-
1
-
-
0037448612
-
Molecular biology of the Ets family of transcription factors
-
Oikawa T, Yamada T,. Molecular biology of the Ets family of transcription factors. Gene 2003; 303: 11-34.
-
(2003)
Gene
, vol.303
, pp. 11-34
-
-
Oikawa, T.1
Yamada, T.2
-
2
-
-
0028307384
-
A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG
-
Sorensen PH, Lessnick SL, Lopez-Terrada D, et al. A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG. Nat Genet 1994; 6: 146-51.
-
(1994)
Nat Genet
, vol.6
, pp. 146-151
-
-
Sorensen, P.H.1
Lessnick, S.L.2
Lopez-Terrada, D.3
-
3
-
-
33947581390
-
The impact of translocations and gene fusions on cancer causation
-
Mitelman F, Johansson B, Mertens F,. The impact of translocations and gene fusions on cancer causation. Nat Rev Cancer 2007; 7: 233-45.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 233-245
-
-
Mitelman, F.1
Johansson, B.2
Mertens, F.3
-
4
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
Tomlins SA, Rhodes DR, Perner S, et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005; 310: 644-8.
-
(2005)
Science
, vol.310
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
-
5
-
-
70350109641
-
ETS gene fusions in prostate cancer
-
Clark JP, Cooper CS,. ETS gene fusions in prostate cancer. Nat Rev Urol 2009; 6: 429-39.
-
(2009)
Nat Rev Urol
, vol.6
, pp. 429-439
-
-
Clark, J.P.1
Cooper, C.S.2
-
7
-
-
39049150843
-
Role of the TMPRSS2-ERG gene fusion in prostate cancer
-
Tomlins SA, Laxman B, Varambally S, et al. Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia 2008; 10: 177-88.
-
(2008)
Neoplasia
, vol.10
, pp. 177-188
-
-
Tomlins, S.A.1
Laxman, B.2
Varambally, S.3
-
8
-
-
41149097040
-
A causal role for ERG in neoplastic transformation of prostate epithelium
-
Klezovitch O, Risk M, Coleman I, et al. A causal role for ERG in neoplastic transformation of prostate epithelium. Proc Natl Acad Sci USA 2008; 105: 2105-10.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2105-2110
-
-
Klezovitch, O.1
Risk, M.2
Coleman, I.3
-
9
-
-
60149091983
-
ETS rearrangements and prostate cancer initiation
-
discussion E2-3
-
Carver BS, Tran J, Chen Z, et al. ETS rearrangements and prostate cancer initiation. Nature 2009; 457: E1; discussion E2-3.
-
(2009)
Nature
, vol.457
-
-
Carver, B.S.1
Tran, J.2
Chen, Z.3
-
10
-
-
66749188650
-
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
-
Carver BS, Tran J, Gopalan A, et al. Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nat Genet 2009; 41: 619-24.
-
(2009)
Nat Genet
, vol.41
, pp. 619-624
-
-
Carver, B.S.1
Tran, J.2
Gopalan, A.3
-
11
-
-
66749100105
-
Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
-
King JC, Xu J, Wongvipat J, et al. Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis. Nat Genet 2009; 41: 524-6.
-
(2009)
Nat Genet
, vol.41
, pp. 524-526
-
-
King, J.C.1
Xu, J.2
Wongvipat, J.3
-
12
-
-
34547642493
-
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
-
Tomlins SA, Laxman B, Dhanasekaran SM, et al. Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature 2007; 448: 595-9.
-
(2007)
Nature
, vol.448
, pp. 595-599
-
-
Tomlins, S.A.1
Laxman, B.2
Dhanasekaran, S.M.3
-
13
-
-
70350228463
-
Induction of prostatic intraepithelial neoplasia and modulation of androgen receptor by ETS variant 1/ETS-related protein 81
-
Shin S, Kim TD, Jin F, et al. Induction of prostatic intraepithelial neoplasia and modulation of androgen receptor by ETS variant 1/ETS-related protein 81. Cancer Res 2009; 69: 8102-10.
