Tumor Environmental Factors Glucose Deprivation and Lactic Acidosis Induce Mitotic Chromosomal Instability - An Implication in Aneuploid Human Tumors

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Dai, Chunyan ^a   Sun, Feifei ^b   Zhu, Chunpeng ^a   Hu, Xun ^a  

^a THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANEUPLOIDY; ANIMAL CELL; ARTICLE; CELL STRAIN HCT116; CELL STRAIN MCF 7; CENTROSOME; CHROMOSOMAL INSTABILITY; CONTROLLED STUDY; DNA DAMAGE; GLUCOSE DEPRIVATION; HUMAN; HUMAN CELL; LACTIC ACIDOSIS; M PHASE CELL CYCLE CHECKPOINT; MICRONUCLEUS; MITOSIS; NONHUMAN; ONCOLOGICAL PARAMETERS; TUMOR MICROENVIRONMENT;

ACIDOSIS, LACTIC; ANEUPLOIDY; ANIMALS; CELL LINE, TUMOR; CENTROSOME; CHROMOSOMAL INSTABILITY; DISEASE MODELS, ANIMAL; DNA DAMAGE; GENE AMPLIFICATION; GLUCOSE; HUMANS; MICE; MITOSIS; NEOPLASMS; STRESS, PHYSIOLOGICAL;

EID: 84877597763     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063054     Document Type: Article

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