Inhibiting effects of Leflunomide metabolite on overexpression of CD147, MMP-2 and MMP-9 in PMA differentiated THP-1 cells

European Journal of Pharmacology

Volumn 670, Issue 1, 2011, Pages 304-310

  Huang, Jian Lin ^a   Wu, Shi Yao ^a   Xie, Xu Jing ^a   Wang, Ming Xia ^a   Zhu, Shangling ^a   Gu, Jie Ruo ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Cluster of differentiation 147; Human monocytic cell line THP 1; Leflunomide metabolite A771726; Matrix metalloproteinase

Indexed keywords

CD147 ANTIGEN; GELATINASE A; GELATINASE B; LEFLUNOMIDE; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; TERIFLUNOMIDE;

ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL STRAIN; CELL STRAIN THP 1; CELL SURFACE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ZYMOGRAPHY;

ANILINE COMPOUNDS; ANTIGENS, CD147; CELL DIFFERENTIATION; CELL LINE; COLLAGENASES; GELATIN; GENE EXPRESSION REGULATION; HUMANS; HYDROXYBUTYRATES; ISOXAZOLES; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MONOCYTES; RNA, MESSENGER; TETRADECANOYLPHORBOL ACETATE;

EID: 80054752289     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.07.045     Document Type: Article

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