective study on hemostasis and lipoproteins in insulin-dependent diabetes mellitus
-
Reverter JL, Reverter JC, Tassies D, et al. Thrombomodulin and induced tissue factor expression on monocytes as markers of diabetic microangiopathy: a prospective study on hemostasis and lipoproteins in insulin-dependent diabetes mellitus. Am J Hematol 1997;56:93-9
-
(1997)
Am J Hematol
, vol.56
, pp. 93-99
-
-
Reverter, J.L.1
Reverter, J.C.2
Tassies, D.3
-
46
-
-
1842454746
-
Clinical interest of PPARs ligands. Particular benefit in type 2 diabetes and metabolic syndrome
-
Verges B. Clinical interest of PPARs ligands. Particular benefit in type 2 diabetes and metabolic syndrome. Diabetes Metab 2004;30:7-12
-
(2004)
Diabetes Metab
, vol.30
, pp. 7-12
-
-
Verges, B.1
-
47
-
-
14744284119
-
Effect of rosiglitazone on circulating vascular and inflammatory markers in insulin-resistant subjects
-
Chu JW, Abbasi F, Lamendola C, et al. Effect of rosiglitazone on circulating vascular and inflammatory markers in insulin-resistant subjects. Diabetes Vasc Dis Res 2005;2:37-41
-
(2005)
Diabetes Vasc Dis Res
, vol.2
, pp. 37-41
-
-
Chu, J.W.1
Abbasi, F.2
Lamendola, C.3
-
48
-
-
0034126428
-
Effects of troglitazone on blood concentrations of plasminogen activator inhibitor 1 in patients with type 2 diabetes and in lean and obese normal subjects
-
Kruszynska YT, Yu JG, Olefsky JM, et al. Effects of troglitazone on blood concentrations of plasminogen activator inhibitor 1 in patients with type 2 diabetes and in lean and obese normal subjects. Diabetes 2000;49:633-9
-
(2000)
Diabetes
, vol.49
, pp. 633-639
-
-
Kruszynska, Y.T.1
Yu, J.G.2
Olefsky, J.M.3
-
49
-
-
20444439480
-
A comparison of the effects of pioglitazone and rosiglitazone combined with glimepiride on prothrombotic state in type 2 diabetic patients with the metabolic syndrome
-
Derosa G, Cicero AF, Gaddi A, et al. A comparison of the effects of pioglitazone and rosiglitazone combined with glimepiride on prothrombotic state in type 2 diabetic patients with the metabolic syndrome. Diabetes Res Clin Pract 2005;69:5-13
-
(2005)
Diabetes Res Clin Pract
, vol.69
, pp. 5-13
-
-
Derosa, G.1
Cicero, A.F.2
Gaddi, A.3
-
50
-
-
19944433033
-
Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: A randomized, placebo-controlled trial
-
De Jager J, Kooy A, Lehert P, et al. Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo-controlled trial. J Intern Med 2005;257:100-9
-
(2005)
J Intern Med
, vol.257
, pp. 100-109
-
-
De Jager, J.1
Kooy, A.2
Lehert, P.3
-
51
-
-
29744457748
-
Diabetes treatments have differential effects on non-traditional cardiovascular risk factors
-
Fonseca V, Theuma P, Mudaliar S, et al. Diabetes treatments have differential effects on non-traditional cardiovascular risk factors. J Diabetes Complications 2006;20:14-20
-
(2006)
J Diabetes Complications
, vol.20
, pp. 14-20
-
-
Fonseca, V.1
Theuma, P.2
Mudaliar, S.3
-
52
-
-
0035992811
-
Glitazones: Clinical effects and molecular mechanisms
-
Stumvoll M, Haring HU. Glitazones: clinical effects and molecular mechanisms. Ann Med 2002;34(3):217-24
-
(2002)
Ann Med
, vol.34
, Issue.3
, pp. 217-224
-
-
Stumvoll, M.1
Haring, H.U.2
-
53
-
-
65649116367
-
