Optimization of brain targeted chitosan nanoparticles of Rivastigmine for improved efficacy and safety

International Journal of Biological Macromolecules

Volumn 59, Issue , 2013, Pages 72-83

  Nagpal, Kalpana ^a   Singh, S K ^a   Mishra, D N ^a  

^a GURU JAMBHESHWAR UNIVERSITY OF SCIENCE AND TECHNOLOGY   (India)

Author keywords

Chitosan; Elevated plus maze; Maximum tolerated dose; Morris water maze; Optimization; Rivastigmine tartrate

Indexed keywords

CHITOSAN; NANOPARTICLE; PIRACETAM; PLACEBO; POLYSORBATE 80; RIVASTIGMINE;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG FORMULATION; DRUG RELEASE; DRUG SAFETY; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM TOLERATED DOSE; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PROCESS OPTIMIZATION; RAT; ZETA POTENTIAL;

EID: 84877344185     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2013.04.024     Document Type: Article

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