Membrane association with multiple calcium ions: Vitamin-K-dependent proteins, annexins and pentraxins

Current Opinion in Structural Biology

Volumn 9, Issue 4, 1999, Pages 433-437

  Nelsestuen, Gary L ^a   Ostrowski, Beverly Gaul ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANNEXIN; CALCIUM ION; MEMBRANE PROTEIN; PENTRAXIN; UNCLASSIFIED DRUG; VITAMIN BINDING PROTEIN; VITAMIN K GROUP;

BIOPHYSICS; CRYSTAL STRUCTURE; HUMAN; MEMBRANE BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; REVIEW; STOICHIOMETRY;

EID: 0033178858     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-440X(99)80060-8     Document Type: Article

References (39)

1. Skinner M, Cohen AS: Amyloid P component. Methods Enzymol 1988, 163:523-536.
2. Burgoyne RD, Geisow MJ: The annexin family of calcium-binding proteins. Cell Calcium 1989, 10:1-10.
3. Furie B, Furie BC: The molecular basis of blood coagulation. Cell 1988, 53:505-518.
4. Schwalbe RA, Dahlbäck B, Coe JE, Nelsestuen GL: The pentraxin family of proteins interact specifically with phosphorylcholine and/or phosphorylethanolamine. Biochemistry 1992, 31:4907-4915.
5. Emsley J, White HE, O'Hara BP, Oliva G, Srinivasan N, Tickle IJ, Blundell TL, Pepys MB, Wood SP: Structure of pentameric human serum amyloid P component. Nature 1994, 367:338-345.
6. Bazzi MD, Nelsestuen GL: Highly sequential binding of protein kinase C and related proteins to membranes. Biochemistry 1991, 30:7970-7977.
7. Evans TC Jr, Nelsestuen GL: Calcium and membrane-binding properties of monomeric and multimeric annexin II. Biochemistry 1994, 33:13231-13238.
8. 2+-bridging mechanism and phospholipid head group recognition in the membrane-binding protein annexin V. Nat Struct Biol 1995, 2:968-974.
9. Meers P, Mealy T: Phospholipid determinants for annexin V binding sites and the role of tryptophan 187. Biochemistry 1994, 33:5829-5837.
10. Bazzi MD, Nelsestuen GL: Extensive segregation of acidic phospholipids in membranes induced by protein kinase C and related proteins. Biochemistry 1991, 30:7961-7969.
11. Junker M, Creutz CE: Endonexin (annexin IV)-mediated lateral segregation of phosphatidylglycerol in phosphatidylglycerol/ phosphatidylcholine membranes. Biochemistry 1993, 32:9968-9974.
12. Plager DP, Nelsestuen GL: Direct enthalpy measurements of the calcium-dependent interaction of annexins V and VI with phospholipid vesicles. Biochemistry 1994, 33:13239-13249.
13. 2+ ion and membrane binding structure of the Gla domain of Ca-prothrombin fragment 1. Biochemistry 1992, 31:2554-2566.
14. Banner DW, D'Arcy A, Chene C, Winkler FK, Guha A, Konigsberg WH, Nemerson Y, Kirchhofer D: The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor. Nature 1996, 380:41-46.
15. Freedman SJ, Furie BC, Furie B, Baleja JD: Structure of the calcium ion-bound gamma-carboxyglutamic acid-rich domain of factor IX. Biochemistry 1995, 34:12126-12137.
16. McDonald JF, Evans TC Jr, Emeagwali DB, Hariharan M, Allewell NM, Pusey ML, Shah AM, Nelsestuen GL: Ionic properties of membrane association by vitamin K-dependent proteins: The case for univalency. Biochemistry 1997, 36:15589-15598.
17. Perera L, Darden TA, Pedersen LG: Trans-cis isomerization of praline 22 in bovine prothrombin fragment 1 : A surprising result of structural characterization. Biochemistry 1998, 37:10920-10927.
18. Evans TC Jr, Nelsestuen GL: How important are proline 22 and the 41-45 helical stack to membrane binding by bovine prothrombin? Protein Sci 1996, 5(suppl 1):163Abs.
19. Pedersen L, Charifson P, Darden T, Xiao L, Padmanabhan K, Tulinsky A, Hiskey R: Molecular dynamics simulation of bovine prothrombin fragment 1 in the presence of calcium ions. Biochemistry 1992, 31:8840-8848.
20. McDonald JF, Shah AM, Schwalbe RA, Kisiel W, Dahlback B, Nelsestuen GL: Comparison of naturally occurring vitamin K-dependent proteins: Correlation of amino acid sequences and membrane binding properties suggests a membrane contact site. Biochemistry 1997, 36:5120-5127.
21. Welsch DJ, Nelsestuen GL: Amino terminal alanine functions in a calcium-specific process essential for membrane binding by prothrombin fragment 1. Biochemistry 1988, 27:4939-4945.
