Lower ADD1 Gene Promoter DNA Methylation Increases the Risk of Essential Hypertension

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Zhang, Li Na ^a   Liu, Pan Pan ^a   Wang, Lingyan ^b   Yuan, Fang ^a   Xu, Leiting ^a   Xin, Yanfei ^c   Fei, Li Juan ^a   Zhong, Qi Long ^a   Huang, Yi ^a   Xu, Limin ^a   Hao, Ling Mei ^d   Qiu, Xu Jun ^d   Le, Yanping ^a   Ye, Meng ^a   Duan, Shiwei ^a  

^a NINGBO UNIVERSITY   (China)

^b NINGBO NO 2 HOSPITAL   (China)

^c INSTITUTE OF MATERIA MEDICA   (China)

^d Seventh Hospital of Ningbo   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA ADDUCIN; ALPHA ADDUCIN 1; ASPARTATE AMINOTRANSFERASE; CYTOSINE; DNA; THYMINE; UNCLASSIFIED DRUG; URIC ACID;

ADD1 GENE; ADULT; AGE; AMINO ACID SUBSTITUTION; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CPG ISLAND; DISEASE ASSOCIATION; DNA METHYLATION; ESSENTIAL HYPERTENSION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; POSTMENOPAUSE; PREDICTION; PREMENOPAUSE; PROMOTER REGION; PYROSEQUENCING; RISK ASSESSMENT; SEX DIFFERENCE;

CPG ISLANDS; DNA METHYLATION; FEMALE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; PROMOTER REGIONS, GENETIC; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 84877770249     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063455     Document Type: Article

References (70)

