Gypenosides induce apoptosis by Ca2+ overload mediated by endoplasmic-reticulum and store-operated Ca2+ channels in human hepatoma cells

Cancer Biotherapy and Radiopharmaceuticals

Volumn 28, Issue 4, 2013, Pages 320-326

  Sun, Da Peng ^a,b   Li, Xiao Xi ^a   Liu, Xin Li ^a   Zhao, Dan ^a   Qiu, Feng Qi ^a   Li, Yan ^a   Ma, Ping ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b JINZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Calcium ion; Cell apoptosis; Gypenosides; Hepatocellular carcinoma; HepG2 cells

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; 3,4,5 TRIMETHOXYBENZOIC ACID 8 (DIETHYLAMINO)OCTYL ESTER; CALCIUM ION; EGTAZIC ACID; GYPENOSIDE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; THAPSIGARGIN; 2-AMINOETHOXYDIPHENYL BORATE; 8-(N,N-DIETHYLAMINO)OCTYL-3,4,5-TRIMETHOXYBENZOATE; ANTINEOPLASTIC AGENT; BORON DERIVATIVE; CALCIUM; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CHELATING AGENT; ENZYME INHIBITOR; GALLIC ACID; PLANT EXTRACT;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; ENDOPLASMIC RETICULUM; EXTRACELLULAR CALCIUM; HEPATOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RECEPTOR UPREGULATION; ANALOGS AND DERIVATIVES; CELL SURVIVAL; CHEMICALLY INDUCED; DOWN REGULATION; DRUG EFFECTS; GYNOSTEMMA; HEPG2 CELL LINE; METABOLISM; NECROSIS; UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BORON COMPOUNDS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CELL SURVIVAL; CHELATING AGENTS; DOWN-REGULATION; EGTAZIC ACID; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; GALLIC ACID; GYNOSTEMMA; HEP G2 CELLS; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; NECROSIS; PLANT EXTRACTS; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; THAPSIGARGIN; UP-REGULATION;

EID: 84877848278     PISSN: 10849785     EISSN: 15578852     Source Type: Journal    
DOI: 10.1089/cbr.2012.1327     Document Type: Article

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