메뉴 건너뛰기




Volumn 88, Issue 4, 2013, Pages 728-739

The nuclear mRNA export receptor Mex67-Mtr2 of Trypanosoma brucei contains a unique and essential zinc finger motif

Author keywords

[No Author keywords available]

Indexed keywords

HETERODIMER; KARYOPHERIN; MESSENGER RNA; PEPTIDES AND PROTEINS; PROTEIN IMP1; PROTEIN MEX67; PROTEIN MTR2; UNCLASSIFIED DRUG;

EID: 84877792571     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.12217     Document Type: Article
Times cited : (35)

References (43)
  • 1
    • 70049084728 scopus 로고    scopus 로고
    • Trypanosoma brucei PUF9 regulates mRNAs for proteins involved in replicative processes over the cell cycle
    • and () . : .
    • Archer, S.K., Luu, V.D., de Queiroz, R.A., Brems, S., and Clayton, C. (2009) Trypanosoma brucei PUF9 regulates mRNAs for proteins involved in replicative processes over the cell cycle. PLoS Pathog 5: e1000565.
    • (2009) PLoS Pathog , vol.5
    • Archer, S.K.1    Luu, V.D.2    de Queiroz, R.A.3    Brems, S.4    Clayton, C.5
  • 2
    • 67349110426 scopus 로고    scopus 로고
    • Identification of core components of the exon junction complex in trypanosomes
    • Bercovich, N., Levin, M.J., Clayton, C., and Vazquez, M. (2009) Identification of core components of the exon junction complex in trypanosomes. Mol Biochem Parasitol 166: 190-193.
    • (2009) Mol Biochem Parasitol , vol.166 , pp. 190-193
    • Bercovich, N.1    Levin, M.J.2    Clayton, C.3    Vazquez, M.4
  • 3
    • 0018601361 scopus 로고
    • Schonenberger Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Short communication
    • Brun, R., and Schonenberger (1979) Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Short communication. Acta Trop 36: 289-292.
    • (1979) Acta Trop , vol.36 , pp. 289-292
    • Brun, R.1
  • 5
    • 68949187846 scopus 로고    scopus 로고
    • mRNA nuclear export at a glance
    • Carmody, S.R., and Wente, S.R. (2009) mRNA nuclear export at a glance. J Cell Sci 122: 1933-1937.
    • (2009) J Cell Sci , vol.122 , pp. 1933-1937
    • Carmody, S.R.1    Wente, S.R.2
  • 6
    • 34447572786 scopus 로고    scopus 로고
    • Recruitment of mRNAs to cytoplasmic ribonucleoprotein granules in trypanosomes
    • Cassola, A., De Gaudenzi, J.G., and Frasch, A.C. (2007) Recruitment of mRNAs to cytoplasmic ribonucleoprotein granules in trypanosomes. Mol Microbiol 65: 655-670.
    • (2007) Mol Microbiol , vol.65 , pp. 655-670
    • Cassola, A.1    De Gaudenzi, J.G.2    Frasch, A.C.3
  • 7
    • 0034329461 scopus 로고    scopus 로고
    • A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae
    • Chavez, S., Beilharz, T., Rondon, A.G., Erdjument-Bromage, H., Tempst, P., Svejstrup, J.Q., etal. (2000) A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae. EMBO J 19: 5824-5834.
    • (2000) EMBO J , vol.19 , pp. 5824-5834
    • Chavez, S.1    Beilharz, T.2    Rondon, A.G.3    Erdjument-Bromage, H.4    Tempst, P.5    Svejstrup, J.Q.6
  • 8
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 9
    • 84867678330 scopus 로고    scopus 로고
    • The essential polysome-associated RNA-binding protein RBP42 targets mRNAs involved in Trypanosoma brucei energy metabolism
    • Das, A., Morales, R., Banday, M., Garcia, S., Hao, L., Cross, G.A., etal. (2012) The essential polysome-associated RNA-binding protein RBP42 targets mRNAs involved in Trypanosoma brucei energy metabolism. RNA 18: 1968-1983.