1. He J, Bazzano LA, Chen CS, Chen J, Rao DC, et al. (2007) GenSalt: rationale, design, methods and baseline characteristics of study participants. J Hum Hypertens 21: 639-646.
2. Svetkey LP, Harris EL, Martin E, Vollmer WM, Meltesen GT, et al. (2011) Modulation of the BP response to diet by genes in the renin-angiotensin system and the adrenergic nervous system. Am J Hypertens 24: 209-217.
3. Kurtz TW, Spence MA, (1993) Genetics of essential hypertension. Am J Med 94: 77-84.
4. Binder A, (2007) A review of the genetics of essential hypertension. Curr Opin Cardiol 22: 176-184.
5. Whelton PK, He J, Appel LJ, Cutler JA, Havas S, et al. (2002) Primary prevention of hypertension: clinical and public health advisory from The National High Blood Pressure Education Program. JAMA 288: 1882-1888.
6. Zhang X, Giovannucci EL, Wu K, Smith-Warner SA, Fuchs CS, et al. (2012) Magnesium intake, plasma C-peptide, and colorectal cancer incidence in US women: a 28-year follow-up study. Br J Cancer 106: 1335-1341.
7. Tohidi M, Hatami M, Hadaegh F, Azizi F, (2012) Triglycerides and triglycerides to high-density lipoprotein cholesterol ratio are strong predictors of incident hypertension in Middle Eastern women. J Hum Hypertens 26: 525-532.
8. Gilbert JS, Nijland MJ, (2008) Sex differences in the developmental origins of hypertension and cardiorenal disease. Am J Physiol Regul Integr Comp Physiol 295: R1941-1952.
9. Fisher ND, Ferri C, Bellini C, Santucci A, Gleason R, et al. (1997) Age, gender, and non-modulation. A sexual dimorphism in essential hypertension. Hypertension 29: 980-985.
10. Dzudie A, Kengne AP, Muna WF, Ba H, Menanga A, et al. (2012) Prevalence, awareness, treatment and control of hypertension in a self-selected sub-Saharan African urban population: a cross-sectional study. BMJ Open 2.
11. Coatmellec-Taglioni G, Dausse JP, Giudicelli Y, Ribiere C, (2002) Gender difference in diet-induced obesity hypertension: implication of renal alpha2-adrenergic receptors. Am J Hypertens 15: 143-149.
12. Silva-Antonialli MM, Tostes RC, Fernandes L, Fior-Chadi DR, Akamine EH, et al. (2004) A lower ratio of AT1/AT2 receptors of angiotensin II is found in female than in male spontaneously hypertensive rats. Cardiovasc Res 62: 587-593.
13. Danser AH, Derkx FH, Schalekamp MA, Hense HW, Riegger GA, et al. (1998) Determinants of interindividual variation of renin and prorenin concentrations: evidence for a sexual dimorphism of (pro)renin levels in humans. J Hypertens 16: 853-862.
14. Bachmann J, Feldmer M, Ganten U, Stock G, Ganten D, (1991) Sexual dimorphism of blood pressure: possible role of the renin-angiotensin system. J Steroid Biochem Mol Biol 40: 511-515.
15. Rands VF, Seth DM, Kobori H, Prieto MC, (2012) Sexual dimorphism in urinary angiotensinogen excretion during chronic angiotensin II-salt hypertension. Gend Med 9: 207-218.
16. Rinn JL, Snyder M, (2005) Sexual dimorphism in mammalian gene expression. Trends Genet 21: 298-305.
17. Matsuoka Y, Li X, Bennett V, (2000) Adducin: structure, function and regulation. Cell Mol Life Sci 57: 884-895.
18. Tripodi G, Valtorta F, Torielli L, Chieregatti E, Salardi S, et al. (1996) Hypertension-associated point mutations in the adducin alpha and beta subunits affect actin cytoskeleton and ion transport. J Clin Invest 97: 2815-2822.
19. Casari G, Barlassina C, Cusi D, Zagato L, Muirhead R, et al. (1995) Association of the alpha-adducin locus with essential hypertension. Hypertension 25: 320-326.
20. Manunta P, Cusi D, Barlassina C, Righetti M, Lanzani C, et al. (1998) Alpha-adducin polymorphisms and renal sodium handling in essential hypertensive patients. Kidney Int 53: 1471-1478.
21. Iwai N, Tamaki S, Nakamura Y, Kinoshita M, (1997) Polymorphism of alpha-adducin and hypertension. Lancet 350: 369.
22. Kamitani A, Wong ZY, Fraser R, Davies DL, Connor JM, et al. (1998) Human alpha-adducin gene, blood pressure, and sodium metabolism. Hypertension 32: 138-143.
23. Busch CP, Harris SB, Hanley AJ, Zinman B, Hegele RA, (1999) The ADD1 G460W polymorphism is not associated with variation in blood pressure in Canadian Oji-Cree. J Hum Genet 44: 225-229.
24. Ramu P, Umamaheswaran G, Shewade DG, Swaminathan RP, Balachander J, et al. (2010) Gly460Trp polymorphism of the ADD1 gene and essential hypertension in an Indian population: A meta-analysis on hypertension risk. Indian J Hum Genet 16: 8-15.