-
(2009)
Cancer Res
, vol.69
, pp. 8102-8110
-
-
Shin, S.1
Kim, T.D.2
Jin, F.3
-
14
-
-
0029745683
-
Development of seven new human prostate tumor xenograft models and their histopathological characterization
-
van Weerden WM, de Ridder CM, Verdaasdonk CL, et al. Development of seven new human prostate tumor xenograft models and their histopathological characterization. Am J Pathol 1996; 149: 1055-62.
-
(1996)
Am J Pathol
, vol.149
, pp. 1055-1062
-
-
Van Weerden, W.M.1
De Ridder, C.M.2
Verdaasdonk, C.L.3
-
15
-
-
33845329915
-
TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer
-
Hermans KG, van Marion R, van Dekken H, et al. TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer. Cancer Res 2006; 66: 10658-63.
-
(2006)
Cancer Res
, vol.66
, pp. 10658-10663
-
-
Hermans, K.G.1
Van Marion, R.2
Van Dekken, H.3
-
16
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
Tusher VG, Tibshirani R, Chu G,. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 2001; 98: 5116-21.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
17
-
-
0032441150
-
Cluster analysis and display of genome-wide expression patterns
-
Eisen MB, Spellman PT, Brown PO, et al. Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA 1998; 95: 14863-8.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14863-14868
-
-
Eisen, M.B.1
Spellman, P.T.2
Brown, P.O.3
-
18
-
-
77954255681
-
Integrative genomic profiling of human prostate cancer
-
Taylor BS, Schultz N, Hieronymus H, et al. Integrative genomic profiling of human prostate cancer. Cancer Cell 2010; 18: 1-12.
-
(2010)
Cancer Cell
, vol.18
, pp. 1-12
-
-
Taylor, B.S.1
Schultz, N.2
Hieronymus, H.3
-
19
-
-
38649092412
-
Mapping of TMPRSS2-ERG fusions in the context of multi-focal prostate cancer
-
Furusato B, Gao CL, Ravindranath L, et al. Mapping of TMPRSS2-ERG fusions in the context of multi-focal prostate cancer. Mod Pathol 2008; 21: 67-75.
-
(2008)
Mod Pathol
, vol.21
, pp. 67-75
-
-
Furusato, B.1
Gao, C.L.2
Ravindranath, L.3
-
20
-
-
50349093250
-
Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications
-
Mosquera JM, Perner S, Genega EM, et al. Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications. Clin Cancer Res 2008; 14: 3380-5.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3380-3385
-
-
Mosquera, J.M.1
Perner, S.2
Genega, E.M.3
-
21
-
-
34447342868
-
TMPRSS2-ERG fusion prostate cancer: An early molecular event associated with invasion
-
Perner S, Mosquera JM, Demichelis F, et al. TMPRSS2-ERG fusion prostate cancer: an early molecular event associated with invasion. Am J Surg Pathol 2007; 31: 882-8.
-
(2007)
Am J Surg Pathol
, vol.31
, pp. 882-888
-
-
Perner, S.1
Mosquera, J.M.2
Demichelis, F.3
-
22
-
-
50549095607
-
Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: Results from a population-based study of prostate cancer
-
Fitzgerald LM, Agalliu I, Johnson K, et al. Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: Results from a population-based study of prostate cancer. BMC Cancer 2008; 8: 230.
-
(2008)
BMC Cancer
, vol.8
, pp. 230
-
-
Fitzgerald, L.M.1
Agalliu, I.2
Johnson, K.3
-
23
-
-
60549107254
-
TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy
-
Gopalan A, Leversha MA, Satagopan JM, et al. TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy. Cancer Res 2009; 69: 1400-6.
