N-Terminal Helix-Cap in α-Helix 2 Modulates β-State Misfolding in Rabbit and Hamster Prion Proteins

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Sweeting, Braden ^a,b   Brown, Eric ^a,c   Khan, M Qasim ^a,b   Chakrabartty, Avijit ^a,b   Pai, Emil F ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; PRION PROTEIN; SERINE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; GEL PERMEATION CHROMATOGRAPHY; HAMSTER; HYDROGEN BOND; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; PROTEIN UNFOLDING; RABBIT; STRUCTURE ANALYSIS; WILD TYPE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ASPARAGINE; CIRCULAR DICHROISM; CRICETINAE; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PRION DISEASES; PRIONS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RABBITS; SEQUENCE ALIGNMENT; SERINE; UREA;

EID: 84877609635     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063047     Document Type: Article

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