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Volumn 22, Issue 3, 2013, Pages 393-412

Human mesenchymal precursor cells (Stro-1+) from spinal cord injury patients improve functional recovery and tissue sparing in an acute spinal cord injury rat model

Author keywords

Cellular therapy; Contusion; Mesenchymal precursors; Spinal cord (SC); Transplantation

Indexed keywords

BETA TUBULIN; CELL NUCLEUS ANTIGEN; CYCLOSPORIN A; FIBRONECTIN; LAMININ;

EID: 84877267545     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368912X656081     Document Type: Article
Times cited : (36)

References (85)
  • 1
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal, S.; Pittenger, M. F. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 105(4):1815-1822; 2005.
    • (2005) Blood , vol.105 , Issue.4 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 2
    • 0036703491 scopus 로고    scopus 로고
    • Remyelination of the rat spinal cord by transplantation of identified bone marrow stromal cells
    • Akiyama, Y.; Radtke, C.; Kocsis, J. D. Remyelination of the rat spinal cord by transplantation of identified bone marrow stromal cells. J. Neurosci. 22(15):6623-6630; 2002.
    • (2002) J. Neurosci. , vol.22 , Issue.15 , pp. 6623-6630
    • Akiyama, Y.1    Radtke, C.2    Kocsis, J.D.3
  • 3
    • 0032584132 scopus 로고    scopus 로고
    • Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats-similarities to astrocyte grafts
    • Azizi, S. A.; Stokes, D.; Augelli, B. J.; DiGirolamo, C.; Prockop, D. J. Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats-similarities to astrocyte grafts. Proc. Natl. Acad. Sci. USA 95(7):3908-3913; 1998.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , Issue.7 , pp. 3908-3913
    • Azizi, S.A.1    Stokes, D.2    Augelli, B.J.3    DiGirolamo, C.4    Prockop, D.J.5
  • 4
    • 0036454402 scopus 로고    scopus 로고
    • A review of the adaptability and recovery of locomotion after spinal cord injury
    • Barbeau, H.; Fung, J.; Leroux, A.; Ladouceur, M. A review of the adaptability and recovery of locomotion after spinal cord injury. Prog. Brain Res. 137:9-25; 2002.
    • (2002) Prog. Brain Res. , vol.137 , pp. 9-25
    • Barbeau, H.1    Fung, J.2    Leroux, A.3    Ladouceur, M.4
  • 6
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • Basso, D. M.; Beattie, M. S.; Bresnahan, J. C. A sensitive and reliable locomotor rating scale for open field testing in rats. J. Neurotrauma 12(1):1-21; 1995.
    • (1995) J. Neurotrauma , vol.12 , Issue.1 , pp. 1-21
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 7
    • 0034254209 scopus 로고    scopus 로고
    • Transplanted glial cells migrate over a greater distance and remyelinate demyelinated lesions more rapidly than endogenous remyelinating cells
    • Blakemore, W. F.; Gilson, J. M.; Crang, A. J. Transplanted glial cells migrate over a greater distance and remyelinate demyelinated lesions more rapidly than endogenous remyelinating cells. J. Neurosci. Res. 61(3):288-294; 2000.
    • (2000) J. Neurosci. Res. , vol.61 , Issue.3 , pp. 288-294
    • Blakemore, W.F.1    Gilson, J.M.2    Crang, A.J.3
  • 8
    • 0242497104 scopus 로고    scopus 로고
    • Cellular GDNF delivery promotes growth of motor and dorsal column sensory axons after partial and complete spinal cord transections and induces remyelination
    • Blesch, A.; Tuszynski, M. H. Cellular GDNF delivery promotes growth of motor and dorsal column sensory axons after partial and complete spinal cord transections and induces remyelination. J. Comp. Neurol. 467(3):403-417; 2003.
    • (2003) J. Comp. Neurol. , vol.467 , Issue.3 , pp. 403-417
    • Blesch, A.1    Tuszynski, M.H.2
  • 9
    • 5644264890 scopus 로고    scopus 로고
    • Axonal responses to cellularly delivered NT-4/5 after spinal cord injury
    • Blesch, A.; Yang, H.; Weidner, N.; Hoang, A.; Otero, D. Axonal responses to cellularly delivered NT-4/5 after spinal cord injury. Mol. Cell. Neurosci. 27(2):190-201; 2004.
    • (2004) Mol. Cell. Neurosci. , vol.27 , Issue.2 , pp. 190-201
    • Blesch, A.1    Yang, H.2    Weidner, N.3    Hoang, A.4    Otero, D.5
  • 11
    • 50849122983 scopus 로고    scopus 로고
    • All MSCs are pericytes
    • Caplan, A. I. All MSCs are pericytes? Cell Stem Cell 3(3):229-230; 2008.
    • (2008) Cell Stem Cell , vol.3 , Issue.3 , pp. 229-230
    • Caplan, A.I.1
  • 12
    • 0021016020 scopus 로고
    • Antibody-dependent cellular cytotoxicity and natural killing in nude rats: Quantitative study according to age and sex
    • Chassoux, D.; Dokhelar, M. C.; Tursz, T.; Salomon, J. C. Antibody-dependent cellular cytotoxicity and natural killing in nude rats: Quantitative study according to age and sex. Ann. Immunol. 134D(3):309-318; 1983.
