The DNA methylation profile of PLA2G4C gene promoter in schizophrenia

Psychiatry Research

Volumn 200, Issue 2-3, 2012, Pages 1079-1081

  Xu, Hongqin ^a   Wang, Binbin ^b   Su, Dongmei ^b   Yu, Qiong ^a   Li, Qian ^b   Kou, Changgui ^a   Shi, Jieping ^a   Yu, Yaqin ^a   Ma, Xu ^b,c,d  

^a JILIN UNIVERSITY   (China)

^b National Population and Family Planning Commission   (China)

^c PEKING UNION MEDICAL COLLEGE   (China)

^d WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; TRANSCRIPTION FACTOR SP1;

CPG ISLAND; DNA EXTRACTION; DNA METHYLATION; ENZYME ACTIVATION; GENE ACTIVITY; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; HUMAN; LETTER; PLA2G4C GENE; PRIORITY JOURNAL; PROMOTER REGION; SCHIZOPHRENIA;

CPG ISLANDS; DNA METHYLATION; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GROUP IV PHOSPHOLIPASES A2; HUMANS; MALE; MIDDLE AGED; PROMOTER REGIONS, GENETIC; SCHIZOPHRENIA;

EID: 84872398603     PISSN: 01651781     EISSN: 18727123     Source Type: Journal    
DOI: 10.1016/j.psychres.2012.07.003     Document Type: Letter

References (9)

1. Brown A.S., Susser E.S. Prenatal nutritional deficiency and risk of adult schizophrenia. Schizophrenia Bulletin 2008, 34:1054-1063.
2. Glatt S.J., Jonsson E.G. The Cys allele of the DRD2 Ser311Cys polymorphism has a dominant effect on risk for schizophrenia: evidence from fixed- and random-effects meta-analyses. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2006, 141B:149-154.
3. Kudo S. Methyl-CpG-binding protein MeCP2 represses Sp1-activated transcription of the human leukosialin gene when the promoter is methylated. Molecular and Cellular Biology 1998, 18:5492-5499.
4. Mill J., Tang T., Kaminsky Z., Khare T., Yazdanpanah S., Bouchard L., Jia P., Assadzadeh A., Flanagan J., Schumacher A., Wang S.C., Petronis A. Epigenomic profiling reveals DNA-methylation changes associated with major psychosis. American Journal of Human Genetics 2008, 82:696-711.
5. Naiglin L., Gazagne C., Dallongeville F., Thalamas C., Idder A., Rascol O., Malecaze F., Calvas P. A genome wide scan for familial high myopia suggests a novel locus on chromosome 7q36. Journal of Medical Genetics 2002, 39:118-124.
6. Phillips L.J., Francey S.M., Edwards J., McMurray N. Stress and psychosis: towards the development of new models of investigation. Clinical Psychology Review 2007, 27:307-317.
7. Reynolds E. Vitamin B12, folic acid, and the nervous system. Lancet Neurology 2006, 5:949-960.
8. Song S., Wang W., Hu P. Famine, death, and madness: schizophrenia in early adulthood after prenatal exposure to the Chinese Great Leap Forward Famine. Social Science and Medicine 2009, 68:1315-1321.
9. Tao R., Yu Y., Zhang X., Shi J., Wei J. Lack of genetic association of the PLA2G4C locus with schizophrenia in case-control samples. Psychiatry Genetics 2010, 20:46.