-
(2009)
Cancer Res
, vol.69
, pp. 1400-1406
-
-
Gopalan, A.1
Leversha, M.A.2
Satagopan, J.M.3
-
24
-
-
70350231922
-
Overexpression of prostate-specific TMPRSS2(exon 0)-ERG fusion transcripts corresponds with favorable prognosis of prostate cancer
-
Hermans KG, Boormans JL, Gasi D, et al. Overexpression of prostate-specific TMPRSS2(exon 0)-ERG fusion transcripts corresponds with favorable prognosis of prostate cancer. Clin Cancer Res 2009; 15: 6398-403.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6398-6403
-
-
Hermans, K.G.1
Boormans, J.L.2
Gasi, D.3
-
25
-
-
84857781655
-
ERG immunohistochemistry is not prededictive for PSA recureence, local recurrence, or overall survival after radical prostatectomy for prostate cancer
-
Hoogland AM, Jenster G, van Weerden WM, et al. ERG immunohistochemistry is not prededictive for PSA recureence, local recurrence, or overall survival after radical prostatectomy for prostate cancer. Mod Pathol 2012; 25: 471-9.
-
(2012)
Mod Pathol
, vol.25
, pp. 471-479
-
-
Hoogland, A.M.1
Jenster, G.2
Van Weerden, W.M.3
-
26
-
-
38049123346
-
Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer
-
Attard G, Clark J, Ambroisine L, et al. Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer. Oncogene 2008; 27: 253-63.
-
(2008)
Oncogene
, vol.27
, pp. 253-263
-
-
Attard, G.1
Clark, J.2
Ambroisine, L.3
-
27
-
-
34248510706
-
TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort
-
Demichelis F, Fall K, Perner S, et al. TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort. Oncogene 2007; 26: 4596-9.
-
(2007)
Oncogene
, vol.26
, pp. 4596-4599
-
-
Demichelis, F.1
Fall, K.2
Perner, S.3
-
28
-
-
37049015104
-
Expression of the TMPRSS2:ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer
-
Nam RK, Sugar L, Yang W, et al. Expression of the TMPRSS2:ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer. Br J Cancer 2007; 97: 1690-5.
-
(2007)
Br J Cancer
, vol.97
, pp. 1690-1695
-
-
Nam, R.K.1
Sugar, L.2
Yang, W.3
-
29
-
-
20444493600
-
Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome
-
Petrovics G, Liu A, Shaheduzzaman S, et al. Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome. Oncogene 2005; 24: 3847-52.
-
(2005)
Oncogene
, vol.24
, pp. 3847-3852
-
-
Petrovics, G.1
Liu, A.2
Shaheduzzaman, S.3
-
30
-
-
50349102353
-
TMPRSS2:ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis
-
Saramaki OR, Harjula AE, Martikainen PM, et al. TMPRSS2:ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis. Clin Cancer Res 2008; 14: 3395-400.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3395-3400
-
-
Saramaki, O.R.1
Harjula, A.E.2
Martikainen, P.M.3
-
31
-
-
79957941300
-
Confirmation of the association of TMPRSS2(exon 0)-ERG expression and a favourable prognosis of primary prostate cancer
-
Boormans JL, Porkka K, Visakorpi T, et al. Confirmation of the association of TMPRSS2(exon 0)-ERG expression and a favourable prognosis of primary prostate cancer. Eur Urol 2011; 60: 183-4.
-
(2011)
Eur Urol
, vol.60
, pp. 183-184
-
-
Boormans, J.L.1
Porkka, K.2
Visakorpi, T.3
-
32
-
-
33845884027
-
Integrative molecular concept modeling of prostate cancer progression
-
Tomlins SA, Mehra R, Rhodes DR, et al. Integrative molecular concept modeling of prostate cancer progression. Nat Genet 2007; 39: 41-51.