    • (1983) Ann. Immunol. , vol.134 , Issue.3 , pp. 309-318
    • Chassoux, D.1    Dokhelar, M.C.2    Tursz, T.3    Salomon, J.C.4
  • 13
    • 38749109267 scopus 로고    scopus 로고
    • Stem cells for the treatment of spinal cord injury
    • Coutts, M.; Keirstead, H. S. Stem cells for the treatment of spinal cord injury. Exp. Neurol. 209(2):368-377; 2008.
    • (2008) Exp. Neurol. , vol.209 , Issue.2 , pp. 368-377
    • Coutts, M.1    Keirstead, H.S.2
  • 15
    • 34247881862 scopus 로고    scopus 로고
    • Strain-specific differences in the effects of cyclosporin A and FK506 on the survival and regeneration of axotomized retinal ganglion cells in adult rats
    • Cui, Q.; Hodgetts, S. I.; Hu, Y.; Luo, J. M.; Harvey, A. R. Strain-specific differences in the effects of cyclosporin A and FK506 on the survival and regeneration of axotomized retinal ganglion cells in adult rats. Neuroscience 146(3):986-999; 2007.
    • (2007) Neuroscience , vol.146 , Issue.3 , pp. 986-999
    • Cui, Q.1    Hodgetts, S.I.2    Hu, Y.3    Luo, J.M.4    Harvey, A.R.5
  • 16
    • 0036244446 scopus 로고    scopus 로고
    • Origin and differentiation of human and murine stroma
    • Dennis, J. E.; Charbord, P. Origin and differentiation of human and murine stroma. Stem Cells 20(3):205-214; 2002.
    • (2002) Stem Cells , vol.20 , Issue.3 , pp. 205-214
    • Dennis, J.E.1    Charbord, P.2
  • 18
    • 33646761987 scopus 로고    scopus 로고
    • Transplantation of Schwann cells to subarachnoid space induces repair in contused rat spinal cord
    • Firouzi, M.; Moshayedi, P.; Saberi, H.; Mobasheri, H.; Abolhassani, F.; Jahanzad, I.; Raza, M. Transplantation of Schwann cells to subarachnoid space induces repair in contused rat spinal cord. Neurosci. Lett. 402(1-2):66-70; 2006.
    • (2006) Neurosci. Lett. , vol.402 , Issue.1-2 , pp. 66-70
    • Firouzi, M.1    Moshayedi, P.2    Saberi, H.3    Mobasheri, H.4    Abolhassani, F.5    Jahanzad, I.6    Raza, M.7
  • 20
    • 16944366150 scopus 로고    scopus 로고
    • Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury
    • Grill, R.; Murai, K.; Blesch, A.; Gage, F. H.; Tuszynski, M. H. Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. J. Neurosci. 17(14):5560-5572; 1997.
    • (1997) J. Neurosci. , vol.17 , Issue.14 , pp. 5560-5572
    • Grill, R.1    Murai, K.2    Blesch, A.3    Gage, F.H.4    Tuszynski, M.H.5
  • 21
    • 0028102611 scopus 로고
    • The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursors
    • Gronthos, S.; Graves, S. E.; Ohta, S.; Simmons, P. J. The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursors. Blood 84(12):4164-4173; 1994.
    • (1994) Blood , vol.84 , Issue.12 , pp. 4164-4173
    • Gronthos, S.1    Graves, S.E.2    Ohta, S.3    Simmons, P.J.4
  • 22
    • 0029767708 scopus 로고    scopus 로고
    • The biology and application of human bone marrow stromal cell precursors
    • Gronthos, S.; Simmons, P. J. The biology and application of human bone marrow stromal cell precursors. J. Hemathother. 5(1):15-23; 1996.
    • (1996) J. Hemathother. , vol.5 , Issue.1 , pp. 15-23
    • Gronthos, S.1    Simmons, P.J.2
  • 23
    • 0035137944 scopus 로고    scopus 로고
    • Integrin-mediated interactions between human bone marrow stromal precursor cells and the extracellular matrix
    • Gronthos, S.; Simmons, P. J.; Graves, S. E.; Robey, P. G. Integrin-mediated interactions between human bone marrow stromal precursor cells and the extracellular matrix. Bone 28(2):174-181; 2001.
    • (2001) Bone , vol.28 , Issue.2 , pp. 174-181
    • Gronthos, S.1    Simmons, P.J.2    Graves, S.E.3    Robey, P.G.4
  • 24
    • 0038664242 scopus 로고    scopus 로고
    • Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow
    • Gronthos, S.; Zannettino, A. C.; Hay, S. J.; Shi, S.; Graves, S. E.; Kortesidis, A.; Simmons, P. J. Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow. J. Cell Sci. 116(Pt 9): 1827-1835; 2003.
    • (2003) J. Cell Sci. , vol.116 , Issue.PART 9 , pp. 1827-1835
    • Gronthos, S.1    Zannettino, A.C.2    Hay, S.J.3    Shi, S.4    Graves, S.E.5    Kortesidis, A.6    Simmons, P.J.7
  • 25
    • 33646577436 scopus 로고    scopus 로고
    • Degenerative and spontaneous regenerative processes after spinal cord injury
    • Hagg, T.; Oudega, M. Degenerative and spontaneous regenerative processes after spinal cord injury. J. Neurotrauma 23(3-4):263-280; 2006.