Transcriptional control of vascular smooth muscle cell proliferation by peroxisome proliferator-activated receptor-gamma: Therapeutic implications for cardiovascular diseases
-
Gizard F, Bruemmer D. Transcriptional control of vascular smooth muscle cell proliferation by peroxisome proliferator-activated receptor-gamma: therapeutic implications for cardiovascular diseases. PPAR Res 2008;2008:429123
-
(2008)
PPAR Res
, vol.2008
, pp. 429123
-
-
Gizard, F.1
Bruemmer, D.2
-
54
-
-
33846069095
-
Reprint of: Thiazolidinediones for the treatment of type 2 diabetes
-
Elte JWF, Blickle JF. Reprint of: thiazolidinediones for the treatment of type 2 diabetes. Eur J Intern Med 2011;18(1):18-25
-
(2011)
Eur J Intern Med
, vol.18
, Issue.1
, pp. 18-25
-
-
Jwf, E.1
Blickle, J.F.2
-
55
-
-
20444495375
-
Improvement of cardiovascular risk markers by pioglitazone is independent from glycemic control: Results from the pioneer study
-
Pfutzner A, Marx N, Lubben G, et al. Improvement of cardiovascular risk markers by pioglitazone is independent from glycemic control: results from the pioneer study. J Am Coll Cardiol 2005;45:1925-31 .
-
(2005)
J Am Coll Cardiol
, vol.45
, pp. 1925-1931
-
-
Pfutzner, A.1
Marx, N.2
Lubben, G.3
-
56
-
-
24144470455
-
Rapid effects of rosiglitazone treatment on endothelial function and inflammatory biomarkers
-
Hetzel J, Balletshofer B, Rittig K, et al. Rapid effects of rosiglitazone treatment on endothelial function and inflammatory biomarkers. Arterioscler Thromb Vasc Biol 2005;25:1804-9
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1804-1809
-
-
Hetzel, J.1
Balletshofer, B.2
Rittig, K.3
-
57
-
-
22144441406
-
Thiazolidinediones inhibit TNFalpha induction of PAI-1 independent of PPARgamma activation
-
Liu HB, Hu YS, Medcalf RL, et al. Thiazolidinediones inhibit TNFalpha induction of PAI-1 independent of PPARgamma activation. Biochem Biophys Res Commun 2005;334:30-7
-
(2005)
Biochem Biophys Res Commun
, vol.334
, pp. 30-37
-
-
Liu, H.B.1
Hu, Y.S.2
Medcalf, R.L.3
-
58
-
-
4444363344
-
Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes
-
Akbiyik F, Ray DM, Gettings KF, et al. Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes. Blood 2004;104(5):1361-8
-
(2004)
Blood
, vol.104
, Issue.5
, pp. 1361-1368
-
-
Akbiyik, F.1
Ray, D.M.2
Gettings, K.F.3
-
59
-
-
28444438100
-
Pioglitazone protects against thrombosis in a mouse model of obesity and insulin resistance
-
Bodary PF, Vargas FB, King SA, et al. Pioglitazone protects against thrombosis in a mouse model of obesity and insulin resistance. J Thromb Haemost 2005;3(10):2149-53
-
(2005)
J Thromb Haemost
, vol.3
, Issue.10
, pp. 2149-2153
-
-
Bodary, P.F.1
Vargas, F.B.2
King, S.A.3
-
60
-
-
13844272374
-
The effects of PPAR-gamma ligand pioglitazone on platelet aggregation and arterial thrombus formation
-
Li D, Chen K, Sinha N, et al. The effects of PPAR-gamma ligand pioglitazone on platelet aggregation and arterial thrombus formation. Cardiovasc Res 2005;65(4):907-12
-
(2005)
Cardiovasc Res
, vol.65
, Issue.4
, pp. 907-912
-
-
Li, D.1
Chen, K.2
Sinha, N.3
-
61
-
-
26244453309
-
Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial in macroVascular Events): A randomized controlled trial
-
Dormandy JA, Charbonnel B, Eckland DJ, et al. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomized controlled trial. Lancet 2005;366:1279-89 .
