Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK

Nature Communications

Volumn 4, Issue , 2013, Pages

  MacE, Peter D ^a   Wallez, Yann ^a   Egger, Michael F ^a   Dobaczewska, Małgorzata K ^a   Robinson, Howard ^b   Pasquale, Elena B ^a,c   Riedl, Stefan J ^a  

^a BURNHAM INSTITUTE   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN PEA 15; SCAFFOLD PROTEIN; THREONINE; TYROSINE; UNCLASSIFIED DRUG;

ENZYME ACTIVITY; INHIBITOR; MIGRATION; PHYSIOLOGICAL RESPONSE; SIGNALING;

ARTICLE; BINDING SITE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; MOLECULAR DOCKING; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ENZYME ACTIVATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, MOLECULAR; PHOSPHOPROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84877784680     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms2687     Document Type: Article

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