Catalpol improves cholinergic function and reduces inflammatory cytokines in the senescent mice induced by d-galactose

Food and Chemical Toxicology

Volumn 58, Issue , 2013, Pages 50-55

  Zhang, Xiuli ^a   Jin, Changzhu ^a   Li, Yachen ^b   Guan, Shui ^c   Han, Fang ^a   Zhang, Shuping ^a  

^a BINZHOU MEDICAL UNIVERSITY   (China)

^b DALIAN MEDICAL UNIVERSITY   (China)

^c DALIAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Aging; Catalpol; Cholinergic system; Inflammatory cytokines

Indexed keywords

ACETYLCHOLINESTERASE; ADVANCED GLYCATION END PRODUCT; CATALPOL; CHOLINE ACETYLTRANSFERASE; GALACTOSE; INTERLEUKIN 1BETA; MUSCARINIC M1 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN LEVEL; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG ISOLATION; DRUG MEGADOSE; ENZYME ACTIVITY; FEMALE; FOREBRAIN; HIPPOCAMPUS; LOW DRUG DOSE; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; PHYTOCHEMISTRY; PLANT ROOT; PROTEIN EXPRESSION; REHMANNIA; SENESCENCE;

AGING; CATALPOL; CHOLINERGIC SYSTEM; INFLAMMATORY CYTOKINES;

ACETYLCHOLINESTERASE; AGING; ANIMALS; BRAIN; CHOLINE O-ACETYLTRANSFERASE; CYTOKINES; FEMALE; GALACTOSE; INFLAMMATION MEDIATORS; IRIDOID GLUCOSIDES; MALE; MICE;

EID: 84877343109     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.04.006     Document Type: Article

References (32)