    • (2012) RNA , vol.18 , pp. 1968-1983
    • Das, A.1    Morales, R.2    Banday, M.3    Garcia, S.4    Hao, L.5    Cross, G.A.6
  • 10
    • 71049191352 scopus 로고    scopus 로고
    • Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor
    • DeGrasse, J.A., DuBois, K.N., Devos, D., Siegel, T.N., Sali, A., Field, M.C., etal. (2009) Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor. Mol Cell Proteomics 8: 2119-2130.
    • (2009) Mol Cell Proteomics , vol.8 , pp. 2119-2130
    • DeGrasse, J.A.1    DuBois, K.N.2    Devos, D.3    Siegel, T.N.4    Sali, A.5    Field, M.C.6
  • 11
    • 49249093497 scopus 로고    scopus 로고
    • The RNA-binding protein TbDRBD3 regulates the stability of a specific subset of mRNAs in trypanosomes
    • Estevez, A.M. (2008) The RNA-binding protein TbDRBD3 regulates the stability of a specific subset of mRNAs in trypanosomes. Nucleic Acids Res 36: 4573-4586.
    • (2008) Nucleic Acids Res , vol.36 , pp. 4573-4586
    • Estevez, A.M.1
  • 12
    • 79953776282 scopus 로고    scopus 로고
    • Posttranscriptional control and the role of RNA-binding proteins in gene regulation in trypanosomatid protozoan parasites
    • Fernández-Moya, S.M., and Estévez, A.M. (2010) Posttranscriptional control and the role of RNA-binding proteins in gene regulation in trypanosomatid protozoan parasites. Wiley Interdiscip Rev RNA 1: 34-46.
    • (2010) Wiley Interdiscip Rev RNA , vol.1 , pp. 34-46
    • Fernández-Moya, S.M.1    Estévez, A.M.2
  • 13
    • 1842417078 scopus 로고    scopus 로고
    • Elements in the 3′ untranslated region of procyclin mRNA regulate expression in insect forms of Trypanosoma brucei by modulating RNA stability and translation
    • Furger, A., Schurch, N., Kurath, U., and Roditi, I. (1997) Elements in the 3′ untranslated region of procyclin mRNA regulate expression in insect forms of Trypanosoma brucei by modulating RNA stability and translation. Mol Cell Biol 17: 4372-4380.
    • (1997) Mol Cell Biol , vol.17 , pp. 4372-4380
    • Furger, A.1    Schurch, N.2    Kurath, U.3    Roditi, I.4
  • 14
    • 0037040895 scopus 로고    scopus 로고
    • Nab2p is required for poly(A) RNA export in Saccharomyces cerevisiae and is regulated by arginine methylation via Hmt1p
    • Green, D.M., Marfatia, K.A., Crafton, E.B., Zhang, X., Cheng, X., and Corbett, A.H. (2002) Nab2p is required for poly(A) RNA export in Saccharomyces cerevisiae and is regulated by arginine methylation via Hmt1p. J Biol Chem 277: 7752-7760.
    • (2002) J Biol Chem , vol.277 , pp. 7752-7760
    • Green, D.M.1    Marfatia, K.A.2    Crafton, E.B.3    Zhang, X.4    Cheng, X.5    Corbett, A.H.6
  • 15
    • 77956841596 scopus 로고    scopus 로고
    • The pre-mRNA splicing machinery of trypanosomes: complex or simplified?
    • Gunzl, A. (2010) The pre-mRNA splicing machinery of trypanosomes: complex or simplified? Eukaryot Cell 9: 1159-1170.
    • (2010) Eukaryot Cell , vol.9 , pp. 1159-1170
    • Gunzl, A.1
  • 17
    • 33750616165 scopus 로고    scopus 로고
    • The procyclin-associated genes of Trypanosoma brucei are not essential for cyclical transmission by tsetse
    • Haenni, S., Renggli, C.K., Fragoso, C.M., Oberle, M., and Roditi, I. (2006) The procyclin-associated genes of Trypanosoma brucei are not essential for cyclical transmission by tsetse. Mol Biochem Parasitol 150: 144-156.
