-
1
-
-
77954183132
-
Immunotherapy for sepsis-a new approach against an ancient foe
-
Hotchkiss RS, Opal S. 2010. Immunotherapy for sepsis-a new approach against an ancient foe. N. Engl. J. Med. 363:87-89.
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 87-89
-
-
Hotchkiss, R.S.1
Opal, S.2
-
2
-
-
79951947339
-
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients
-
doi:10.1186/cc10059
-
Zhang Y, Li J, Lou J, Zhou Y, Bo L, Zhu J, Zhu K, Wan X, Cai Z, Deng X. 2011. Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients. Crit. Care 15:R70. doi:10.1186/cc10059.
-
(2011)
Crit. Care
, vol.15
-
-
Zhang, Y.1
Li, J.2
Lou, J.3
Zhou, Y.4
Bo, L.5
Zhu, J.6
Zhu, K.7
Wan, X.8
Cai, Z.9
Deng, X.10
-
3
-
-
79953121419
-
Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients
-
doi:10.1186/cc10112
-
Guignant C, Lepape A, Huang X, Kherouf H, Denis L, Poitevin F, Malcus C, Chéron A, Allaouchiche B, Gueyffier F, Ayala A, Monneret G, Venet F. 2011. Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients. Crit. Care 15:R99. doi:10.1186/cc10112.
-
(2011)
Crit. Care
, vol.15
-
-
Guignant, C.1
Lepape, A.2
Huang, X.3
Kherouf, H.4
Denis, L.5
Poitevin, F.6
Malcus, C.7
Chéron, A.8
Allaouchiche, B.9
Gueyffier, F.10
Ayala, A.11
Monneret, G.12
Venet, F.13
-
4
-
-
77956403940
-
Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis
-
Brahmamdam P, Inoue S, Unsinger J, Chang KC, McDunn JE, Hotchkiss RS. 2010. Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis. J. Leukoc. Biol. 88:233-240.
-
(2010)
J. Leukoc. Biol.
, vol.88
, pp. 233-240
-
-
Brahmamdam, P.1
Inoue, S.2
Unsinger, J.3
Chang, K.C.4
McDunn, J.E.5
Hotchkiss, R.S.6
-
5
-
-
65549084772
-
PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis
-
Huang X, Venet F, Wang YL, Lepape A, Yuan Z, Chen Y, Swan R, Kherouf H, Monneret G, Chung CS, Ayala A. 2009. PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis. Proc. Natl. Acad. Sci. U. S. A. 106:6303-6308.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 6303-6308
-
-
Huang, X.1
Venet, F.2
Wang, Y.L.3
Lepape, A.4
Yuan, Z.5
Chen, Y.6
Swan, R.7
Kherouf, H.8
Monneret, G.9
Chung, C.S.10
Ayala, A.11
-
6
-
-
79959716811
-
Dosedependent effect of anti-CTLA-4 on survival in sepsis
-
Inoue S, Bo L, Bian J, Unsinger J, Chang K, Hotchkiss RS. 2011. Dosedependent effect of anti-CTLA-4 on survival in sepsis. Shock 36:38-44.
-
(2011)
Shock
, vol.36
, pp. 38-44
-
-
Inoue, S.1
Bo, L.2
Bian, J.3
Unsinger, J.4
Chang, K.5
Hotchkiss, R.S.6
-
7
-
-
4544354937
-
Blockade of 4-1BB (CD137)/4-1BB ligand interactions increases allograft survival
-
Cho HR, Kwon B, Yagita H, La S, Lee EA, Kim JE, Akiba H, Kim J, Suh JH, Vinay DS, Ju SA, Kim BS, Mittler RS, Okumura K, Kwon BS. 2004. Blockade of 4-1BB (CD137)/4-1BB ligand interactions increases allograft survival. Transpl. Int. 17:351-361.
-
(2004)
Transpl. Int.
