-
1
-
-
0033653973
-
Demography of longevity: past, present, and future trends
-
Wilmoth J.R. Demography of longevity: past, present, and future trends. Experimental Gerontology 2000, 35:1111-1129.
-
(2000)
Experimental Gerontology
, vol.35
, pp. 1111-1129
-
-
Wilmoth, J.R.1
-
2
-
-
0030619342
-
Doubling of world population unlikely
-
Lutz W., Sanderson W., Scherbov S. Doubling of world population unlikely. Nature 1997, 387:803-805.
-
(1997)
Nature
, vol.387
, pp. 803-805
-
-
Lutz, W.1
Sanderson, W.2
Scherbov, S.3
-
3
-
-
16344394830
-
The role of public health improvements in health advances: the twentieth-century United States
-
Cutler D., Miller G. The role of public health improvements in health advances: the twentieth-century United States. Demography 2005, 42:1-22.
-
(2005)
Demography
, vol.42
, pp. 1-22
-
-
Cutler, D.1
Miller, G.2
-
4
-
-
80052308338
-
Clinical and economic outcomes of liberal versus selective drug-eluting stent use: insights from temporal analysis of the multicenter Evaluation of Drug Eluting Stents and Ischemic Events (EVENT) registry
-
Venkitachalam L., Lei Y., Stolker J.M., Mahoney E.M., Amin A.P., Lindsey J.B., et al. Clinical and economic outcomes of liberal versus selective drug-eluting stent use: insights from temporal analysis of the multicenter Evaluation of Drug Eluting Stents and Ischemic Events (EVENT) registry. Circulation 2011, 124:1028-1037.
-
(2011)
Circulation
, vol.124
, pp. 1028-1037
-
-
Venkitachalam, L.1
Lei, Y.2
Stolker, J.M.3
Mahoney, E.M.4
Amin, A.P.5
Lindsey, J.B.6
-
5
-
-
84877795476
-
-
NHS National Statistics. Prescriptions dispensed in the community statistics for 1997 to 2007: England. ISBN: 978-1-84636-223-1
-
NHS National Statistics. Prescriptions dispensed in the community statistics for 1997 to 2007: England. ISBN: 978-1-84636-223-1; 2008.
-
(2008)
-
-
-
6
-
-
84877814388
-
-
editors. Social trends 34. Published by London: TSO. ISBN 0 11 621732
-
Summerfield C, Babb P, editors. Social trends 34. Published by London: TSO. ISBN 0 11 621732 4; 2004.
-
(2004)
, vol.4
-
-
Summerfield, C.1
Babb, P.2
-
7
-
-
78649233984
-
Consequences of health trends and medical innovation for the future elderly
-
Health affairs - web exclusive available at
-
Goldman DP, Shang B, Bhattacharya J, Garber AM, Hurd M, Joyce GF et al. Consequences of health trends and medical innovation for the future elderly. Health affairs - web exclusive available at; 2005. http://content.healthaffairs.org/.
-
(2005)
-
-
Goldman, D.P.1
Shang, B.2
Bhattacharya, J.3
Garber, A.M.4
Hurd, M.5
Joyce, G.F.6
-
11
-
-
0000055057
-
Pleiotropy, natural selection, and the evolution of senescence
-
Williams G.C. Pleiotropy, natural selection, and the evolution of senescence. Evolution 1957, 11:398-411.
-
(1957)
Evolution
, vol.11
, pp. 398-411
-
-
Williams, G.C.1
-
12
-
-
0031150170
-
The effects of reproduction on longevity and fertility in male Drosophila melanogaster
-
Prowse Partridge
-
Prowse, Partridge The effects of reproduction on longevity and fertility in male Drosophila melanogaster. Journal of Insect Physiology 1997, 43:501-512.
-
(1997)
Journal of Insect Physiology
, vol.43
, pp. 501-512
-
-
-
13
-
-
0017782437
-
Evolution of ageing
-
Kirkwood T.B.L. Evolution of ageing. Nature 1977, 270:301-304.
-
(1977)
Nature
, vol.270
, pp. 301-304
-
-
Kirkwood, T.B.L.1
-
14
-
-
45449102065
-
Outbreeding alleviates senescence in hermaphroditic snails as expected from the mutation-accumulation theory
-
Escobar J.S., Jarne P., Charmantier A., David P. Outbreeding alleviates senescence in hermaphroditic snails as expected from the mutation-accumulation theory. Current Biology 2008, 18:906-910.
