Antioxidant polymeric nanoparticles as novel therapeutics for airway inflammatory diseases

International Journal of Pharmaceutics

Volumn 450, Issue 1-2, 2013, Pages 87-94

  Yoo, Donghyuck ^a   Guk, Kyeonghye ^a   Kim, Hyungmin ^a   Khang, Gilson ^a   Wu, Dongmei ^a   Lee, Dongwon ^a  

^a Chonbuk National University   (South Korea)

Author keywords

Antioxidant; Asthma; Biodegradable polymers; Nanoparticles; Pulmonary drug delivery

Indexed keywords

ANTIASTHMATIC AGENT; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CYCLOOXYGENASE 2; HPOX; HYDROGEN PEROXIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 4; NANOPARTICLE; OXALIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ASTHMA; CONTROLLED STUDY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ALLERGENS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; ASTHMA; BENZYL ALCOHOLS; BRONCHOALVEOLAR LAVAGE FLUID; CYTOKINES; MICE; NANOPARTICLES; OVALBUMIN; POLYMERS;

EID: 84877675412     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.04.028     Document Type: Article

References (30)

1. S.A. Cryan Carrier-based strategies for targeting protein and peptide drugs to the lungs AAPS J. 7 2005 E20 E41
2. L.A. Dailey, N. Jekel, L. Fink, T. Gessler, T. Schmehl, M. Wittmar, T. Kissel, and W. Seeger Investigation of the proinflammatory potential of biodegradable nanoparticle drug delivery systems in the lung Toxicol. Appl. Pharmacol. 215 2006 100 108
3. L.A. Dailey, T. Schmehl, T. Gessler, M. Wittmar, F. Grimminger, W. Seeger, and T. Kissel Nebulization of biodegradable nanoparticles: impact of nebulizer technology and nanoparticle characteristics on aerosol features J. Control. Release 86 2003 131 144
4. P. Dames, B. Gleich, A. Flemmer, K. Hajek, N. Seidl, F. Wiekhorst, D. Eberbeck, I. Bittmann, C. Bergemann, T. Weyh, L. Trahms, J. Rosenecker, and C. Rudolph Targeted delivery of magnetic aerosol droplets to the lung Nat. Nanotechnol. 2 2007 495 499
5. E. Descamps, M. Petrault-Laprais, P. Maurois, N. Pages, P. Bac, R. Bordet, and J. Vamecq Experimental stroke protection induced by 4-hydroxybenzyl alcohol is cancelled by bacitracin Neurosci. Res. 64 2009 137 142
6. J. Fiegel, H. Fu, and J. Hanes Poly(ether-anhydride) dry powder aerosols for sustained drug delivery in the lungs J. Control. Release 96 2004 411 423
7. V.F. Fiore, M.C. Lofton, S. Roser-Page, S.C. Yang, J. Roman, N. Murthy, and T.H. Barker Polyketal microparticles for therapeutic delivery to the lung Biomaterials 31 2010 810 817
8. A. Grenha, C. Remunan-Lopez, E.L.S. Carvalho, and B. Seijo Microspheres containing lipid/chitosan nanoparticles complexes for pulmonary delivery of therapeutic proteins Eur. J. Pharm. Biopharm. 69 2008 83 93
9. A. Grenha, B. Seijo, and C. Remunan-Lopez Microencapsulated chitosan nanoparticles for lung protein delivery Eur. J. Pharm. Sci. 25 2005 427 437
10. B.G. Jones, P.A. Dickinson, M. Gumbleton, and I.W. Kellaway The inhibition of phagocytosis of respirable microspheres by alveolar and peritoneal macrophages Int. J. Pharm. 236 2002 65 79
11. R. Kandasamy, S.J. Park, S. Boyapalle, S. Mohapatra, G.R. Hellermann, R.F. Lockey, and S.S. Mohapatra Isatin down-regulates expression of atrial natriuretic peptide receptor a and inhibits airway inflammation in a mouse model of allergic asthma Int. Immunopharmacol. 10 2010 218 225
12. H. Kim, H. Park, J. Lee, T.H. Kim, E.S. Lee, K.T. Oh, K.C. Lee, and Y.S. Youn Highly porous large poly(lactic-co-glycolic acid) microspheres adsorbed with palmityl-acylated exendin-4 as a long-acting inhalation system for treating diabetes Biomaterials 32 2011 1685 1693
