Prostaglandin E2-induced intercellular adhesion molecule-1 expression is mediated by cAMP/Epac signalling modules in bEnd.3 brain endothelial cells

British Journal of Pharmacology

Volumn 169, Issue 3, 2013, Pages 604-618

  Park, Tae Yeop ^a   Baik, Eun Joo ^a   Lee, Soo Hwan ^a  

^a Ajou University School of Medicine   (South Korea)

Author keywords

cerebrovascular endothelial cell; EP4 receptor; exchange protein activated by cAMP; intercellular adhesion molecule 1; nuclear factor B; PI3K Akt; prostaglandin E2

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; 8 (4-CHLOROPHENYLTHIO) 2' O METHYL ADENOSINE 3',5' CYCLIC MONOPHOSPHATE; ANTIPORTER; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BUCLADESINE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE ACTIVATOR; CYCLIC AMP DERIVATIVE; ENZYME ACTIVATOR; EXCHANGE PROTEIN ACTIVATED BY CYCLIC AMP; FORSKOLIN; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LUCIFERASE; N6 BENZOYLADENOSINE 3',5' CYCLIC MONOPHOSPHATE; ONO AE2 227; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E RECEPTOR 4 ANTAGONIST; PROSTAGLANDIN E2; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PROTEIN KINASE B INHIBITOR VIII; RECEPTOR BLOCKING AGENT; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN BLOOD VESSEL; CELL ADHESION; CELL NUCLEUS; ENDOTHELIUM CELL; ENZYME ASSAY; ENZYME PHOSPHORYLATION; GENE ACTIVITY; GENE SILENCING; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; INFLAMMATION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN TRANSPORT; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; VASCULAR ENDOTHELIUM;

ANIMALS; BRAIN; CELL ADHESION; CELL LINE; CELLS, CULTURED; CYCLIC AMP; DINOPROSTONE; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GENE SILENCING; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MICE; MICE, INBRED C57BL; MONOCYTES; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; SECOND MESSENGER SYSTEMS; UP-REGULATION; VASODILATOR AGENTS;

EID: 84877574716     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12103     Document Type: Article

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