Structural and functional studies of γ-carboxyglutamic acid domains of factor VIIa and activated protein C: Role of magnesium at physiological calcium

Journal of Molecular Biology

Volumn 425, Issue 11, 2013, Pages 1961-1981

  Vadivel, Kanagasabai ^a   Agah, Sayeh ^a   Messer, Amanda S ^a   Cascio, Duilio ^b   Bajaj, Madhu S ^a   Krishnaswamy, Sriram ^c   Esmon, Charles T ^d   Padmanabhan, Kaillathe ^e   Bajaj, S Paul ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^e Michigan State University   (United States)

Author keywords

activated Protein C; factor VIIa; surface plasmon resonance; carboxyglutamic acid domains

Indexed keywords

4 CARBOXYGLUTAMIC ACID; ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 5A; BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 9; CALCIUM ION; ENDOTHELIAL PROTEIN C RECEPTOR; MAGNESIUM ION; THROMBOPLASTIN;

ANTICOAGULATION; ARTICLE; BINDING SITE; BLOOD CLOTTING; CALCIUM BINDING; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LIPID INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

EID: 84877723864     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.02.017     Document Type: Article

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