, vol.17
, pp. 351-361
-
-
Cho, H.R.1
Kwon, B.2
Yagita, H.3
La, S.4
Lee, E.A.5
Kim, J.E.6
Akiba, H.7
Kim, J.8
Suh, J.H.9
Vinay, D.S.10
Ju, S.A.11
Kim, B.S.12
Mittler, R.S.13
Okumura, K.14
Kwon, B.S.15
-
8
-
-
23344432753
-
4-1BB (CD137) is required for rapid clearance of Listeria monocytogenes infection
-
Lee SC, Ju SA, Pack HN, Heo SK, Suh JH, Park SMB, Choi K, Kwon BS, Kim BS. 2005. 4-1BB (CD137) is required for rapid clearance of Listeria monocytogenes infection. Infect. Immun. 73:5144-5151.
-
(2005)
Infect. Immun.
, vol.73
, pp. 5144-5151
-
-
Lee, S.C.1
Ju, S.A.2
Pack, H.N.3
Heo, S.K.4
Suh, J.H.5
Park, S.M.B.6
Choi, K.7
Kwon, B.S.8
Kim, B.S.9
-
9
-
-
0036199305
-
Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells
-
Futagawa T, Akiba H, Kodama T, Takeda K, Hosoda Y, Yagita H, Okumura K. 2002. Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells. Int. Immunol. 14:275-286.
-
(2002)
Int. Immunol.
, vol.14
, pp. 275-286
-
-
Futagawa, T.1
Akiba, H.2
Kodama, T.3
Takeda, K.4
Hosoda, Y.5
Yagita, H.6
Okumura, K.7
-
10
-
-
0032535119
-
NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies
-
Melero I, Johnston JV, Shufford WW, Mittler RS, Chen L. 1998. NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies. Cell. Immunol. 190:167-172.
-
(1998)
Cell. Immunol.
, vol.190
, pp. 167-172
-
-
Melero, I.1
Johnston, J.V.2
Shufford, W.W.3
Mittler, R.S.4
Chen, L.5
-
11
-
-
28844480518
-
Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor
-
Nishimoto H, Lee SW, Hong H, Potter KG, Maeda-Yamamoto M, Kinoshita T, Kawakami Y, Mittler RS, Kwon BS, Ware CF, Croft M, Kawakami T. 2005. Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor. Blood 106:4241-4248.
-
(2005)
Blood
, vol.106
, pp. 4241-4248
-
-
Nishimoto, H.1
Lee, S.W.2
Hong, H.3
Potter, K.G.4
Maeda-Yamamoto, M.5
Kinoshita, T.6
Kawakami, Y.7
Mittler, R.S.8
Kwon, B.S.9
Ware, C.F.10
Croft, M.11
Kawakami, T.12
-
12
-
-
26844577971
-
Engagement of 4-1BB inhibits the development of experimental allergic conjunctivitis in mice
-
Fukushima A, Yamaguchi T, Ishida W, Fukata K, Mittler RS, Yagita H, Ueno H. 2005. Engagement of 4-1BB inhibits the development of experimental allergic conjunctivitis in mice. J. Immunol. 175:4897-4903.
-
(2005)
J. Immunol.
, vol.175
, pp. 4897-4903
-
-
Fukushima, A.1
Yamaguchi, T.2
Ishida, W.3
Fukata, K.4
Mittler, R.S.5
Yagita, H.6
Ueno, H.7
-
13
-
-
77956414971
-
Peripheral 4-1BB signaling negatively regulates NK cell development through IFN-γ
-
Choi BK, Kim YH, Kim CH, Kim MS, Kim KH, Oh HS, Lee MJ, Lee DK, Vinay DS, Kwon BS. 2010. Peripheral 4-1BB signaling negatively regulates NK cell development through IFN-γ. J. Immunol. 185:1404-1411.
-
(2010)
J. Immunol.
, vol.185
, pp. 1404-1411
-
-
Choi, B.K.1
Kim, Y.H.2
Kim, C.H.3
Kim, M.S.4
Kim, K.H.5
Oh, H.S.6
Lee, M.J.7
Lee, D.K.8
Vinay, D.S.9
Kwon, B.S.10
-
14
-
-
77950403194
-
CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells
-
Narazaki H, Zhu Y, Luo L, Zhu G, Chen L. 2010. CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells. Blood 115:1941-1948.
