A Soft Coral-Derived Compound, 11-epi-Sinulariolide Acetate Suppresses Inflammatory Response and Bone Destruction in Adjuvant-Induced Arthritis

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Lin, Yen You ^a   Jean, Yen Hsuan ^b   Lee, Hsin Pai ^a,b   Chen, Wu Fu ^c   Sun, Yu Min ^a   Su, Jui Hsin ^d,e   Lu, Yi ^a   Huang, Shi Ying ^a   Hung, Han Chun ^a   Sung, Ping Jyun ^d,e   Sheu, Jyh Horng ^a   Wen, Zhi Hong ^a  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^b PINGTUNG CHRISTIAN HOSPITAL   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^d NATIONAL DONG HWA UNIVERSITY   (Taiwan)

^e NATIONAL MUSEUM OF MARINE BIOLOGY AND AQUARIUM   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

11 EPI SINULARIOLIDE ACETATE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ANTIINFLAMMATORY AGENT; CATHEPSIN K; CYCLOOXYGENASE 3; GELATINASE B; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; BONE DESTRUCTION; CONTROLLED STUDY; DRUG EFFICACY; DRUG SCREENING; MACROPHAGE; MALE; MARINE SPECIES; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RAT; SINULARIA QUERCIFORMIS; SOFT CORAL;

ACID PHOSPHATASE; ANIMALS; ANTHOZOA; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS, EXPERIMENTAL; BONE RESORPTION; CATHEPSIN K; DITERPENES; DRUG ADMINISTRATION SCHEDULE; FEMALE; GENE EXPRESSION; HINDLIMB; INFLAMMATION; INJECTIONS, SUBCUTANEOUS; ISOENZYMES; MATRIX METALLOPROTEINASE 9; RATS; RATS, INBRED LEW; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84877677868     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0062926     Document Type: Article

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