Propyl paraben inhibits voltage-dependent sodium channels and protects cardiomyocytes from ischemia-reperfusion injury

Life Sciences

Volumn 74, Issue 24, 2004, Pages 3043-3052

  Ji, Xiang ^a   Xu, Zhelong ^a   Criswell, Hugh E ^a   Boysen, Philip G ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Cardioprotection; Cell death; Ischemia reperfusion injury; Na+ channels; Na+ overload

Indexed keywords

PROPIDIUM IODIDE; PROPYL PARABEN; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; CELL DEATH; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HYPERPOLARIZATION; MALE; NONHUMAN; RAT; RECORDING; REPERFUSION INJURY; SODIUM CURRENT; STEADY STATE; VOLTAGE CLAMP;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANIDINES; ION CHANNEL GATING; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; PARABENS; PATCH-CLAMP TECHNIQUES; PROPIDIUM; RATS; RATS, WISTAR; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; SULFONES;

EID: 1642506168     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2003.11.007     Document Type: Article

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