    • (2006) J. Neurotrauma , vol.23 , Issue.3-4 , pp. 263-280
    • Hagg, T.1    Oudega, M.2
  • 26
    • 28244488983 scopus 로고    scopus 로고
    • Immunosuppression with either cyclosporine a or FK506 supports survival of transplanted fibroblasts and promotes growth of host axons into the transplant after spinal cord injury
    • Hayashi, Y.; Shumsky, J. S.; Connors, T.; Otsuka, T.; Fischer, I.; Tessler, A.; Murray, M. Immunosuppression with either cyclosporine a or FK506 supports survival of transplanted fibroblasts and promotes growth of host axons into the transplant after spinal cord injury. J. Neurotrauma 22(11):1267-1281; 2005.
    • (2005) J. Neurotrauma , vol.22 , Issue.11 , pp. 1267-1281
    • Hayashi, Y.1    Shumsky, J.S.2    Connors, T.3    Otsuka, T.4    Fischer, I.5    Tessler, A.6    Murray, M.7
  • 27
    • 33744914853 scopus 로고    scopus 로고
    • Comparative analysis of neuroectodermal differentiation capacity of human bone marrow stromal cells using various conversion protocols
    • Hermann, A.; Liebau, S.; Gastl, R.; Fickert, S.; Habisch, H. J.; Fiedler, J.; Schwarz, J.; Brenner, R.; Storch, A. Comparative analysis of neuroectodermal differentiation capacity of human bone marrow stromal cells using various conversion protocols. J. Neurosci. Res. 83(8):1502-1514; 2006.
    • (2006) J. Neurosci. Res. , vol.83 , Issue.8 , pp. 1502-1514
    • Hermann, A.1    Liebau, S.2    Gastl, R.3    Fickert, S.4    Habisch, H.J.5    Fiedler, J.6    Schwarz, J.7    Brenner, R.8    Storch, A.9
  • 28
    • 33746055381 scopus 로고    scopus 로고
    • Epigenetic conversion of human adult bone mesodermal stromal cells into neuroectodermal cell types for replacement therapy of neurodegenerative disorders
    • Hermann, A.; Maisel, M.; Storch, A. Epigenetic conversion of human adult bone mesodermal stromal cells into neuroectodermal cell types for replacement therapy of neurodegenerative disorders. Expert Opin. Biol. Ther. 6(7):653-670; 2006.
    • (2006) Expert Opin. Biol. Ther. , vol.6 , Issue.7 , pp. 653-670
    • Hermann, A.1    Maisel, M.2    Storch, A.3
  • 30
    • 0344687376 scopus 로고    scopus 로고
    • A role for natural killer cells in the rapid death of cultured donor myoblasts after transplantation
    • Hodgetts, S. I.; Spencer, M. J.; Grounds, M. D. A role for natural killer cells in the rapid death of cultured donor myoblasts after transplantation. Transplantation 75(6):863-871; 2003.
    • (2003) Transplantation , vol.75 , Issue.6 , pp. 863-871
    • Hodgetts, S.I.1    Spencer, M.J.2    Grounds, M.D.3
  • 32
    • 33646346844 scopus 로고    scopus 로고
    • Tissue-engineered peripheral nerve grafting by differentiated bone marrow stromal cells
    • Hou, S. Y.; Zhang, H. Y.; Quan, D. P.; Liu, X. L.; Zhu, J. K. Tissue-engineered peripheral nerve grafting by differentiated bone marrow stromal cells. Neuroscience 140(1):101-110; 2006.
    • (2006) Neuroscience , vol.140 , Issue.1 , pp. 101-110
    • Hou, S.Y.1    Zhang, H.Y.2    Quan, D.P.3    Liu, X.L.4    Zhu, J.K.5
  • 33
    • 0038722051 scopus 로고    scopus 로고
    • Effects of cyclosporin-A on immune response, tissue protection and motor function of rats subjected to spinal cord injury
    • Ibarra, A.; Correa, D.; Willms, K.; Merchant, M. T.; Guizar-Sahagun, G.; Grijalva, I.; Madrazo, I. Effects of cyclosporin-A on immune response, tissue protection and motor function of rats subjected to spinal cord injury. Brain Res. 979(1-2):165-178; 2003.
    • (2003) Brain Res. , vol.979 , Issue.1-2 , pp. 165-178
    • Ibarra, A.1    Correa, D.2    Willms, K.3    Merchant, M.T.4    Guizar-Sahagun, G.5    Grijalva, I.6    Madrazo, I.7
  • 35
    • 0032212449 scopus 로고    scopus 로고
    • Brainderived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury
    • Jakeman, L. B.; Wei, P.; Guan, Z.; Stokes, B. T. Brainderived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury. Exp. Neurol. 154(1):170-184; 1998.
    • (1998) Exp. Neurol. , vol.154 , Issue.1 , pp. 170-184
    • Jakeman, L.B.1    Wei, P.2    Guan, Z.3    Stokes, B.T.4
  • 36
    • 0142250844 scopus 로고    scopus 로고
    • Axonal regeneration through regions of chondroitin sulfate proteoglycan deposition after spinal cord injury: A balance of permissiveness and inhibition
    • Jones, L. L.; Sajed, D.; Tuszynski, M. H. Axonal regeneration through regions of chondroitin sulfate proteoglycan deposition after spinal cord injury: A balance of permissiveness and inhibition. J. Neurosci. 23(28):9276-9288; 2003.