-
(2008)
Current Biology
, vol.18
, pp. 906-910
-
-
Escobar, J.S.1
Jarne, P.2
Charmantier, A.3
David, P.4
-
15
-
-
0036808642
-
Evolution of late-life mortality in Drosophila melanogaster
-
Rose M.R. Evolution of late-life mortality in Drosophila melanogaster. Evolution 2002, 56:1982-1991.
-
(2002)
Evolution
, vol.56
, pp. 1982-1991
-
-
Rose, M.R.1
-
16
-
-
78651294960
-
The heat dissipation limit theory and evolution of life histories in endotherms - time to dispose of the disposable soma theory?
-
Speakman J.R., Król E. The heat dissipation limit theory and evolution of life histories in endotherms - time to dispose of the disposable soma theory?. Integrative and Comparative Biology 2010, 50:793-807.
-
(2010)
Integrative and Comparative Biology
, vol.50
, pp. 793-807
-
-
Speakman, J.R.1
Król, E.2
-
17
-
-
84859492779
-
Exceptional longevity is associated with decreased reproduction
-
Tabatabaie V., Atzmon G., Rajpathak S.N., Freeman R., Barzilai N., Crandall J., et al. Exceptional longevity is associated with decreased reproduction. Aging (Albany, NY) 2011, 3:1202-1205.
-
(2011)
Aging (Albany, NY)
, vol.3
, pp. 1202-1205
-
-
Tabatabaie, V.1
Atzmon, G.2
Rajpathak, S.N.3
Freeman, R.4
Barzilai, N.5
Crandall, J.6
-
18
-
-
31144452258
-
The evolution of senescence and post-reproductive lifespan in guppies (Poecilia reticulata)
-
Reznick D., Bryant M., Holmes D. The evolution of senescence and post-reproductive lifespan in guppies (Poecilia reticulata). PLoS Biology 2006, 4:e7.
-
(2006)
PLoS Biology
, vol.4
-
-
Reznick, D.1
Bryant, M.2
Holmes, D.3
-
19
-
-
0037356456
-
Predator preference for brightly coloured males in the guppy: a viability cost for a sexually selected trait
-
Godin J.G., McDonough H.E. Predator preference for brightly coloured males in the guppy: a viability cost for a sexually selected trait. Behavioural Ecology 2003, 14:194-200.
-
(2003)
Behavioural Ecology
, vol.14
, pp. 194-200
-
-
Godin, J.G.1
McDonough, H.E.2
-
20
-
-
37849188352
-
Degeneration after sexual differentiation in Hydra and its relevance to the evolution of ageing
-
Yoshida K., Fujisawa T., Hwang J.S., Ikeo K., Gojobori T. Degeneration after sexual differentiation in Hydra and its relevance to the evolution of ageing. Gene 2006, 385:64-70.
-
(2006)
Gene
, vol.385
, pp. 64-70
-
-
Yoshida, K.1
Fujisawa, T.2
Hwang, J.S.3
Ikeo, K.4
Gojobori, T.5
-
22
-
-
79951792978
-
Maximum shell size, growth rate, and maturation age correlate with longevity in bivalve molluscs
-
Ridgway I.D., Richardson C.A., Austad S.N. Maximum shell size, growth rate, and maturation age correlate with longevity in bivalve molluscs. Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2011, 66:183-190.
-
(2011)
Journals of Gerontology Series A: Biological Sciences and Medical Sciences
, vol.66
, pp. 183-190
-
-
Ridgway, I.D.1
Richardson, C.A.2
Austad, S.N.3
-
24
-
-
0030663771
-
There is no such thing as ageing
-
Doll R. There is no such thing as ageing. British Medical Journal 1997, 315:1030-1032.
-
(1997)
British Medical Journal
, vol.315
, pp. 1030-1032
-
-
Doll, R.1
-
25
-
-
0021056471
-
A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results
-
Klass M.R. A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results. Mechanisms of Ageing and Development 1983, 22:279-286.
-
(1983)
Mechanisms of Ageing and Development
, vol.22
, pp. 279-286
-
-
Klass, M.R.1
-
26
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon C., Chang J., Gensch E., Rudner A., Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 1993, 366:461-464.
