Chronic intermittent hypobaric hypoxia prevents cardiac dysfunction through enhancing antioxidation in fructose-fed rats

Canadian Journal of Physiology and Pharmacology

Volumn 91, Issue 5, 2013, Pages 332-337

  Zhou, Jing Jing ^a   Wei, Yan ^a   Zhang, Li ^a   Zhang, Jiao ^a   Guo, Lan Ying ^a   Gao, Chao ^a   Li, De Pei ^b   Zhang, Yi ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Antioxidation; Cardioprotection; Chronic intermittent hypobaric hypoxia; Metabolic syndrome

Indexed keywords

C PEPTIDE; CATALASE; CHOLESTEROL; COPPER ZINC SUPEROXIDE DISMUTASE; DRINKING WATER; FRUCTOSE; GLUCOSE; INSULIN; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL;

ALTITUDE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE; CARDIOVASCULAR PROCEDURE; CHOLESTEROL BLOOD LEVEL; CHRONIC INTERMITTENT HYPOBARIC HYPOXIA; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HEART DISEASE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; HEART VOLUME; HYPOBARISM; INSULIN BLOOD LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMAL FEED; ANIMALS; ANOXIA; ANTIOXIDANTS; BLOOD GLUCOSE; BLOOD PRESSURE; C-PEPTIDE; CHOLESTEROL; FRUCTOSE; HEART; INSULIN; MALE; MALONDIALDEHYDE; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SUPEROXIDE DISMUTASE; TRIGLYCERIDES; VENTRICULAR FUNCTION, LEFT;

EID: 84877342526     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/cjpp-2012-0059     Document Type: Article

References (28)