    • (2003) J. Neurosci. , vol.23 , Issue.28 , pp. 9276-9288
    • Jones, L.L.1    Sajed, D.2    Tuszynski, M.H.3
  • 37
    • 1942425470 scopus 로고    scopus 로고
    • Neural precursors as a cell source to repair the demyelinated spinal cord
    • Kocsis, J. D.; Akiyama, Y.; Radtke, C. Neural precursors as a cell source to repair the demyelinated spinal cord. J. Neurotrauma 21(4):441-449; 2004.
    • (2004) J. Neurotrauma , vol.21 , Issue.4 , pp. 441-449
    • Kocsis, J.D.1    Akiyama, Y.2    Radtke, C.3
  • 38
    • 0032874061 scopus 로고    scopus 로고
    • Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
    • Kopen, G. C.; Prockop, D. J.; Phinney, D. G. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc. Natl. Acad. Sci. USA 96(19):10711-10716; 1999.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , Issue.19 , pp. 10711-10716
    • Kopen, G.C.1    Prockop, D.J.2    Phinney, D.G.3
  • 39
    • 33646043770 scopus 로고    scopus 로고
    • Adult rat bone marrow stromal cells express genes associated with dopamine neurons
    • Kramer, B. C.; Woodbury, D.; Black, I. B. Adult rat bone marrow stromal cells express genes associated with dopamine neurons. Biochem. Biophys. Res. Commun. 343(4):1045-1052; 2006.
    • (2006) Biochem. Biophys. Res. Commun. , vol.343 , Issue.4 , pp. 1045-1052
    • Kramer, B.C.1    Woodbury, D.2    Black, I.B.3
  • 40
    • 0037121743 scopus 로고    scopus 로고
    • Delivery of hyper-interleukin-6 to the injured spinal cord increases neutrophil and macrophage infiltration and inhibits axonal growth
    • Lacroix, S.; Chang, L.; Rose-John, S.; Tuszynski, M. H. Delivery of hyper-interleukin-6 to the injured spinal cord increases neutrophil and macrophage infiltration and inhibits axonal growth. J. Comp. Neurol. 454(3):213-228; 2002.
    • (2002) J. Comp. Neurol. , vol.454 , Issue.3 , pp. 213-228
    • Lacroix, S.1    Chang, L.2    Rose-John, S.3    Tuszynski, M.H.4
  • 41
    • 80053407028 scopus 로고    scopus 로고
    • Tissue Distribution of Mesenchymal Stem Cell Marker Stro-1
    • Lin, G.; Liu, G.; Banie, L.; Wang, G.; Ning, H.; Lue, T. F.; Lin, C. S. Tissue Distribution of Mesenchymal Stem Cell Marker Stro-1. Stem Cells Dev. 20(10):1747-1752; 2011.
    • (2011) Stem Cells Dev. , vol.20 , Issue.10 , pp. 1747-1752
    • Lin, G.1    Liu, G.2    Banie, L.3    Wang, G.4    Ning, H.5    Lue, T.F.6    Lin, C.S.7
  • 42
    • 0033151593 scopus 로고    scopus 로고
    • Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function
    • Liu, Y.; Kim, D.; Himes, B. T.; Chow, S. Y.; Schallert, T.; Murray, M.; Tessler, A.; Fischer, I. Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function. J. Neurosci. 19(11):4370-4387; 1999.
    • (1999) J. Neurosci. , vol.19 , Issue.11 , pp. 4370-4387
    • Liu, Y.1    Kim, D.2    Himes, B.T.3    Chow, S.Y.4    Schallert, T.5    Murray, M.6    Tessler, A.7    Fischer, I.8
  • 43
    • 51349141776 scopus 로고    scopus 로고
    • A novel cell-based therapy for contusion spinal cord injury using GDNF-delivering NIH3T3 cells with dual reporter genes monitored by molecular imaging
    • Lo, W. C.; Hsu, C. H.; Wu, A. T.; Yang, L. Y.; Chen, W. H.; Chiu, W. T.; Lai, W. F.; Wu, C. H.; Gelovani, J. G.; Deng, W. P. A novel cell-based therapy for contusion spinal cord injury using GDNF-delivering NIH3T3 cells with dual reporter genes monitored by molecular imaging. J. Nucl. Med. 49(9):1512-1519; 2008.
    • (2008) J. Nucl. Med. , vol.49 , Issue.9 , pp. 1512-1519
    • Lo, W.C.1    Hsu, C.H.2    Wu, A.T.3    Yang, L.Y.4    Chen, W.H.5    Chiu, W.T.6    Lai, W.F.7    Wu, C.H.8    Gelovani, J.G.9    Deng, W.P.10
  • 44
    • 77957724114 scopus 로고    scopus 로고
    • Cyclosporin A increases recovery after spinal cord injury but does not improve myelination by oligodendrocyte progenitor cell transplantation
    • Lu, H. Z.; Wang, Y. X.; Zhou, J. S.; Wang, F. C.; Hu, J. G. Cyclosporin A increases recovery after spinal cord injury but does not improve myelination by oligodendrocyte progenitor cell transplantation. BMC Neurosci. 11:127; 2010.
