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Volumn 7, Issue 6, 2013, Pages 1773-1778

BDNF protects retinal neurons from hyperglycemia through the TrkB/ERK/MAPK pathway

Author keywords

Apoptosis; Brain derived neurotrophic factor; Diabetic retinopathy; ERK MAPK signaling pathway; Retinal neurons

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE;

EID: 84877244728     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1433     Document Type: Article
Times cited : (50)

References (28)
  • 1
    • 0037376768 scopus 로고    scopus 로고
    • A new view of diabetic retinopathy: A neurodegenerative disease of the eye
    • Barber AJ: A new view of diabetic retinopathy: a neurodegenerative disease of the eye. Prog Neuropsychopharmacol Biol Psychiatry 27: 283-290, 2003.
    • (2003) Prog Neuropsychopharmacol Biol Psychiatry , vol.27 , pp. 283-290
    • Barber, A.J.1
  • 2
    • 0031919598 scopus 로고    scopus 로고
    • Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy
    • Penn State Retina Research Group
    • Lieth E, Barber AJ, Xu B, et al: Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy. Penn State Retina Research Group. Diabetes 47: 815-820, 1998.
    • (1998) Diabetes , vol.47 , pp. 815-820
    • Lieth, E.1    Barber, A.J.2    Xu, B.3
  • 3
    • 0346724201 scopus 로고    scopus 로고
    • Mechanism of mitochondrial dysfunction in diabetic sensory neuropathy
    • Fernyhough P, Huang TJ and Verkhratsky A: Mechanism of mitochondrial dysfunction in diabetic sensory neuropathy. J Peripher Nerv Syst 8: 227-235, 2003.
    • (2003) J Peripher Nerv Syst , vol.8 , pp. 227-235
    • Fernyhough, P.1    Huang, T.J.2    Verkhratsky, A.3
  • 4
    • 0027522462 scopus 로고
    • Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo
    • Mey J and Thanos S: Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo. Brain Res 602: 304-317, 1993.
    • (1993) Brain Res , vol.602 , pp. 304-317
    • Mey, J.1    Thanos, S.2
  • 5
    • 0029979673 scopus 로고    scopus 로고
    • Effects of axotomy and intraocular administration of NT-4 NT-3 and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo study
    • Peinado-Ramón P, Salvador M, Villegas-Pérez MP and Vidal-Sanz M: Effects of axotomy and intraocular administration of NT-4, NT-3 and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo study. Invest Ophthalmol Vis Sci 37: 489-500, 1996.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 489-500
    • Peinado-Ramón, P.1    Salvador, M.2    Villegas-Pérez, M.P.3    Vidal-Sanz, M.4
  • 6
    • 18744433956 scopus 로고    scopus 로고
    • Effects of brain-derived neurotrophic factor on cell survival, differentiation and patterning of neuronal connections and Müller glia cells in the developing retina
    • Pinzón-Duarte G, Arango-González B, Guenther E and Kohler K: Effects of brain-derived neurotrophic factor on cell survival, differentiation and patterning of neuronal connections and Müller glia cells in the developing retina. Eur J Neurosci 19: 1475-1484, 2004.
    • (2004) Eur J Neurosci , vol.19 , pp. 1475-1484
    • Pinzón-Duarte, G.1    Arango-González, B.2    Guenther, E.3    Kohler, K.4
  • 7
    • 0034738930 scopus 로고    scopus 로고
    • Inhibition of neuroretinal cell death by insulin-like growth factor-1 and its analogs
    • Seigel GM, Chiu L and Paxhia A: Inhibition of neuroretinal cell death by insulin-like growth factor-1 and its analogs. Mol Vis 6: 157-163, 2000.
    • (2000) Mol Vis , vol.6 , pp. 157-163
    • Seigel, G.M.1    Chiu, L.2    Paxhia, A.3
  • 8
    • 36749004288 scopus 로고    scopus 로고
    • Astrocyte-derived CNTF switches mature RGCs to a regenerative state following inflammatory stimulation
    • Müller A, Hauk TG and Fischer D: Astrocyte-derived CNTF switches mature RGCs to a regenerative state following inflammatory stimulation. Brain 130: 3308-3320, 2007.
    • (2007) Brain , vol.130 , pp. 3308-3320
    • Müller, A.1    Hauk, T.G.2    Fischer, D.3
  • 9
    • 34548681632 scopus 로고    scopus 로고
    • The neural cell adhesion molecule is necessary for normal adult retinal ganglion cell number and survival
    • Murphy JA, Franklin TB, Rafuse VF and Clarke DB: The neural cell adhesion molecule is necessary for normal adult retinal ganglion cell number and survival. Mol Cell Neurosci 36: 280-292, 2007.
