Inhibition of ADAM-17 more effectively down-regulates the Notch pathway than that of γ-secretase in renal carcinoma

Journal of Experimental and Clinical Cancer Research

Volumn 32, Issue 1, 2013, Pages

  Guo, Zhen ^a   Jin, Xunbo ^a   Jia, Haiyan ^b  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^b Pharmacy of Shandong Traffic Hospital   (China)

Author keywords

secretase; ADAM 17; Apoptosis; Marimastat; Notch; Renal cell cancer

Indexed keywords

DAPT; MARIMASTAT; NOTCH1 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME INHIBITOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADAM PROTEINS; AMYLOID PRECURSOR PROTEIN SECRETASES; APOPTOSIS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; HOMEODOMAIN PROTEINS; HUMANS; HYDROXAMIC ACIDS; KIDNEY NEOPLASMS; NEOPLASM STAGING; RECEPTOR, NOTCH1; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84877140631     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-32-26     Document Type: Article

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