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Volumn 34, Issue 4, 2013, Pages 487-495

Safflor yellow A protects neonatal rat cardiomyocytes against anoxia/reoxygenation injury in vitro

Author keywords

Anoxia reoxygenation; Antioxidant; Apoptosis; Cardiomyocyte; N acetylcysteine; Oxidative stress; Safflor yellow A

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; 4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ACETYLCYSTEINE; CASPASE 3; CATALASE; CREATINE KINASE; FLAVONOID; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LACTATE DEHYDROGENASE; MALONALDEHYDE; PROTEIN BAX; PROTEIN BCL 2; SAFFLOR YELLOW A; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

EID: 84877249737     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2012.185     Document Type: Article
Times cited : (36)

References (64)
  • 1
    • 0037400919 scopus 로고    scopus 로고
    • Melatonin: A novel protective agent against oxidative injury of the ischemic/reperfused heart
    • DOI 10.1016/S0008-6363(02)00827-1
    • Reiter RJ, Tan DX. Melatonin: A novel protective agent against oxidative injury of the ischemic/reperfused heart. Cardiovasc Res 2003; 58: 10-9 (Pubitemid 36351618)
    • (2003) Cardiovascular Research , vol.58 , Issue.1 , pp. 10-19
    • Reiter, R.J.1    Tan, D.-X.2
  • 2
    • 0026766132 scopus 로고
    • Oxygen free radicals and cardiac reperfusion abnormalities
    • Goldhaber JI, Weiss JN. Oxygen free radicals and cardiac reperfusion abnormalities. Hypertension 1992; 20: 118-27
    • (1992) Hypertension , vol.20 , pp. 118-127
    • Goldhaber, J.I.1    Weiss, J.N.2
  • 3
    • 0032923593 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of myocardial stunning
    • Bolli R, Marban E. Molecular and cellular mechanisms of myocardial stunning. Physiol Rev 1999; 79: 609-34 (Pubitemid 29210931)
    • (1999) Physiological Reviews , vol.79 , Issue.2 , pp. 609-634
    • Bolli, R.1    Marban, E.2
  • 4
    • 0018415252 scopus 로고
    • Mechanical and biochemical effects of transient myocardial ischemia
    • Hess ML, Barnhart GR, Crute S, Komwatana P, Krause S, Greenfield LJ. Mechanical and biochemical effects of transient myocardial ischemia. J Surg Res 1979; 26: 175-84 (Pubitemid 9142162)
    • (1979) Journal of Surgical Research , vol.26 , Issue.2 , pp. 175-184
    • Hess, M.L.1    Barnhart, G.R.2    Crute, S.3
  • 6
    • 0028196994 scopus 로고
    • Myocardial reperfusion injury: Role of oxygen radicals and potential therapy with antioxidants
    • Jeroudi MO, Hartley CJ, Bolli R. Myocardial reperfusion injury: Role of oxygen radicals and potential therapy with antioxidants. Am J Cardiol 1994; 73: 2B-7B. (Pubitemid 24093495)
    • (1994) American Journal of Cardiology , vol.73 , Issue.6
    • Jeroudi, M.O.1    Hartley, C.J.2    Bolli, R.3
  • 7
    • 0020414455 scopus 로고
    • The stunned myocardium: Prolonged, postischemic ventricular dysfunction
    • Braunwald E, Kloner RA. The stunned myocardium: Prolonged, postischemic ventricular dysfunction. Circulation 1982; 66: 1146-9 (Pubitemid 13238825)
    • (1982) Circulation , vol.66 , Issue.6 I , pp. 1146-1149