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
27
-
-
0023831256
-
A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility
-
Friedman D.B., Johnson T.E. A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. Genetics 1988, 118:75-86.
-
(1988)
Genetics
, vol.118
, pp. 75-86
-
-
Friedman, D.B.1
Johnson, T.E.2
-
28
-
-
40449142493
-
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
-
Selman C., Lingard S., Choudhury A.I., Batterham R.L., Claret M., Clements M., et al. Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice. FASEB Journal 2008, 22:807-818.
-
(2008)
FASEB Journal
, vol.22
, pp. 807-818
-
-
Selman, C.1
Lingard, S.2
Choudhury, A.I.3
Batterham, R.L.4
Claret, M.5
Clements, M.6
-
29
-
-
23844436700
-
In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans
-
Gerstbrein B., Stamatas G., Kollias N., Driscoll M. In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans. Aging Cell 2005, 4:127-137.
-
(2005)
Aging Cell
, vol.4
, pp. 127-137
-
-
Gerstbrein, B.1
Stamatas, G.2
Kollias, N.3
Driscoll, M.4
-
31
-
-
69949091182
-
Is the oxidative stress theory of aging dead?
-
Pérez V.I., Bokov A., Van Remmen H., Mele J., Ran Q., Ikeno Y., et al. Is the oxidative stress theory of aging dead?. Biochimica et Biophysica Acta 2009, 1790:1005-1014.
-
(2009)
Biochimica et Biophysica Acta
, vol.1790
, pp. 1005-1014
-
-
Pérez, V.I.1
Bokov, A.2
Van Remmen, H.3
Mele, J.4
Ran, Q.5
Ikeno, Y.6
-
32
-
-
66749126389
-
Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong?
-
Gems D., Doonan R. Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong?. Cell Cycle 2009, 8:1681-1687.
-
(2009)
Cell Cycle
, vol.8
, pp. 1681-1687
-
-
Gems, D.1
Doonan, R.2
-
33
-
-
36448969497
-
Evolutionary conservation of regulated longevity assurance mechanisms
-
McElwee J.J., Schuster E., Blanc E., Piper M.D., Thomas J.H., Patel D.S., et al. Evolutionary conservation of regulated longevity assurance mechanisms. Genome Biology 2007, 8:R132.
-
(2007)
Genome Biology
, vol.8
-
-
McElwee, J.J.1
Schuster, E.2
Blanc, E.3
Piper, M.D.4
Thomas, J.H.5
Patel, D.S.6
-
34
-
-
12344309431
-
Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling?
-
Gems D., McElwee J.J. Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling?. Mechanisms of Ageing and Development 2005, 126:381-387.
-
(2005)
Mechanisms of Ageing and Development
, vol.126
, pp. 381-387
-
-
Gems, D.1
McElwee, J.J.2
-
35
-
-
84864021710
-
Rapamycin slows aging in mice
-
Wilkinson J.E., Burmeister L., Brooks S.V., Chan C.C., Friedline S., Harrison D.E., et al. Rapamycin slows aging in mice. Aging Cell 2012, 11:675-682.
-
(2012)
Aging Cell
, vol.11
, pp. 675-682
-
-
Wilkinson, J.E.1
Burmeister, L.2
Brooks, S.V.3
Chan, C.C.4
Friedline, S.5
Harrison, D.E.6
-
36
-
-
79960925702
-
Core signaling pathways of survival/death in autophagy-related cancer networks
-
Wang S.Y., Yu Q.J., Zhang R.D., Liu B. Core signaling pathways of survival/death in autophagy-related cancer networks. International Journal of Biochemistry and Cell Biology 2011, 43:1263-1266.
-
(2011)
International Journal of Biochemistry and Cell Biology
, vol.43
, pp. 1263-1266
-
-
Wang, S.Y.1
Yu, Q.J.2
Zhang, R.D.3
Liu, B.4
-
37
-
-
45549101782
-
Cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity
-
de Magalhães J.P., Faragher R.G. Cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity. Bioessays 2008, 30:567-578.
-
(2008)
Bioessays
, vol.30
, pp. 567-578
-
-
de Magalhães, J.P.1
Faragher, R.G.2
-
38
-
-
1842789989
-
Mechanisms of cellular senescence in human and mouse cells
-
Itahana K., Campisi J., Dimri G.P. Mechanisms of cellular senescence in human and mouse cells. Biogerontology 2004, 5:1-10.