    • (2006) Mol Biochem Parasitol , vol.150 , pp. 144-156
    • Haenni, S.1    Renggli, C.K.2    Fragoso, C.M.3    Oberle, M.4    Roditi, I.5
  • 18
    • 0028053101 scopus 로고
    • A conserved stem-loop structure in the 3′ untranslated region of procyclin mRNAs regulates expression in Trypanosoma brucei
    • Hehl, A., Vassella, E., Braun, R., and Roditi, I. (1994) A conserved stem-loop structure in the 3′ untranslated region of procyclin mRNAs regulates expression in Trypanosoma brucei. Proc Natl Acad Sci USA 91: 370-374.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 370-374
    • Hehl, A.1    Vassella, E.2    Braun, R.3    Roditi, I.4
  • 19
    • 44449169243 scopus 로고    scopus 로고
    • Regulation of mRNP dynamics along the export pathway
    • Iglesias, N., and Stutz, F. (2008) Regulation of mRNP dynamics along the export pathway. FEBS Lett 582: 1987-1996.
    • (2008) FEBS Lett , vol.582 , pp. 1987-1996
    • Iglesias, N.1    Stutz, F.2
  • 20
    • 34648816826 scopus 로고    scopus 로고
    • Exporting RNA from the nucleus to the cytoplasm
    • Kohler, A., and Hurt, E. (2007) Exporting RNA from the nucleus to the cytoplasm. Nat Rev Mol Cell Biol 8: 761-773.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 761-773
    • Kohler, A.1    Hurt, E.2
  • 21
    • 78149292214 scopus 로고    scopus 로고
    • The transcriptome of the human pathogen Trypanosoma brucei at single-nucleotide resolution
    • and () . : .
    • Kolev, N.G., Franklin, J.B., Carmi, S., Shi, H., Michaeli, S., and Tschudi, C. (2010) The transcriptome of the human pathogen Trypanosoma brucei at single-nucleotide resolution. PLoS Pathog 6: e1001090.
    • (2010) PLoS Pathog , vol.6
    • Kolev, N.G.1    Franklin, J.B.2    Carmi, S.3    Shi, H.4    Michaeli, S.5    Tschudi, C.6
  • 22
    • 78650533544 scopus 로고    scopus 로고
    • Trans-acting proteins regulating mRNA maturation, stability and translation in trypanosomatids
    • Kramer, S., and Carrington, M. (2011) Trans-acting proteins regulating mRNA maturation, stability and translation in trypanosomatids. Trends Parasitol 27: 23-30.
    • (2011) Trends Parasitol , vol.27 , pp. 23-30
    • Kramer, S.1    Carrington, M.2
  • 23
    • 77951827772 scopus 로고    scopus 로고
    • Genome-wide in silico screen for CCCH-type zinc finger proteins of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major
    • and () . : .
    • Kramer, S., Kimblin, N.C., and Carrington, M. (2010) Genome-wide in silico screen for CCCH-type zinc finger proteins of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major. BMC Genomics 11: 283.
    • (2010) BMC Genomics , vol.11 , pp. 283
    • Kramer, S.1    Kimblin, N.C.2    Carrington, M.3
  • 24
    • 0034672093 scopus 로고    scopus 로고
    • The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions
    • Le Hir, H., Izaurralde, E., Maquat, L.E., and Moore, M.J. (2000) The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions. EMBO J 19: 6860-6869.
    • (2000) EMBO J , vol.19 , pp. 6860-6869
    • Le Hir, H.1    Izaurralde, E.2    Maquat, L.E.3    Moore, M.J.4
  • 25
    • 0036829415 scopus 로고    scopus 로고
    • Intron status and 3′-end formation control cotranscriptional export of mRNA
    • Lei, E.P., and Silver, P.A. (2002) Intron status and 3′-end formation control cotranscriptional export of mRNA. Genes Dev 16: 2761-2766.