    • (2010) BMC Neurosci. , vol.11 , pp. 127
    • Lu, H.Z.1    Wang, Y.X.2    Zhou, J.S.3    Wang, F.C.4    Hu, J.G.5
  • 45
    • 0035817425 scopus 로고    scopus 로고
    • Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons
    • Lu, P.; Blesch, A.; Tuszynski, M. H. Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons. J. Comp. Neurol. 436(4):456-470; 2001.
    • (2001) J. Comp. Neurol. , vol.436 , Issue.4 , pp. 456-470
    • Lu, P.1    Blesch, A.2    Tuszynski, M.H.3
  • 47
    • 33646589292 scopus 로고    scopus 로고
    • Demyelination and remyelination after spinal cord injury
    • McDonald, J. W.; Belegu, V. Demyelination and remyelination after spinal cord injury. J. Neurotrauma 23(3-4):345-359; 2006.
    • (2006) J. Neurotrauma , vol.23 , Issue.3-4 , pp. 345-359
    • McDonald, J.W.1    Belegu, V.2
  • 49
    • 0032528159 scopus 로고    scopus 로고
    • Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord
    • McTigue, D. M.; Horner, P. J.; Stokes, B. T.; Gage, F. H. Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord. J. Neurosci. 18(14):5354-5365; 1998.
    • (1998) J. Neurosci. , vol.18 , Issue.14 , pp. 5354-5365
    • McTigue, D.M.1    Horner, P.J.2    Stokes, B.T.3    Gage, F.H.4
  • 50
    • 0035873062 scopus 로고    scopus 로고
    • Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord
    • McTigue, D. M.; Wei, P.; Stokes, B. T. Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord. J. Neurosci. 21(10):3392-3400; 2001.
    • (2001) J. Neurosci. , vol.21 , Issue.10 , pp. 3392-3400
    • McTigue, D.M.1    Wei, P.2    Stokes, B.T.3
  • 51
    • 22044438251 scopus 로고    scopus 로고
    • Transplants of fibroblasts expressing BDNF and NT-3 promote recovery of bladder and hindlimb function following spinal contusion injury in rats
    • Mitsui, T.; Fischer, I.; Shumsky, J. S.; Murray, M. Transplants of fibroblasts expressing BDNF and NT-3 promote recovery of bladder and hindlimb function following spinal contusion injury in rats. Exp. Neurol. 194(2):410-431; 2005.
    • (2005) Exp. Neurol. , vol.194 , Issue.2 , pp. 410-431
    • Mitsui, T.1    Fischer, I.2    Shumsky, J.S.3    Murray, M.4
  • 52
    • 33845393073 scopus 로고    scopus 로고
    • Bone marrow stromal cells for repair of the spinal cord: Towards clinical application
    • Nandoe Tewarie, R. D.; Hurtado, A.; Levi, A. D.; Grotenhuis, J. A.; Oudega, M. Bone marrow stromal cells for repair of the spinal cord: Towards clinical application. Cell Transplant. 15(7):563-577; 2006.
    • (2006) Cell Transplant. , vol.15 , Issue.7 , pp. 563-577
    • Nandoe Tewarie, R.D.1    Hurtado, A.2    Levi, A.D.3    Grotenhuis, J.A.4    Oudega, M.5
  • 53
    • 13844289150 scopus 로고    scopus 로고
    • Axon growth and recovery of function supported by human bone marrow stromal cells in the injured spinal cord exhibit donor variations
    • Neuhuber, B.; Timothy Himes, B.; Shumsky, J. S.; Gallo, G.; Fischer, I. Axon growth and recovery of function supported by human bone marrow stromal cells in the injured spinal cord exhibit donor variations. Brain Res. 1035(1):73-85; 2005.
    • (2005) Brain Res. , vol.1035 , Issue.1 , pp. 73-85
    • Neuhuber, B.1    Timothy Himes, B.2    Shumsky, J.S.3    Gallo, G.4    Fischer, I.5
  • 55
    • 33746070459 scopus 로고    scopus 로고
    • Cellular repair strategies for spinal cord injury
    • Pearse, D. D.; Barakat, D. J. Cellular repair strategies for spinal cord injury. Expert Opin. Biol. Ther. 6(7):639-652; 2006.
    • (2006) Expert Opin. Biol. Ther. , vol.6 , Issue.7 , pp. 639-652
    • Pearse, D.D.1    Barakat, D.J.2
  • 56
    • 0033485750 scopus 로고    scopus 로고
    • Donor variation in the growth properties and osteogenic potential of human marrow stromal cells
    • Phinney, D. G.; Kopen, G.; Righter, W.; Webster, S.; Tremain, N.; Prockop, D. J. Donor variation in the growth properties and osteogenic potential of human marrow stromal cells. J. Cell. Biochem. 75(3):424-436; 1999.
    • (1999) J. Cell. Biochem. , vol.75 , Issue.3 , pp. 424-436
    • Phinney, D.G.1    Kopen, G.2    Righter, W.3    Webster, S.4    Tremain, N.5    Prockop, D.J.6
  • 57
    • 36249021493 scopus 로고    scopus 로고
    • Concise review: Mesenchymal stem/multipotent stromal cells: The state of transdifferentiation and modes of tissue repair-current views
    • Phinney, D. G.; Prockop, D. J. Concise review: Mesenchymal stem/multipotent stromal cells: The state of transdifferentiation and modes of tissue repair-current views. Stem Cells 25(11):2896-2902; 2007.