-
(2005)
Lancet
, vol.366
, pp. 1279-1289
-
-
Dormandy, J.A.1
Charbonnel, B.2
Eckland, D.J.3
-
62
-
-
2342461706
-
Inhibitory effect of pioglitazone on expression of adhesion molecules on neutrophils and endothelial cells
-
Imamoto E, Yoshida N, Uchiyama K, et al. Inhibitory effect of pioglitazone on expression of adhesion molecules on neutrophils and endothelial cells. Biofactors 1920;1:37-47
-
(1920)
Biofactors
, vol.1
, pp. 37-47
-
-
Imamoto, E.1
Yoshida, N.2
Uchiyama, K.3
-
63
-
-
24144448954
-
Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms
-
Polikandriotis JA, Mazzella LJ, Rupnow HL, Hart CM. Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms. Arterioscler Thromb Vasc Biol 2005;25:1810-16
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1810-1816
-
-
Polikandriotis, J.A.1
Mazzella, L.J.2
Rupnow, H.L.3
Hart, C.M.4
-
64
-
-
33745013392
-
Effects of pioglitazone on lipid and lipoprotein profiles in patients with type 2 diabetes and dyslipidaemia after treatment conversion from rosiglitazone while continuing stable statin therapy
-
Berhanu P, Kipnes MS, Khan MA, et al. Effects of pioglitazone on lipid and lipoprotein profiles in patients with type 2 diabetes and dyslipidaemia after treatment conversion from rosiglitazone while continuing stable statin therapy. Diab Vasc Dis Res 2006;3:39-44
-
(2006)
Diab Vasc Dis Res
, vol.3
, pp. 39-44
-
-
Berhanu, P.1
Kipnes, M.S.2
Khan, M.A.3
-
65
-
-
33644826717
-
Effects of pioglitazone on lipoproteins, inflammatory markers and adipokines in nondiabetic patients with metabolic syndrome
-
Szapary PO, Bloedon LT, Samaha FF, et al. Effects of pioglitazone on lipoproteins, inflammatory markers and adipokines in nondiabetic patients with metabolic syndrome. Arterioscler Thromb Vasc Biol 2006;26:182-8
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 182-188
-
-
Szapary, P.O.1
Bloedon, L.T.2
Samaha, F.F.3
-
66
-
-
0038509116
-
Effects of C-reactive protein on the release of von Willebrand factor, E-selectin, thrombomodulin and intercellular adhesion molecule-1 from human umbilical vein endothelial cells
-
Blann AD, Lip GY. Effects of C-reactive protein on the release of von Willebrand factor, E-selectin, thrombomodulin and intercellular adhesion molecule-1 from human umbilical vein endothelial cells. Blood Coagul Fibrinolysis 2003;14:335-40
-
(2003)
Blood Coagul Fibrinolysis
, vol.14
, pp. 335-340
-
-
Blann, A.D.1
Lip, G.Y.2
-
67
-
-
38449105442
-
Insulin resistance and thrombogenesis: Recent insights and therapeutic implications
-
Baalbaki HA, Bell DS. Insulin resistance and thrombogenesis: recent insights and therapeutic implications. Endocr Pract 2007;13:679-86
-
(2007)
Endocr Pract
, vol.13
, pp. 679-686
-
-
Baalbaki, H.A.1
Bell, D.S.2
-
68
-
-
0028032417
-
Potentiation of insulin stimulation of phosphatidylinositol 3-kinase by thiazolidinedione-derived antidiabetic agents in Chinese hamster ovary cells expressing human insulin receptors and L6 myotubes
-
Zhang B, Szalkowski D, Diaz E, et al. Potentiation of insulin stimulation of phosphatidylinositol 3-kinase by thiazolidinedione-derived antidiabetic agents in Chinese hamster ovary cells expressing human insulin receptors and L6 myotubes. J Biol Chem 1994;269:25735-41
-
(1994)
J Biol Chem
, vol.269
, pp. 25735-25741
-
-
Zhang, B.1
Szalkowski, D.2
Diaz, E.3
-
69
-
-
36549014601
-
Insulin facilitates monocyte migration: A possible link to tissue inflammation in insulin-resistance