    • (2002) Genes Dev , vol.16 , pp. 2761-2766
    • Lei, E.P.1    Silver, P.A.2
  • 27
    • 79960647138 scopus 로고    scopus 로고
    • Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery
    • Mani, J., Guttinger, A., Schimanski, B., Heller, M., Acosta-Serrano, A., Pescher, P., etal. (2011) Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery. PLoS ONE 6: e22463.
    • (2011) PLoS ONE , vol.6
    • Mani, J.1    Guttinger, A.2    Schimanski, B.3    Heller, M.4    Acosta-Serrano, A.5    Pescher, P.6
  • 28
    • 77958123318 scopus 로고    scopus 로고
    • Spliced leader trapping reveals widespread alternative splicing patterns in the highly dynamic transcriptome of Trypanosoma brucei
    • Nilsson, D., Gunasekera, K., Mani, J., Osteras, M., Farinelli, L., Baerlocher, L., etal. (2010) Spliced leader trapping reveals widespread alternative splicing patterns in the highly dynamic transcriptome of Trypanosoma brucei. PLoS Pathog 6: e1001037.
    • (2010) PLoS Pathog , vol.6
    • Nilsson, D.1    Gunasekera, K.2    Mani, J.3    Osteras, M.4    Farinelli, L.5    Baerlocher, L.6
  • 29
    • 0029737693 scopus 로고    scopus 로고
    • Regulation of mRNA export in response to stress in Saccharomyces cerevisiae
    • Saavedra, C., Tung, K.S., Amberg, D.C., Hopper, A.K., and Cole, C.N. (1996) Regulation of mRNA export in response to stress in Saccharomyces cerevisiae. Genes Dev 10: 1608-1620.
    • (1996) Genes Dev , vol.10 , pp. 1608-1620
    • Saavedra, C.1    Tung, K.S.2    Amberg, D.C.3    Hopper, A.K.4    Cole, C.N.5
  • 30
    • 9844219734 scopus 로고    scopus 로고
    • Yeast heat shock mRNAs are exported through a distinct pathway defined by Rip1p
    • Saavedra, C.A., Hammell, C.M., Heath, C.V., and Cole, C.N. (1997) Yeast heat shock mRNAs are exported through a distinct pathway defined by Rip1p. Genes Dev 11: 2845-2856.
    • (1997) Genes Dev , vol.11 , pp. 2845-2856
    • Saavedra, C.A.1    Hammell, C.M.2    Heath, C.V.3    Cole, C.N.4
  • 31
    • 27744552907 scopus 로고    scopus 로고
    • Highly efficient tandem affinity purification of trypanosome protein complexes based on a novel epitope combination
    • Schimanski, B., Nguyen, T.N., and Gunzl, A. (2005) Highly efficient tandem affinity purification of trypanosome protein complexes based on a novel epitope combination. Eukaryot Cell 4: 1942-1950.
    • (2005) Eukaryot Cell , vol.4 , pp. 1942-1950
    • Schimanski, B.1    Nguyen, T.N.2    Gunzl, A.3
  • 33
    • 79958080545 scopus 로고    scopus 로고
    • An essential nuclear protein in trypanosomes is a component of mRNA transcription/export pathway
    • Serpeloni, M., Moraes, C.B., Muniz, J.R., Motta, M.C., Ramos, A.S., Kessler, R.L., etal. (2011a) An essential nuclear protein in trypanosomes is a component of mRNA transcription/export pathway. PLoS ONE 6: e20730.
    • (2011) PLoS ONE , vol.6
    • Serpeloni, M.1    Moraes, C.B.2    Muniz, J.R.3    Motta, M.C.4    Ramos, A.S.5    Kessler, R.L.6
  • 34
    • 78651090509 scopus 로고    scopus 로고
    • Comparative genomics of proteins involved in RNA nucleocytoplasmic export
    • and () . : .
    • Serpeloni, M., Vidal, N.M., Goldenberg, S., Avila, A.R., and Hoffmann, F.G. (2011b) Comparative genomics of proteins involved in RNA nucleocytoplasmic export. BMC Evol Biol 11: 7.
