Unique arylalkylamine N-acetyltransferase-2 polymorphism in salmonids and profound variations in thermal stability and catalytic efficiency conferred by two residues

Journal of Experimental Biology

Volumn 216, Issue 10, 2013, Pages 1938-1948

  Cazamea Catalan D ^a,b   Magnanou, E ^a,b   Helland, R ^c   Besseau, L ^a,b   Boeuf, G ^a,b,d   Falcon J ^a,b   Jorgensen E H ^c  

^a SORBONNE UNIVERSITÉ   (France)

^b France   (France)

^c UNIVERSITY OF TROMSØ   (Norway)

^d MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

Author keywords

3D structure; AANAT2; Adaptation; Kinetics; Melatonin; Pineal gland; Teleost; Three dimensional structure

Indexed keywords

AMINO ACID; ARALKYLAMINE ACETYLTRANSFERASE; MELATONIN;

3D STRUCTURE; AANAT2; ADAPTATION; AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BIOCATALYSIS; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME STABILITY; GENETIC POLYMORPHISM; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; PINEAL BODY; PROTEIN SECONDARY STRUCTURE; SALMONID; STRUCTURE ACTIVITY RELATION; TELEOST; TEMPERATURE; THREE-DIMENSIONAL STRUCTURE;

3D STRUCTURE; AANAT2; ADAPTATION; KINETICS; MELATONIN; PINEAL GLAND; TELEOST; THREE-DIMENSIONAL STRUCTURE;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; ARYLALKYLAMINE N-ACETYLTRANSFERASE; BIOCATALYSIS; ENZYME STABILITY; KINETICS; MELATONIN; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; PROTEIN STRUCTURE, SECONDARY; SALMONIDAE; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

ONCORHYNCHUS MYKISS; SALMONIDAE; SALVELINUS ALPINUS; SALVELINUS FONTINALIS; TELEOSTEI;

EID: 84877105223     PISSN: 00220949     EISSN: None     Source Type: Journal    
DOI: 10.1242/jeb.080960     Document Type: Article

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