-
Kappert K, Meyborg H, Clemenz M, et al. Insulin facilitates monocyte migration: a possible link to tissue inflammation in insulin-resistance. Biochem Biophys Res Commun 2008;365:503-8
-
(2008)
Biochem Biophys Res Commun
, vol.365
, pp. 503-508
-
-
Kappert, K.1
Meyborg, H.2
Clemenz, M.3
-
70
-
-
1842433830
-
Long-term glycaemic control with pioglitazone in patients with type 2 diabetes
-
Campbell IW. Long-term glycaemic control with pioglitazone in patients with type 2 diabetes. Int J Clin Pract 2004;58:192-200
-
(2004)
Int J Clin Pract
, vol.58
, pp. 192-200
-
-
Campbell, I.W.1
-
71
-
-
39549087229
-
2-year effects of pioglitazone add-on to sulfonylurea or metformin on oral glucose tolerance in patients with type 2 diabetes
-
Seufert J, Urquhart R. 2-year effects of pioglitazone add-on to sulfonylurea or metformin on oral glucose tolerance in patients with type 2 diabetes. Diabetes Res Clin Pract 2008;79:453-60
-
(2008)
Diabetes Res Clin Pract
, vol.79
, pp. 453-460
-
-
Seufert, J.1
Urquhart, R.2
-
72
-
-
42149107512
-
Role of smooth muscle cells in the initiation and early progression of atherosclerosis
-
Doran AC, Meller N, McNamara CA. Role of smooth muscle cells in the initiation and early progression of atherosclerosis. Arterioscler Thromb Vasc Biol 2008;28:812-19
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 812-819
-
-
Doran, A.C.1
Meller, N.2
McNamara, C.A.3
-
73
-
-
0035943010
-
Pioglitazone enhances cytokine-induced apoptosis in vascular smooth muscle cells and reduces intimal hyperplasia
-
Aizawa Y, Kawabe J, Hasebe N, et al. Pioglitazone enhances cytokine-induced apoptosis in vascular smooth muscle cells and reduces intimal hyperplasia. Circulation 2001;104:455-60
-
(2001)
Circulation
, vol.104
, pp. 455-460
-
-
Aizawa, Y.1
Kawabe, J.2
Hasebe, N.3
-
74
-
-
34247887682
-
Effects of pioglitazone on fasting and postprandial levels of lipid and hemostatic variables in overweight non-diabetic patients with coronary artery disease
-
Mieszczanska H, Kaba NK, Francis CW, et al. Effects of pioglitazone on fasting and postprandial levels of lipid and hemostatic variables in overweight non-diabetic patients with coronary artery disease. J Thromb Haemost 2007;5:942-9
-
(2007)
J Thromb Haemost
, vol.5
, pp. 942-949
-
-
Mieszczanska, H.1
Kaba, N.K.2
Francis, C.W.3
-
75
-
-
35348876837
-
Review of the pleiotropic effects of peroxisome proliferatoractivated receptor gamma agonists on platelet function
-
Borchert M, Schondorf T, Lubben G, et al. Review of the pleiotropic effects of peroxisome proliferatoractivated receptor gamma agonists on platelet function. Diabetes Technol Ther 2007;9:410-20
-
(2007)
Diabetes Technol Ther
, vol.9
, pp. 410-420
-
-
Borchert, M.1
Schondorf, T.2
Lubben, G.3
-
76
-
-
39049126602
-
Comparative effects of rosiglitazone and pioglitazone on fasting and postprandial low-density lipoprotein size and subclasses in patients with type-2 diabetes
-
Berneis K, Rizzo M, Stettler C, et al. Comparative effects of rosiglitazone and pioglitazone on fasting and postprandial low-density lipoprotein size and subclasses in patients with type-2 diabetes. Expert Opin Pharmacother 2008;9:343-9
-
(2008)
Expert Opin Pharmacother
, vol.9
, pp. 343-349
-
-
Berneis, K.1
Rizzo, M.2
Stettler, C.3
-
77
-
-
52249118511
-
The differential effects of thiazolidindiones on atherogenic dyslipidemia in type-2 diabetes: What is the clinical significance?