    • Braunwald, E.1    Kloner, R.A.2
  • 10
    • 0032526374 scopus 로고    scopus 로고
    • Apoptosis: Basic mechanisms and implications for cardiovascular disease
    • Haunstetter A, Izumo S. Apoptosis: Basic mechanisms and implications for cardiovascular disease. Circ Res 1998; 82: 1111-29 (Pubitemid 28311120)
    • (1998) Circulation Research , vol.82 , Issue.11 , pp. 1111-1129
    • Haunstetter, A.1    Izumo, S.2
  • 12
    • 0842287487 scopus 로고    scopus 로고
    • Mechanisms of Apoptosis in the Heart
    • DOI 10.1023/B:JOCI.0000010421.56035.60
    • Gustafsson AB, Gottlieb RA. Mechanisms of apoptosis in the heart. J Clin Immunol 2003; 23: 447-59 (Pubitemid 38177666)
    • (2003) Journal of Clinical Immunology , vol.23 , Issue.6 , pp. 447-459
    • Gustafsson, A.B.1    Gottlieb, R.A.2
  • 13
    • 34548681835 scopus 로고    scopus 로고
    • Protective roles of puerarin and Danshensu on acute ischemic myocardial injury in rats
    • DOI 10.1016/j.phymed.2007.07.060, PII S0944711307001845
    • Wua L, Qiao H. Protective roles of puerarin and Danshensu on acute ischemic myocardial injury in rats. Phytomedicine 2007; 14: 652-8 (Pubitemid 47419302)
    • (2007) Phytomedicine , vol.14 , Issue.10 , pp. 652-658
    • Wu, L.1    Qiao, H.2    Li, Y.3    Li, L.4
  • 14
    • 33747178144 scopus 로고    scopus 로고
    • Protective effects of hydroxysafflor yellow A on acute myocardial ischemia in dogs
    • Li XZ, Liu JX, Shang XH, Fu JH. Protective effects of hydroxysafflor yellow A on acute myocardial ischemia in dogs. Chin Pharmacol Bull 2006; 6: 533-7
    • (2006) Chin Pharmacol Bull , vol.6 , pp. 533-537
    • Li, X.Z.1    Liu, J.X.2    Shang, X.H.3    Fu, J.H.4
  • 15
    • 0242291805 scopus 로고    scopus 로고
    • The preventive effects of safflor yellow on myocardium injury of mycardium ischemic reperfusion in rats
    • Zheng WC, Chen DB, Li B, Zhang L. The preventive effect safflor yellow on myocardium injury of myocardium ischemic reperfusion in rats. Chin Pharmacol Bull 2003; 19: 1032-4 (Pubitemid 37345517)
    • (2003) Chinese Pharmacological Bulletin , vol.19 , Issue.9 , pp. 1032-1034
    • Zheng, W.-C.1    Chen, D.-B.2    Li, B.3    Zhang, L.4
  • 16
    • 0000666747 scopus 로고
    • A cathartic lignan glycoside isolated from carthamus tinctorus
    • Palter R, Lundin RE, Haddon WF. A cathartic lignan glycoside isolated from carthamus tinctorus. Phytochemistry 1972; 11: 2871-4
    • (1972) Phytochemistry , vol.11 , pp. 2871-2874
    • Palter, R.1    Lundin, R.E.2    Haddon, W.F.3
  • 18
    • 0030481770 scopus 로고    scopus 로고
    • Triterpene alcohols from the flowers of compositae and their anti- inflammatory effects
    • DOI 10.1016/S0031-9422(96)00343-3, PII S0031942296003433
    • Akihisa T, Yasukawa K, Oinuma H, Kasahara Y, Yamanouchi S, Takido M, et al. Triterpene alcohols from the flowers of compositae and their anti-inflammatory effects. Phytochemistry 1996; 43: 1255-60 (Pubitemid 27108304)
    • (1996) Phytochemistry , vol.43 , Issue.6 , pp. 1255-1260
    • Akihisa, T.1    Yasukawa, K.2    Oinuma, H.3    Kasahara, Y.4    Yamanouchi, S.5    Takido, M.6    Kumaki, K.7    Tamura, T.8
