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Volumn 133, Issue 6, 2006, Pages 1183-1192

Roles for Dnmt3b in mammalian development: A mouse model for the ICF syndrome

Author keywords

Apoptosis; DNA methylation; Dnmt3b; ICF syndrome; T cell

Indexed keywords

DNA METHYLTRANSFERASE 3B;

EID: 33645735015     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.02293     Document Type: Article
Times cited : (146)

References (44)
  • 1
    • 0035943709 scopus 로고    scopus 로고
    • Dnmt3a Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin
    • Bachman, K. E., Rountree, M. R. and Baylin, S. B. (2001). Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin. J. Biol. Chem. 276, 32282-32287.
    • (2001) J. Biol. Chem. , vol.276 , pp. 32282-32287
    • Bachman, K.E.1    Rountree, M.R.2    Baylin, S.B.3
  • 2
    • 0029026984 scopus 로고
    • ICF syndrome (immunodeficiency centromeric instability facial anomalies): Investigation of heterochromatin abnormalities review of clinical outcome
    • Brown, D. C., Grace, E., Sumner, A. T., Edmunds, A. T. and Ellis, P. M. (1995). ICF syndrome (immunodeficiency, centromeric instability and facial anomalies): investigation of heterochromatin abnormalities and review of clinical outcome. Hum. Genet. 96, 411-416.
    • (1995) Hum. Genet. , vol.96 , pp. 411-416
    • Brown, D.C.1    Grace, E.2    Sumner, A.T.3    Edmunds, A.T.4    Ellis, P.M.5
  • 3
    • 0037340215 scopus 로고    scopus 로고
    • Selective stable demethylation of the interleukin-2 gene enhances transcription by an active process
    • Bruniquel, D. and Schwartz, R. H. (2003). Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process. Nat. Immunol. 4, 235-240.
    • (2003) Nat. Immunol. , vol.4 , pp. 235-240
    • Bruniquel, D.1    Schwartz, R.H.2
  • 4
    • 0023890497 scopus 로고
    • Variable immunodeficiency with abnormal condensation of the heterochromatin of chromosomes 1, 9, and 16
    • Carpenter, N. J., Filipovich, A., Blaese, R. M., Carey, T. L. and Berkel, A.I. (1988). Variable immunodeficiency with abnormal condensation of the heterochromatin of chromosomes 1, 9, and 16. J. Pediatr 112, 757-760.
    • (1988) J. Pediatr , vol.112 , pp. 757-760
    • Carpenter, N.J.1    Filipovich, A.2    Blaese, R.M.3    Carey, T.L.4    Berkel, A.I.5
  • 5
    • 0037064088 scopus 로고    scopus 로고
    • A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin its expression correlates with active de novo methylation
    • Chen, T., Ueda, Y., Xie, S. and Li, E. (2002). A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation. J. Biol. Chem. 277, 38746-38754.
    • (2002) J. Biol. Chem. , vol.277 , pp. 38746-38754
    • Chen, T.1    Ueda, Y.2    Xie, S.3    Li, E.4
  • 6
    • 0042132027 scopus 로고    scopus 로고
    • Establishment maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a Dnmt3b
    • Chen, T., Ueda, Y., Dodge, J. E., Wang, Z. and Li, E. (2003). Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol. Cell. Biol. 23, 5594-5605.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5594-5605
    • Chen, T.1    Ueda, Y.2    Dodge, J.E.3    Wang, Z.4    Li, E.5
  • 7
    • 4744366752 scopus 로고    scopus 로고
    • The PWWP domain of Dnmt3a Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin
    • Chen, T., Tsujimoto, N. and Li, E. (2004). The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin. Mol. Cell. Biol. 24, 9048-9058.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9048-9058
    • Chen, T.1    Tsujimoto, N.2    Li, E.3
  • 8
    • 0035890090 scopus 로고    scopus 로고
    • Lsh a member of the SNF2 family is required for genome-wide methylation
    • Dennis, K., Fan, T., Geiman, T., Yan, Q. and Muegge, K. (2001). Lsh, a member of the SNF2 family, is required for genome-wide methylation. Genes Dev 15, 2940-2944.
    • (2001) Genes Dev , vol.15 , pp. 2940-2944
    • Dennis, K.1    Fan, T.2    Geiman, T.3    Yan, Q.4    Muegge, K.5
  • 9
    • 24044481947 scopus 로고    scopus 로고
    • Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation chromosomal instability spontaneous immortalization
    • Dodge, J. E., Okano, M., Dick, F., Tsujimoto, N., Chen, T, Wang, S., Ueda, Y., Dyson, N. and Li, E. (2005). Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization. J. Biol. Chem. 280, 17986-17991.
    • (2005) J. Biol. Chem. , vol.280 , pp. 17986-17991
    • Dodge, J.E.1    Okano, M.2    Dick, F.3    Tsujimoto, N.4    Chen, T.5    Wang, S.6    Ueda, Y.7    Dyson, N.8    Li, E.9