-
Rizzo M, Christ ER, Rini GB, et al. The differential effects of thiazolidindiones on atherogenic dyslipidemia in type-2 diabetes: what is the clinical significance ? Expert Opin Pharmacother 2008;9:2295-303
-
(2008)
Expert Opin Pharmacother
, vol.9
, pp. 2295-2303
-
-
Rizzo, M.1
Christ, E.R.2
Rini, G.B.3
-
78
-
-
41649084422
-
Comparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: The PERISCOPE randomized controlled trial
-
Nissen SE, Nicholls SJ, Wolski K, et al. Comparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: the PERISCOPE randomized controlled trial. JAMA 2008;299:1561-73
-
(2008)
JAMA
, vol.299
, pp. 1561-1573
-
-
Nissen, S.E.1
Nicholls, S.J.2
Wolski, K.3
-
79
-
-
34548590934
-
Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: A meta-analysis of randomized trials
-
Lincoff AM, Wolski K, Nicholls SJ, Nissen SE. Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized trials. JAMA 2007;298:1180-8
-
(2007)
JAMA
, vol.298
, pp. 1180-1188
-
-
Lincoff, A.M.1
Wolski, K.2
Nicholls, S.J.3
Nissen, S.E.4
-
80
-
-
54049110924
-
Future perspectives on glucagon-like peptide- 1 diabetes and cardiovascular risk
-
Mannucci E, Rotella CM. Future perspectives on glucagon-like peptide- 1 diabetes and cardiovascular risk. Nutr Metab Cardiovasc Dis 2008;18:639-45
-
(2008)
Nutr Metab Cardiovasc Dis
, vol.18
, pp. 639-645
-
-
Mannucci, E.1
Rotella, C.M.2
-
81
-
-
79960320108
-
Review of the safety and efficacy of linagliptin as add on therapy to metformin in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled study
-
Rendell M, Chrysant SG. Review of the safety and efficacy of linagliptin as add on therapy to metformin in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled study. Postgrad Med 2011;23:183-6
-
(2011)
Postgrad Med
, vol.23
, pp. 183-186
-
-
Rendell, M.1
Chrysant, S.G.2
-
82
-
-
77953108350
-
A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetes
-
Frederich R, Alexander JH, Fiedorek ET, et al. A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetes. Postgrad Med 2010;122:16-27
-
(2010)
Postgrad Med
, vol.122
, pp. 16-27
-
-
Frederich, R.1
Alexander, J.H.2
Fiedorek, E.T.3
-
83
-
-
43249089631
-
Cardioprotective and vasodilatory action of glucagon-like peptide1 receptor-dependent and independent pathways
-
Ban K, Noyan-Ashraf MH, Hoefer J, et al. Cardioprotective and vasodilatory action of glucagon-like peptide1 receptor-dependent and independent pathways. Circulation 2008;117:2340-50
-
(2008)
Circulation
, vol.117
, pp. 2340-2350
-
-
Ban, K.1
Noyan-Ashraf, M.H.2
Hoefer, J.3
-
84
-
-
70349319712
-
Glucose lowering and antidiabetogenic effects of incretin-based therapies: GLP-1 analogues and DPP-4 inhibitors
-
Rizzo M, Rizvi AA, Spinas GA, et al. Glucose lowering and antidiabetogenic effects of incretin-based therapies: GLP-1 analogues and DPP-4 inhibitors. Expert Opin Investig Drugs 2009;18:1495-503
-
(2009)
Expert Opin Investig Drugs
, vol.18
, pp. 1495-1503
-
-
Rizzo, M.1
Rizvi, A.A.2
Spinas, G.A.3
-
85
-
-
77958195997
-
