Chimeric exchanges within the bradykinin B2 receptor intracellular face with the prostaglandin EP2 receptor as the donor: Importance of the second intracellular loop for cAMP synthesis

Archives of Biochemistry and Biophysics

Volumn 415, Issue 1, 2003, Pages 54-62

  Pal Ghosh, Ruma ^a   Yu, Jun ^a   Prado, Gregory N ^a   Taylor, Linda ^a   Mierke, Dale F ^b,c   Polgar, Peter ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Division of Biology and Medicine   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

Arachidonic acid; Bradykinin; Bradykinin B2 receptors; cAMP; Chimeras; Endocytosis; G protein coupled receptors; Global mutations; Inositolphosphates; Mutagenesis; PGE2 EP2 receptors; Phosphatydilinositol; Point mutations; Prostaglandin E2

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BRADYKININ B2 RECEPTOR; CELL PROTEIN; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; HELIX LOOP HELIX PROTEIN; HISTIDYLPROLYLTYROSYLPHENYLALANYLGLUTAMINE; HYBRID PROTEIN; PEPTIDE; PHOSPHATIDYLINOSITOL; PROSTAGLANDIN E RECEPTOR; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHIMERA; CONTROLLED STUDY; ENDOCYTOSIS; HUMAN; INTERNALIZATION; LIPID METABOLISM; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTEIN TRANSPORT; RAT; RECEPTOR UPREGULATION; WILD TYPE;

AVIAN LEUKOSIS VIRUS;

EID: 0038511357     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9861(03)00217-0     Document Type: Article

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