-
(2007)
Nat Genet
, vol.39
, pp. 41-51
-
-
Tomlins, S.A.1
Mehra, R.2
Rhodes, D.R.3
-
33
-
-
51649115957
-
TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation
-
Sun C, Dobi A, Mohamed A, et al. TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation. Oncogene 2008; 27: 5348-53.
-
(2008)
Oncogene
, vol.27
, pp. 5348-5353
-
-
Sun, C.1
Dobi, A.2
Mohamed, A.3
-
34
-
-
33751260934
-
TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming
-
Iljin K, Wolf M, Edgren H, et al. TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming. Cancer Res 2006; 66: 10242-6.
-
(2006)
Cancer Res
, vol.66
, pp. 10242-10246
-
-
Iljin, K.1
Wolf, M.2
Edgren, H.3
-
35
-
-
44949204525
-
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer
-
Setlur SR, Mertz KD, Hoshida Y, et al. Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer. J Natl Cancer Inst 2008; 100: 815-25.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 815-825
-
-
Setlur, S.R.1
Mertz, K.D.2
Hoshida, Y.3
-
36
-
-
76349124866
-
Prostate cancer genes associated with TMPRSS2-ERG gene fusion and prognostic of biochemical recurrence in multiple cohorts
-
Barwick BG, Abramovitz M, Kodani M, et al. Prostate cancer genes associated with TMPRSS2-ERG gene fusion and prognostic of biochemical recurrence in multiple cohorts. Br J Cancer 2010; 102: 570-6.
-
(2010)
Br J Cancer
, vol.102
, pp. 570-576
-
-
Barwick, B.G.1
Abramovitz, M.2
Kodani, M.3
-
37
-
-
64249128160
-
Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer
-
Jhavar S, Brewer D, Edwards S, et al. Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer. BJU Int 2009; 103: 1256-69.
-
(2009)
BJU Int
, vol.103
, pp. 1256-1269
-
-
Jhavar, S.1
Brewer, D.2
Edwards, S.3
-
38
-
-
38749125174
-
Detection of TMPRSS2-ERG translocations in human prostate cancer by expression profiling using GeneChip Human Exon 1.0 ST arrays
-
Jhavar S, Reid A, Clark J, et al. Detection of TMPRSS2-ERG translocations in human prostate cancer by expression profiling using GeneChip Human Exon 1.0 ST arrays. J Mol Diagn 2008; 10: 50-7.
-
(2008)
J Mol Diagn
, vol.10
, pp. 50-57
-
-
Jhavar, S.1
Reid, A.2
Clark, J.3
-
39
-
-
82655183787
-
TMPRSS2-ERG-specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-ß signaling
-
Brase JC, Johannes M, Mannsperger H, et al. TMPRSS2-ERG-specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-ß signaling. BMC Cancer 2011; 11: 507.
-
(2011)
BMC Cancer
, vol.11
, pp. 507
-
-
Brase, J.C.1
Johannes, M.2
Mannsperger, H.3
-
40
-
-
84865619515
-
Molecular subtyping of primary prostate cancer reveals specific and shared target genes of different ETS rearrangements
-
Paulo P, Ribeiro FR, Santos J, et al. Molecular subtyping of primary prostate cancer reveals specific and shared target genes of different ETS rearrangements. Neoplasia 2012; 14: 600-11.
-
(2012)
Neoplasia
, vol.14
, pp. 600-611
-
-
Paulo, P.1
Ribeiro, F.R.2
Santos, J.3
-
41
-
-
79951838697
-
ERG oncogene modulates prostaglandin signaling in prostate cancer cells
-
Mohamed AA, Tan SH, Sun C, et al. ERG oncogene modulates prostaglandin signaling in prostate cancer cells. Cancer Biol Ther 2011; 11: 410-7.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 410-417
-
-
Mohamed, A.A.1
Tan, S.H.2
Sun, C.3
-
42
-
-
77956998042
-
Promoter hypomethylation and upregulation of trefoil factors in prostate cancer
-
Vestergaard EM, Nexo E, Torring N, et al. Promoter hypomethylation and upregulation of trefoil factors in prostate cancer. Int J Cancer 2010; 127: 1857-65.