  • 19
    • 0031425441 scopus 로고    scopus 로고
    • Immunomodulating activities of polysaccharide fractions from dried safflower petals
    • Hirokawa T, Hirokawa S, Yamauchi N, Kataoka T, Woo JT, Nagai K. Immunomodulating activities of polysaccharide fractions from dried safflower petals. Cytotechnology 1997; 25: 205-11 (Pubitemid 28110881)
    • (1997) Cytotechnology , vol.25 , Issue.1-3 , pp. 205-211
    • Wakabayashi, T.1    Hirokawa, S.2    Yamauchi, N.3    Kataoka, T.4    Woo, J.-T.5    Nagai, K.6
  • 20
    • 1542692563 scopus 로고
    • Separation and identification of safflower yellow A and carthamin from Carthamus tinctorius L
    • An XQ, Li YH, Chen J. Separation and identification of safflower yellow A and carthamin from Carthamus tinctorius L. Chin Tradit Herb Drugs 1990; 21: 188-9
    • (1990) Chin Tradit Herb Drugs , vol.21 , pp. 188-189
    • An, X.Q.1    Li, Y.H.2    Chen, J.3
  • 22
    • 0034681741 scopus 로고    scopus 로고
    • A novel semi-quinone chalcone sharing a pyrrole ring C-glycoside from carthamus tinctorius
    • Yin HB, He ZS. A novel semi-quinone chalcone sharing a pyrrole ring C-glycoside from carthamus tinctorius. Tetrahedrom Lett 2000; 41: 1955-8
    • (2000) Tetrahedrom Lett , vol.41 , pp. 1955-1958
    • Yin, H.B.1    He, Z.S.2
  • 25
    • 67449164339 scopus 로고    scopus 로고
    • Safflor yellow B suppresses pheochromocytoma cell (PC 12) injury induced by oxidative stress via antioxidant system and Bcl-2 /Bax pathway
    • Wang CY, Ma HM, Zhang SP. Safflor yellow B suppresses pheochromocytoma cell (PC 12) injury induced by oxidative stress via antioxidant system and Bcl-2 /Bax pathway. Naunyn Schmiedebergs Arch Pharmacol 2009; 380: 135-42
    • (2009) Naunyn Schmiedebergs Arch Pharmacol , vol.380 , pp. 135-142
    • Wang, C.Y.1    Ma, H.M.2    Zhang, S.P.3
  • 26
    • 67349133846 scopus 로고    scopus 로고
    • The protective effects of hydroxysafflower yellow A on hypoxia cardiomyocyte
    • Xue HY, Wei XB, Ding H. The protective effects of hydroxysafflower yellow A on hypoxia cardiomyocyte. Zhongguo Lao Nian Xue Za Zhi 2007; 7: 140-2
    • (2007) Zhongguo Lao Nian Xue Za Zhi , vol.7 , pp. 140-142
    • Xue, H.Y.1    Wei, X.B.2    Ding, H.3
  • 27
    • 22544451583 scopus 로고    scopus 로고
    • Hydroxysafflor yellow A protects rat brains against ischemia-reperfusion injury by antioxidant action
    • Wei XB, Liu XQ. Hydroxysafflor yellow A protects rat brains against ischemia-reperfusion injury by antioxidant action. Neurosci Lett 2005; 386: 58-62
    • (2005) Neurosci Lett , vol.386 , pp. 58-62
    • Wei, X.B.1    Liu, X.Q.2
  • 28
    • 84866025065 scopus 로고    scopus 로고
    • Upregulation of heme oxygenase-1 expression by hydroxysafflor yellow A conferring protection from anoxia/reoxygenation-induced apoptosis in H9c2 cardiomyocytes
    • Liu SX, Zhang X, Wang YF, Li XC, Xiang MX, Bian C, et al. Upregulation of heme oxygenase-1 expression by hydroxysafflor yellow A conferring protection from anoxia/reoxygenation-induced apoptosis in H9c2 cardiomyocytes. Int J Cardiol 2012; 160: 95-101