  • 10
    • 0142216231 scopus 로고    scopus 로고
    • The ICF syndrome a DNA methyltransferase 3B deficiency immunodeficiency disease
    • Ehrlich, M. (2003). The ICF syndrome, a DNA methyltransferase 3B deficiency and immunodeficiency disease. Clin. Immunol. 109, 17-28.
    • (2003) Clin. Immunol. , vol.109 , pp. 17-28
    • Ehrlich, M.1
  • 12
    • 0025346267 scopus 로고
    • Fragility of the centromeric region of chromosome 1 associated with combined immunodeficiency in siblings. A recessively inherited entity?
    • Fasth, A., Forestier, E., Holmberg, E., Holmgren, G., Nordenson, I., Soderstrom, T. and Wahlstrom, J. (1990). Fragility of the centromeric region of chromosome 1 associated with combined immunodeficiency in siblings. A recessively inherited entity? Acta Paediatr Scand. 79, 605-612.
    • (1990) Acta Paediatr Scand. , vol.79 , pp. 605-612
    • Fasth, A.1    Forestier, E.2    Holmberg, E.3    Holmgren, G.4    Nordenson, I.5    Soderstrom, T.6    Wahlstrom, J.7
  • 13
    • 0032490674 scopus 로고    scopus 로고
    • Distinct methylation of the interferon gamma (IFN-gamma) interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: Regional IFN-gamma promoter demethylation mRNA expression are heritable in CD44 (high) CD8+ T cells
    • Fitzpatrick, D. R., Shirley, K. M., McDonald, L. E., Bielefeldt-Ohmann, H., Kay, G. F. and Kelso, A. (1998). Distinct methylation of the interferon gamma (IFN-gamma) and interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: regional IFN-gamma promoter demethylation and mRNA expression are heritable in CD44 (high) CD8+ T cells. J. Exp. Med. 188, 103-117.
    • (1998) J. Exp. Med. , vol.188 , pp. 103-117
    • Fitzpatrick, D.R.1    Shirley, K.M.2    McDonald, L.E.3    Bielefeldt-Ohmann, H.4    Kay, G.F.5    Kelso, A.6
  • 15
    • 0034712755 scopus 로고    scopus 로고
    • Lsh an SNF2/helicase family member is required for proliferation of mature T lymphocytes
    • Geiman, T M. and Muegge, K. (2000). Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes. Proc. Natl. Acad. Sci. USA 97, 4772-4777.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 4772-4777
    • Geiman, T.M.1    Muegge, K.2
  • 17
    • 0028001362 scopus 로고
    • The Ikaros gene is required for the development of all lymphoid lineages
    • Georgopoulos, K., Bigby, M., Wang, J. H., Molnar, A., Wu, R, Winandy, S. and Sharpe, A. (1994). The Ikaros gene is required for the development of all lymphoid lineages. Cell 79, 143-156.
    • (1994) Cell , vol.79 , pp. 143-156
    • Georgopoulos, K.1    Bigby, M.2    Wang, J.H.3    Molnar, A.4    Wu, R.5    Winandy, S.6    Sharpe, A.7
  • 18
    • 0037036468 scopus 로고    scopus 로고
    • Molecular enzymology of the catalytic domains of the Dnmt3a Dnmt3b DNA methyltransferases
    • Gowher, H. and Jeltsch, A. (2002). Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases. J. Biol. Chem. 277, 20409-20414.
    • (2002) J. Biol. Chem. , vol.277 , pp. 20409-20414
    • Gowher, H.1    Jeltsch, A.2
  • 20
    • 0036333103 scopus 로고    scopus 로고
    • Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice
    • Hata, K., Okano, M., Lei, H. and Li, E. (2002). Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development 129, 1983-1993.
    • (2002) Development , vol.129 , pp. 1983-1993
    • Hata, K.1    Okano, M.2    Lei, H.3    Li, E.4
  • 21
    • 0000038810 scopus 로고
    • Selective somatic pairing fragility at 1q12 in a boy with common variable immunodeficiency
    • Hulten, M. (1978). Selective somatic pairing and fragility at 1q12 in a boy with common variable immunodeficiency. Clin. Genet. 14, 294.
    • (1978) Clin. Genet. , vol.14 , pp. 294
    • Hulten, M.1
  • 23
    • 3042584653 scopus 로고    scopus 로고
    • Essential role for de novo DNA methyltransferase Dnmt3a in paternal maternal imprinting
    • Kaneda, M., Okano, M., Hata, K., Sado, T., Tsujimoto, N., Li, E. and Sasaki, H. (2004). Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature 429, 900-903.
    • (2004) Nature , vol.429 , pp. 900-903
    • Kaneda, M.1    Okano, M.2    Hata, K.3    Sado, T.4    Tsujimoto, N.5    Li, E.6    Sasaki, H.7
  • 24
    • 0036683055 scopus 로고    scopus 로고
    • Cooperation communication between the human maintenance de novo DNA (cytosine-5) methyltransferases
    • Kim, G. D., Ni, J., Kelesoglu, N., Roberts, R. J. and Pradhan, S. (2002). Cooperation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases. EMBO J. 21, 4183-4195.