25. Liu K, Liu J, Huang Y, Liu Y, Lou Y, et al. (2010) Alpha-adducin Gly460Trp polymorphism and hypertension risk: a meta-analysis of 22 studies including 14303 cases and 15961 controls. PLoS One 5.
26. Niu W, Qi Y, (2011) Association of alpha-adducin and G-protein beta3 genetic polymorphisms with hypertension: a meta-analysis of Chinese populations. PLoS One 6: e17052.
27. Liu K, Liu Y, Liu J, Wang Z, Lou Y, et al. (2011) alpha-adducin Gly460Trp polymorphism and essential hypertension risk in Chinese: a meta-analysis. Hypertens Res 34: 389-399.
28. Li YY, (2012) alpha-Adducin Gly460Trp gene mutation and essential hypertension in a Chinese population: a meta-analysis including 10,960 subjects. PLoS One 7: e30214.
29. Wang JG, Staessen JA, Barlassina C, Fagard R, Kuznetsova T, et al. (2002) Association between hypertension and variation in the alpha- and beta-adducin genes in a white population. Kidney Int 62: 2152-2159.
30. Razin A, Webb C, Szyf M, Yisraeli J, Rosenthal A, et al. (1984) Variations in DNA methylation during mouse cell differentiation in vivo and in vitro. Proc Natl Acad Sci U S A 81: 2275-2279.
31. Morita S, Takahashi RU, Yamashita R, Toyoda A, Horii T, et al. (2012) Genome-Wide Analysis of DNA Methylation and Expression of MicroRNAs in Breast Cancer Cells. Int J Mol Sci 13: 8259-8272.
32. Grutzmann R, Molnar B, Pilarsky C, Habermann JK, Schlag PM, et al. (2008) Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay. PLoS One 3: e3759.
33. DeVos T, Tetzner R, Model F, Weiss G, Schuster M, et al. (2009) Circulating methylated SEPT9 DNA in plasma is a biomarker for colorectal cancer. Clin Chem 55: 1337-1346.
34. Muller HM, Fiegl H, Widschwendter A, Widschwendter M, (2004) Prognostic DNA methylation marker in serum of cancer patients. Ann N Y Acad Sci 1022: 44-49.
35. Muller HM, Widschwendter A, Fiegl H, Ivarsson L, Goebel G, et al. (2003) DNA methylation in serum of breast cancer patients: an independent prognostic marker. Cancer Res 63: 7641-7645.
36. Guay SP, Brisson D, Munger J, Lamarche B, Gaudet D, et al. (2012) ABCA1 gene promoter DNA methylation is associated with HDL particle profile and coronary artery disease in familial hypercholesterolemia. Epigenetics 7: 464-472.
37. Xu H, Wang B, Su D, Yu Q, Li Q, et al. (2012) The DNA methylation profile of PLA2G4C gene promoter in schizophrenia. Psychiatry Res.
38. Kinoshita M, Numata S, Tajima A, Shimodera S, Ono S, et al. (2012) DNA Methylation Signatures of Peripheral Leukocytes in Schizophrenia. Neuromolecular Med.
39. Smolarek I, Wyszko E, Barciszewska AM, Nowak S, Gawronska I, et al. (2010) Global DNA methylation changes in blood of patients with essential hypertension. Med Sci Monit 16: CR149-155.
40. Kulkarni A, Chavan-Gautam P, Mehendale S, Yadav H, Joshi S, (2011) Global DNA methylation patterns in placenta and its association with maternal hypertension in pre-eclampsia. DNA Cell Biol 30: 79-84.
41. Friso S, Pizzolo F, Choi SW, Guarini P, Castagna A, et al. (2008) Epigenetic control of 11 beta-hydroxysteroid dehydrogenase 2 gene promoter is related to human hypertension. Atherosclerosis 199: 323-327.
42. Jiang Q, Yuan H, Xing X, Liu J, Huang Z, et al. (2011) Methylation of adrenergic beta1 receptor is a potential epigenetic mechanism controlling antihypertensive response to metoprolol. Indian J Biochem Biophys 48: 301-307.
43. European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 21: 1011-1053.
44. Perloff D, Grim C, Flack J, Frohlich ED, Hill M, et al. (1993) Human blood pressure determination by sphygmomanometry. Circulation 88: 2460-2470.
45. Dupont WD, Plummer WD Jr, (1990) Power and sample size calculations. A review and computer program. Control Clin Trials 11: 116-128.
46. Ferrandi M, Salardi S, Tripodi G, Barassi P, Rivera R, et al. (1999) Evidence for an interaction between adducin and Na(+)-K(+)-ATPase: relation to genetic hypertension. Am J Physiol 277: H1338-1349.
47. Bianchi G, Tripodi G, Casari G, Salardi S, Barber BR, et al. (1994) Two point mutations within the adducin genes are involved in blood pressure variation. Proc Natl Acad Sci U S A 91: 3999-4003.
48. Ferrandi M, Tripodi G, Salardi S, Florio M, Modica R, et al. (1996) Renal Na,K-ATPase in genetic hypertension. Hypertension 28: 1018-1025.
