Novel Application of Stem Cell-Derived Neurons to Evaluate the Time- and Dose-Dependent Progression of Excitotoxic Injury

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Gut, Ian M ^a   Beske, Phillip H ^a   Hubbard, Kyle S ^a   Lyman, Megan E ^a   Hamilton, Tracey A ^a   McNutt, Patrick M ^a  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BARIUM ION; CALCIUM ION; MAGNESIUM ION; MICROTUBULE ASSOCIATED PROTEIN 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; TAU PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL DEATH; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOSE RESPONSE; ELECTROPHYSIOLOGY; EMBRYO; EMBRYONIC STEM CELL; ENRICHED GLUTAMATERGIC NEURON; EXCITOTOXICITY; GENE EXPRESSION; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MEDIAN EFFECTIVE CONCENTRATION; MOLECULAR MECHANICS; MOUSE; NECROSIS; NERVE CELL; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NEUROTOXICITY; NONHUMAN; SCANNING ELECTRON MICROSCOPY; SYNAPSE; TIME;

ANIMALS; CALCIUM; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGICAL PROCESSES; GENE EXPRESSION REGULATION; GLUTAMATES; HUMANS; MICE; NEURONS; NEUROTOXINS; PROTEOMICS; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; STEM CELLS; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 84877744858     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064423     Document Type: Article

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