-
(2010)
Blood
, vol.115
, pp. 1941-1948
-
-
Narazaki, H.1
Zhu, Y.2
Luo, L.3
Zhu, G.4
Chen, L.5
-
15
-
-
0033954331
-
CD137 (ILA/4-1BB), expressed by primary human monocytes, induces monocyte activation and apoptosis of B lymphocytes
-
Kienzle G, von Kempis J. 2000. CD137 (ILA/4-1BB), expressed by primary human monocytes, induces monocyte activation and apoptosis of B lymphocytes. Int. Immunol. 12:73-82.
-
(2000)
Int. Immunol.
, vol.12
, pp. 73-82
-
-
Kienzle, G.1
von Kempis, J.2
-
16
-
-
0034536445
-
CD137 activation abrogates granulocyte-macrophage colony-stimulating factor-mediated anti-apoptosis in neutrophils
-
Heinisch IV, Daigle I, Knöpfli B, Simon HU. 2000. CD137 activation abrogates granulocyte-macrophage colony-stimulating factor-mediated anti-apoptosis in neutrophils. Eur. J. Immunol. 30:3441-3446.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 3441-3446
-
-
Heinisch, I.V.1
Daigle, I.2
Knöpfli, B.3
Simon, H.U.4
-
17
-
-
65449168803
-
Stimulation of the molecule 4-1BB enhances host defense against Listeria monocytogenes infection in mice by inducing rapid infiltration and activation of neutrophils and monocytes
-
Lee SC, Ju SA, Sung BH, Heo SK, Cho HR, Lee EA, Kim JD, Lee IH, Park SM, Nguyen QT, Suh JH, Kim BS. 2009. Stimulation of the molecule 4-1BB enhances host defense against Listeria monocytogenes infection in mice by inducing rapid infiltration and activation of neutrophils and monocytes. Infect. Immun. 77:2168-2176.
-
(2009)
Infect. Immun.
, vol.77
, pp. 2168-2176
-
-
Lee, S.C.1
Ju, S.A.2
Sung, B.H.3
Heo, S.K.4
Cho, H.R.5
Lee, E.A.6
Kim, J.D.7
Lee, I.H.8
Park, S.M.9
Nguyen, Q.T.10
Suh, J.H.11
Kim, B.S.12
-
18
-
-
69049118142
-
Blockade of CD137 signaling counteracts polymicrobial sepsis induced by cecal ligation and puncture
-
Nguyen QT, Ju SA, Park SM, Lee SC, Yagita H, Lee IH, Kim BS. 2009. Blockade of CD137 signaling counteracts polymicrobial sepsis induced by cecal ligation and puncture. Infect. Immun. 77:3932-3938.
-
(2009)
Infect. Immun.
, vol.77
, pp. 3932-3938
-
-
Nguyen, Q.T.1
Ju, S.A.2
Park, S.M.3
Lee, S.C.4
Yagita, H.5
Lee, I.H.6
Kim, B.S.7
-
19
-
-
0035794876
-
Differential clonal expansion of CD4 and CD8 T cells in response to 4-1BB ligation: contribution of 4-1BB during inflammatory responses
-
Takahashi C, Mittler RS, Vella AT. 2001. Differential clonal expansion of CD4 and CD8 T cells in response to 4-1BB ligation: contribution of 4-1BB during inflammatory responses. Immunol. Lett. 76:183-191.
-
(2001)
Immunol. Lett.
, vol.76
, pp. 183-191
-
-
Takahashi, C.1
Mittler, R.S.2
Vella, A.T.3
-
20
-
-
2542420995
-
Mannose-binding lectin-deficient mice are susceptible to infection with Staphylococcus aureus
-
Shi L, Takahashi K, Dundee J, Shahroor-Karni S, Thiel S, Jensenius JC, Gad F, Hamblin MR, Sastry KN, Ezekowitz RA. 2004. Mannose-binding lectin-deficient mice are susceptible to infection with Staphylococcus aureus. J. Exp. Med. 199:1379-1390.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1379-1390
-
-
Shi, L.1
Takahashi, K.2
Dundee, J.3
Shahroor-Karni, S.4
Thiel, S.5
Jensenius, J.C.6
Gad, F.7
Hamblin, M.R.8
Sastry, K.N.9
Ezekowitz, R.A.10
-
21
-
-
33646443277
-
LIGHT enhances the bactericidal activity of human monocytes and neutrophils via HVEM
-
Heo SK, Ju SA, Lee SC, Park SM, Choe SY, Kwon B, Kwon BS, Kim BS. 2006. LIGHT enhances the bactericidal activity of human monocytes and neutrophils via HVEM. J. Leukoc. Biol. 79:330-338.