    • (2012) Int J Cardiol , vol.160 , pp. 95-101
    • Liu, S.X.1    Zhang, X.2    Wang, Y.F.3    Li, X.C.4    Xiang, M.X.5    Bian, C.6
  • 30
    • 0026055730 scopus 로고
    • Reperfusion-induced contracture develops with a decreasing [Ca2+] in single heart cells
    • Koyama T, Temma K, Akera T. Reperfusion-induced contracture develops with a decreasing [Ca2+] in single heart cells. Am J Physiol 1991; 261: H1115-22
    • (1991) Am J Physiol , vol.261
    • Koyama, T.1    Temma, K.2    Akera, T.3
  • 31
    • 0032515948 scopus 로고    scopus 로고
    • Tumor necrosis factor-α confers resistance to hypoxic injury in the adult mammalian cardiac myocyte
    • Nakano M, Knowlton AA, Dibbs Z, Mann DL. Tumor necrosis factoralpha confers resistance to hypoxic injury in the adult mammalian cardiac myocyte. Circulation 1998; 97: 1392-400 (Pubitemid 28182678)
    • (1998) Circulation , vol.97 , Issue.14 , pp. 1392-1400
    • Nakano, M.1    Knowlton, A.A.2    Dibbs, Z.3    Mann, D.L.4
  • 32
    • 33745853187 scopus 로고    scopus 로고
    • Hypoxic postconditioning enhances the survival and inhibits apoptosis of cardiomyocytes following reoxygenation: Role of peroxynitrite formation
    • DOI 10.1007/s10495-006-7786-z
    • Wang HC, Zhang HF, Guo WY, Su H, Zhang KR, Li QX, et al. Hypoxic postconditioning enhances the survival and inhibits apoptosis of cardiomyocytes following reoxygenation: Role of peroxynitrite formation. Apoptosis 2006; 11: 1453-60 (Pubitemid 44035955)
    • (2006) Apoptosis , vol.11 , Issue.8 , pp. 1453-1460
    • Wang, H.-C.1    Zhang, H.-F.2    Guo, W.-Y.3    Su, H.4    Zhang, K.-R.5    Li, Q.-X.6    Yan, W.7    Ma, X.L.8    Lopez, B.L.9    Christopher, T.A.10    Gao, F.11
  • 33
    • 76649130232 scopus 로고    scopus 로고
    • Changes in the levels of MDA and GSH in mice serum, liver and spleen after aluminum administration
    • Turguta G, Enlib Y. Changes in the levels of MDA and GSH in mice serum, liver and spleen after aluminum administration. East J Med 2006; 11: 7-12
    • (2006) East J Med , vol.11 , pp. 7-12
    • Turguta, G.1    Enlib, Y.2
  • 34
    • 0000604386 scopus 로고
    • Rapid, sensitive, and specific thiobarbituric acid method for measuring lipid peroxidation in animal tissue, food, and feedstuff samples
    • Botsoglou NA, Fletouris DJ. Rapid, sensitive, and specific thiobarbituric acid method for measuring lipid peroxidation in animal tissue, food, and feedstuff samples. J Agric Food Chem 1994; 42: 1931-7
    • (1994) J Agric Food Chem , vol.42 , pp. 1931-1937
    • Botsoglou, N.A.1    Fletouris, D.J.2
  • 36
    • 0037400114 scopus 로고    scopus 로고
    • Cyanidin-3-O-β-glucopyranoside protects myocardium and erythrocytes from oxygen radical-mediated damages
    • DOI 10.1080/1071576021000055253
    • Amorini AM, Lazzarino G, Galvano F, Fazzina G, Tavazzi B, Galvano G. Cyanidin-3-O-beta-glucopyranoside protects myocardium and erythrocytes from oxygen radical-mediated damages. Free Radic Res 2003; 37: 453-60 (Pubitemid 36244897)
    • (2003) Free Radical Research , vol.37 , Issue.4 , pp. 453-460