    • (2007) Mol Cell Neurosci , vol.36 , pp. 280-292
    • Murphy, J.A.1    Franklin, T.B.2    Rafuse, V.F.3    Clarke, D.B.4
  • 10
    • 34249725113 scopus 로고    scopus 로고
    • Expression of ciliary neurotrophic factor (CNTF) and its tripartite receptor complex by cells of the human optic nerve head
    • Liu X, Clark AF and Wordinger RJ: Expression of ciliary neurotrophic factor (CNTF) and its tripartite receptor complex by cells of the human optic nerve head. Mol Vis 13: 758-763, 2007.
    • (2007) Mol Vis , vol.13 , pp. 758-763
    • Liu, X.1    Clark, A.F.2    Wordinger, R.J.3
  • 11
    • 77949754231 scopus 로고    scopus 로고
    • Postsynaptic BDNF-TrkB signaling in synapse maturation, plasticity and disease
    • Yoshii A and Constantine-Paton M: Postsynaptic BDNF-TrkB signaling in synapse maturation, plasticity and disease. Dev Neurobiol 70: 304-322, 2010.
    • (2010) Dev Neurobiol , vol.70 , pp. 304-322
    • Yoshii, A.1    Constantine-Paton, M.2
  • 12
    • 0033529638 scopus 로고    scopus 로고
    • Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase
    • Hetman M, Kanning K, Cavanaugh JE and Xia Z: Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. J Biol Chem 274: 22569-22580, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 22569-22580
    • Hetman, M.1    Kanning, K.2    Cavanaugh, J.E.3    Xia, Z.4
  • 13
    • 27144508812 scopus 로고    scopus 로고
    • Neuroprotection by BDNF against glutamate-induced apoptotic cell death is mediated by ERK and PI3-kinase pathways
    • Almeida RD, Manadas BJ, Melo CV, et al: Neuroprotection by BDNF against glutamate-induced apoptotic cell death is mediated by ERK and PI3-kinase pathways. Cell Death Differ 12: 1329-1343, 2005.
    • (2005) Cell Death Differ , vol.12 , pp. 1329-1343
    • Almeida, R.D.1    Manadas, B.J.2    Melo, C.V.3
  • 14
    • 0032698075 scopus 로고    scopus 로고
    • Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and-independent mechanisms
    • Bonni A, Brunet A, West AE, Datta SR, Takasu MA and Greenberg ME: Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 286: 1358-1362, 1999.
    • (1999) Science , vol.286 , pp. 1358-1362
    • Bonni, A.1    Brunet, A.2    West, A.E.3    Datta, S.R.4    Takasu, M.A.5    Greenberg, M.E.6
  • 15
    • 0034255042 scopus 로고    scopus 로고
    • BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway
    • Han BH and Holtzman DM: BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway. J Neurosci 20: 5775-5781, 2000.
    • (2000) J Neurosci , vol.20 , pp. 5775-5781
    • Han, B.H.1    Holtzman, D.M.2
  • 16
    • 0034648063 scopus 로고    scopus 로고
    • Neuroprotection by MAPK/ERK kinase inhibition with U0126 against oxidative stress in a mouse neuronal cell line and rat primary cultured cortical neurons
    • Satoh T, Nakatsuka D, Watanabe Y, Nagata I, Kikuchi H and Namura S: Neuroprotection by MAPK/ERK kinase inhibition with U0126 against oxidative stress in a mouse neuronal cell line and rat primary cultured cortical neurons. Neurosci Lett 288: 163-166, 2000.
    • (2000) Neurosci Lett , vol.288 , pp. 163-166
    • Satoh, T.1    Nakatsuka, D.2    Watanabe, Y.3    Nagata, I.4    Kikuchi, H.5    Namura, S.6
  • 17
    • 0036270263 scopus 로고    scopus 로고
    • MEK and ERK protect hypoxic cortical neurons via phosphorylation of Bad
    • Jin K, Mao XO, Zhu Y and Greenberg DA: MEK and ERK protect hypoxic cortical neurons via phosphorylation of Bad. J Neurochem 80: 119-125, 2002.
    • (2002) J Neurochem , vol.80 , pp. 119-125
    • Jin, K.1    Mao, X.O.2    Zhu, Y.3    Greenberg, D.A.4
  • 18
    • 0034666390 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-mediated neuroprotection of adult rat retinal ganglion cells in vivo does not exclusively depend on phosphatidyl-inositol-3′-kinase/protein kinase B signaling
    • Klöcker N, Kermer P, Weishaupt JH, Labes M, Ankerhold R and Bähr M: Brain-derived neurotrophic factor-mediated neuroprotection of adult rat retinal ganglion cells in vivo does not exclusively depend on phosphatidyl-inositol-3′-kinase/protein kinase B signaling. J Neurosci 20: 6962-6967, 2000.
    • (2000) J Neurosci , vol.20 , pp. 6962-6967
    • Klöcker, N.1    Kermer, P.2    Weishaupt, J.H.3    Labes, M.4    Ankerhold, R.5    Bähr, M.6
  • 19
    • 23744455626 scopus 로고    scopus 로고