    • (2007) Stem Cells , vol.25 , Issue.11 , pp. 2896-2902
    • Phinney, D.G.1    Prockop, D.J.2
  • 58
    • 33845932921 scopus 로고    scopus 로고
    • Transplantation of fibroblasts that overexpress matrix metalloproteinase-3 into the site of spinal cord injury in rats
    • Pizzi, M. A.; Crowe, M. J. Transplantation of fibroblasts that overexpress matrix metalloproteinase-3 into the site of spinal cord injury in rats. J. Neurotrauma 23(12):1750-1765; 2006.
    • (2006) J. Neurotrauma , vol.23 , Issue.12 , pp. 1750-1765
    • Pizzi, M.A.1    Crowe, M.J.2
  • 59
    • 0037263790 scopus 로고    scopus 로고
    • Delayed transplantation of olfactory ensheathing glia promotes sparing/regeneration of supraspinal axons in the contused adult rat spinal cord
    • Plant, G. W.; Christensen, C. L.; Oudega, 59. M.; Bunge, M. B. Delayed transplantation of olfactory ensheathing glia promotes sparing/regeneration of supraspinal axons in the contused adult rat spinal cord. J. Neurotrauma 20(1):1-16; 2003.
    • (2003) J. Neurotrauma , vol.20 , Issue.1 , pp. 1-16
    • Plant, G.W.1    Christensen, C.L.2    Oudega, M.3    Bunge, M.B.4
  • 60
    • 0037216605 scopus 로고    scopus 로고
    • Manipulating neuroinflammatory reactions in the injured spinal cord: Back to basics
    • Popovich, P. G.; Jones, T. B. Manipulating neuroinflammatory reactions in the injured spinal cord: Back to basics. Trends Pharmacol. Sci. 24(1):13-17; 2003.
    • (2003) Trends Pharmacol. Sci. , vol.24 , Issue.1 , pp. 13-17
    • Popovich, P.G.1    Jones, T.B.2
  • 61
    • 34547907770 scopus 로고    scopus 로고
    • "Stemness" does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs)
    • Prockop, D. J. "Stemness" does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs). Clin. Pharmacol. Ther. 82(3):241-243; 2007.
    • (2007) Clin. Pharmacol. Ther. , vol.82 , Issue.3 , pp. 241-243
    • Prockop, D.J.1
  • 62
    • 77950801859 scopus 로고    scopus 로고
    • Enrichment for STRO-1 expression enhances the cardiovascular paracrine activity of human bone marrowderived mesenchymal cell populations
    • Psaltis, P. J.; Paton, S.; See, F.; Arthur, A.; Martin, S.; Itescu, S.; Worthley, S. G.; Gronthos, S.; Zannettino, A. C. W. Enrichment for STRO-1 expression enhances the cardiovascular paracrine activity of human bone marrowderived mesenchymal cell populations. J. Cell. Physiol. 223(2):530-540; 2010.
    • (2010) J. Cell. Physiol. , vol.223 , Issue.2 , pp. 530-540
    • Psaltis, P.J.1    Paton, S.2    See, F.3    Arthur, A.4    Martin, S.5    Itescu, S.6    Worthley, S.G.7    Gronthos, S.8    Zannettino, A.C.W.9
  • 63
    • 0035008642 scopus 로고    scopus 로고
    • Cyclosporin A treatment following spinal cord injury to the rat: Behavioral effects and stereological assessment of tissue sparing
    • Rabchevsky, A. G.; Fugaccia, I.; Sullivan, P. G.; Scheff, S. W. Cyclosporin A treatment following spinal cord injury to the rat: Behavioral effects and stereological assessment of tissue sparing. J. Neurotrauma 18(5):513-522; 2001.
    • (2001) J. Neurotrauma , vol.18 , Issue.5 , pp. 513-522
    • Rabchevsky, A.G.1    Fugaccia, I.2    Sullivan, P.G.3    Scheff, S.W.4
  • 64
    • 0035704718 scopus 로고    scopus 로고
    • The athymic nude rat: An animal experimental model to reveal novel aspects of innate immune responses?
    • Rolstad, B. The athymic nude rat: An animal experimental model to reveal novel aspects of innate immune responses? Immunol. Rev. 184:136-144; 2001.
    • (2001) Immunol. Rev. , vol.184 , pp. 136-144
    • Rolstad, B.1
  • 65
    • 33646558913 scopus 로고    scopus 로고
    • Olfactory ensheathing cells: Characteristics, genetic engineering, and therapeutic potential
    • Ruitenberg, M. J.; Vukovic, J.; Sarich, J.; Busfield, S. J.; Plant, G. W. Olfactory ensheathing cells: Characteristics, genetic engineering, and therapeutic potential. J. Neurotrauma 23(3-4):468-478; 2006.
    • (2006) J. Neurotrauma , vol.23 , Issue.3-4 , pp. 468-478
    • Ruitenberg, M.J.1    Vukovic, J.2    Sarich, J.3    Busfield, S.J.4    Plant, G.W.5
  • 66
    • 0035866039 scopus 로고    scopus 로고
    • Beneficial immune activity after CNS injury: Prospects for vaccination
    • Schwartz, M.; Moalem, G. Beneficial immune activity after CNS injury: Prospects for vaccination. J. Neuroimmunol. 113(2):185-192; 2001.