    • Amorini, A.M.1    Lazzarino, G.2    Galvano, F.3    Fazzina, G.4    Tavazzi, B.5    Galvano, G.6
  • 37
    • 15544383014 scopus 로고    scopus 로고
    • Effects of different fractions of a red wine non-alcoholic extract on ischemia-reperfusion injury
    • DOI 10.1016/j.lfs.2004.10.044
    • Fantinelli JC, Schinella G, Cingolani HE, Mosca SM. Effects of different fractions of a red wine non-Alcoholic extract on ischemiareperfusion injury. Life Sci 2005; 76: 2721-33 (Pubitemid 40404059)
    • (2005) Life Sciences , vol.76 , Issue.23 , pp. 2721-2733
    • Fantinelli, J.C.1    Schinella, G.2    Cingolani, H.E.3    Mosca, S.M.4
  • 38
    • 33846845077 scopus 로고    scopus 로고
    • Protective effects of EGCg or GCg, a green tea catechin epimer, against postischemic myocardial dysfunction in guinea-pig hearts
    • DOI 10.1016/j.lfs.2006.11.032, PII S0024320506009167
    • Hirai M, Hotta Y, Ishikawa N, Wakida Y, Fukuzawa Y, Isobe F, et al. Protective effects of EGCg or GCg, a green tea catechin epimer, against postischemic myocardial dysfunction in guinea-pig hearts. Life Sci 2007; 80: 1020-32 (Pubitemid 46204721)
    • (2007) Life Sciences , vol.80 , Issue.11 , pp. 1020-1032
    • Hirai, M.1    Hotta, Y.2    Ishikawa, N.3    Wakida, Y.4    Fukuzawa, Y.5    Isobe, F.6    Nakano, A.7    Chiba, T.8    Kawamura, N.9
  • 40
    • 7444239011 scopus 로고    scopus 로고
    • Epigallocatechin, a green tea polyphenol, attenuates myocardial ischemia reperfusion injury in rats
    • Aneja R, Hake PW, Burroughs TJ, Denenberg AG, Wong HR, Zingarelli B. Epigallocatechin, a green tea polyphenol, attenuates myocardial ischemia reperfusion injury in rats. Mol Med 2004; 10: 55-62 (Pubitemid 39440321)
    • (2004) Molecular Medicine , vol.10 , Issue.1-6 , pp. 55-62
    • Aneja, R.1    Hake, P.W.2    Burroughs, T.J.3    Denenberg, A.G.4    Wong, H.R.5    Zingarelli, B.6
  • 41
    • 1642506168 scopus 로고    scopus 로고
    • Propyl paraben inhibits voltage-dependent sodium channels and protects cardiomyocytes from ischemia-reperfusion injury
    • DOI 10.1016/j.lfs.2003.11.007, PII S0024320504001419
    • Ji X, Xu Z, Criswell HE, Boysen PG. Propyl paraben inhibits voltagedependent sodium channels and protects cardiomyocytes from ischemia-reperfusion injury. Life Sci 2004; 74: 3043-52 (Pubitemid 38402300)
    • (2004) Life Sciences , vol.74 , Issue.24 , pp. 3043-3052
    • Ji, X.1    Xu, Z.2    Criswell, H.E.3    Boysen, P.G.4
  • 43
    • 31744452112 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine on myocardial ischemia-reperfusion injury in bypass surgery
    • DOI 10.1007/s00380-005-0873-1
    • Orhan G, Yapici N, Yuksel M, Sargin M, Senay S, Yalçin AS, et al. Effects of N-Acetylcysteine on myocardial ischemia-reperfusion injury in bypass surgery. Heart Vessels 2006; 21: 42-7 (Pubitemid 43174290)
    • (2006) Heart and Vessels , vol.21 , Issue.1 , pp. 42-47
    • Orhan, G.1    Yapici, N.2    Yuksel, M.3    Sargin, M.4    Senay, S.5    Yalcin, A.S.6    Aykac, Z.7    Aka, S.A.8
  • 44
    • 42349111318 scopus 로고    scopus 로고