-
(2004)
Biogerontology
, vol.5
, pp. 1-10
-
-
Itahana, K.1
Campisi, J.2
Dimri, G.P.3
-
39
-
-
79551683487
-
Cellular senescence: putting the paradoxes in perspective
-
Campisi J. Cellular senescence: putting the paradoxes in perspective. Current Opinion in Genetics and Development 2011, 21:107-112.
-
(2011)
Current Opinion in Genetics and Development
, vol.21
, pp. 107-112
-
-
Campisi, J.1
-
40
-
-
77949881221
-
The senescence-associated secretory phenotype: the dark side of tumor suppression
-
Coppé J.P., Desprez P.Y., Krtolica A., Campisi J. The senescence-associated secretory phenotype: the dark side of tumor suppression. Annual Review of Pathology 2010, 5:99-118.
-
(2010)
Annual Review of Pathology
, vol.5
, pp. 99-118
-
-
Coppé, J.P.1
Desprez, P.Y.2
Krtolica, A.3
Campisi, J.4
-
41
-
-
70349229151
-
Microarray analysis of senescent vascular smooth muscle cells: a link to atherosclerosis and vascular calcification
-
Burton D.G., Giles P.J., Sheerin A.N., Smith S.K., Lawton J.J., Ostler E.L., et al. Microarray analysis of senescent vascular smooth muscle cells: a link to atherosclerosis and vascular calcification. Experimental Gerontology 2009, 44:659-665.
-
(2009)
Experimental Gerontology
, vol.44
, pp. 659-665
-
-
Burton, D.G.1
Giles, P.J.2
Sheerin, A.N.3
Smith, S.K.4
Lawton, J.J.5
Ostler, E.L.6
-
42
-
-
80855138775
-
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
-
Baker D.J. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 2011, 479:232-236.
-
(2011)
Nature
, vol.479
, pp. 232-236
-
-
Baker, D.J.1
-
43
-
-
84876268693
-
Resistance to genotoxic stresses in arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype?
-
[Epub ahead of print]
-
Ungvari Z., Sosnowska D., Mason J.B., Gruber H., Lee S.W., Schwartz T.S., et al. Resistance to genotoxic stresses in arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype?. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 2012, [Epub ahead of print].
-
(2012)
Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
-
-
Ungvari, Z.1
Sosnowska, D.2
Mason, J.B.3
Gruber, H.4
Lee, S.W.5
Schwartz, T.S.6
-
44
-
-
2642586352
-
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
-
Ravikumar B., Vacher C., Berger Z., Davies J.E., Luo S., Oroz L.G., et al. Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. Nature Genetics 2004, 36:585-595.
-
(2004)
Nature Genetics
, vol.36
, pp. 585-595
-
-
Ravikumar, B.1
Vacher, C.2
Berger, Z.3
Davies, J.E.4
Luo, S.5
Oroz, L.G.6
-
45
-
-
77956305343
-
Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease
-
Spilman P. Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease. PLoS One 2010, 5:e9979.
-
(2010)
PLoS One
, vol.5
-
-
Spilman, P.1
-
46
-
-
84874678862
-
Overexpression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease
-
[Epub ahead of print]
-
Pierce A., Podlutskaya N., Halloran J.J., Hussong S.A., Lin P.Y., Burbank R., et al. Overexpression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease. Journal of Neurochemistry 2012, [Epub ahead of print].
-
(2012)
Journal of Neurochemistry
-
-
Pierce, A.1
Podlutskaya, N.2
Halloran, J.J.3
Hussong, S.A.4
Lin, P.Y.5
Burbank, R.6
-
47
-
-
79955479386
-
Consolidation and reconsolidation of contextual fear memory requires mammalian target of rapamycin-dependent translation in the dorsal hippocampus
-
Gafford G.M., Parsons R.G., Helmstetter F.J. Consolidation and reconsolidation of contextual fear memory requires mammalian target of rapamycin-dependent translation in the dorsal hippocampus. Neuroscience 2011, 182:98-104.
-
(2011)
Neuroscience
, vol.182
, pp. 98-104
-
-
Gafford, G.M.1
Parsons, R.G.2
Helmstetter, F.J.3
|