-
(2010)
Int J Cancer
, vol.127
, pp. 1857-1865
-
-
Vestergaard, E.M.1
Nexo, E.2
Torring, N.3
-
43
-
-
78649890593
-
ERG cooperates with androgen receptor in regulating trefoil factor 3 in prostate cancer disease progression
-
Rickman DS, Chen YB, Banerjee S, et al. ERG cooperates with androgen receptor in regulating trefoil factor 3 in prostate cancer disease progression. Neoplasia 2010; 12: 1031-40.
-
(2010)
Neoplasia
, vol.12
, pp. 1031-1040
-
-
Rickman, D.S.1
Chen, Y.B.2
Banerjee, S.3
-
44
-
-
73949084329
-
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi
-
Chen C, Jin J, James DA, et al. Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Proc Natl Acad Sci USA 2009; 106: 20336-41.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 20336-20341
-
-
Chen, C.1
Jin, J.2
James, D.A.3
-
45
-
-
70349981885
-
Associations between PIWI proteins and TDRD1/MTR-1 are critical for integrated subcellular localization in murine male germ cells
-
Kojima K, Kuramochi-Miyagawa S, Chuma S, et al. Associations between PIWI proteins and TDRD1/MTR-1 are critical for integrated subcellular localization in murine male germ cells. Genes Cells 2009; 14: 1155-65.
-
(2009)
Genes Cells
, vol.14
, pp. 1155-1165
-
-
Kojima, K.1
Kuramochi-Miyagawa, S.2
Chuma, S.3
-
46
-
-
33750482567
-
Tdrd1/Mtr-1, a tudor-related gene, is essential for male germ-cell differentiation and nuage/germinal granule formation in mice
-
Chuma S, Hosokawa M, Kitamura K, et al. Tdrd1/Mtr-1, a tudor-related gene, is essential for male germ-cell differentiation and nuage/germinal granule formation in mice. Proc Natl Acad Sci USA 2006; 103: 15894-9.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 15894-15899
-
-
Chuma, S.1
Hosokawa, M.2
Kitamura, K.3
-
47
-
-
67349141725
-
Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile
-
Reuter M, Chuma S, Tanaka T, et al. Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile. Nat Struct Mol Biol 2009; 16: 639-46.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 639-646
-
-
Reuter, M.1
Chuma, S.2
Tanaka, T.3
-
48
-
-
54749140079
-
Truncated ETV1, fused to novel tissue-specific genes, and full-length ETV1 in prostate cancer
-
Hermans KG, van der Korput HA, van Marion R, et al. Truncated ETV1, fused to novel tissue-specific genes, and full-length ETV1 in prostate cancer. Cancer Res 2008; 68: 7541-9.
-
(2008)
Cancer Res
, vol.68
, pp. 7541-7549
-
-
Hermans, K.G.1
Van Der Korput, H.A.2
Van Marion, R.3
-
49
-
-
77954954652
-
Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo
-
Wei GH, Badis G, Berger MF, et al. Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo. EMBO J 2010; 29: 2147-60.
-
(2010)
EMBO J
, vol.29
, pp. 2147-2160
-
-
Wei, G.H.1
Badis, G.2
Berger, M.F.3
-
50
-
-
34547411003
-
ETV1 is a novel androgen receptor-regulated gene that mediates prostate cancer cell invasion
-
Cai C, Hsieh CL, Omwancha J, et al. ETV1 is a novel androgen receptor-regulated gene that mediates prostate cancer cell invasion. Mol Endocrinol 2007; 21: 1835-46.
-
(2007)
Mol Endocrinol
, vol.21
, pp. 1835-1846
-
-
Cai, C.1
Hsieh, C.L.2
Omwancha, J.3
|