Therapeutic mild hypothermia: Effects on coagulopathy and survival in a rat hemorrhagic shock model

Journal of Trauma - Injury, Infection and Critical Care

Volumn 68, Issue 3, 2010, Pages 669-675

  Iwamoto, Shinichiro ^a   Takasu, Akira ^a   Sakamoto, Toshihisa ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

Coagulopathy; Hemorrhagic shock; Hypothermia; Outcome

Indexed keywords

ALPHA 2 ANTIPLASMIN; RINGER SOLUTION; THROMBIN ANTITHROMBIN COMPLEX;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOTTING DISORDER; DISEASE MODEL; FIBRINOLYSIS; FLUID RESUSCITATION; HEMATOCRIT; HEMODYNAMICS; HEMORRHAGIC SHOCK; HYPOTHERMIA; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; RECTUM TEMPERATURE; SURVIVAL RATE;

ANIMALS; BLOOD COAGULATION; BLOOD COAGULATION FACTORS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; FLUID THERAPY; HYPOTHERMIA, INDUCED; MALE; RATS; RATS, SPRAGUE-DAWLEY; SERPINS; SHOCK, HEMORRHAGIC; SURVIVAL ANALYSIS;

EID: 77949470721     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e3181a0fbb3     Document Type: Article

References (19)

1. Takasu A, Carrillo P, Stezoski W, et al. Mild or moderate hypothermia but not increased oxygen breathing prolongs survival during lethal uncontrolled hemorrhagic shock in rats, with monitoring of visceral dysoxia. Crit Care Med. 1999;27:1557-1564.
2. Takasu A, Stezoski W, Stezoski J, et al. Mild or moderate hypothermia, but not increases oxygen breathing, increases long-term survival after uncontrolled hemorrhagic shock in rats. Crit Care Med. 2000;28:2465-2474.
3. Takasu A, Norio H, Sakamoto T, Okada Y. Mild hypothermia prolongs the survival time during uncontrolled hemorrhagic shock in rats. Resuscitation. 2002;54:303-309.
4. Luna GK, Maier RV, Pavlin EG, Anardi D, Copass MK, Oreskovich MR. Incidence and effect of hypothermia in seriously injured patients. J Trauma. 1987;27:1014-1018.
5. Jurkovich GJ, Greiser WB, Luteman A, Curreri PW. Hypothermia in trauma victims: an ominous predictor of survival. J Trauma. 1987;27: 1019-1024.
6. Cosgriff N, Moore EE, Sauaia A, Kenny-Moynihan M, Burch JM, Galloway B. Predicting life-threatening coaogulopathy in the massively transfused trauma patient: hypothermia and acidoses revisited. J Trauma. 1997;42:857-861.
7. Watts DD, Trask A, Soeken K, Perdue P, Dols S, Kaufmann C. Hypothermic coagulopathy in trauma: effect of varying levels of hypothermia on enzyme speed, platelet function, and fibrinolytic activity. J Trauma. 1998;44:846-854.
8. Stern SA, Dronen SC, Birrer P, Wang X. Effect of blood pressure on hemorrhage volume and survival in a near-fatal hemorrhage model incorporating a vascular injury. Ann Emerg Med. 1993;22:155-163.
9. Takaksu A, Yanagawa Y, Sakamoto T, et al. Therapeutic hypothermia limited to the resuscitation period does not prolong survival after severe hemorrhagic shock in rats. Resuscitation. 2005;67:119-126.
10. Capone A, Safar P, Stezoski SW, Peitzman A, Tisherman S. Uncontrolled hemorrhagic shock outcome model in rats. Resuscitation. 1995; 29:143-152.
11. Anaya-Prado R, Toledo-Pereya LH, Walsh J, Guo RF, Reuben J, Ward PA. Exogenous nitric oxide donor and related compounds protect against lung inflammatory response after hemorrhagic shock and resuscitation. J Trauma. 2004;57:980-988.
12. Britt L, Dascombe W, Rodriguez A. New horizons in management of hypothermia and frostbite injury. Surg Clin North Am. 1991;71:345-370.
13. Wu X, Kochanek PM, Cochran K, et al. Mild hypothermia improves survival after prolonged, traumatic hemorrhagic shock in pigs. J Trauma. 2005;59:291-299.
14. Brohi K, Singh J, Heron M, et al. Acute traumatic coagulopathy. J Trauma. 2003;54:1127-1130.
15. Gubler KD, Gentilello LM, Hassantash SA, Maier RV. The impact of hypothermia on dilutional coagulopathy. J Trauma. 1994;36:847-850.
16. Prueckner S, Safar P, Kentner R, Stezoski J, Tisherman SA. Mild hypothermia increases survival from severe pressure-controlled hemorrhagic shock in rats. J Trauma. 2001;50:253-262.
17. Wu X, Stezoski J, Safar P, et al. Systemic hypothermia, but not regional gut hypothermia, improves survival from prolonged hemorrhagic shock in rats. J Trauma. 2002;53:654-662.
18. Meyer DM, Horton JW. Effect of moderate hypothermia in the treatment of canine hemorrhagic shock. Ann Surg. 1988;207:462-469.
19. Meyer DM, Horton JW. Effect of different degrees of hypothermia on myocardium treatment of hemorrhagic shock. J Surg Res. 1990;48: 61-97.