1. Basta G. Receptor for advanced glycation endproducts and atherosclerosis: from basic mechanisms to clinical implications. Atherosclerosis 2008, 196:9-21.
2. Block M.L., Hong J.S. Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Prog. Neurobiol. 2005, 76:77-98.
3. Bohnen N.I., Albin R.L. The cholinergic system and Parkinson disease. Behav. Brain Res. 2011, 221:564-573.
4. Borlongan C.V., Sumaya I.C., Moss D.E. Methanesulfonyl fluoride, an acetylcholinesterase inhibitor, attenuates simple learning and memory deficits in ischemic rats. Brain Res. 2005, 1038:50-58.
5. Bradford M.M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
6. Conner J.M., Culberson A., Packowski C., Chiba A.A., Tuszynski M.H. Lesions of the Basal forebrain cholinergic system impair task acquisition and abolish cortical plasticity associated with motor skill learning. Neuron 2003, 38:819-829.
7. Cui Y., Yan Z., Hou S., Chang Z. Effect of radix Rehmanniae preparata on the expression of c-fos and NGF in hippocampi and learning and memory in mice with damaged thalamic arcuate nucleus. Zhong Yao Cai 2004, 27:589-592.
8. Ikonomovic M.D., Mufson E.J., Wuu J., Cochran E.J., Bennett D.A., DeKosky S.T. Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: correlation with Alzheimer's neuropathology. J. Alzheimers Dis. 2003, 5:39-48.
9. Ikonomovic M.D., Mufson E.J., Wuu J., Bennett D.A., DeKosky S.T. Reduction of choline acetyltransferase activity in primary visual cortex in mild to moderate Alzheimer's disease. Arch. Neurol. 2005, 62:425-430.
10. Li D.Q., Duan Y.L., Bao Y.M., Liu C.P., Liu Y., An L.J. Neuroprotection of catalpol in transient global ischemia in gerbils. Neurosci. Res. 2004, 50:169-177.
11. Liu J., He Q.J., Zou W., Wang H.X., Bao Y.M., Liu Y.X., An L.J. Catalpol increases hippocampal neuroplasticity and up-regulates PKC and BDNF in the aged rats. Brain Res. 2006, 1123:68-79.
12. Liu Y.Q., Xin T.R., Lü X.Y., Ji Q., Jin Y., Yang H.D. Memory performance of hypercholesterolemic mice in response to treatment with soy isoflavones. Neurosci. Res. 2007, 57:544-549.
13. Mao G.X., Deng H.B., Yuan L.G., Li D.D., Li Y.Y., Wang Z. Protective role of salidroside against aging in a mouse model induced by d-galactose. Biomed. Environ. Sci. 2010, 23:161-166.
14. Martinis M.De., Franceschi C., Monti D., Ginaldi L. Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity. FEBS Lett. 2005, 579:2035-2039.
15. Oda Y. Choline acetyltransferase: the structure, distribution and pathologic changes in the central nervous system. Pathol. Int. 1999, 49:921-937.
16. Reddy V.P., Beyaz A. Inhibitors of the Maillard reaction and AGE breakers as therapeutics for multiple diseases. Drug Discov. Today 2006, 11:646-654.
17. Roldán G., Bolanos-Badillo E., González-Sánchez H., Quirarte G.L., Prado-Alcalá R.A. Selective M1 muscarinic receptor antagonists disrupt memory consolidation of inhibitory avoidance in rats. Neurosci. Lett. 1997, 230:93-96.
18. Sawada M., Kondo N., Suzumura A., Marunouchi T. Production of tumor necrosis factor-alpha by microglia and astrocytes in culture. Brain Res. 1989, 491:394-397.
19. Semba R.D., Nicklett E.J., Ferrucci L. Does accumulation of advanced glycation end products contribute to the aging phenotype?. J. Gerontol. A Biol. Sci. Med. Sci. 2010, 65:963-975.
20. Song X., Bao M., Li D., Li Y.M. Advanced glycation in Dgalactose induced mouse aging model. Mech. Ageing Dev. 1999, 108:239-251.
21. Sonkusare S., Srinivasan K., Kaul C., Ramarao P. Effect of donepezil and lercanidipine on memory impairment induced by intracerebroventricular streptozotocin in rats. Life Sci. 2005, 77:1-14.
22. Terry A.V., Mahadik S.P. Time-dependent cognitive deficits associated with first and second generation antipsychotics: cholinergic dysregulation as a potential mechanism. J. Pharmacol. Exp. Ther. 2007, 320:961-968.
23. Tian J., Ishibashi K., Ishibashi K., Reiser K., Grebe R., Biswal S., Gehlbach P., Handa J.T. Advanced glycation endproduct-induced aging of the retinal pigment epithelium and choroid: a comprehensive transcriptional response. PNAS 2005, 102(33):11846-11851.
24. Tian Y.Y., An L.J., Jiang L., Duan Y.L., Chen J., Jiang B. Catalpol protects dopaminergic neurons from LPS-induced neurotoxicity in mesencephalic neuron-glia cultures. Life Sci. 2006, 80:193-199.
25. Tyagi E., Agrawal R., Nath C., Shukla R. Cholinergic protection via a7 nicotinic acetylcholine receptors and PI3K-Akt pathway in LPS-induced neuroinflammation. Neurochem. Int. 2010, 56:135-142.
26. Wei H.F., Li L., Song Q.J., Ai H.X., Chu J., Li W. Behavioural study of the d-galactose induced aging model in C57BL/6J mice. Neurochem. Int. 2005, 157:245-251.
27. Yu H., Oh-Hashi K., Tanaka T., Sai A., Inoue M., Hirata Y., Kiuchi K. Rehmannia glutinosa induces glial cell line-derived neurotrophic factor gene expression in astroglial cells via cPKC and ERK1/2 pathways independently. Pharmacol. Res. 2006, 54:39-45.
28. Zambrzycka A., Alberghina M., Strosznajder J.B. Effects of aging and amyloid-beta peptides on choline acetyltransferase activity in rat brain. Neurochem. Res. 2002, 27:277-281.
29. Zhang Q., Li X.K., Cui X., Zuo P.P. d-Galactose injured neurogenesis in the hippocampus of adult mice. Neurol. Res. 2005, 27:552-556.
30. Zhang X.L., Jiang B., Li Z.B., Hao S., An L.J. Catalpol ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by d-galactose. Pharmacol. Biochem. Behav. 2007, 88:64-72.
31. Zhang X.L., An L.J., Bao Y.M., Wang J.Y., Jiang B. d-galactose administration induces memory loss and energy metabolism disturbance in mice: protective effects of catalpol. Food Chem. Toxicol. 2008, 46:2888-2894.
32. Zhang X.L., Liu W.D., Niu X.H., An L.J. Systemic administration of catalpol prevents d-galactose induced mitochondrial dysfunction in mice. Neurosci. Lett. 2010, 473:224-228.