13. H.J. Kim, I.K. Hwang, and M.H. Won Vanillin, 4-hydroxybenzyl aldehyde and 4-hydroxybenzyl alcohol prevent hippocampal Ca1 cell death following global ischemia Brain Res. 1181 2007 130 141
14. S. Kim, H. Park, Y. Song, D. Hong, O. Kim, E. Jo, G. Khang, and D. Lee Reduction of oxidative stress by P-hydroxybenzyl alcohol-containing biodegradable polyoxalate nanoparticulate antioxidant Biomaterials 32 2011 3021 3029
15. S. Kim, K. Seong, O. Kim, H. Seo, M. Lee, G. Khang, and D. Lee Polyoxalate nanoparticles as a biodegradable and biocompatible drug delivery vehicle Biomacromolecules 11 2010 555 560
16. N.R. Labiris, and M.B. Dolovich Pulmonary drug delivery. Part II: the role of inhalant delivery devices and drug formulations in therapeutic effectiveness of aerosolized medications Br. J. Clin. Pharmacol. 56 2003 600 612
17. D.W. Lee, S.A. Shirley, R.F. Lockey, and S.S. Mohapatra Thiolated chitosan nanoparticles enhance anti-inflammatory effects of intranasally delivered theophylline Respir. Res. 2006 7
18. J.Y. Lee, Y.W. Jang, H.S. Kang, H. Moon, S.S. Sim, and C.J. Kim Anti-inflammatory action of phenolic compounds from Gastrodia elata root Arch. Pharmacal Res. 29 2006 849 858
19. E.J. Lim, H.J. Kang, H.J. Jung, and E.H. Park Anti-angiogenic, anti-inflammatory and anti-nociceptive activity of 4-hydroxybenzyl alcohol J. Pharm. Pharmacol. 59 2007 1235 1240
20. U. Mabalirajan, T. Ahmad, G.D. Leishangthem, D.A. Joseph, A.K. Dinda, A. Agrawal, and B. Ghosh Beneficial effects of high dose of l-arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma J. Allergy Clin. Immunol. 125 2010 626 635
21. D.O. Moon, M.O. Kim, H.J. Lee, Y.H. Choi, Y.M. Park, M.S. Heo, and G.Y. Kim Curcumin attenuates ovalbumin-induced airway inflammation by regulating nitric oxide Biochem. Biophys. Res. Commun. 375 2008 275 279
22. J.J. Moreno Effect of olive oil minor components on oxidative stress and arachidonic acid mobilization and metabolism by macrophages raw 264.7 Free Radic. Biol. Med. 35 2003 1073 1081
23. Y.J. Oh, J. Lee, J.Y. Seo, T. Rhim, S.H. Kim, H.J. Yoon, and K.Y. Lee Preparation of budesonide-loaded porous PLGA microparticles and their therapeutic efficacy in a murine asthma model J. Control. Release 150 2011 56 62
24. H. Park, S. Kim, Y. Song, K. Seung, D. Hong, G. Khang, and D. Lee Antioxidant and anti-inflammatory activities of hydroxybenzyl alcohol releasing biodegradable polyoxalate nanoparticles Biomacromolecules 11 2010 2103 2108
25. G. Ramesh, S.K. Jindal, N.K. Ganguly, and V. Dhawan Increased nitric oxide production by neutrophils in bronchial asthma Eur. Respir. J. 17 2001 868 871
26. S.A. Shoyele, and S. Cawthome Particle engineering techniques for inhaled biopharmaceuticals Adv. Drug Deliv. Rev. 58 2006 1009 1029
27. J.C. Sy, G. Seshadri, S.C. Yang, M. Brown, T. Oh, S. Dikalov, N. Murthy, and M.E. Davis Sustained release of a P38 inhibitor from non-inflammatory microspheres inhibits cardiac dysfunction Nat. Mater. 7 2008 863 869
28. C.K. Wong, C.Y. Ho, F.W.S. Ko, C.H.S. Chan, A.S.S. Ho, D.S.C. Hui, and C.W.K. Lam Proinflammatory cytokines (Il-17, Il-6, Il-18 and Il-12) and Th cytokines (Ifn-gamma, Il-4, Il-10 and Il-13) in patients with allergic asthma Clin. Exp. Immunol. 125 2001 177 183
29. Y. Yang, N. Bajaj, P. Xu, K. Ohn, M.D. Tsifansky, and Y. Yeo Development of highly porous large PLGA microparticles for pulmonary drug delivery Biomaterials 30 2009 1947 1953
30. S.J. Yu, J.R. Kim, C.K. Lee, J.E. Han, J.H. Lee, H.S. Kim, J.H. Hong, and S.G. Kang Gastrodia elata Blume and an active component, P-hydroxybenzyl alcohol reduce focal ischemic brain injury through antioxidant related gene expressions Biol. Pharm. Bull. 28 2005 1016 1020