1. Aiello, E.A., Villa-Abrille, M.C., Escudero, E.M., Portiansky, E.L., Perez, N.G., de Hurtado, M.C., and Cingolani, H.E. 2004. Myocardial hypertrophy of normotensive Wistar-Kyoto rats. Am. J. Physiol. Heart Circ. Physiol. 286(4): H1229-H1235. doi:10.1152/ajpheart.00779.2003. PMID:14630632.
2. Beckman, J.A., Creager, M.A., and Libby, P. 2002. Diabetes and atherosclerosis epidemiology, pathophysiology, and management. JAMA, 287: 2570-2581. doi:10.1001/jama.287.19.2570. PMID:12020339.
3. Belfort, R., Mandarino, L., Kashyap, S., Wirfel, K., Pratipanawatr, T., Berria, R., et al. 2005. Dose-response effect of elevated plasma free fatty acid on insulin signaling. Diabetes, 54: 1640-1648. doi:10.2337/diabetes.54.6.1640. PMID: 15919784.
4. Deng, J.Y., Huang, J.P., Lu, L.S., and Hung, L.M. 2007. Impairment of cardiac insulin signaling and C myocardial contractile performance in highcholesterol/ fructose-fed rats. Am. J. Physiol. Heart Circ. Physiol. 293: H978-H987. doi:10.1152/ajpheart.01002.2006. PMID:17400720.
5. Faure, P., Rossini, E., Wiernsperger, N., Richard, M.J., Favier, A., and Halimi, S. 1999. An insulin sensitizer improves the free radical defense system potential and insulin sensitivity in high fructose-fed rats. Diabetes, 48(2): 353-357. doi:10.2337/diabetes.48.2.353. PMID:10334313.
6. Ferrannini, E., Haffner, S.M., Mitchell, B.D., and Stern, M.P. 1991. Hyperinsulinemia: the key feature of a cardiovascular and metabolic syndrome. Diabetologia, 34: 416-422. doi:10.1007/BF00403180. PMID:1884900.
7. Gao, J.P., Chen, C.X., Wang, Y., Lü, J., and Gu, W.L. 2009. Effect of sodium houttuyfonate on myocardial hypertrophy in mice and rats. J. Pharm. Pharmacol. 61(5): 677-683. doi:10.1211/jpp.61.05.0018. PMID:19406008.
8. Giani, J.F., Mayer, M.A., Munoz, M.C., Silberman, E.A., Hocht, C., Taira, C.A, et al. 2009. Chronic infusion of angiotensin-(1-7) improves insulin resistance and hypertension induced by a high-fructose diet in rats. Am. J. Physiol. Endocrinol. Metab. 296(2): E262-E271. doi:10.1152/ajpendo.90678.2008. PMID:19001546.
9. Guan, Y., Gao, L., Ma, H.J., Li, Q., Zhang, H., Yuan, F., et al. 2010. Chronic intermittent hypobaric hypoxia decreases β-adrenoceptor activity in right ventricular papillary muscle. Am. J. Physiol. Heart Circ. Physiol. 298(4): H1267-H1272. doi:10.1152/ajpheart.00410.2009. PMID:20097768.
10. Guo, H.C., Zhang, Z., Zhang, L.N., Xiong, C., Feng, C., Liu, Q., et al. 2009. Chronic intermittent hypobaric hypoxia protects the heart against ischemia/reperfusion injury through upregulation of antioxidant enzymes in adult guinea pigs. Acta Pharmacol. Sin. 30(7): 947-955. doi:10.1038/aps.2009.57. PMID: 19543301.
11. Larsen, J.J., Hansen, J.M., Olsen, N.V., Galbo, H., and Dela, F. 1997. The effect of altitude hypoxia on glucose homeostasis in men. J. Physiol. 504(1): 241-249. doi:10.1111/j.1469-7793.1997.241bf.x. PMID:9350634.
12. Marfella, R., D'Amico, M., Di Filippo, C., Piegari, E., Nappo, F., Esposito, K., et al. 2002. Myocardial infarction in diabetic rats: role of hyperglycaemia on infarct size and early expression of hypoxia-inducible factor 1. Diabetologia, 45(8): 1172-1181. doi:10.1007/s00125-002-0882-x. PMID:12189448.
13. Mir, S.A., Chatterjee, A., Mitra, A., Pathak, K., Mahata, S.K., and Sarkar, S. 2012. Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced collagen synthesis and resultant hypertrophy in rat heart. J. Biol. Chem. 287(4): 2666-2677. doi:10.1074/jbc.M111.246173. PMID:22157761.
14. Nandhini, A.T., Thirunavukkarasu, V., Ravichandran, M.K., and Anuradha, C.V. 2005. Effect of taurine on biomarkers of oxidative stress in tissues of fructosefed insulin-resistant rats. Singapore Med. J. 46: 82-87. PMID:15678290.
15. National Research Council. 2006. Guide for the care and use of laboratory animals. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Academy Press, Washington, D.C.
16. Novelletto, B.F., Guzzinati, S., and Avogaro, A. 2012. Prevalence of metabolic syndrome and its relationship with clinically prevalent cardiovascular disease in the Veneto region, northeastern Italy. Metab. Syndr. Relat. Disord. 10(1): 56-62. doi:10.1089/met.2011.0065. PMID:22004284.
17. Pillutla, P., Hwang, Y.C., Augustus, A., Yokoyama, M., Yagyu, H., Johnston, T.P., et al. 2005. Perfusion of hearts with triglyceride-rich particles reproduces the metabolic abnormalities in lipotoxic cardiomyopathy. Am. J. Physiol. Endocrinol. Metab. 288: E1229-E1235. doi:10.1152/ajpendo.00273.2004. PMID: 15701679.
18. Reaven, G.M. 1988. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes, 37(12): 1595-1607. doi:10.2337/diabetes.37.12.1595. PMID: 3056758.
19. Schobersberger, W., Leichtfried, V., Mueck-Weymann, M., and Humpeler, E. 2010 Austrian Moderate Altitude Studies (AMAS): benefits of exposure to moderate altitudes (1,500-2,500 m). Sleep Breath, 14(3): 201-207. doi:10.1007/s11325-009-0286-y. PMID:19669819.
20. Slezak, J., Tribulova, N., Pristacova, J., Uhrik, B., Thomas, T., Khaper, N., et al. 1995. Hydrogen peroxide changes in ischemic and reperfused heart. Cytochemistry and biochemical and X-ray microanalysis. Am. J. Pathol. 147(3): 772-781. PMID:7677188.
21. Stepniakowski, K.T., Goodfriend, T.L., and Egan, B.M. 1995. Fatty acids enhance vascular α-adrenergic sensitivity. Hypertension, 25: 774-778. doi:10.1161/01.HYP.25.4.774. PMID:7721431.
22. Thirunavukkarasu, V., Anitha Nandhini, A.T., and Anuradha, C.V. 2004. Cardiac lipids and antioxidant status in high fructose rats and the effect of α-lipoic acid. Nutr. Metab. Cardiovasc. Dis. 14: 351-357. doi:10.1016/S0939-4753(04)80025-5. PMID:15853119.
23. van Eickels, M., Schreckenberg, R., Doevendans, P.A., Meyer, R., Grohe, C., and Schluter, K.D. 2005. The influence of oestrogen-deficiency and ACE inhibition on the progression of myocardial hypertrophy in spontaneously hypertensive rats. Eur. J. Heart Fail. 7(7): 1079-1084. doi:10.1016/j.ejheart.2005.03.004. PMID:15922661.
24. Zhang, Y., Zhong, N., Zhu, H.F., and Zhou, Z.N. 2000. Antiarrhythmic and antioxidative effects of intermittent hypoxia exposure on rat myocardium. Sheng Li Xue Bao, 52(2): 89-92. PMID:11961574.
25. Zhang, Y., Zhong, N., Gia, J., and Zhou, Z. 2004. Effects of chronic intermittent hypoxia on the hemodynamics of systemic circulation in rats. Jpn. J. Physiol. 54(2): 171-174. doi:10.2170/jjphysiol.54.171. PMID:15182424.
26. Zhang, Y., Yang, H.T., and Zhou, Z.N. 2007. The cardioprotection of intermittent hypoxic adaptation. Sheng Li Xue Bao, 59(5): 601-613. PMID:17940700.
27. Zhong, M., Tan, H.W., Gong, H.P., Wang, S.F., Zhang, Y., and Zhang, W. 2008. Increased serum visfatin in patients with metabolic syndrome and carotid atherosclerosis. Clin. Endocrinol. (Oxf.), 69(6): 878-884. doi:10.1111/j.1365-2265.2008.03248.x.
28. Zhong, N., Zhang, Y., Zhu, H.F., Wang, J.C., Fang, Q.Z., and Zhou, Z.N. 2002. Myocardial capillary angiogenesis and coronary flow in ischemia tolerance rat by adaptation to intermittent high altitude hypoxia. Acta Pharmacol. Sin. 23(4): 305-310. PMID:11931703.