    • Cellular levels of TrkB and MAPK in the neuroprotective role of BDNF for embryonic rat cortical neurons against hypoxia in vitro
    • Meng M, Zhiling W, Hui Z, Shengfu L, Dan Y and Jiping H: Cellular levels of TrkB and MAPK in the neuroprotective role of BDNF for embryonic rat cortical neurons against hypoxia in vitro. Int J Dev Neurosci 23: 515-521, 2005.
    • (2005) Int J Dev Neurosci , vol.23 , pp. 515-521
    • Meng, M.1    Zhiling, W.2    Hui, Z.3    Shengfu, L.4    Dan, Y.5    Jiping, H.6
  • 20
    • 45849151754 scopus 로고    scopus 로고
    • Peripherally-derived BDNF promotes regeneration of ascending sensory neurons after spinal cord injury
    • Song XY, Li F, Zhang FH, Zhong JH and Zhou XF: Peripherally-derived BDNF promotes regeneration of ascending sensory neurons after spinal cord injury. PLoS One 3: e1707, 2008.
    • (2008) PLoS One , vol.3
    • Song, X.Y.1    Li, F.2    Zhang, F.H.3    Zhong, J.H.4    Zhou, X.F.5
  • 21
    • 0023554682 scopus 로고
    • Ras p21 expression in the progression of breast cancer
    • Fromowitz FB, Viola MV, Chao S, et al: ras p21 expression in the progression of breast cancer. Hum Pathol 18: 1268-1275, 1987.
    • (1987) Hum Pathol , vol.18 , pp. 1268-1275
    • Fromowitz, F.B.1    Viola, M.V.2    Chao, S.3
  • 22
    • 0032763662 scopus 로고    scopus 로고
    • Mild experimental brain injury differentially alters the expression of neurotrophin and neurotrophin receptor mRNAs in the hippocampus
    • Hicks RR, Martin VB, Zhang L and Seroogy KB: Mild experimental brain injury differentially alters the expression of neurotrophin and neurotrophin receptor mRNAs in the hippocampus. Exp Neurol 160: 469-478, 1999.
    • (1999) Exp Neurol , vol.160 , pp. 469-478
    • Hicks, R.R.1    Martin, V.B.2    Zhang, L.3    Seroogy, K.B.4
  • 23
    • 0036271504 scopus 로고    scopus 로고
    • Expression of trkA, trkB and trkC in injured and regenerating retinal ganglion cells of adult rats
    • Cui Q, Tang LS, Hu B, So KF and Yip HK: Expression of trkA, trkB and trkC in injured and regenerating retinal ganglion cells of adult rats. Invest Ophthalmol Vis Sci 43: 1954-1964, 2002.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 1954-1964
    • Cui, Q.1    Tang, L.S.2    Hu, B.3    So, K.F.4    Yip, H.K.5
  • 24
    • 33947387924 scopus 로고    scopus 로고
    • Expression of antiapoptotic and proapoptotic molecules in diabetic retinas
    • Abu El-Asrar AM, Dralands L, Missotten L and Geboes K: Expression of antiapoptotic and proapoptotic molecules in diabetic retinas. Eye (Lond) 21: 238-245, 2007.
    • (2007) Eye (Lond) , vol.21 , pp. 238-245
    • Abu El-Asrar, A.M.1    Dralands, L.2    Missotten, L.3    Geboes, K.4
  • 26
    • 60649112304 scopus 로고    scopus 로고
    • Caspase-dependent retinal ganglion cell apoptosis in the rat model of acute diabetes
    • Li YH, Zhuo YH, Lü L, et al: Caspase-dependent retinal ganglion cell apoptosis in the rat model of acute diabetes. Chin Med J (Engl) 121: 2566-2571, 2008.
    • (2008) Chin Med J (Engl) , vol.121 , pp. 2566-2571
    • Li, Y.H.1    Zhuo, Y.H.2    Lü, L.3
  • 27
    • 41849118420 scopus 로고    scopus 로고
    • Mitochondria-and caspase-dependent cell death pathway involved in neuronal degeneration in diabetic retinopathy
    • Oshitari T, Yamamoto S, Hata N and Roy S: Mitochondria-and caspase-dependent cell death pathway involved in neuronal degeneration in diabetic retinopathy. Br J Ophthalmol 92: 552-556, 2008.
    • (2008) Br J Ophthalmol , vol.92 , pp. 552-556
    • Oshitari, T.1    Yamamoto, S.2    Hata, N.3    Roy, S.4
  • 28
    • 1342325425 scopus 로고    scopus 로고
    • High glucose enhances interleukin-6-induced vascular endothelial growth factor 165 expression via activation of gp130-mediated p44/42 MAPK-CCAAT/enhancer binding protein signaling in gingival fibroblasts
    • Omori K, Naruishi K, Nishimura F, Yamada-Naruishi H and Takashiba S: High glucose enhances interleukin-6-induced vascular endothelial growth factor 165 expression via activation of gp130-mediated p44/42 MAPK-CCAAT/enhancer binding protein signaling in gingival fibroblasts. J Biol Chem 279: 6643-6649, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 6643-6649
    • Omori, K.1    Naruishi, K.2    Nishimura, F.3    Yamada-Naruishi, H.4    Takashiba, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.