Extracellular proteases are key mediators of Staphylococcus aureus virulence via the global modulation of virulence-determinant stability

MicrobiologyOpen

Volumn 2, Issue 1, 2013, Pages 18-34

  Kolar, Stacey L ^a   Antonio Ibarra, J ^b   Rivera, Frances E ^a   Mootz, Joe M ^b   Davenport, Jessica E ^a   Stevens, Stanley M ^a   Horswill, Alexander R ^b   Shaw, Lindsey N ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Pathogenesis; Protease; Proteolysis; Virulence determinant

Indexed keywords

POLYPEPTIDE ANTIBIOTIC AGENT; PROTEINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BLOOD; COMMUNITY ASSOCIATED METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; COMMUNITY ASSOCIATED METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUSINFECTION; CONTROLLED STUDY; ENZYME RELEASE; HUMAN; HUMAN CELL; LEUKOCYTE; MEDIATOR; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MORBIDITY; MORTALITY; MOUSE; NONHUMAN; PATHOGENESIS; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEOMICS; SKIN ABSCESS;

ANIMALS; CULTURE MEDIA; DISEASE MODELS, ANIMAL; FEMALE; GENE KNOCKOUT TECHNIQUES; HUMANS; LEUKOCYTES; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICE; PEPTIDE HYDROLASES; PHAGOCYTOSIS; PROTEIN STABILITY; PROTEOLYSIS; STAPHYLOCOCCAL INFECTIONS; SURVIVAL ANALYSIS; VIRULENCE; VIRULENCE FACTORS;

EID: 84877837706     PISSN: None     EISSN: 20458827     Source Type: Journal    
DOI: 10.1002/mbo3.55     Document Type: Article

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