    • (2001) J. Neuroimmunol. , vol.113 , Issue.2 , pp. 185-192
    • Schwartz, M.1    Moalem, G.2
  • 67
    • 0034886787 scopus 로고    scopus 로고
    • Rat marrow stromal cells rapidly transduced with a self-inactivating retrovirus synthesize L-DOPA in vitro
    • Schwarz, E. J.; Reger, R. L.; Alexander, G. M.; Class, R.; Azizi, S. A.; Prockop, D. J. Rat marrow stromal cells rapidly transduced with a self-inactivating retrovirus synthesize L-DOPA in vitro. Gene Ther. 8(16):1214-1223; 2001.
    • (2001) Gene Ther. , vol.8 , Issue.16 , pp. 1214-1223
    • Schwarz, E.J.1    Reger, R.L.2    Alexander, G.M.3    Class, R.4    Azizi, S.A.5    Prockop, D.J.6
  • 68
    • 0036456669 scopus 로고    scopus 로고
    • Expansion of human adult stem cells from bone marrow stroma: Conditions that maximize the yields of early progenitors and evaluate their quality
    • Sekiya, I.; Larson, B. L.; Smith, J. R.; Pochampally, R.; Cui, J. G.; Prockop, D. J. Expansion of human adult stem cells from bone marrow stroma: Conditions that maximize the yields of early progenitors and evaluate their quality. Stem Cells 20(6):530-541; 2002.
    • (2002) Stem Cells , vol.20 , Issue.6 , pp. 530-541
    • Sekiya, I.1    Larson, B.L.2    Smith, J.R.3    Pochampally, R.4    Cui, J.G.5    Prockop, D.J.6
  • 69
    • 0345495676 scopus 로고    scopus 로고
    • Delayed transplantation of fibroblasts genetically modified to secrete BDNF and NT-3 into a spinal cord injury site is associated with limited recovery of function
    • Shumsky, J. S.; Tobias, C. A.; Tumolo, M.; Long, W. D.; Giszter, S. F.; Murray, M. Delayed transplantation of fibroblasts genetically modified to secrete BDNF and NT-3 into a spinal cord injury site is associated with limited recovery of function. Exp. Neurol. 184(1):114-130; 2003.
    • (2003) Exp. Neurol. , vol.184 , Issue.1 , pp. 114-130
    • Shumsky, J.S.1    Tobias, C.A.2    Tumolo, M.3    Long, W.D.4    Giszter, S.F.5    Murray, M.6
  • 70
    • 0025741349 scopus 로고
    • Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1
    • Simmons, P. J.; Torok-Storb, B. Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. Blood 78(1):55-62; 1991.
    • (1991) Blood , vol.78 , Issue.1 , pp. 55-62
    • Simmons, P.J.1    Torok-Storb, B.2
  • 71
    • 32644438233 scopus 로고    scopus 로고
    • Mesenchymal stem cell-natural killer cell interactions: Evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation
    • Spaggiari, G. M.; Capobianco, A.; Becchetti, S.; Mingari, M. C.; Moretta, L. Mesenchymal stem cell-natural killer cell interactions: Evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation. Blood 107(4):1484-1490; 2006.
    • (2006) Blood , vol.107 , Issue.4 , pp. 1484-1490
    • Spaggiari, G.M.1    Capobianco, A.2    Becchetti, S.3    Mingari, M.C.4    Moretta, L.5
  • 72
    • 79955931114 scopus 로고    scopus 로고
    • Axonal regeneration effects of Wnt3a-secreting fibroblast transplantation in spinal cord-injured rats
    • Suh, H. I.; Min, J.; Choi, K. H.; Kim, S. W.; Kim, K. S.; Jeon, S. R. Axonal regeneration effects of Wnt3a-secreting fibroblast transplantation in spinal cord-injured rats. Acta Neurochir. 153(5):1003-1010; 2011.
    • (2011) Acta Neurochir. , vol.153 , Issue.5 , pp. 1003-1010
    • Suh, H.I.1    Min, J.2    Choi, K.H.3    Kim, S.W.4    Kim, K.S.5    Jeon, S.R.6
  • 74
    • 33845549165 scopus 로고    scopus 로고
    • Bone marrow stem cells and polymer hydrogels-two strategies for spinal cord injury repair
    • Sykova, E.; Jendelova, P.; Urdzikova, L.; Lesny, P.; Hejcl, A. Bone marrow stem cells and polymer hydrogels-two strategies for spinal cord injury repair. Cell. Mol. Neurobiol. 26:1113-1129; 2006.
    • (2006) Cell. Mol. Neurobiol. , vol.26 , pp. 1113-1129
    • Sykova, E.1    Jendelova, P.2    Urdzikova, L.3    Lesny, P.4    Hejcl, A.5
  • 75
    • 25144486230 scopus 로고    scopus 로고
    • Cytokine-induced stable neuronal differentiation of human bone marrow mesenchymal stem cells in a serum/feeder cell-free condition
    • Tao, H.; Rao, R.; Ma, D. D. Cytokine-induced stable neuronal differentiation of human bone marrow mesenchymal stem cells in a serum/feeder cell-free condition. Dev. Growth Differ. 47(6):423-433; 2005.