-
(2006)
J. Leukoc. Biol.
, vol.79
, pp. 330-338
-
-
Heo, S.K.1
Ju, S.A.2
Lee, S.C.3
Park, S.M.4
Choe, S.Y.5
Kwon, B.6
Kwon, B.S.7
Kim, B.S.8
-
22
-
-
34548120736
-
Absence of 4-1BB increases cell influx into the peritoneal cavity in response to LPS stimulation by decreasing macrophage IL-10 levels
-
Shin HH, Lee JE, Choi HS. 2007. Absence of 4-1BB increases cell influx into the peritoneal cavity in response to LPS stimulation by decreasing macrophage IL-10 levels. FEBS Lett. 581:4355-4360.
-
(2007)
FEBS Lett.
, vol.581
, pp. 4355-4360
-
-
Shin, H.H.1
Lee, J.E.2
Choi, H.S.3
-
23
-
-
60549101332
-
Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4
-
Roger T, Froidevaux C, Le Roy D, Reymond MK, Chanson AL, Mauri D, Burns K, Riederer BM, Akira S, Calandra T. 2009. Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4. Proc. Natl. Acad. Sci. U. S. A. 106:2348-2352.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 2348-2352
-
-
Roger, T.1
Froidevaux, C.2
Le Roy, D.3
Reymond, M.K.4
Chanson, A.L.5
Mauri, D.6
Burns, K.7
Riederer, B.M.8
Akira, S.9
Calandra, T.10
-
24
-
-
28444483567
-
Relative roles of complement factor 3 and mannose-binding lectin in host defense against infection
-
Takahashi K, Shi L, Gowda LD, Ezekowitz RA. 2005. Relative roles of complement factor 3 and mannose-binding lectin in host defense against infection. Infect. Immun. 73:8188-8193.
-
(2005)
Infect. Immun.
, vol.73
, pp. 8188-8193
-
-
Takahashi, K.1
Shi, L.2
Gowda, L.D.3
Ezekowitz, R.A.4
-
25
-
-
0034669910
-
Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection
-
Takeuchi O, Hoshino K, Akira S. 2000. Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection. J. Immunol. 165:5392-5396.
-
(2000)
J. Immunol.
, vol.165
, pp. 5392-5396
-
-
Takeuchi, O.1
Hoshino, K.2
Akira, S.3
-
26
-
-
18344371541
-
Toll-like receptor 4 deficiency and acute pancreatitis act similarly in reducing host defense during murine Escherichia coli peritonitis
-
van Westerloo DJ, Weijer S, Bruno MJ, de Vos AF, Van't Veer C, van der Poll T. 2005. Toll-like receptor 4 deficiency and acute pancreatitis act similarly in reducing host defense during murine Escherichia coli peritonitis. Crit. Care Med. 33:1036-1043.
-
(2005)
Crit. Care Med.
, vol.33
, pp. 1036-1043
-
-
van Westerloo, D.J.1
Weijer, S.2
Bruno, M.J.3
de Vos, A.F.4
Van't Veer, C.5
van der Poll, T.6
-
27
-
-
62649121369
-
Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis
-
Alves-Filho JC, Freitas A, Souto FO, Spiller F, Paula-Neto H, Silva JS, Gazzinelli RT, Teixeira MM, Ferreira SH, Cunha FQ. 2009. Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis. Proc. Natl. Acad. Sci. U. S. A. 106:4018-4023.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 4018-4023
-
-
Alves-Filho, J.C.1
Freitas, A.2
Souto, F.O.3
Spiller, F.4
Paula-Neto, H.5
Silva, J.S.6
Gazzinelli, R.T.7
Teixeira, M.M.8
Ferreira, S.H.9
Cunha, F.Q.10
-
28
-
-
0037451929
-
The epidemiology of sepsis in the United States from 1979 through 2000
-
Martin GS, Mannino DM, Eaton S, Moss M. 2003. The epidemiology of sepsis in the United States from 1979 through 2000. N. Engl. J. Med. 348:1546-1554.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1546-1554
-
-
Martin, G.S.1
Mannino, D.M.2
Eaton, S.3
Moss, M.4
-
29
-
-
2442587841
-
Differential gene expression in gram-negative and gram-positive sepsis
-
Yu SL, Chen HW, Yang PC, Peck K, Tsai MH, Chen JJ, Lin FY. 2004. Differential gene expression in gram-negative and gram-positive sepsis. Am. J. Respir. Crit. Care Med. 169:1135-1143.
