The Second Intracellular Loop of the Human Cannabinoid CB2 Receptor Governs G Protein Coupling in Coordination with the Carboxyl Terminal Domain

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Zheng, Congxia ^a,c   Chen, Linjie ^a   Chen, Xiaopan ^a   He, Xiaobai ^a   Yang, Jingwen ^b   Shi, Ying ^a   Zhou, Naiming ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG INTERNATIONAL STUDIES UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CANNABINOID 2 RECEPTOR; CHIMERIC PROTEIN; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; LEUCINE; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROLINE;

AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELLULAR PARAMETERS; CONTROLLED STUDY; COUPLING FACTOR; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INTRACELLULAR LOOP; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS REGULATION;

ADENYLATE CYCLASE; AMINO ACID SEQUENCE; CELL MEMBRANE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GTP-BINDING PROTEINS; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PROLINE; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, CANNABINOID, CB1; RECEPTOR, CANNABINOID, CB2; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84877131934     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063262     Document Type: Article

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