49. Deng AY, Menard A, Xiao C, Roy J, (2008) Sexual dimorphism on hypertension of quantitative trait loci entrapped in Dahl congenic rats. Clin Exp Hypertens 30: 511-519.
50. Yagil C, Sapojnikov M, Kreutz R, Katni G, Lindpaintner K, et al. (1998) Salt susceptibility maps to chromosomes 1 and 17 with sex specificity in the Sabra rat model of hypertension. Hypertension 31: 119-124.
51. Seda O, Tremblay J, Gaudet D, Brunelle PL, Gurau A, et al. (2008) Systematic, genome-wide, sex-specific linkage of cardiovascular traits in French Canadians. Hypertension 51: 1156-1162.
52. Shimodaira M, Nakayama T, Sato N, Saito K, Morita A, et al. (2008) Association study of aromatase gene (CYP19A1) in essential hypertension. Int J Med Sci 5: 29-35.
53. Wang ZG, Niu QL, Gu W, Liu K, Lou YQ, et al. (2011) [Association of C602A and T1559C polymorphisms of E-selectin gene and essential hypertension]. Zhonghua Yi Xue Za Zhi 91: 1238-1241.
54. Chen A, Chen X, Shi R, Guo Y, Chen L, et al. (2009) [Association of genetic polymorphism in phenylethanolamine-N-methyl transferase with essential hypertension in Changsha Han people]. Zhong Nan Da Xue Xue Bao Yi Xue Ban 34: 1120-1125.
55. Wang Z, Nakayama T, Sato N, Izumi Y, Kasamaki Y, et al. (2010) The purinergic receptor P2Y, G-protein coupled, 2 (P2RY2) gene associated with essential hypertension in Japanese men. J Hum Hypertens 24: 327-335.
56. Sebag IA, Gillis MA, Calderone A, Kasneci A, Meilleur M, et al. (2011) Sex hormone control of left ventricular structure/function: mechanistic insights using echocardiography, expression, and DNA methylation analyses in adult mice. Am J Physiol Heart Circ Physiol 301: H1706-1715.
57. Raiche J, Rodriguez-Juarez R, Pogribny I, Kovalchuk O, (2004) Sex- and tissue-specific expression of maintenance and de novo DNA methyltransferases upon low dose X-irradiation in mice. Biochem Biophys Res Commun 325: 39-47.
58. Koturbash I, Kutanzi K, Hendrickson K, Rodriguez-Juarez R, Kogosov D, et al. (2008) Radiation-induced bystander effects in vivo are sex specific. Mutat Res 642: 28-36.
59. Zhang X, Ho SM, (2011) Epigenetics meets endocrinology. J Mol Endocrinol 46: R11-32.
60. Reynolds E, (2006) Vitamin B12, folic acid, and the nervous system. Lancet Neurol 5: 949-960.
61. Dong E, Nelson M, Grayson DR, Costa E, Guidotti A, (2008) Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation. Proc Natl Acad Sci U S A 105: 13614-13619.
62. Melas PA, Rogdaki M, Osby U, Schalling M, Lavebratt C, et al. (2012) Epigenetic aberrations in leukocytes of patients with schizophrenia: association of global DNA methylation with antipsychotic drug treatment and disease onset. FASEB J 26: 2712-2718.
63. Chen DL, Zhang CJ, Fu YH, Mo YJ, Chen FR (2010) [Correlation of angiotensin-converting enzyme 2 gene polymorphisms to essential hypertension and ischemic stroke]. Nan Fang Yi Ke Da Xue Xue Bao 30: 1890-1892, 1895.
64. Mo YJ, Huang WH, Chen DL, Chen FR, (2010) [Relationship of angiotensin-converting enzyme 2 gene polymorphism with the prognosis of hypertensive stroke patients]. Nan Fang Yi Ke Da Xue Xue Bao 30: 84-87.
65. Jalal DI, Chonchol M, Chen W, Targher G (2012) Uric Acid as a Target of Therapy in CKD. Am J Kidney Dis.
66. Cheung BM, Ong KL, Tso AW, Cherny SS, Sham PC, et al. (2011) Gamma-glutamyl transferase level predicts the development of hypertension in Hong Kong Chinese. Clin Chim Acta 412: 1326-1331.
67. Benza RL, Barst RJ, Galie N, Frost A, Girgis RE, et al. (2008) Sitaxsentan for the treatment of pulmonary arterial hypertension: a 1-year, prospective, open-label observation of outcome and survival. Chest 134: 775-782.
68. Razavizade M, Jamali R, Arj A, Talari H, (2012) Serum parameters predict the severity of ultrasonographic findings in non-alcoholic fatty liver disease. Hepatobiliary Pancreat Dis Int 11: 513-520.
69. Ma L, Xie C, Ran Y, Liang X, Huang L, et al. (2012) Synthesis, and Biological Evaluation of 5-Benzylidenepyrimidine-2,4,6(1H,3H,5H)-trione Derivatives for the Treatment of Obesity-related Nonalcoholic Fatty Liver Disease. J Med Chem.
70. Ikai E, Ishizaki M, Suzuki Y, Ishida M, Noborizaka Y, et al. (1995) Association between hepatic steatosis, insulin resistance and hyperinsulinaemia as related to hypertension in alcohol consumers and obese people. J Hum Hypertens 9: 101-105.