The oral dipeptidyl peptidase-4 inhibitor sitagliptin increases circulating endothelial progenitor cells in patients with type 2 diabetes: Possible role of stromal-derived factor-1alpha
-
Fadini GP, Boscaro E, Albiero M, et al. The oral dipeptidyl peptidase-4 inhibitor sitagliptin increases circulating endothelial progenitor cells in patients with type 2 diabetes: possible role of stromal-derived factor-1alpha. Diabetes Care 2010;33:1607-9
-
(2010)
Diabetes Care
, vol.33
, pp. 1607-1609
-
-
Fadini, G.P.1
Boscaro, E.2
Albiero, M.3
-
86
-
-
77953182696
-
Assessing the cardio-cerebrovascular safety of vildagliptin: Meta-analysis of adjudicated events from a large phase III type 2 diabetes population
-
Schweizer A, Dejager S, Foley JE, et al. Assessing the cardio-cerebrovascular safety of vildagliptin: meta-analysis of adjudicated events from a large phase III type 2 diabetes population. Diabetes Obes Metab 2010;12:485-94 .
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 485-494
-
-
Schweizer, A.1
Dejager, S.2
Foley, J.E.3
-
87
-
-
12744269196
-
Adiponectin and future coronary heart disease events among men with type 2 diabetes
-
Schulze MB, Shai I, Rimm EB, et al. Adiponectin and future coronary heart disease events among men with type 2 diabetes. Diabetes 2005;54:534-9
-
(2005)
Diabetes
, vol.54
, pp. 534-539
-
-
Schulze, M.B.1
Shai, I.2
Rimm, E.B.3
-
88
-
-
34248155376
-
Caveolin-1 triggers T-cell activation via CD26 in association with CARMA1
-
Ohnuma K, Uchiyama M, Yamochi T, et al. Caveolin-1 triggers T-cell activation via CD26 in association with CARMA1. J Biol Chem 2007;282:10117-31
-
(2007)
J Biol Chem
, vol.282
, pp. 10117-10131
-
-
Ohnuma, K.1
Uchiyama, M.2
Yamochi, T.3
-
89
-
-
77951168113
-
Genetic deletion or pharmacological inhibition of dipeptidyl peptidase-4 improves cardiovascular outcomes after myocardial infarction in mice
-
Sauve M, Ban K, Momen MA, et al. Genetic deletion or pharmacological inhibition of dipeptidyl peptidase-4 improves cardiovascular outcomes after myocardial infarction in mice. Diabetes 2010;59:1063-73
-
(2010)
Diabetes
, vol.59
, pp. 1063-1073
-
-
Sauve, M.1
Ban, K.2
Mikati, M.A..3
-
90
-
-
77951934948
-
DPP-4 inhibition by sitagliptin improves the myocardial response to dobutamine stress and mitigates stunning in a pilot study of patients with coronary artery disease
-
Read PA, Khan FZ, Heck PM, et al. DPP-4 inhibition by sitagliptin improves the myocardial response to dobutamine stress and mitigates stunning in a pilot study of patients with coronary artery disease. Circ Cardiovasc Imaging 2010;3:195-201
-
(2010)
Circ Cardiovasc Imaging
, vol.3
, pp. 195-201
-
-
Read, P.A.1
Khan, F.Z.2
Heck, P.M.3
-
91
-
-
79959966874
-
Pre-treatment with a DPP-4 inhibitor is infarct sparing in hearts from obese, pre-diabetic rats
-
Huisamen B, Genis A, Marais E, Lochner A. Pre-treatment with a DPP-4 inhibitor is infarct sparing in hearts from obese, pre-diabetic rats. Cardiovasc Drug Ther 2010;25:13-20
-
(2010)
Cardiovasc Drug Ther
, vol.25
, pp. 13-20
-
-
Huisamen, B.1
Genis, A.2
Marais, E.3
