Phosphorylation is the switch that turns PEA-15 from tumor suppressor to tumor promoter

Small GTPases

Volumn 3, Issue 3, 2012, Pages 173-177

  Sulzmaier, Florian J ^a,b   Opoku Ansah, John ^a,b   Ramos, Joe W ^a,b  

^a UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^b UNIVERSITY OF HAWAII   (United States)

Author keywords

Cell transformation; ERK cascade; PEA 15; Phosphorylation; PLD; Ras

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; EPIDERMAL GROWTH FACTOR; PHOSPHOPROTEIN; PHOSPHOPROTEIN ENRICHED IN ASTROCYTES 15; PROTEIN KINASE C; RAS PROTEIN; SELUMETINIB; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CANCER GROWTH; CARBOXY TERMINAL SEQUENCE; CARCINOGENESIS; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL SURVIVAL; EPITHELIUM CELL; FIBROBLAST; GENE MUTATION; HUMAN; NONHUMAN; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMOCYTE; TUMOR SUPPRESSOR GENE; UPREGULATION;

EID: 84863808329     PISSN: 21541248     EISSN: 21541256     Source Type: Journal    
DOI: 10.4161/sgtp.20021     Document Type: Article

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