    • Comparison of the protective effect of N-acetylcysteine by different treatments on rat myocardial ischemia-reperfusion injury
    • DOI 10.1254/jphs.FP0071664
    • Abe M, Takiguchi Y, Ichimaru S, Tsuchiya K, Wada K. Comparison of the protective effect of N-Acetylcysteine by different treatments on rat myocardial ischemia-reperfusion injury. J Pharmacol Sci 2008; 106: 571-7 (Pubitemid 351556235)
    • (2008) Journal of Pharmacological Sciences , vol.106 , Issue.4 , pp. 571-577
    • Abe, M.1    Takiguchi, Y.2    Ichimaru, S.3    Tsuchiya, K.4    Wada, K.5
  • 45
    • 57649221172 scopus 로고    scopus 로고
    • Discriminative cytotoxicity assessment based on various cellular damages
    • Hyunsoo K, Sung CY, Tae YL, Daewon J. Discriminative cytotoxicity assessment based on various cellular damages. Toxicol Lett 2009; 184: 13-7
    • (2009) Toxicol Lett , vol.184 , pp. 13-17
    • Hyunsoo, K.1    Sung, C.Y.2    Tae, Y.L.3    Daewon, J.4
  • 46
    • 0030880593 scopus 로고    scopus 로고
    • A very sensitive coupled luminescent assay for cytotoxicity and complement-mediated lysis
    • DOI 10.1016/S0022-1759(97)00098-7, PII S0022175997000987
    • Corey MJ, Kinders RJ, Brown LG, Vessella RL. A very sensitive coupled luminescent assay for cytotoxicity and complement-mediated lysis. J Immunol Methods 1997; 207: 43-51 (Pubitemid 27400471)
    • (1997) Journal of Immunological Methods , vol.207 , Issue.1 , pp. 43-51
    • Corey, M.J.1    Kinders, R.J.2    Brown, L.G.3    Vessella, R.L.4
  • 47
    • 34250814485 scopus 로고    scopus 로고
    • Tanshinone IIA protects cardiac myocytes against oxidative stress-Triggered damage and apoptosis
    • Fu JJ, Huang HQ, Liu JJ, Pi RB, Chen JW, Liu PQ. Tanshinone IIA protects cardiac myocytes against oxidative stress-Triggered damage and apoptosis. Eur J Pharmacol 2007; 568: 213-21
    • (2007) Eur J Pharmacol , vol.568 , pp. 213-221
    • Fu, J.J.1    Huang, H.Q.2    Liu, J.J.3    Pi, R.B.4    Chen, J.W.5    Liu, P.Q.6
  • 48
    • 70349744439 scopus 로고    scopus 로고
    • Effects of Qiangxin capsules on myocardial reperfusion arrhythmias in rats
    • Wu Y, Yuan BX. Effects of Qiangxin capsules on myocardial reperfusion arrhythmias in rats. North Phar J 2001; 16: 23-4
    • (2001) North Phar J , vol.16 , pp. 23-24
    • Wu, Y.1    Yuan, B.X.2
  • 50
    • 0028308540 scopus 로고
    • Antioxidant effectiveness in ischemia/reperfusion tissue injury
    • Das DK, Maulik N. Antioxidant effectiveness in ischemia/reperfusion tissue injury. Methods Enzymol 1994; 233: 601-10
    • (1994) Methods Enzymol , vol.233 , pp. 601-610
    • Das, D.K.1    Maulik, N.2
  • 51
    • 0033833788 scopus 로고    scopus 로고
    • Oxidative stress and cardiac disease
    • Lefer DJ, Granger DN. Oxidative stress and cardiac disease. Am J Med 2000; 109: 315-23
    • (2000) Am J Med , vol.109 , pp. 315-323
    • Lefer, D.J.1    Granger, D.N.2
  • 52
    • 32444433202 scopus 로고    scopus 로고
    • Free radicals, metals and antioxidants in oxidative stress-induced cancer
    • DOI 10.1016/j.cbi.2005.12.009, PII S0009279705004333
    • Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact 2006; 160: 1-40 (Pubitemid 43227479)
