Davallialactone protects against acetaminophen overdose-induced liver injuries in mice

Food and Chemical Toxicology

Volumn 58, Issue , 2013, Pages 14-21

  Noh, Jung Ran ^a   Kim, Yong Hoon ^a   Hwang, Jung Hwan ^a   Gang, Gil Tae ^a   Kim, Kyoung Shim ^a   Lee, In Kyoung ^b   Yun, Bong Sik ^b   Lee, Chul Ho ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chonbuk National University   (South Korea)

Author keywords

Acetaminophen; Davallialactone; Liver; Oxidative stress; Toxicity

Indexed keywords

3 NITROTYROSINE; ADENOSINE TRIPHOSPHATE; ALANINE AMINOTRANSFERASE; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; DAVALLIALACTONE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GUANOSINE TRIPHOSPHATE; LIVER PROTECTIVE AGENT; MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE; PARACETAMOL; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DISEASE SEVERITY; DRUG SCREENING; ENZYME ACTIVATION; ENZYME REPRESSION; LIPID PEROXIDATION; LIVER INJURY; LIVER NECROSIS; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; SURVIVAL RATE; TREATMENT OUTCOME;

ACETAMINOPHEN; DAVALLIALACTONE; LIVER; OXIDATIVE STRESS; TOXICITY;

ACETAMINOPHEN; ADENOSINE TRIPHOSPHATE; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; DRUG OVERDOSE; DRUG-INDUCED LIVER INJURY; GLUTATHIONE; LACTONES; MALE; MICE; MICE, INBRED BALB C; SURVIVAL RATE;

EID: 84877329402     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.04.005     Document Type: Article

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