22. Weber DJ, Berkowitz P, Panek MG, Huh NW, Pedersen LG, Hiskey RG: Modifications of bovine prothrombin fragment 1 in the presence and absence of Ca (II) ions. Loss of positive cooperativity in Ca(II) ion binding for the modified proteins. J Biol Chem 1992, 267:4564-4569.
23. 2+-dependent properties of the gamma carboxyglutamic acid domain of human anticoagulation protein C and activated protein C. Biochem J 1997, 322:309-315.
24. Seshadri T, Skrzypckak-Jankum E, Yin M, Tulinsky A: Differences in the metal ion structure between Sr- and Ca-prothrombin fragment 1. Biochemistry 1994, 33:1087-1092.
25. Ratcliffe JV, Furie B, Furie BC: The importance of specific gamma-carboxyglutamic acid residues in prothrombin. Evaluation by site-specific mutagenesis. J Biol Chem 1993, 268:24339-24345.
26. Larson PJ, Camire RM, Wong D, Fasano NC, Monroe DM, Tracy PB, High KA: Structure/function analyses of recombinant variants of human factor Xa: Factor Xa incorporation into prothrombinase on the thrombin-activated platelet surface is not mimicked by synthetic phospholipid vesicles. Biochemistry 1998, 37:5029-5038.
27. Resnick RM, Nelsestuen GL: Prothrombin-membrane interaction. Effects of ionic strength, pH and temperature. Biochemistry 1980, 19:3028-3033.
28. Shen L, Shah AM, Dahlback B, Nelsestuen GL: Enhancing the activity of protein C by mutagenesis to improve the membrane-binding site: Studies related to proline-10. Biochemistry 1997, 36:16025-16031.
29. Shah AM, Kisiel W, Foster DC, Nelsestuen GL: Manipulation of the membrane binding site of vitamin K-dependent proteins: Enhanced biological function of human factor VII. Proc Natl Acad Sci USA 1999, 4229-4234. The ability to enhance membrane affinity by site-directed mutation is an important step towards future work examining membrane function in the enzymatic reaction, the location of the membrane-contact site and may even offer better proteins for therapeutic purposes.
30. Shen L, Shah AM, Dahlback B, Nelsestuen GL: Enhancement of human protein C function by site-directed mutagenesis of the gamma-carboxyglutamic acid domain. J Biol Chem 1998, 273:31086-31091. Using protein C with improved membrane affinity offers a tool for the study of reaction mechanism in coagulation and may provide improved proteins for therapeutic purposes.
31. Freedman SJ, Blostein MD, Baleja JD, Jacobs M, Furie GC, Furie B: Identification of the phospholipid binding site in the vitamin K-dependent blood coagulation protein factor IX. J Biol Chem 1996, 271:16227-16236.
32. Sunnerhagen M, Forsen S, Hoffren AM, Drakenberg T, Teleman O, Stenflo J: Structure of the Ca(2+)-free Gla domain sheds light on membrane binding of blood coagulation proteins. Nat Struct Biol 1995, 2:504-509.
33. Lu Y, Nelsestuen GL: Dynamic features of prothrombin interaction with phospholipid vesicles of different size and composition: Implications for protein-membrane contact. Biochemistry 1996, 36:8193-8200.
34. Mayer LD, Nelsestuen GL, Brockman HL: Prothrombin association with phospholipid monolayers. Biochemistry 1983, 22:316-321.
35. Christiansen WT, Jalbert LR, Robertson RM, Jhingan A, Prorok M, Castellino FJ: Hydrophobic amino acid residues of human anticoagulation protein C that contribute to its functional binding to phospholipid vesicles. Biochemistry 1995, 34:10376-10382.
36. Nelsestuen GL: Basis for prothrombin-membrane binding. In Current Advances in Vitamin K Research. Amsterdam: Elsevier Publishing; 1998:335-339.
37. Jalbert LR, Chan JC, Christiansen WT, Castellino FJ: The hydrophobic nature of residue-5 of human protein C is a major determinant of its functional interactions with acidic phospholipid vesicles. Biochemistry 1996, 35:7093-7099.
38. Zhang L, Castellino FJ: The binding energy of human coagulation protein C to acidic phospholipid vesicles contains a major contribution from leucine 5 in the gamma-carboxyglutamic acid domain. J Biol Chem 1994, 269:3590-3595.
39. Nicholls A, Sharp KA, Honig B: Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins 1991, 11:281-296.