    • (2006) Chemico-Biological Interactions , vol.160 , Issue.1 , pp. 1-40
    • Valko, M.1    Rhodes, C.J.2    Moncol, J.3    Izakovic, M.4    Mazur, M.5
  • 55
    • 0028891783 scopus 로고
    • Apoptosis, oncosis, and necrosis. An overview of cell death
    • Majno G, Joris I. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 1995; 146: 3-15
    • (1995) Am J Pathol , vol.146 , pp. 3-15
    • Majno, G.1    Joris, I.2
  • 56
    • 0036858041 scopus 로고    scopus 로고
    • Oxidative stress and apoptosis in heart dysfunction
    • DOI 10.1007/s00059-002-2430-3
    • Kumar D, Lou HQ, Singal PK. Oxidative stress and apoptosis in heart dysfunction. Herz 2002; 27: 662-8 (Pubitemid 35415251)
    • (2002) Herz , vol.27 , Issue.7 , pp. 662-668
    • Kumar, D.1    Lou, H.2    Singal, P.K.3
  • 57
    • 0029778441 scopus 로고    scopus 로고
    • Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction
    • Misao J, Hayakawa Y, Ohno M, Kato S, Fujiwara T, Fujiwara H. Expres sion of Bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction. Circulation 1996; 94: 1506-12 (Pubitemid 26320251)
    • (1996) Circulation , vol.94 , Issue.7 , pp. 1506-1512
    • Misao, J.1    Hayakawa, Y.2    Ohno, M.3    Kato, S.4    Fujiwara, T.5    Fujiwara, H.6
  • 58
    • 0029032660 scopus 로고
    • Structure-function analysis of Bcl-2 protein. Identification of conserved domains important for homodimerization with Bcl-2 and heterodimerization with Bax
    • Hanada M, Aime-Sempe C, Sato T, Reed JC. Structure-function analysis of Bcl-2 protein. Identification of conserved domains important for homodimerization with Bcl-2 and heterodimerization with Bax. J Biol Chem 1995; 270: 11962-9
    • (1995) J Biol Chem , vol.270 , pp. 11962-11969
    • Hanada, M.1    Aime-Sempe, C.2    Sato, T.3    Reed, J.C.4
  • 59
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl- 2 regulation of apoptosis
    • DOI 10.1126/science.275.5303.1132
    • Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis. Science 1997; 275: 1132-6 (Pubitemid 27097313)
    • (1997) Science , vol.275 , Issue.5303 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 60
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
    • DOI 10.1126/science.275.5303.1129
    • Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, Cai J, et al. Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked. Science 1997; 275: 1129-32 (Pubitemid 27097312)
    • (1997) Science , vol.275 , Issue.5303 , pp. 1129-1132
    • Yang, J.1    Liu, X.2    Bhalla, K.3    Kim, C.N.4    Ibrado, A.M.5    Cai, J.6    Peng, T.-I.7    Jones, D.P.8    Wang, X.9
  • 61
    • 0035240260 scopus 로고    scopus 로고
    • Apoptosis: Implications of basic research for clinical oncology
    • DOI 10.1016/S1470-2045(00)00193-5, PII S1470204500001935
    • Tamm I, Schriever F, Dörken B. Apoptosis: Implications of basic research for clinical oncology. Lancet Oncol 2001; 2: 33-42 (Pubitemid 33585915)
    • (2001) Lancet Oncology , vol.2 , Issue.1 , pp. 33-42
    • Tamm, I.1    Schriever, F.2    Dorken, B.3
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.