    • (2002) EMBO J. , vol.21 , pp. 4183-4195
    • Kim, G.D.1    Ni, J.2    Kelesoglu, N.3    Roberts, R.J.4    Pradhan, S.5
  • 28
    • 0029803192 scopus 로고    scopus 로고
    • De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells
    • Lei, H., Oh, S. P., Okano, M., Juttermann, R., Goss, K. A., Jaenisch, R. and Li, E. (1996). De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells. Development 122, 3195-3205.
    • (1996) Development , vol.122 , pp. 3195-3205
    • Lei, H.1    Oh, S.P.2    Okano, M.3    Juttermann, R.4    Goss, K.A.5    Jaenisch, R.6    Li, E.7
  • 29
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li, E., Bestor, T. H. and Jaenisch, R. (1992). Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 31
    • 0023848337 scopus 로고
    • Immunodeficiency centromeric heterochromatin instability of chromosomes 1, 9, and 16 facial anomalies: The ICF syndrome
    • Maraschio, P, Zuffardi, O., Dalla Fior, T. and Tiepolo, L. (1988). Immunodeficiency, centromeric heterochromatin instability of chromosomes 1, 9, and 16, and facial anomalies: the ICF syndrome. J. Med. Genet. 25, 173-180.
    • (1988) J. Med. Genet. , vol.25 , pp. 173-180
    • Maraschio, P.1    Zuffardi, O.2    Dalla Fior, T.3    Tiepolo, L.4
  • 32
    • 0031860739 scopus 로고    scopus 로고
    • Cloning characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
    • Okano, M., Xie, S. and Li, E. (1998). Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat. Genet 19, 219-220.
    • (1998) Nat. Genet , vol.19 , pp. 219-220
    • Okano, M.1    Xie, S.2    Li, E.3
  • 33
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a Dnmt3b are essential for de novo methylation mammalian development
    • Okano, M., Bell, D. W., Haber, D. A. and Li, E. (1999). DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 36
    • 0018672228 scopus 로고
    • Multibranched chromosomes 1, 9, and 16 in a patient with combined IgA IgE deficiency
    • Tiepolo, L., Maraschio, P., Gimelli, G., Cuoco, C., Gargani, G. F. and Romano, C. (1979). Multibranched chromosomes 1, 9, and 16 in a patient with combined IgA and IgE deficiency. Hum. Genet. 51, 127-137.
    • (1979) Hum. Genet. , vol.51 , pp. 127-137
    • Tiepolo, L.1    Maraschio, P.2    Gimelli, G.3    Cuoco, C.4    Gargani, G.F.5    Romano, C.6
  • 38
    • 0032489848 scopus 로고    scopus 로고
    • Formation of the atrioventricular septal structures in the normal mouse
    • Webb, S., Brown, N. A. and Anderson, R. H. (1998). Formation of the atrioventricular septal structures in the normal mouse. Circ. Res. 82, 645-656.
    • (1998) Circ. Res. , vol.82 , pp. 645-656
    • Webb, S.1    Brown, N.A.2    Anderson, R.H.3
  • 40
    • 0028866897 scopus 로고
    • A dominant mutation in the lkaros gene leads to rapid development of leukemia lymphoma
    • Winandy, S., Wu, P. and Georgopoulos, K. (1995). A dominant mutation in the lkaros gene leads to rapid development of leukemia and lymphoma. Cell 83, 289-299.
    • (1995) Cell , vol.83 , pp. 289-299
    • Winandy, S.1    Wu, P.2    Georgopoulos, K.3
  • 41
    • 0032769445 scopus 로고    scopus 로고
    • Cloning expression chromosome locations of the human DNMT3 gene family
    • Xie, S., Wang, Z., Okano, M., Nogami, M., Li, Y., He, W. W., Okumura, K. and Li, E. (1999). Cloning, expression and chromosome locations of the human DNMT3 gene family. Gene 236, 87-95.
    • (1999) Gene , vol.236 , pp. 87-95
    • Xie, S.1    Wang, Z.2    Okano, M.3    Nogami, M.4    Li, Y.5    He, W.W.6    Okumura, K.7    Li, E.8
  • 43
    • 0141628697 scopus 로고    scopus 로고
    • Association of Lsh a regulator of DNA methylation with pericentromeric heterochromatin is dependent on intact heterochromatin
    • Yan, Q., Cho, E., Lockett, S. and Muegge, K. (2003a). Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin. Mol. Cell. BioL 23, 8416-8428.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 8416-8428
    • Yan, Q.1    Cho, E.2    Lockett, S.3    Muegge, K.4
  • 44
    • 0141642008 scopus 로고    scopus 로고
    • Lsh a modulator of CpG methylation is crucial for normal histone methylation
    • Yan, Q., Huang, J., Fan, T., Zhu, H. and Muegge, K. (2003b). Lsh, a modulator of CpG methylation, is crucial for normal histone methylation. EMBO J. 22, 5154-5162.
    • (2003) EMBO J. , vol.22 , pp. 5154-5162
    • Yan, Q.1    Huang, J.2    Fan, T.3    Zhu, H.4    Muegge, K.5


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