    • (2011) BMC Evol Biol , vol.11 , pp. 7
    • Serpeloni, M.1    Vidal, N.M.2    Goldenberg, S.3    Avila, A.R.4    Hoffmann, F.G.5
  • 35
    • 0037195151 scopus 로고    scopus 로고
    • Karyopherin beta 2B participates in mRNA export from the nucleus
    • Shamsher, M.K., Ploski, J., and Radu, A. (2002) Karyopherin beta 2B participates in mRNA export from the nucleus. Proc Natl Acad Sci USA 99: 14195-14199.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14195-14199
    • Shamsher, M.K.1    Ploski, J.2    Radu, A.3
  • 36
    • 80052924614 scopus 로고    scopus 로고
    • Gene expression in Trypanosoma brucei: lessons from high-throughput RNA sequencing
    • Siegel, T.N., Gunasekera, K., Cross, G.A., and Ochsenreiter, T. (2011) Gene expression in Trypanosoma brucei: lessons from high-throughput RNA sequencing. Trends Parasitol 27: 434-441.
    • (2011) Trends Parasitol , vol.27 , pp. 434-441
    • Siegel, T.N.1    Gunasekera, K.2    Cross, G.A.3    Ochsenreiter, T.4
  • 37
    • 62549158711 scopus 로고    scopus 로고
    • Multiple roles for polypyrimidine tract binding (PTB) proteins in trypanosome RNA metabolism
    • Stern, M.Z., Gupta, S.K., Salmon-Divon, M., Haham, T., Barda, O., Levi, S., etal. (2009) Multiple roles for polypyrimidine tract binding (PTB) proteins in trypanosome RNA metabolism. RNA 15: 648-665.
    • (2009) RNA , vol.15 , pp. 648-665
    • Stern, M.Z.1    Gupta, S.K.2    Salmon-Divon, M.3    Haham, T.4    Barda, O.5    Levi, S.6
  • 38
    • 78049296915 scopus 로고    scopus 로고
    • Nuclear export of mRNA
    • Stewart, M. (2010) Nuclear export of mRNA. Trends Biochem Sci 35: 609-617.
    • (2010) Trends Biochem Sci , vol.35 , pp. 609-617
    • Stewart, M.1
  • 39
    • 0141469976 scopus 로고    scopus 로고
    • Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export
    • Strasser, K., and Hurt, E. (2000) Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export. EMBO J 19: 410-420.
    • (2000) EMBO J , vol.19 , pp. 410-420
    • Strasser, K.1    Hurt, E.2
  • 41
    • 0033625090 scopus 로고    scopus 로고
    • REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export
    • Stutz, F., Bachi, A., Doerks, T., Braun, I.C., Seraphin, B., Wilm, M., etal. (2000) REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export. RNA 6: 638-650.
    • (2000) RNA , vol.6 , pp. 638-650
    • Stutz, F.1    Bachi, A.2    Doerks, T.3    Braun, I.C.4    Seraphin, B.5    Wilm, M.6
  • 42
    • 61449182673 scopus 로고    scopus 로고
    • Differential trypanosome surface coat regulation by a CCCH protein that co-associates with procyclin mRNA cis-elements
    • and () . : .
    • Walrad, P., Paterou, A., Acosta-Serrano, A., and Matthews, K.R. (2009) Differential trypanosome surface coat regulation by a CCCH protein that co-associates with procyclin mRNA cis-elements. PLoS Pathog 5: e1000317.
    • (2009) PLoS Pathog , vol.5
    • Walrad, P.1    Paterou, A.2    Acosta-Serrano, A.3    Matthews, K.R.4
  • 43
    • 0033525524 scopus 로고    scopus 로고
    • A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei
    • Wirtz, E., Leal, S., Ochatt, C., and Cross, G.A. (1999) A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei. Mol Biochem Parasitol 99: 89-101.
    • (1999) Mol Biochem Parasitol , vol.99 , pp. 89-101
    • Wirtz, E.1    Leal, S.2    Ochatt, C.3    Cross, G.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.