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
, pp. 1135-1143
-
-
Yu, S.L.1
Chen, H.W.2
Yang, P.C.3
Peck, K.4
Tsai, M.H.5
Chen, J.J.6
Lin, F.Y.7
-
30
-
-
33847408050
-
Gene expression patterns in blood leukocytes discriminate patients with acute infections
-
Ramilo O, Allman W, Chung W, Mejias A, Ardura M, Glaser C, Wittkowski KM, Piqueras B, Banchereau J, Palucka AK, Chaussabel D. 2007. Gene expression patterns in blood leukocytes discriminate patients with acute infections. Blood 109:2066-2077.
-
(2007)
Blood
, vol.109
, pp. 2066-2077
-
-
Ramilo, O.1
Allman, W.2
Chung, W.3
Mejias, A.4
Ardura, M.5
Glaser, C.6
Wittkowski, K.M.7
Piqueras, B.8
Banchereau, J.9
Palucka, A.K.10
Chaussabel, D.11
-
31
-
-
77951204279
-
The response of the host microcirculation to bacterial sepsis: does the pathogen matter? J
-
Legrand M, Klijn E, Payen D, Ince C. 2010. The response of the host microcirculation to bacterial sepsis: does the pathogen matter? J. Mol. Med. (Berl.) 88:127-133.
-
(2010)
Mol. Med. (Berl.)
, vol.88
, pp. 127-133
-
-
Legrand, M.1
Klijn, E.2
Payen, D.3
Ince, C.4
-
32
-
-
79956300649
-
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
-
Kawai T, Akira S. 2011. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34:637-650.
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
33
-
-
34249292281
-
Blockade of the 4-1BB (CD137)/4-1BBL and/or CD28/CD80/CD86 costimulatory pathways promotes corneal allograft survival in mice
-
Asai T, Choi BK, Kwon PM, Kim WY, Kim JD, Vinay DS, Gebhardt BM, Kwon BS. 2007. Blockade of the 4-1BB (CD137)/4-1BBL and/or CD28/CD80/CD86 costimulatory pathways promotes corneal allograft survival in mice. Immunology 121:349-358.
-
(2007)
Immunology
, vol.121
, pp. 349-358
-
-
Asai, T.1
Choi, B.K.2
Kwon, P.M.3
Kim, W.Y.4
Kim, J.D.5
Vinay, D.S.6
Gebhardt, B.M.7
Kwon, B.S.8
-
34
-
-
17644389199
-
TNF/TNFR family members in costimulation of T cell responses
-
Watts TH. 2005. TNF/TNFR family members in costimulation of T cell responses. Annu. Rev. Immunol. 23:23-68.
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 23-68
-
-
Watts, T.H.1
-
36
-
-
4644245852
-
CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses
-
Vinay DS, Choi BK, Bae JS, Kim WY, Gebhardt BM, Kwon BS. 2004. CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses. J. Immunol. 173:4218-4229.
-
(2004)
J. Immunol.
, vol.173
, pp. 4218-4229
-
-
Vinay, D.S.1
Choi, B.K.2
Bae, J.S.3
Kim, W.Y.4
Gebhardt, B.M.5
Kwon, B.S.6
-
37
-
-
64249112101
-
4-1BB functions as a survival factor in dendritic cells
-
Choi BK, Kim YH, Kwon PM, Lee SC, Kang SW, Kim MS, Lee MJ, Kwon BS. 2009. 4-1BB functions as a survival factor in dendritic cells. J. Immunol. 182:4107-4115.
-
(2009)
J. Immunol.
, vol.182
, pp. 4107-4115
-
-
Choi, B.K.1
Kim, Y.H.2
Kwon, P.M.3
Lee, S.C.4
Kang, S.W.5
Kim, M.S.6
Lee, M.J.7
Kwon, B.S.8
|