Lochner, A.4
-
92
-
-
2442482515
-
Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels and reduces glucagons levels in type 2 diabetes
-
Ahren B, Landin-Olsson M, Jansson P-A, et al. Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels and reduces glucagons levels in type 2 diabetes. J Clin Endocrinol Metab 2004;89:2078-84
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 2078-2084
-
-
Ahren, B.1
Landin-Olsson, M.2
Jansson, P.-A.3
-
93
-
-
65549109984
-
Long-term 2 year safety and efficacy of vildagliptin compared with rosiglitazone in drug-naive patients with type 2 diabetes mellitus
-
Rosenstock J, Niggli M, Maldonado-Lutomirsky M. Long-term 2 year safety and efficacy of vildagliptin compared with rosiglitazone in drug-naive patients with type 2 diabetes mellitus. Diabetes Obes Metab 2009;11:571-8
-
(2009)
Diabetes Obes Metab
, vol.11
, pp. 571-578
-
-
Rosenstock, J.1
Niggli, M.2
Maldonado-Lutomirsky, M.3
-
94
-
-
37349054435
-
Efficacy and tolerability of vildagliptin vs Pioglitazone when added to metformin: A 24-week, randomized, double-blind study
-
Bolli G, Dotta F, Rochette E, et al. Efficacy and tolerability of vildagliptin vs Pioglitazone when added to metformin: a 24-week, randomized, double-blind study. Diabetes Obes Metab 2008;10:82-90
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 82-90
-
-
Bolli, G.1
Dotta, F.2
Rochette, E.3
-
95
-
-
34248223285
-
Biology of incretins: GLP-1 and GIP
-
Aggio LL, Drucker DJ. Biology of incretins: GLP-1 and GIP. Gastroenterology 2007;132:2131-57
-
(2007)
Gastroenterology
, vol.132
, pp. 2131-2157
-
-
Aggio, L.L.1
Drucker, D.J.2
-
96
-
-
84862027177
-
Vildagliptin inhibits oxidative stress and vascular damage in streptozotocin-induced diabetic rats
-
Yamagishi S, Maeda S, Matsui T. Vildagliptin inhibits oxidative stress and vascular damage in streptozotocin-induced diabetic rats. Int J Cardiol 2012;158(1):171-3
-
(2012)
Int J Cardiol
, vol.158
, Issue.1
, pp. 171-173
-
-
Yamagishi, S.1
Maeda, S.2
Matsui, T.3
-
97
-
-
9444249032
-
The dipeptidyl peptidase IV inhibitor NVP-LAF237 improves metabolic control in diabetic and nondiabetic cynomolgus monkeys [abstract 1391-P]
-
Dardik B, Schwartzkopf C, Stevens D, et al. The dipeptidyl peptidase IV inhibitor NVP-LAF237 improves metabolic control in diabetic and nondiabetic cynomolgus monkeys [abstract 1391-P]. Diabetes 2003;52(Suppl 1):A322
-
(2003)
Diabetes
, vol.52
, Issue.SUPPL. 1
-
-
Dardik, B.1
Schwartzkopf, C.2
Stevens, D.3
-
98
-
-
23044487247
-
Improved meal-related beta-cell function and insulin sensitivity by the dipeptidyl peptidase-IV inhibitor vildagliptin in metformin-treated patients with type 2 diabetes over 1 year
-
Ahren B, Foley JE, Pacin G, Schweizer A. Improved meal-related beta-cell function and insulin sensitivity by the dipeptidyl peptidase-IV inhibitor vildagliptin in metformin-treated patients with type 2 diabetes over 1 year. Diabetes Care 2005;28:1936-40
-
(2005)
Diabetes Care
, vol.28
, pp. 1936-1940
-
-
Ahren, B.1
Foley, J.E.2
Pacin, G.3
Schweizer, A.4
|