    • (2005) Dev. Growth Differ. , vol.47 , Issue.6 , pp. 423-433
    • Tao, H.1    Rao, R.2    Ma, D.D.3
  • 76
    • 0345303936 scopus 로고    scopus 로고
    • Neurotrophic effects on dorsal root regeneration into the spinal cord
    • Tessler, A. Neurotrophic effects on dorsal root regeneration into the spinal cord. Prog. Brain Res. 143:147-154; 2004.
    • (2004) Prog. Brain Res. , vol.143 , pp. 147-154
    • Tessler, A.1
  • 78
    • 19944433307 scopus 로고    scopus 로고
    • Alginate encapsulated BDNF-producing fibroblast grafts permit recovery of function after spinal cord injury in the absence of immune suppression
    • Tobias, C. A.; Han, S. S.; Shumsky, J. S.; Kim, D.; Tumolo, M.; Dhoot, N. O.; Wheatley, M. A.; Fischer, I.; Tessler, A.; Murray, M. Alginate encapsulated BDNF-producing fibroblast grafts permit recovery of function after spinal cord injury in the absence of immune suppression. J. Neurotrauma 22(1):138-156; 2005.
    • (2005) J. Neurotrauma , vol.22 , Issue.1 , pp. 138-156
    • Tobias, C.A.1    Han, S.S.2    Shumsky, J.S.3    Kim, D.4    Tumolo, M.5    Dhoot, N.O.6    Wheatley, M.A.7    Fischer, I.8    Tessler, A.9    Murray, M.10
  • 79
    • 0345227300 scopus 로고    scopus 로고
    • Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration
    • Tobias, C. A.; Shumsky, J. S.; Shibata, M.; Tuszynski, M. H.; Fischer, I.; Tessler, A.; Murray, M. Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration. Exp. Neurol. 184(1):97-113; 2003.
    • (2003) Exp. Neurol. , vol.184 , Issue.1 , pp. 97-113
    • Tobias, C.A.1    Shumsky, J.S.2    Shibata, M.3    Tuszynski, M.H.4    Fischer, I.5    Tessler, A.6    Murray, M.7
  • 80
    • 0033139716 scopus 로고    scopus 로고
    • Recovery of locomotion after experimental spinal cord injury: Axonal regeneration or modulation of intrinsic spinal cord walking circuitry? J
    • Tuszynski, M.; Edgerton, R.; Dobkin, B. Recovery of locomotion after experimental spinal cord injury: Axonal regeneration or modulation of intrinsic spinal cord walking circuitry? J. Spinal Cord Med. 22(2):143; 1999.
    • (1999) Spinal Cord Med. , vol.22 , Issue.2 , pp. 143
    • Tuszynski, M.1    Edgerton, R.2    Dobkin, B.3
  • 81
    • 0037099992 scopus 로고    scopus 로고
    • Spontaneous and augmented growth of axons in the primate spinal cord: Effects of local injury and nerve growth factor-secreting cell grafts
    • Tuszynski, M. H.; Grill, R.; Jones, L. L.; McKay, H. M.; Blesch, A. Spontaneous and augmented growth of axons in the primate spinal cord: Effects of local injury and nerve growth factor-secreting cell grafts. J. Comp. Neurol. 449(1):88-101; 2002.
    • (2002) J. Comp. Neurol. , vol.449 , Issue.1 , pp. 88-101
    • Tuszynski, M.H.1    Grill, R.2    Jones, L.L.3    McKay, H.M.4    Blesch, A.5
  • 83
    • 15544376664 scopus 로고    scopus 로고
    • Plasticity of cultured mesenchymal stem cells: Switch from nestin-positive to excitable neuron-like phenotype
    • Wislet-Gendebien, S.; Hans, G.; Leprince, P.; Rigo, J. M.; Moonen, G.; Rogister, B. Plasticity of cultured mesenchymal stem cells: Switch from nestin-positive to excitable neuron-like phenotype. Stem Cells 23(3):392-402; 2005.
    • (2005) Stem Cells , vol.23 , Issue.3 , pp. 392-402
    • Wislet-Gendebien, S.1    Hans, G.2    Leprince, P.3    Rigo, J.M.4    Moonen, G.5    Rogister, B.6
  • 85
    • 34547915244 scopus 로고    scopus 로고
    • Complete spinal cord injury treatment using autologous bone marrow cell transplantation and bone marrow stimulation with granulocyte macrophage-colony stimulating factor: Phase I/II clinical trial
    • Yoon, S. H.; Shim, Y. S.; Park, Y. H.; Chung, J. K.; Nam, J. H.; Kim, M. O.; Park, H. C.; Park, S. R.; Min, B. H.; Kim, E. Y.; Choi, B. H.; Park, H.; Ha, Y. Complete spinal cord injury treatment using autologous bone marrow cell transplantation and bone marrow stimulation with granulocyte macrophage-colony stimulating factor: Phase I/II clinical trial. Stem Cells 25(8):2066-2073; 2007.
    • (2007) Stem Cells , vol.25 , Issue.8 , pp. 2066-2073
    • Yoon, S.H.1    Shim, Y.S.2    Park, Y.H.3    Chung, J.K.4    Nam, J.H.5    Kim, M.O.6    Park, H.C.7    Park, S.R.8    Min, B.H.9    Kim, E.Y.10    Choi, B.H.11    Park, H.12    Ha, Y.13


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