Thymidine-dependent attenuation of the mitochondrial apoptotic pathway in adenosine-induced apoptosis of HL-60 cells

Journal of Cancer Research and Clinical Oncology

Volumn 127, Issue 9, 2001, Pages 570-576

  Kang, Chang Mo ^a   Suh, Yousin ^a   Jang, Ik Soon ^a   Park, Sang ^a  

^a Seoul National University College of Medicine   (South Korea)

Author keywords

Adenosine; Apoptosis; Bax translocation; Cytochrome c; Mitochondria; Thymidine

Indexed keywords

ADENOSINE; CASPASE 3; CASPASE 9; CYTOCHROME C; DNA FRAGMENT; MATRIX METALLOPROTEINASE; PROTEIN BAX; THYMIDINE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; HUMAN; HUMAN CELL; INCUBATION TIME; INTRACELLULAR TRANSPORT; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ADENOSINE; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELL SURVIVAL; CYTOCHROME C GROUP; DRUG INTERACTIONS; HL-60 CELLS; HUMANS; INTRACELLULAR MEMBRANES; MEMBRANE POTENTIALS; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; THYMIDINE;

EID: 0034880557     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004320100264     Document Type: Article

References (43)

1. Inhibition of Bax channel-forming activity by Bcl-2
2. Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane
3. Caspases induce cytochrome c release from mitochondria by activating cytosolic factors
4. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
5. Oxidative stress as a mediator of apoptosis
6. Modulation of cell death by Bcl-xL through caspase interaction
7. Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by BclxL
8. Collapse of the inner mitochondrial transmembrane potential is not required for apoptosis of HL60 cells
9. Mitochondria and apoptosis
10. Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis
11. In vitro effect of extracellular AMP on MCF-7 breast cancer cells: Inhibition of glycolysis and cell proliferation
12. The effect of pyrimidine nucleosides on adenosine-induced apoptosis in HL-60 cells
13. The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
14. The mitochondrial death life regulator in apoptosis and necrosis
15. Mitochondrial depolarization is not required for neuronal apoptosis
16. Epidermal growth factor protects GH3 cells from adenosine induced growth arrest
17. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
18. Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
19. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
20. Mitochondrial permeability transition is a central coordinating event of apoptosis
21. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
22. The permeability transition pore complex: A target for apoptosis regulation by caspases and bcl-2-related proteins
23. Caspases disrupt mitochondrial membrane barrier function
24. Bcl-x(L) forms an ion channel in synthetic lipid membranes
25. Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria
26. Uptake and metabolism of adenosine by pig aortic endothelial and smooth-muscle cells in culture
27. Cytochrome c: Can't live with it - Can't live without it
28. Bcl-2 family proteins and mitochondria
29. Mitochondrial membrane potential monitored by JC-1 dye
30. Channel formation by antiapoptotic protein Bcl-2
31. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
32. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
33. The central executioner of apoptosis: Multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis
34. Apoptosis induced by adenosine in human leukemia HL-60 cells
35. A novel human nucleoside diphosphate (NDP) kinase, Nm23-H6, localizes in mitochondria and affects cytokinesis
36. Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange
37. Adenosine-induced apoptosis in chick embryonic sympathetic neurons: A new physiological role for adenosine
38. Growth inhibition of transformed mouse fibroblasts by adenine nucleotides occurs via generation of extracellular adenosine
39. Movement of Bax from the cytosol to mitochondria during apoptosis
40. Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
41. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
42. Mitochondrial control of nuclear apoptosis
43. The mitochondrial permeability transition