Caspase-dependent retinal ganglion cell apoptosis in the rat model of acute diabetes

Chinese Medical Journal

Volumn 121, Issue 24, 2008, Pages 2566-2571

  Li, Yong Hao ^a   Zhuo, Ye Hong ^a   Lü, Lin ^a   Chen, Ling Yan ^a   Huang, Xin Hua ^a   Zhang, Jing Lin ^a   Li, Shi Yi ^a   Wang, Xiang Gui ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Apoptosis; Diabetic retinopathy; Retinal ganglion cell

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE INHIBITOR; STREPTOZOCIN;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME LOCALIZATION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; NERVE FIBER; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RETINA GANGLION CELL; STREPTOZOCIN DIABETES; TISSUE DISTRIBUTION; WESTERN BLOTTING;

EID: 60649112304     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200812020-00018     Document Type: Article

References (29)

1. King H, Aubert RE, Herman WH. Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care 1998; 21: 1414-1431.
2. Amos AF, McCarty D J, Zimmet P. The rising global burden of diabetes and its complications: estimates and projections to the year 2010. Diabet Med 1997; 14 Suppl 5: s1-s85.
3. Barber AJ. A new view of diabetic retinopathy: a neurodegenerative disease of the eye. Prog Neuropsycho-pharmacol Biol Psychiatry 2003; 27: 283-290
4. Fletcher EL, Phipps JA, Wilkinson-Berka JL. Dysfunction of retinal neurons and glia during diabetes. 2005; 88:135-145.
5. Stefanis L. Caspase-dependent and independent neuronal death: two distinct pathways to neuronal injury. Neuroscientist 2005; 11: 50-62.
6. van Loo G, Saelens X, van Gurp M, Macfarlane M, Martin SJ, Vandenabeele P. The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet. Cell Death Differ 2002; 9: 1031-1042.
7. Ravagnan L, Roumier T, Kroemer G Mitochondria, the killer organelles and their weapons. J Cell Physiol 2002; 192: 131-137.
8. Sumioka K, Shirai Y, Sakai N, Hashimoto T, Tanaka C, Yamamoto M, et al. Induction of a 55-kDa PKN cleavage product by ischemia/reperfusion model in the rat re retina. Invest Ophthalmol Vis Sci 2000; 41: 29-35.
9. Chaudhary P, Ahmed F, Quebada P, Sharma SC. Caspase inhibitors block the rectial ganglion cell death following optic nerve transection. Brain Res Mol Brain Res 1999; 67: 36-45.
10. Bloodworth JM Jr. Diabetic retinopathy. Diabetes 1962; 11: 1-22.
11. Simonsen SE. The value of the oscillatory potential in selecting juvenile diabetics at risk of developing proliferative retinopathy. Acta Ophthalmol (copenh) 1980; 58: 865-878.
12. Segawa Y, Shirao Y, Yamagishi S, Higashide T, Kobayashi M, Katsumo K, et al. Upregulation of retinal vascular endotbelial growth factor toRNAs in spontaneously diabetic rats without ophthalmoscopic retinopathy. A possible participation of advanced glycation end products in the development of the early phase of diabetic retinopathy. Ophthalmic Res 1998; 30: 333-339.
13. Holopigian K, Greenstein VC, Seiple W, Hood DC, Carr RE. Evidence for photoreceptor changes in patients with diabetic retinopathy. Invest Ophthalmol Vis Sci 1997; 38: 2355-2365.
14. Aizu Y, Oyanagi K, Hu J, Nakagawa H. Degeneration of retinal neuronal processes and pigment epithelium in the early stage of the streptozotocin-diabetic rats. Neuropathology 2002; 22: 161-170.
15. Hancock HA, Kraft TW. Oscillatory potential analysis and ERGs of normal and diabetic rats. Invest Ophthalmol Vis Sci 2004; 45: 1002-1008.
16. Li Q, Zemel E, Miller B, Perlman I. Early retinal damage in experimental diabetes: electroretinographical and morphological observations. Exp Eye Res 2002; 74: 615-625.
17. Phipps JA, Fleteher EL, Vingrys AJ. Paired-flash identification of rod and cone dysfunction in the diabetic rat. Invest Ophthalmol Vis Sci 2004; 45: 4592-4600.
18. Bui BV, Amitage JA, Tolcos M, Cooper ME, Vingrys AJ. ACE inhibition salvages the visual loss caused by diabetes. Diabetologia 2003; 46: 401-408.
19. Su EN, Alder VA, Yu DY, Yu PK, Cringle SJ, Yogesam K. Continued progression of retinopathy despite spontaneous recovery to normoglycemia in a long-term study of stretozotocin induced diabetes in rats. Graefes Arch Clin Exp Ophthalmo1 2000; 238: 163-173.
20. Dosso AA, Yenice-Ustun F, Sommerhalder J, Golay A, Morel Y, Leuenberger PM. Contrast sensitivity in obese dyslipidemic patients with insulin resistance. Arch Ophthalmol 1998; 116: 1316-1320.
21. Ewing FM, Deary IJ, Strachan MW, Frier BM. Seeing beyond retinopathy in diabetes:electrophysiological and psychophysical abnormalities and alterations in vision. Endocr Rev 1998; 19: 462-476.
22. Park SH, Park JW, Park S J, Kim KY, Chung JW, Chun MH, et al. Apoptotic death of photoreceptors in the streptozotocininduced diabetic rat retina. Diabetologia 2003; 46: 1260-1268.
23. Martin PM, Roon P, Van Ells TK, Ganapathy V, Smith SB. Death of retinal neurons in streptozotocm-induced diabetic mice. Invest Ophthalmol Vis Sci 2004; 45: 3330-3336.
24. Barber AJ, Lieth E, Khin SA, Amonetti DA, Buchanan AG, Gardner TW. Neural apoptosis in the retina during experimental and human diabetes: early onset and effect of insulin, J Clin Invest 1998; 102: 783-791.
25. Barber A J, Antonetti DA, Kern TS, Reiter CE, Soans RS, Krady JK, et al. The Ins2Akita mouse as a model of early retinal complications in diabetes. Invest Ophthalmol Vis Sci 2005; 46: 2210-2218.
26. Abu El-Asrar AM, Dralands L, Missotten L, Geboes K. Expression of antiapoptotic and proapoptotic molecules in diabetic retinas. Eye 2007; 21: 238-245.
27. Kiechle FL, Zhang X. Apoptosis: biohemical aspects and clinical implications. Clin Chim Acta 2002; 326: 27-45.
28. Mohr S, Xi X, Tang J, Kern TS. Caspase activation in retinas of diabetic and galactosemic mice and diabetic patients. Diabetes 2002; 51: 1172-1179.
29. Oshitari T, Yamamoto S, Hata N, Roy S. Mitochondria - and caspase-dependent cell death pathway involved in neuronal degeneration in diabetic retinopathy. Br J Ophthalmol 2008; 92: 552-556.