Akt2 influences glycogen synthase activity in human skeletal muscle through regulation of NH2-terminal (sites 2 + 2a) phosphorylation

American Journal of Physiology - Endocrinology and Metabolism

Volumn 304, Issue 6, 2013, Pages

  Friedrichsen, Martin ^a,b,c   Birk, Jesper B ^c   Richter, Erik A ^c   Ribel Madsen, Rasmus ^a   Pehmøller, Christian ^c,d   Hansen, Bo Falck ^e   Beck Nielsen, Henning ^f   Hirshman, Michael F ^d   Goodyear, Laurie J ^d   Vaag, Allan ^a,g   Poulsen, Pernille ^a,e   Wojtaszewski, Jørgen F P ^c  

^a STENO DIABETES CENTER   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d HARVARD MEDICAL SCHOOL   (United States)

^e NOVO NORDISK A S   (Denmark)

^f ODENSE UNIVERSITY HOSPITAL   (Denmark)

^g Rigshospitalet   (Denmark)

Author keywords

Diabetes; Glycogen synthesis; Insulin signaling; Muscle; Phosphatidylinositol 3 kinase protein kinase B

Indexed keywords

INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B BETA; AKT2 PROTEIN, HUMAN; AKT2 PROTEIN, MOUSE; GLYCOGEN SYNTHASE; INSULIN; PROTEIN KINASE B; THREONINE;

ADULT; AGED; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN TISSUE; MALE; MONOZYGOTIC TWINS; MOUSE; MUSCLE BIOPSY; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; WESTERN BLOTTING; ANIMAL; BLOOD; C57BL MOUSE; COHORT ANALYSIS; CROSS-SECTIONAL STUDY; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; METABOLISM; MIDDLE AGED; MOUSE MUTANT; PHOSPHORYLATION; PROTEIN PROCESSING; TWINS;

ADULT; AGED; ANIMALS; COHORT STUDIES; CROSS-SECTIONAL STUDIES; ENZYME ACTIVATION; FEMALE; GLYCOGEN SYNTHASE; HUMANS; INSULIN; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; MUSCLE, SKELETAL; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; THREONINE; YOUNG ADULT;

MLCS; MLOWN;

EID: 84877305521     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00494.2012     Document Type: Article

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