The molecular mechanism of gypenosides-induced G1 growth arrest of rat hepatic stellate cells

Journal of Ethnopharmacology

Volumn 117, Issue 2, 2008, Pages 309-317

  Chen, Ming Ho ^a,b,c   Chen, Shu Hsin ^c   Wang, Qwa Fun ^a,b,c   Chen, Jung Chou ^b   Chang, De Ching ^d   Hsu, Shih Lan ^e   Chen, Ching Hsein ^c   Sheue, Chiou Rong ^c   Liu, Yi Wen ^c  

^a CHIA YI CHRISTIAN HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^d NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

^e TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Anti proliferation; Cyclin D; Gypenosides; p70S6K; PDGF; Rat hepatic stellate cells

Indexed keywords

CYCLIN D1; CYCLIN D3; GYPENOSIDE; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; S6 KINASE; TRYPAN BLUE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL COUNT; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL GROWTH; CELL ISOLATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG INHIBITION; FLOW CYTOMETRY; GYNOSTEMMA PENTAPHYLLUM; LIVER CELL; LIVER FIBROSIS; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; STAINING; STELLATE CELL; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANNEXIN A5; BLOTTING, WESTERN; CELL CYCLE; CELL PROLIFERATION; CELL SEPARATION; CYCLIN D1; CYCLINS; FIBROSIS; G1 PHASE; GYNOSTEMMA; HEPATOCYTES; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; PLANT EXTRACTS; POWDERS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION;

GYNOSTEMMA PENTAPHYLLUM; RATTUS;

EID: 41949089996     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2008.02.009     Document Type: Article

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